fluconazole has been researched along with warfarin in 49 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.04) | 18.7374 |
1990's | 11 (22.45) | 18.2507 |
2000's | 10 (20.41) | 29.6817 |
2010's | 24 (48.98) | 24.3611 |
2020's | 3 (6.12) | 2.80 |
Authors | Studies |
---|---|
Duffy, EM; Jorgensen, WL | 1 |
Topliss, JG; Yoshida, F | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Aguilera-Venegas, B; Bloomer, WD; Chatelain, E; Ioset, JR; Kaiser, M; Lepesheva, GI; Papadopoulou, MV; Rosenzweig, HS; Wilkinson, SR | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Carey, D; Lee, HS; Tett, S | 1 |
Gibaldi, M | 1 |
Black, DJ; Celum, CL; Seaton, TL | 1 |
Rieth, H; Sauerbrey, N | 1 |
Baciewicz, AM; Baud, EB; Bokar, JA; Menke, JJ | 1 |
Crussell-Porter, LL; Ford, MA; Jaskar, DW; Rindone, JP | 1 |
Kerr, HD | 1 |
Kunze, KL; Rettie, AE; Storch, E; Trager, WF; Wienkers, LC; Wurden, CJ | 1 |
Kunze, KL; Thummel, KE; Trager, WF; Wienkers, LC | 1 |
Bauwens, JE; Black, DJ; Evans, JS; Gidal, BE; Kunze, KL; McDonnell, ND; Seaton, TL; Trager, WF; Wienkers, LC | 1 |
Kunze, KL; Trager, WF | 1 |
Ariyaratnam, S; Pemberton, M; Sloan, P; Thakker, NS; Thornhill, MH | 1 |
Das, A; Mootha, VV; Schluter, ML | 1 |
Allison, EJ; Langenberg, JN; McKinney, TJ | 1 |
Kunze, KL; Levy, RH; Neal, JM; O'Reilly, RA; Trager, WF | 1 |
Turrentine, MA | 1 |
Ditmer, D; Feldstein, AC; Krall, M; Perrin, N; Platt, R; Simon, SR; Sittig, DF; Smith, DH; Soumerai, SB; Yang, X | 1 |
Bergman, U; Bertilsson, L; Engström Hellgren, K; Helldén, A; Masquelier, M; Nilsson Remahl, I; Odar-Cederlöf, I; Ramsjö, M | 1 |
Bavisotto, LM; Canafax, DM; Combs, DL; Ellis, DJ; Irwin, I; Milner, PG | 1 |
Geng, RX; Ji, QG; Shi, Y; Zhou, CH; Zhou, XD | 1 |
Al-Ayed, AS; Hamdi, N | 1 |
Fukatsu, S; Habu, Y; Kimura, Y; Matsubara, K; Ozaki, J; Sato, E; Shida, A; Yamamoto, H; Yano, I | 1 |
Hersh, EV; Moore, PA | 1 |
Akiyoshi, T; Hakoda, R; Imaoka, A; Ohtani, H | 1 |
Cagnoli, GA; Cassina, M; Clementi, M; Di Gianantonio, E; Zuccarello, D | 1 |
Chai, D; Du, J; Guan, SX; Huang, XW; Jiang, YY; Li, DD; Sun, Y; Zhang, HY | 1 |
Cao, YB; Gu, LQ; Han, B; Jiang, YY; Li, LP; Shen, CY; Wang, XJ; Yang, QL; Yu, YQ; Zhang, JY; Zhang, LL | 1 |
de Abajo, FJ; Gaist, D; Martín-Pérez, M; Rodríguez, LAG | 1 |
de Filette, J; Michiels, V | 1 |
Brüggemann, R; Wasmann, R | 1 |
Aabenhus, RM; Hellfritzsch, M; Iversen, DB; Lind, BS; Pottegård, A; Stage, TB | 1 |
Cao, S; Ding, C; Wang, R; Xia, M; Zhu, X | 1 |
Guo, C; Guo, M; Hou, Z; Huang, Y; Li, Z; Mou, Y; Wang, X; Wang, Y; Wei, Y; Yan, Z; Zhao, D | 1 |
3 review(s) available for fluconazole and warfarin
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug interactions: Part I.
Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine | 1992 |
Three Serious Drug Interactions that Every Dentist Should Know About.
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Bradycardia; Cytochrome P-450 CYP2C9; Dental Care; Drug Interactions; Epinephrine; Fluconazole; Hemorrhage; Humans; International Normalized Ratio; Lithium; Metronidazole; Propranolol; Warfarin | 2015 |
5 trial(s) available for fluconazole and warfarin
Article | Year |
---|---|
[Interaction studies with fluconazole, a new triazole antifungal drug].
Topics: Adult; Antipyrine; Cimetidine; Clinical Trials as Topic; Contraceptives, Oral; Cyclosporins; Double-Blind Method; Drug Interactions; Female; Fluconazole; Humans; Male; Testosterone; Tolbutamide; Warfarin | 1989 |
Warfarin-fluconazole. II. A metabolically based drug interaction: in vivo studies.
Topics: Adult; Anticoagulants; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Fluconazole; Half-Life; Humans; Male; Prothrombin Time; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Warfarin | 1996 |
Kiiv, an in vivo parameter for predicting the magnitude of a drug interaction arising from competitive enzyme inhibition.
Topics: Administration, Oral; Adult; Algorithms; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cross-Over Studies; Cytochrome P-450 CYP2C9; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Kinetics; Male; Metabolic Clearance Rate; Prothrombin Time; Stereoisomerism; Time Factors; Warfarin | 2003 |
Reducing warfarin medication interactions: an interrupted time series evaluation.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Drug Interactions; Drug Prescriptions; Education, Medical, Continuing; Female; Fluconazole; Health Maintenance Organizations; Humans; Male; Medical Records Systems, Computerized; Metronidazole; Middle Aged; Sulfamethoxazole; Warfarin | 2006 |
Tecarfarin, a novel vitamin K reductase antagonist, is not affected by CYP2C9 and CYP3A4 inhibition following concomitant administration of fluconazole in healthy participants.
Topics: Administration, Oral; Adult; Aryl Hydrocarbon Hydroxylases; Benzoates; Coumarins; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Fluconazole; Humans; Male; NAD(P)H Dehydrogenase (Quinone); Warfarin | 2011 |
41 other study(ies) available for fluconazole and warfarin
Article | Year |
---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Novel 3-nitrotriazole-based amides and carbinols as bifunctional antichagasic agents.
Topics: Amides; Animals; Cell Line; Chagas Disease; Dose-Response Relationship, Drug; Methanol; Mice; Mice, Inbred BALB C; Molecular Structure; Parasitic Sensitivity Tests; Rats; Structure-Activity Relationship; Triazoles; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi | 2015 |
Drug interactions with fluconazole.
Topics: Cross-Sectional Studies; Cyclosporine; Drug Interactions; Fluconazole; Humans; Phenytoin; Theophylline; Warfarin | 1992 |
Possible potentiation of warfarin by fluconazole.
Topics: Administration, Oral; Aged; Drug Synergism; Female; Fluconazole; Humans; Warfarin | 1990 |
Fluconazole-warfarin interaction.
Topics: Adult; Drug Interactions; Epistaxis; Female; Fluconazole; Gingival Hemorrhage; Humans; Melena; Warfarin | 1994 |
Low-dose fluconazole therapy potentiates the hypoprothrombinemic response of warfarin sodium.
Topics: Aged; Aged, 80 and over; Drug Synergism; Fluconazole; Humans; Male; Middle Aged; Prothrombin; Prothrombin Time; Warfarin | 1993 |
Case report: potentiation of warfarin by fluconazole.
Topics: Aged; Drug Synergism; Female; Fluconazole; Gastrointestinal Hemorrhage; Humans; Warfarin | 1993 |
Formation of (R)-8-hydroxywarfarin in human liver microsomes. A new metabolic marker for the (S)-mephenytoin hydroxylase, P4502C19.
Topics: Aryl Hydrocarbon Hydroxylases; Biomarkers; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Humans; Hydroxylation; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Theophylline; Tranylcypromine; Warfarin | 1996 |
Warfarin-fluconazole. I. Inhibition of the human cytochrome P450-dependent metabolism of warfarin by fluconazole: in vitro studies.
Topics: Anticoagulants; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluconazole; Humans; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Warfarin | 1996 |
Warfarin-fluconazole. III. A rational approach to management of a metabolically based drug interaction.
Topics: Anticoagulants; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluconazole; Humans; Hypoglycemic Agents; Models, Biological; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tolbutamide; Warfarin | 1996 |
Treating oral candidiasis: potentially fatal.
Topics: Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Candidiasis, Oral; Drug Interactions; Erythromycin; Fluconazole; Humans; Warfarin | 1997 |
Intraocular hemorrhages due to warfarin fluconazole drug interaction in a patient with presumed Candida endophthalmitis.
Topics: Adult; Anticoagulants; Antifungal Agents; Candidiasis; Choroid Hemorrhage; Drug Interactions; Endophthalmitis; Eye Hemorrhage; Eye Infections, Fungal; Fluconazole; Humans; Male; Retinal Hemorrhage; Ultrasonography; Vitreous Hemorrhage; Warfarin | 2002 |
Spinal epidural haematoma as a result of warfarin/fluconazole drug interaction.
Topics: Adult; Aged; Anticoagulants; Antifungal Agents; Drug Interactions; Female; Fluconazole; Hematoma, Epidural, Cranial; Humans; Male; Spinal Cord Diseases; Warfarin | 2002 |
Single-dose fluconazole for vulvovaginal candidiasis: impact on prothrombin time in women taking warfarin.
Topics: Anticoagulants; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Middle Aged; Prothrombin Time; Time Factors; Warfarin | 2006 |
Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.
Topics: Alleles; Angiotensin II Type 1 Receptor Blockers; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Ataxia; Behcet Syndrome; Case-Control Studies; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Disorders of Excessive Somnolence; Dose-Response Relationship, Drug; Fatigue; Female; Fluconazole; Humans; Losartan; Middle Aged; Pharmaceutical Preparations; Phenotype; Phenytoin; Polymorphism, Genetic; Speech Intelligibility; Warfarin | 2010 |
[Synthesis and antimicrobial evaluation of coumarin-based benzotriazoles and their synergistic effects with chloromycin and fluconazole].
Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus fumigatus; Chloramphenicol; Coumarins; Drug Synergism; Fluconazole; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Methicillin-Resistant Staphylococcus aureus; Staphylococcus aureus; Triazoles | 2011 |
A new and efficient method for the synthesis of novel 3-acetyl coumarins oxadiazoles derivatives with expected biological activity.
Topics: Anti-Bacterial Agents; Antifungal Agents; Bacillus subtilis; Benzothiazoles; Biphenyl Compounds; Coumarins; Escherichia coli; Fluconazole; Free Radical Scavengers; Free Radicals; Fungi; Microbial Sensitivity Tests; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Oxadiazoles; Picrates; Salmonella typhi; Shigella flexneri; Staphylococcus aureus; Sulfonic Acids | 2014 |
Comparison of the effects of azole antifungal agents on the anticoagulant activity of warfarin.
Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Antifungal Agents; Drug Interactions; Drug Resistance; Female; Fluconazole; Humans; International Normalized Ratio; Itraconazole; Male; Metabolism, Inborn Errors; Middle Aged; Retrospective Studies; Voriconazole; Warfarin | 2014 |
In silico evaluation of warfarin-bucolome therapy.
Topics: Anticoagulants; Barbiturates; Computer Simulation; Cytochrome P-450 CYP2C9 Inhibitors; Drug Therapy, Combination; Fluconazole; Humans; Models, Biological; Warfarin | 2016 |
Human teratogens and genetic phenocopies. Understanding pathogenesis through human genes mutation.
Topics: Abnormalities, Drug-Induced; Angiotensin-Converting Enzyme Inhibitors; Animals; Female; Fetal Diseases; Fetus; Fluconazole; Humans; Isoxazoles; Leflunomide; Mutation; Mycophenolic Acid; Phenotype; Pregnancy; Teratogenesis; Teratogens; Thalidomide; Warfarin | 2017 |
Potent
Topics: Antifungal Agents; Candida albicans; Candidiasis; Coumarins; Drug Resistance, Fungal; Drug Synergism; Drug Therapy, Combination; Fluconazole; Gene Expression Regulation, Fungal; Microbial Sensitivity Tests; Oxidative Stress; Reactive Oxygen Species | 2017 |
Antifungal activity of osthol in vitro and enhancement in vivo through Eudragit S100 nanocarriers.
Topics: Administration, Oral; Animals; Antifungal Agents; Candida albicans; Candidiasis; Coumarins; Disease Models, Animal; Drug Carriers; Drug Synergism; Fluconazole; Mice; Plasma; Polymethacrylic Acids; Treatment Outcome | 2018 |
Population Impact of Drug Interactions with Warfarin: A Real-World Data Approach.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anticoagulants; Carbamazepine; Databases, Factual; Drug Interactions; Female; Fluconazole; Follow-Up Studies; Humans; International Normalized Ratio; Male; Miconazole; Middle Aged; Nystatin; Primary Health Care; Retrospective Studies; United Kingdom; Warfarin; Young Adult | 2018 |
Bleeding interaction between fluconazole and warfarin.
Topics: Aged; Anticoagulants; Antifungal Agents; Drug Interactions; Female; Fluconazole; Hematoma; Humans; Pharyngeal Diseases; Warfarin | 2018 |
A stitch in time saves nine.
Topics: Fluconazole; Hemorrhage; Humans; Warfarin | 2019 |
Antimycotic Treatment of Oral Candidiasis in Warfarin Users.
Topics: Administration, Oral; Aged; Aged, 80 and over; Anticoagulants; Antifungal Agents; Candidiasis, Oral; Drug Interactions; Female; Fluconazole; Gels; Humans; International Normalized Ratio; Male; Miconazole; Solutions; Warfarin | 2021 |
Fungal endocarditis with heart valve replacement and atrial fibrillation posing a treatment challenge: A case report.
Topics: Antifungal Agents; Atrial Fibrillation; Candida parapsilosis; Candidiasis; Caspofungin; Combined Modality Therapy; Diagnosis, Differential; Endocarditis, Non-Infective; Female; Fluconazole; Hemiplegia; Humans; Infarction, Middle Cerebral Artery; Middle Aged; Mitral Valve; Prosthesis-Related Infections; Warfarin | 2020 |
Developing Novel Coumarin-Containing Azoles Antifungal Agents by the Scaffold Merging Strategy for Treating Azole-Resistant Candidiasis.
Topics: Antifungal Agents; Azoles; Candidiasis; Coumarins; Fluconazole; Humans | 2023 |