fluconazole has been researched along with vt-1161 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Garvey, EP; Hoekstra, WJ; Moore, WR; Rafferty, SW; Schotzinger, RJ; Yates, CM | 1 |
| Garvey, EP; Hoekstra, WJ; Schotzinger, RJ; Shaver, SR; Yates, CM | 1 |
| Fidel, PL; Garvey, EP; Hoekstra, WJ; Lilly, EA; Schotzinger, RJ; Sobel, JD | 1 |
| Barker, BM; Doyle, AL; Fothergill, AW; Galgiani, JN; Garvey, EP; Hoekstra, WJ; Lewis, ER; Lewis, ML; Schotzinger, RJ; Shubitz, LF; Trinh, HT; Wiederhold, NP | 1 |
| Garvey, EP; Hoekstra, WJ; Kelly, DE; Kelly, SL; Nes, WD; Parker, JE; Price, CL; Schotzinger, RJ; Warrilow, AGS; Wiederhold, NP | 1 |
| Break, TJ; Desai, JV; Ferre, EMN; Garvey, EP; Henderson, C; Hoekstra, WJ; Lionakis, MS; Natarajan, M; Schotzinger, RJ; Siebenlist, U; Zelazny, AM | 1 |
| Brand, SR; Degenhardt, TP; Nyirjesy, P; Person, K; Schotzinger, RJ; Sobel, JD; Tavakkol, A | 1 |
| Brand, SR; Degenhardt, TP; Ghannoum, MA; Nyirjesy, P; Schotzinger, RJ; Sobel, JD | 1 |
2 trial(s) available for fluconazole and vt-1161
| Article | Year |
|---|---|
A phase 2, randomized, double-blind, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of orally administered VT-1161 in the treatment of recurrent vulvovaginal candidiasis.
Topics: 14-alpha Demethylase Inhibitors; Administration, Oral; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Double-Blind Method; Female; Fluconazole; Humans; Induction Chemotherapy; Maintenance Chemotherapy; Middle Aged; Pyridines; Recurrence; Tetrazoles; Young Adult | 2018 |
A Randomized Phase 2 Study of VT-1161 for the Treatment of Acute Vulvovaginal Candidiasis.
Topics: Administration, Oral; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Pyridines; Tetrazoles | 2021 |
6 other study(ies) available for fluconazole and vt-1161
| Article | Year |
|---|---|
Design and optimization of highly-selective fungal CYP51 inhibitors.
Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Candida albicans; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Conformation; Sterol 14-Demethylase; Structure-Activity Relationship | 2014 |
Design and optimization of highly-selective, broad spectrum fungal CYP51 inhibitors.
Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Azoles; Cytochrome P450 Family 51; Drug Design; Fungi; Humans; Molecular Docking Simulation; Mycoses; Pyridines; Tetrazoles | 2017 |
Efficacy of the clinical agent VT-1161 against fluconazole-sensitive and -resistant Candida albicans in a murine model of vaginal candidiasis.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis, Vulvovaginal; Female; Fluconazole; Mice; Pyridines; Tetrazoles; Vagina | 2015 |
Evaluation of VT-1161 for Treatment of Coccidioidomycosis in Murine Infection Models.
Topics: 14-alpha Demethylase Inhibitors; Animals; Antifungal Agents; Coccidioides; Coccidioidomycosis; Disease Models, Animal; Female; Fluconazole; Fungal Proteins; Fungemia; Half-Life; Humans; Mice; Microbial Sensitivity Tests; Pyridines; Sterol 14-Demethylase; Survival Analysis; Tetrazoles; Treatment Outcome | 2015 |
The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51.
Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyridines; Sterol 14-Demethylase; Substrate Specificity; Tetrazoles; Trichophyton; Voriconazole | 2017 |
VT-1161 protects mice against oropharyngeal candidiasis caused by fluconazole-susceptible and -resistant Candida albicans.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antifungal Agents; Candida albicans; Candida glabrata; Candidiasis, Oral; Drug Resistance, Fungal; Fluconazole; Humans; Mice; Mice, Knockout; Microbial Sensitivity Tests; Pyridines; Tetrazoles | 2018 |