flucytosine and ganciclovir

flucytosine has been researched along with ganciclovir in 73 studies

Research

Studies (73)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (16.44)	18.2507
2000's	38 (52.05)	29.6817
2010's	23 (31.51)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Austin, EA; Huber, BE; Knick, VC; Murray, DM; Trinh, QT	1
Comstock, KE; Ge, JQ; Hoganson, DK; Holley-Guthrie, E; Kenney, S; Olsen, JC; Rogers, RP	1
Freytag, SO; Kim, JH; Kim, SH; Rogulski, KR	1
Aghi, M; Breakefield, XO; Chiocca, EA; Chou, TC; Kramm, CM	1
Blackburn, RV; Corry, PM; Galoforo, SS; Lee, YJ	2
Ge, K; Liu, XY; Sun, LY; Xu, DH; Xu, LF; Zheng, ZC	1
Freytag, SO; Kim, JH; Kolozsvary, A; Rogulski, KR; Zhang, K	1
Chang, WS; Liao, WC; Wu, FY	1
Akahane, T; Fukui, H; Kojima, H; Kuriyama, S; Mitoro, A; Nakatani, T; Okamoto, S; Toyokawa, Y; Tsujinoue, H; Yamazaki, M	1
Freytag, SO; Gilbert, JD; Kim, JH; Xie, Y	1
Chang, JW; Chung, SS; Kim, E; Kim, JH; Lee, H; Lee, Y	1
Cui, Q; Liu, T; Zhang, L	1
Hayakawa, M; Suzuki, S; Tadakuma, T; Yoshimura, I	1
Chen, MJ; Chung-Faye, GA; Kerr, DJ; Searle, PF; Young, LS	1
Cowman, AF; Duraisingh, MT; Triglia, T	1
Borrelli, MJ; Lee, H; Lee, YJ	1
Brunicardi, FC; Fisher, WE; Yazawa, K	1
Cohen, JB; Glorioso, JC; Miura, F; Moriuchi, S; Tamura, M; Wolfe, D; Yoshimine, T	1
Cooperwood, JS; Ko, DH; Lee, HJ; You, Z	1
Aguilar-Cordova, E; Barton, K; Brown, S; DePeralta-Venturina, M; Freytag, SO; Khil, M; Kim, JH; Lu, M; Menon, M; Nafziger, D; Paielli, D; Peabody, J; Pegg, J; Stricker, H	1
Chen, SS; Li, XJ; Qian, GX; Wang, KM; Wang, ZH; Xia, AD; Xu, Y	1
Cao, HQ; Ding, JF; Meng, XM; Zhao, Y	1
Liu, CS; Ma, DX; Xu, CX; Xu, ZS; Zhang, DQ; Zhang, HQ	1
Chen, XL; Jiang, YR; Liu, CS; Ma, DX	2
Brown, S; DePeralta-Venturina, M; Freytag, SO; Kim, JH; Lu, M; Paielli, D; Peabody, J; Pegg, J; Pradhan, DG; Stricker, H; Xia, X	1
Kuriyama, S; Tsujinoue, H; Yoshiji, H	1
Becker, G; Braun, K; Corban-Wilhelm, H; Debus, J; Ehemann, V; Greulich, D	1
Aprahamian, M; Hajri, A; Lehn, JM; Lehn, P; Marescaux, J; Vigneron, JP; Wack, S	1
Jiang, S; Kong, BH; Ma, DX; Qu, X; Song, Y	1
Cai, F; Chen, Z; Dai, H; Feng, Y; Liang, D; Long, Z; Pan, Q; Tang, A; Wu, L; Xia, J; Xia, K; Zhang, J; Zhao, S	1
Fischer, U; Frank, S; Kramm, CM; Rainov, NG; Schulze-Osthoff, K; Steffens, S	1
Boucher, PD; Freytag, SO; Im, MM; Shewach, DS	1
Tan, WL; Wu, YD; Xie, Y; Zheng, SB; Zhu, WH	1
Khatri, A; Russell, PJ	1
Huang, ZH; Li, Q; Li, Z; Su, GQ; Yu, JL	1
Chen, WN; Chen, XL; Jiang, YR; Lai, YC; Liu, CS; Ma, DX; Qi, MH; Wan, DS	1
Chen, HJ; Huang, ZH; Su, GQ; Wu, AG; Yu, JL	1
Chen, HJ; Han, XJ; Huang, ZH; Kong, H; Li, Z; Yu, JL	1
Altaner, C	1
Huang, ZH; Kong, H; Li, Q; Li, Z; Yang, LC; Yu, JL	1
Bertin, S; Düzgüneş, N; Faneca, H; Konopka, K; Neves, S; Pedroso de Lima, MC; Pierrefite-Carle, V; Simões, S	1
Aref, I; Barton, KN; Brown, SL; Elshaikh, M; Freytag, SO; Karvelis, KC; Kim, JH; Lu, M; Movsas, B; Pegg, J; Siddiqui, F; Stricker, H; Zhang, Y	1
Wang, X; Wu, H; Yan, XR; Yu, HT; Zhang, Y	1
Dachs, GU; Hunt, MA; Patterson, AV; Singleton, DC; Syddall, S	1
Lu, YC; Luo, YP; Tai, CK; Wang, YW	1
Barton, K; Freytag, SO; Kim, JH; Lu, M; Movsas, B; Stricker, H	1
Chen, LR; Li, XH; Qian, Y; Tian, SM; Wang, LH; Zhang, P; Zhou, P	1
He, JX; Li, FL; Liu, QC; Peng, GL; Qiu, Y; Zou, XS	1
Choi, KC; Hwang, KA; Jeung, EB; Kang, NH; Kim, SU; Lee, HJ; Yi, BR	1
Huang, ZH; Su, G; Su, GQ	1
Choi, KC; Choi, KJ; Kim, SU; Yi, BR	1
Altaner, C; Altanerova, V	1
Ito, M; Iwami, K; Kim, SU; Kinjo, S; Lee, HJ; Momota, H; Motomura, K; Natsume, A; Nishimira, Y; Ohka, F; Ohno, M; Wakabayashi, T; Wang, C	1
Baranovicova, L; Durinikova, E; Hunakova, L; Kozovska, Z; Kucerova, L; Matuskova, M; Nencka, R; Pastorakova, A; Waczulikova, I	1
Du, J; Huang, Z; Kong, H; Li, Q; Qi, K; Tao, L; Wang, Y	1
Chen, Y; Cui, Y; Jiang, C; Li, D; Li, N; Liu, H; Niu, J; Peng, H; Xing, C; Yan, C; Yang, H	1
Dong, XY; Fang, ZG; Huang, RW; Li, XD; Lin, DJ; Liu, JJ; Pan, GJ; Wang, WQ; Xiao, RZ; Zhao, Y	1
Feng, QZ; Huang, ZJ; Luo, Q; Luo, WY; Xu, L; Yi, WC; You, J; Zeng, YY	1
Bastide, C; Bruyère, F; Chandenier, J; Desoubeaux, G; Fourcade, C; Guy, L; Karsenty, G; Lachaud, L; Lavigne, JP; Malavaud, S; Sotto, A	1
Davoudi, N; Khamesipour, A; Mahboudi, F; McMaster, WR	1
Huang, Z; Kong, H; Li, Q; Liu, C; Yang, L; Zhu, T	1
Abd-El-Barr, M; Aljuboori, Z; Anderson, JE; Chi, JH; Han, I; Haragopal, H; Kim, SU; Lee, HJ; Ropper, AE; Sidman, RL; Snyder, EY; Teng, YD; Viapiano, MS; Zeng, X	1

Reviews

10 review(s) available for flucytosine and ganciclovir

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Gene therapy for colorectal cancer: therapeutic potential. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 2001, Volume: 15, Issue:6 Topics: Adenoviridae; Antigen Presentation; Aziridines; Carcinoembryonic Antigen; Clinical Trials as Topic; Colorectal Neoplasms; Flucytosine; Ganciclovir; Genes, p53; Genetic Therapy; Humans; T-Lymphocytes, Cytotoxic	2001
Current progress in suicide gene therapy for cancer. World journal of surgery, 2002, Volume: 26, Issue:7 Topics: Animals; Antiviral Agents; Arabinonucleosides; Aziridines; Clinical Trials as Topic; Cytosine Deaminase; Escherichia coli; Flucytosine; Ganciclovir; Genetic Therapy; Genetic Vectors; Herpesvirus 3, Human; Humans; Neoplasms; Nitroreductases; Nucleoside Deaminases; Pentosyltransferases; Prodrugs; Purine Nucleosides; Simplexvirus; Thymidine Kinase; Xanthines	2002
Prodrug and antedrug: two diametrical approaches in designing safer drugs. Archives of pharmacal research, 2002, Volume: 25, Issue:2 Topics: Cytosine Deaminase; Drug Design; Flucytosine; Ganciclovir; Genetic Therapy; Immunoconjugates; Nucleoside Deaminases; Nucleosides; Nucleotides; Prodrugs; Thymidine Kinase	2002
Novel gene-directed enzyme prodrug therapies against prostate cancer. Expert opinion on investigational drugs, 2006, Volume: 15, Issue:8 Topics: Animals; Antineoplastic Agents; Bystander Effect; Clinical Trials as Topic; Combined Modality Therapy; Cyclophosphamide; Cytochrome P-450 Enzyme System; Cytosine Deaminase; Flucytosine; Ganciclovir; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Male; Prodrugs; Prostatic Neoplasms; Thymidine Kinase	2006
Prodrug cancer gene therapy. Cancer letters, 2008, Nov-08, Volume: 270, Issue:2 Topics: Animals; Antineoplastic Agents; Cytochrome P-450 Enzyme System; Cytosine Deaminase; Enzymes; Flucytosine; Ganciclovir; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Neoplasms; Prodrugs; Thymidine Kinase	2008
Bystander or no bystander for gene directed enzyme prodrug therapy. Molecules (Basel, Switzerland), 2009, Nov-10, Volume: 14, Issue:11 Topics: Animals; Aziridines; Cytosine Deaminase; Flucytosine; Ganciclovir; Genetic Therapy; Humans; Nitroreductases; Prodrugs; Thymidine Kinase	2009
Therapeutic potential of stem cells expressing suicide genes that selectively target human breast cancer cells: evidence that they exert tumoricidal effects via tumor tropism (review). International journal of oncology, 2012, Volume: 41, Issue:3 Topics: Breast Neoplasms; Camptothecin; Cytosine Deaminase; Female; Flucytosine; Fluorouracil; Ganciclovir; Genes, Transgenic, Suicide; Genetic Engineering; Genetic Therapy; Humans; Irinotecan; Prodrugs; Stem Cells; Thymidine Kinase	2012
Stem cell based glioblastoma gene therapy. Neoplasma, 2012, Volume: 59, Issue:6 Topics: Animals; Cytosine Deaminase; Flucytosine; Ganciclovir; Genetic Therapy; Glioblastoma; Humans; Mesenchymal Stem Cells; Simplexvirus; Thymidine Kinase	2012
[Non-antibiotic anti-infectious treatments in urology]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23, Issue:15 Topics: Acyclovir; Albendazole; Amphotericin B; Anti-Infective Agents; Caspofungin; Cidofovir; Cytosine; Echinocandins; Fluconazole; Flucytosine; Foscarnet; Ganciclovir; Humans; Ivermectin; Lipopeptides; Organophosphonates; Praziquantel; Urologic Diseases; Valganciclovir	2013

Trials

4 trial(s) available for flucytosine and ganciclovir

Article	Year
Phase I study of replication-competent adenovirus-mediated double suicide gene therapy for the treatment of locally recurrent prostate cancer. Cancer research, 2002, Sep-01, Volume: 62, Issue:17 Topics: Adenoviruses, Human; Aged; Aged, 80 and over; Biopsy; Cytosine Deaminase; DNA, Viral; Flucytosine; Ganciclovir; Genetic Therapy; Herpesvirus 1, Human; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Nucleoside Deaminases; Prodrugs; Prostate-Specific Antigen; Prostatic Neoplasms; Thymidine Kinase; Virus Replication; Virus Shedding	2002
Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy in combination with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer. Cancer research, 2003, Nov-01, Volume: 63, Issue:21 Topics: Adenoviruses, Human; Aged; Aged, 80 and over; Combined Modality Therapy; Cytosine Deaminase; DNA, Viral; Flucytosine; Ganciclovir; Gene Expression; Genetic Therapy; Humans; Male; Middle Aged; Prostatic Neoplasms; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase; Transgenes; Valganciclovir; Virus Replication	2003
Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate. Molecular therapy : the journal of the American Society of Gene Therapy, 2008, Volume: 16, Issue:10 Topics: Adenoviridae; Aged; Cohort Studies; Flucytosine; Ganciclovir; Gene Expression; Genetic Vectors; Humans; Male; Middle Aged; Prostate; Tomography, Emission-Computed, Single-Photon; Valganciclovir	2008
Adaptive seamless design for an efficacy trial of replication-competent adenovirus-mediated suicide gene therapy and radiation in newly-diagnosed prostate cancer (ReCAP Trial). Contemporary clinical trials, 2011, Volume: 32, Issue:3 Topics: Adenoviridae; Antimetabolites; Antiviral Agents; Combined Modality Therapy; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; Kaplan-Meier Estimate; Male; Prostatic Neoplasms; Quality of Life; Radiotherapy, Intensity-Modulated; Sample Size; Treatment Outcome; Valganciclovir; Virus Replication	2011

Other Studies

59 other study(ies) available for flucytosine and ganciclovir

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Enzyme/prodrug gene therapy: comparison of cytosine deaminase/5-fluorocytosine versus thymidine kinase/ganciclovir enzyme/prodrug systems in a human colorectal carcinoma cell line. Cancer research, 1995, Nov-01, Volume: 55, Issue:21 Topics: Animals; Antimetabolites, Antineoplastic; Base Sequence; Colorectal Neoplasms; Cytosine Deaminase; Drug Screening Assays, Antitumor; Flucytosine; Ganciclovir; Genetic Therapy; Humans; Mice; Mice, Nude; Microscopy, Electron; Molecular Sequence Data; Neoplasm Transplantation; Nucleoside Deaminases; Prodrugs; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured	1995
Killing Epstein-Barr virus-positive B lymphocytes by gene therapy: comparing the efficacy of cytosine deaminase and herpes simplex virus thymidine kinase. Human gene therapy, 1996, Dec-01, Volume: 7, Issue:18 Topics: Animals; B-Lymphocytes; Cell Line, Transformed; Cytosine Deaminase; Escherichia coli; Female; Flucytosine; Ganciclovir; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Herpesvirus 4, Human; Humans; Lymphoma, B-Cell; Mice; Mice, SCID; Nucleoside Deaminases; Prodrugs; Retroviridae; Simplexvirus; Thymidine Kinase	1996
Glioma cells transduced with an Escherichia coli CD/HSV-1 TK fusion gene exhibit enhanced metabolic suicide and radiosensitivity. Human gene therapy, 1997, Jan-01, Volume: 8, Issue:1 Topics: Blotting, Western; Bromodeoxyuridine; Cytosine; Cytosine Deaminase; Deoxyuridine; Enzyme Inhibitors; Escherichia coli; Flucytosine; Ganciclovir; Gene Expression Regulation, Viral; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Gliosarcoma; Humans; Nucleoside Deaminases; Prodrugs; Radiation Tolerance; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured	1997
Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. Journal of the National Cancer Institute, 1998, Mar-04, Volume: 90, Issue:5 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cytosine Deaminase; Flucytosine; Fluorouracil; Ganciclovir; Genetic Therapy; Gliosarcoma; Humans; Mice; Mice, Nude; Mitosis; Nucleoside Deaminases; Phosphorylation; Prodrugs; Rats; Thymidine Kinase; Tumor Cells, Cultured	1998
Adenoviral-mediated transfer of a heat-inducible double suicide gene into prostate carcinoma cells. Cancer research, 1998, Apr-01, Volume: 58, Issue:7 Topics: Adenoviridae; Antimetabolites; Antiviral Agents; Cytosine Deaminase; Enzyme Activation; Escherichia coli; Flucytosine; Ganciclovir; Gene Expression Regulation, Enzymologic; Gene Transfer Techniques; Genetic Therapy; Herpesvirus 1, Human; Hot Temperature; Humans; Male; Nucleoside Deaminases; Prostatic Neoplasms; Recombinant Fusion Proteins; Thymidine Kinase	1998
The use of suicide gene systems in vascular cells in vitro. Cell research, 1998, Volume: 8, Issue:1 Topics: Animals; Cell Division; Cell Line; Cytosine Deaminase; Endothelium, Vascular; Flucytosine; Ganciclovir; Genetic Vectors; Mice; Neovascularization, Physiologic; Nucleoside Deaminases; Prodrugs; Retroviridae; Thymidine Kinase	1998
Pronounced antitumor effects and tumor radiosensitization of double suicide gene therapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 1997, Volume: 3, Issue:11 Topics: Animals; Combined Modality Therapy; Flucytosine; Ganciclovir; Genetic Therapy; Gliosarcoma; Herpesvirus 1, Human; Mice; Mice, Nude; Prodrugs; Rats; Recombinant Fusion Proteins; Thymidine Kinase; Time Factors; Transplantation, Heterologous; Tumor Cells, Cultured	1997
Re: Synergistic anticancer effects of ganciclovir/thymidine kinase and 5-fluorocytosine/cytosine deaminase gene therapies. Journal of the National Cancer Institute, 1999, Feb-03, Volume: 91, Issue:3 Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Brain Neoplasms; Cytosine Deaminase; Drug Synergism; Flucytosine; Ganciclovir; Genetic Therapy; Genetic Vectors; Gliosarcoma; Nucleoside Deaminases; Prodrugs; Rats; Retroviridae; Thymidine Kinase	1999
Adenoviral transduction of a cytosine deaminase/thymidine kinase fusion gene into prostate carcinoma cells enhances prodrug and radiation sensitivity. International journal of cancer, 1999, Jul-19, Volume: 82, Issue:2 Topics: Adenoviridae; Animals; Antimetabolites; Antimetabolites, Antineoplastic; Antiviral Agents; Carcinoma; Cytomegalovirus; Cytosine Deaminase; Flucytosine; Ganciclovir; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; Genetic Therapy; Genetic Vectors; Humans; Male; Nucleoside Deaminases; Prodrugs; Promoter Regions, Genetic; Prostatic Neoplasms; Radiation Tolerance; Rats; Recombinant Fusion Proteins; Thymidine Kinase; Tumor Cells, Cultured	1999
Comparison of gene therapy with the herpes simplex virus thymidine kinase gene and the bacterial cytosine deaminase gene for the treatment of hepatocellular carcinoma. Scandinavian journal of gastroenterology, 1999, Volume: 34, Issue:10 Topics: Animals; Antifungal Agents; Antiviral Agents; Carcinoma, Hepatocellular; Cytosine Deaminase; Escherichia coli; Female; Flucytosine; Ganciclovir; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Nucleoside Deaminases; Prodrugs; Simplexvirus; Statistics, Nonparametric; Thymidine Kinase; Tumor Cells, Cultured	1999
Efficacy of adenovirus-mediated CD/5-FC and HSV-1 thymidine kinase/ganciclovir suicide gene therapies concomitant with p53 gene therapy. Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:12 Topics: Adenoviridae; Animals; Antiviral Agents; Cytosine Deaminase; Female; Flucytosine; Ganciclovir; Genes, p53; Genetic Therapy; Genetic Vectors; Herpesvirus 1, Human; Humans; Male; Mice; Mice, Nude; Mice, SCID; Neoplasm Transplantation; Nucleoside Deaminases; Ovarian Neoplasms; Thymidine Kinase; Tumor Cells, Cultured; Tumor Suppressor Protein p53	1999
Combined antitumor effects of an adenoviral cytosine deaminase/thymidine kinase fusion gene in rat C6 glioma. Neurosurgery, 2000, Volume: 47, Issue:4 Topics: Adenoviridae; Animals; Antimetabolites; Antiviral Agents; Artificial Gene Fusion; Brain Neoplasms; Combined Modality Therapy; Cytosine Deaminase; Feasibility Studies; Female; Flucytosine; Ganciclovir; Glioma; Neoplasm Transplantation; Nucleoside Deaminases; Rats; Rats, Wistar; Recombinant Fusion Proteins; Thymidine Kinase; Transduction, Genetic; Tumor Cells, Cultured	2000
[The killing effects of two prodrug sensitivity genes on human pancreatic carcinoma cells PC-2]. Zhonghua bing li xue za zhi = Chinese journal of pathology, 1998, Volume: 27, Issue:6 Topics: Cell Division; Cytosine Deaminase; Escherichia coli; Flucytosine; Ganciclovir; Genetic Therapy; Nucleoside Deaminases; Pancreatic Neoplasms; Prodrugs; Retroviridae; Simplexvirus; Thymidine Kinase; Transfection; Tumor Cells, Cultured	1998
Suicide gene therapy on LNCaP human prostate cancer cells. International journal of urology : official journal of the Japanese Urological Association, 2001, Volume: 8, Issue:7 Topics: Antimetabolites; Antiviral Agents; Cytosine Deaminase; Escherichia coli; Flucytosine; Ganciclovir; Genetic Therapy; Humans; Male; Nucleoside Deaminases; Promoter Regions, Genetic; Prostatic Neoplasms; Simplexvirus; Thymidine Kinase; Transfection; Tumor Cells, Cultured	2001
Negative selection of Plasmodium falciparum reveals targeted gene deletion by double crossover recombination. International journal for parasitology, 2002, Volume: 32, Issue:1 Topics: Animals; Antimalarials; Antimetabolites; Antiviral Agents; Blotting, Southern; Cytosine Deaminase; DNA, Protozoan; Electrophoresis, Polyacrylamide Gel; Flucytosine; Ganciclovir; Gene Deletion; Malaria, Falciparum; Nucleoside Deaminases; Plasmids; Plasmodium falciparum; Recombination, Genetic; Thymidine Kinase; Triazines	2002
Gene transfer into human prostate adenocarcinoma cells with an adenoviral vector: Hyperthermia enhances a double suicide gene expression, cytotoxicity and radiotoxicity. Cancer gene therapy, 2002, Volume: 9, Issue:3 Topics: Adenocarcinoma; Adenoviridae; Antiviral Agents; Cell Survival; Cytosine Deaminase; Drug Synergism; Flucytosine; Ganciclovir; Gene Expression; Gene Transfer Techniques; Genetic Vectors; Herpesvirus 1, Human; Humans; Hyperthermia, Induced; Male; Nucleoside Deaminases; Prostatic Neoplasms; Radiotherapy; Recombinant Fusion Proteins; Thymidine Kinase	2002
Double suicide gene therapy using a replication defective herpes simplex virus vector reveals reciprocal interference in a malignant glioma model. Gene therapy, 2002, Volume: 9, Issue:9 Topics: Animals; Antiviral Agents; Cytosine Deaminase; Escherichia coli; Female; Flucytosine; Ganciclovir; Genetic Therapy; Genetic Vectors; Glioma; Models, Animal; Nucleoside Deaminases; Rats; Rats, Inbred F344; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured	2002
[Ionizing radiation-regulated killing of human hepatoma cells by liposome-mediated CDglyTK gene delivery]. Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica, 2003, Volume: 35, Issue:1 Topics: Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Cell Survival; Cytomegalovirus; Cytosine Deaminase; DNA-Binding Proteins; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Early Growth Response Protein 1; Flucytosine; Gamma Rays; Ganciclovir; Gene Expression Regulation, Neoplastic; Humans; Immediate-Early Proteins; Liposomes; Nucleoside Deaminases; Plasmids; Promoter Regions, Genetic; Thymidine Kinase; Transcription Factors; Transfection; Tumor Cells, Cultured	2003
[Killing effect of human pulmonary adenocarcinoma cells with TK + CD/5-Fc + GCV coexpression suicide gene systems]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2001, Volume: 23, Issue:2 Topics: Cell Line, Tumor; Cytosine Deaminase; Flucytosine; Ganciclovir; Genetic Therapy; Genetic Vectors; Humans; Lung Neoplasms; Thymidine Kinase; Transfection	2001
[Toxic effects of HSV-TK and CD-TK suicidal gene systems on prostate carcinoma cells]. Ai zheng = Aizheng = Chinese journal of cancer, 2003, Volume: 22, Issue:8 Topics: Cell Line, Tumor; Cytosine Deaminase; Flucytosine; Ganciclovir; Genetic Therapy; Humans; Male; Prostatic Neoplasms; Recombinant Fusion Proteins; Simplexvirus; Thymidine Kinase	2003
[Killing effect of double suicide genes mediated by lentivirus on lymphoma cells]. Ai zheng = Aizheng = Chinese journal of cancer, 2003, Volume: 22, Issue:9 Topics: Cytosine Deaminase; Dose-Response Relationship, Drug; Flucytosine; Ganciclovir; Genetic Therapy; Humans; Lentivirus; Lymphoma; Simplexvirus; Thymidine Kinase	2003
Immune response to suicide gene therapy. Methods in molecular medicine, 2004, Volume: 90 Topics: Animals; Biotransformation; Bystander Effect; Enzymes; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Humans; Neoplasms; Prodrugs; Simplexvirus; T-Lymphocytes; Thymidine Kinase	2004
Comparison of different methods to assess the cytotoxic effects of cytosine deaminase and thymidine kinase gene therapy. Cancer gene therapy, 2004, Volume: 11, Issue:3 Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; Cytosine Deaminase; Escherichia coli; Flucytosine; Ganciclovir; Gene Transfer Techniques; Genes, Transgenic, Suicide; Genetic Therapy; Herpesvirus 1, Human; Male; Prostatic Neoplasms; Rats; Recombinant Fusion Proteins; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Toxicity Tests; Tumor Stem Cell Assay	2004
Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes. Cancer gene therapy, 2004, Volume: 11, Issue:1 Topics: Animals; Biopsy; Carcinoembryonic Antigen; Cell Division; Cell Line, Tumor; Cholesterol; Cytosine Deaminase; Disease Progression; Escherichia coli; Female; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Guanidines; Humans; Liposomes; Mice; Mice, Nude; Pancreatic Neoplasms; Peritoneal Cavity; RNA, Messenger; Simplexvirus; Thymidine Kinase; Transfection	2004
[Establishment of lentivirus-mediated system of double suicide genes and its killing effects on K562 cells]. Zhongguo shi yan xue ye xue za zhi, 2004, Volume: 12, Issue:1 Topics: Cytosine Deaminase; Flucytosine; Ganciclovir; Genetic Therapy; Genetic Vectors; HIV-1; Humans; K562 Cells; Thymidine Kinase	2004
[In vitro treatment of ovarian cancer cells with cytosine deaminase-thymidine kinase fusion disuicide gene therapy system under the control of human telomerase reverse transcriptase gene promoter]. Zhonghua fu chan ke za zhi, 2004, Volume: 39, Issue:6 Topics: Cystadenocarcinoma, Serous; Cytosine Deaminase; DNA-Binding Proteins; Female; Flucytosine; Ganciclovir; Genetic Therapy; Humans; Ovarian Neoplasms; Promoter Regions, Genetic; Telomerase; Thymidine Kinase; Transfection; Tumor Cells, Cultured	2004
A novel fusion suicide gene yeast CDglyTK plays a role in radio-gene therapy of nasopharyngeal carcinoma. Cancer gene therapy, 2004, Volume: 11, Issue:12 Topics: Analysis of Variance; Animals; Blotting, Western; Carcinoma; Combined Modality Therapy; Cytosine Deaminase; Flucytosine; Ganciclovir; Genes, Fungal; Genes, Transgenic, Suicide; Genetic Therapy; Herpesvirus 1, Human; Humans; Mice; Mice, Inbred BALB C; Nasopharyngeal Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Thymidine Kinase; Transfection; Tumor Cells, Cultured; Yeasts	2004
Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells. Oncogene, 2005, Feb-10, Volume: 24, Issue:7 Topics: Animals; Apoptosis; Cell Line, Tumor; Cytosine Deaminase; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Glioma; Humans; Mitochondria; Mutation; Proto-Oncogene Proteins c-bcl-2; Rats; Thymidine Kinase; Tumor Suppressor Protein p53	2005
A novel mechanism of synergistic cytotoxicity with 5-fluorocytosine and ganciclovir in double suicide gene therapy. Cancer research, 2006, Mar-15, Volume: 66, Issue:6 Topics: Adenoviridae; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cytosine Deaminase; Deoxyguanosine; Deoxyribonucleotides; Drug Administration Schedule; Drug Synergism; Flucytosine; Fluorouracil; Ganciclovir; Genetic Therapy; Genetic Vectors; Humans; Male; Prostatic Neoplasms; Simplexvirus; Thymidine Kinase	2006
[Adenovirus-mediated double suicide gene therapy for experimental bladder carcinoma]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2006, Volume: 26, Issue:5 Topics: Adenoviridae; Animals; Cell Line; Cell Line, Tumor; Cytosine Deaminase; Defective Viruses; Female; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Thymidine Kinase; Treatment Outcome; Urinary Bladder Neoplasms	2006
[Effect of KDR recombinant adenovirus containing double suicide gene on proliferation of human stomach adneocarcinoma SCG7901 cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:1 Topics: Adenocarcinoma; Adenoviridae; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Vectors; Green Fluorescent Proteins; Humans; Neovascularization, Pathologic; Prodrugs; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach Neoplasms; Transfection; Vascular Endothelial Growth Factor Receptor-2	2007
[Killing effect of double suicide genes mediated by retroviral vector on k562 cells]. Zhongguo shi yan xue ye xue za zhi, 2007, Volume: 15, Issue:1 Topics: Cytosine Deaminase; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; K562 Cells; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Recombination, Genetic; Retroviridae	2007
[Targeted killing of colorectal tumor cells by lentiviral constructs containing CD/TK suicide genes and KDR promoter]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:5 Topics: Antimetabolites; Apoptosis; Cell Line; Cell Line, Tumor; Colorectal Neoplasms; Cytosine Deaminase; Flow Cytometry; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Vectors; Humans; Lentivirus; Promoter Regions, Genetic; Recombinant Fusion Proteins; Thymidine Kinase; Transfection; Vascular Endothelial Growth Factor Receptor-2	2007
[Preliminary effect of VEGF promoter-driven recombinant adenovirus containing double suicide genes on apoptosis of human gastric carcinoma cells]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2007, Volume: 27, Issue:8 Topics: Adenoviridae; Animals; Apoptosis; Calcium; Cell Line, Tumor; DNA; DNA, Recombinant; Dose-Response Relationship, Drug; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Humans; Microscopy, Electron; Promoter Regions, Genetic; Stomach Neoplasms; Vascular Endothelial Growth Factor A	2007
[Adenovirus-mediated double suicide gene selectively kills breast cancer MCF-7 cells in vitro]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2008, Volume: 28, Issue:6 Topics: Adenoviridae; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytosine Deaminase; Female; Flow Cytometry; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; Humans; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Thymidine Kinase; Vascular Endothelial Growth Factor A	2008
Transferrin lipoplex-mediated suicide gene therapy of oral squamous cell carcinoma in an immunocompetent murine model and mechanisms involved in the antitumoral response. Cancer gene therapy, 2009, Volume: 16, Issue:1 Topics: Animals; Antimetabolites; Antiviral Agents; Apoptosis; Carcinoma, Squamous Cell; Cholesterol; Cytokines; Fatty Acids, Monounsaturated; Female; Flucytosine; Ganciclovir; Gene Transfer Techniques; Genes, Transgenic, Suicide; Genetic Therapy; Liposomes; Lymphocytes; Mice; Mouth Neoplasms; Quaternary Ammonium Compounds; Simplexvirus; Thymidine Kinase; Transferrin; Viral Proteins	2009
[Killing effects of PWZL plasmid-mediated double suicide gene on human lens epithelium cells]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2008, Volume: 44, Issue:4 Topics: Cell Survival; Cells, Cultured; Cytosine Deaminase; Epithelial Cells; Escherichia coli; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; Lens, Crystalline; Plasmids; Thymidine Kinase; Transfection	2008
Highly efficient gene transfer to solid tumors in vivo by tumor-selective replicating retrovirus vectors. International journal of molecular medicine, 2010, Volume: 25, Issue:5 Topics: Animals; Antimetabolites; Antiviral Agents; Breast Neoplasms; Cell Line; Cytosine Deaminase; Female; Flucytosine; Ganciclovir; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms; Retroviridae; Thymidine Kinase	2010
The targeted gene (KDRP-CD/TK) therapy of breast cancer mediated by SonoVue and ultrasound irradiation in vitro. Ultrasonics, 2012, Volume: 52, Issue:1 Topics: Analysis of Variance; Breast Neoplasms; Cell Line, Tumor; Contrast Media; Cytosine Deaminase; Female; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Green Fluorescent Proteins; Humans; In Vitro Techniques; Microbubbles; Phospholipids; Prodrugs; Promoter Regions, Genetic; Sulfur Hexafluoride; Thymidine Kinase; Transfection; Tumor Cells, Cultured; Ultrasonics	2012
Selective killing of lung cancer cells using carcinoembryonic antigen promoter and double suicide genes, thymidine kinase and cytosine deaminase (pCEA-TK/CD). Cancer letters, 2012, Volume: 316, Issue:1 Topics: Apoptosis; Carcinoembryonic Antigen; Cell Cycle; Cell Line, Tumor; Cytosine Deaminase; Flucytosine; Ganciclovir; Gene Expression; Genes, Transgenic, Suicide; Genetic Therapy; Humans; Lung Neoplasms; Plasmids; Prodrugs; Promoter Regions, Genetic; Thymidine Kinase; Transfection	2012
Human amniotic fluid-derived stem cells expressing cytosine deaminase and thymidine kinase inhibits the growth of breast cancer cells in cellular and xenograft mouse models. Cancer gene therapy, 2012, Volume: 19, Issue:6 Topics: Amniotic Fluid; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chemotaxis; Cytosine Deaminase; Escherichia coli; Female; Flucytosine; Ganciclovir; Genetic Engineering; Humans; Mice; Mice, Inbred BALB C; Prodrugs; Simplexvirus; Stem Cell Transplantation; Stem Cells; Thymidine Kinase; Tumor Burden; Xenograft Model Antitumor Assays	2012
Adenovirus-mediated tissue-targeted expression of the CDglyTk gene for the treatment of breast cancer. Molecular medicine reports, 2012, Volume: 6, Issue:2 Topics: Adenoviridae; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytosine Deaminase; Female; Flow Cytometry; Flucytosine; Ganciclovir; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; Mice; Mice, Nude; Promoter Regions, Genetic; Recombinant Fusion Proteins; Thymidine Kinase; Xenograft Model Antitumor Assays	2012
Neural stem cell-based dual suicide gene delivery for metastatic brain tumors. Cancer gene therapy, 2012, Volume: 19, Issue:11 Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Brain Neoplasms; Bystander Effect; Carotid Arteries; Cell Movement; Cell Survival; Cytosine Deaminase; Flucytosine; Ganciclovir; Gene Transfer Techniques; Genes, Transgenic, Suicide; Genetic Engineering; Green Fluorescent Proteins; HEK293 Cells; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Mice; Mice, Nude; Neoplasms, Experimental; Neural Stem Cells; Prodrugs; Simplexvirus; Thymidine Kinase	2012
Intrinsic properties of tumour cells have a key impact on the bystander effect mediated by genetically engineered mesenchymal stromal cells. The journal of gene medicine, 2012, Volume: 14, Issue:12 Topics: Animals; ATP-Binding Cassette Transporters; Bystander Effect; Cell Communication; Cell Line, Tumor; Cell Survival; Cytosine Deaminase; Drug Resistance, Neoplasm; Flucytosine; Ganciclovir; Gap Junctions; Gene Expression; Gene Silencing; Genetic Vectors; Humans; Mesenchymal Stem Cells; Mice; Pentosyltransferases; Prodrugs; Retroviridae; Thymidine Kinase; Transduction, Genetic	2012
Thymidine kinase/ganciclovir and cytosine deaminase/5-fluorocytosine suicide gene therapy-induced cell apoptosis in breast cancer cells. Oncology reports, 2013, Volume: 30, Issue:3 Topics: Adenoviridae; Antimetabolites; Antiviral Agents; Apoptosis; Blotting, Western; Breast Neoplasms; Caspases; Cell Cycle; Cytosine Deaminase; Female; Flow Cytometry; Flucytosine; Ganciclovir; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; Immunoenzyme Techniques; MCF-7 Cells; Microscopy, Electron, Transmission; Prodrugs; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thymidine Kinase; Vascular Endothelial Growth Factor A	2013
Lentivirus-mediated CD/TK fusion gene transfection neural stem cell therapy for C6 glioblastoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013, Volume: 34, Issue:6 Topics: Animals; Antimetabolites; Antineoplastic Combined Chemotherapy Protocols; Antiviral Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cells, Cultured; Combined Modality Therapy; Cytosine Deaminase; Female; Flucytosine; Ganciclovir; Genetic Vectors; Glioblastoma; Lentivirus; Neural Stem Cells; Pregnancy; Rats; Rats, Wistar; Recombinant Fusion Proteins; Thymidine Kinase; Transfection; Tumor Burden	2013
Antibody-directed double suicide gene therapy targeting of MUC1- positive leukemia cells in vitro and in vivo. Current gene therapy, 2013, Volume: 13, Issue:5 Topics: Animals; Apoptosis; Cell Proliferation; Cytosine Deaminase; Disease Models, Animal; Flucytosine; Ganciclovir; Gene Targeting; Gene Transfer Techniques; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; HEK293 Cells; Humans; Jurkat Cells; K562 Cells; Lentivirus; Leukemia; Male; Mice; Mice, Nude; Mucin-1; Plasmids; Prodrugs; Thymidine Kinase; U937 Cells	2013
[Cytosine deaminase and thymidine kinase double suicide gene system driven by carcinoembryonic antigen promoter for the treatment of colorectal carcinoma xenograft in nude mice]. Zhonghua yi xue za zhi, 2013, Jul-23, Volume: 93, Issue:28 Topics: Animals; Carcinoembryonic Antigen; Colorectal Neoplasms; Cytosine Deaminase; Flucytosine; Ganciclovir; Genetic Therapy; HeLa Cells; Humans; Injections, Intralesional; Mice; Mice, Nude; Promoter Regions, Genetic; Thymidine Kinase; Transfection; Xenograft Model Antitumor Assays	2013
A dual drug sensitive L. major induces protection without lesion in C57BL/6 mice. PLoS neglected tropical diseases, 2014, Volume: 8, Issue:5 Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Female; Flucytosine; Ganciclovir; Immunoglobulin G; Leishmania major; Leishmaniasis Vaccines; Leishmaniasis, Cutaneous; Mice; Mice, Inbred C57BL; Organisms, Genetically Modified; Parasite Load	2014
Effects of an adenoviral vector containing a suicide gene fusion on growth characteristics of breast cancer cells. Molecular medicine reports, 2014, Volume: 10, Issue:6 Topics: Adenoviridae; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytosine Deaminase; Female; Flucytosine; Ganciclovir; Gene Fusion; Genes, Transgenic, Suicide; Genetic Therapy; Genetic Vectors; Humans; MCF-7 Cells; Promoter Regions, Genetic; Recombinant Fusion Proteins; Thymidine Kinase; Vascular Endothelial Growth Factor A	2014
Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. Neurosurgery, 2016, Volume: 79, Issue:3 Topics: Animals; Cytosine Deaminase; Flucytosine; Fluorouracil; Ganciclovir; Genetic Engineering; Genetic Therapy; Glioma; Humans; Neural Stem Cells; Rats; Spinal Cord Neoplasms; Stem Cell Transplantation; Thymidine Kinase; Xenograft Model Antitumor Assays	2016