Compounds > fluconazole

fluconazole and vorinostat

fluconazole has been researched along with vorinostat in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's4 (40.00)24.3611
2020's4 (40.00)2.80

Authors

AuthorsStudies
Brosch, G; Mai, A; Massa, S; Palamara, AT; Passariello, C; Rotili, D; Simonetti, G1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dong, G; Huang, Y; Li, H; Liu, N; Sheng, C; Zhang, W1
Han, G; Li, C; Li, Z; Liu, N; Sheng, C; Tu, J1
Han, G; Li, Z; Liu, N; Sheng, C; Tu, J1
Chen, X; Li, C; Liu, N; Sheng, C; Tu, J; Xu, D; Zhu, T1
Han, G; Li, C; Liu, N; Sheng, C; Tu, J1

Reviews

1 review(s) available for fluconazole and vorinostat

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for fluconazole and vorinostat

ArticleYear
Discovery of uracil-based histone deacetylase inhibitors able to reduce acquired antifungal resistance and trailing growth in Candida albicans.
    Bioorganic & medicinal chemistry letters, 2007, Mar-01, Volume: 17, Issue:5

    Topics: Antifungal Agents; Candida albicans; Drug Resistance, Fungal; Enzyme Inhibitors; Fluconazole; Histone Deacetylase Inhibitors; Hydroxamic Acids; Microbial Sensitivity Tests; Structure-Activity Relationship; Uracil

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Discovery of Janus Kinase 2 (JAK2) and Histone Deacetylase (HDAC) Dual Inhibitors as a Novel Strategy for the Combinational Treatment of Leukemia and Invasive Fungal Infections.
    Journal of medicinal chemistry, 2018, Jul-26, Volume: 61, Issue:14

    Topics: Animals; Apoptosis; Candida albicans; Cell Cycle; Cell Line, Tumor; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Invasive Fungal Infections; Janus Kinase 2; Leukemia, Myeloid, Acute; Mice

2018
Discovery of Novel Fungal Lanosterol 14α-Demethylase (CYP51)/Histone Deacetylase Dual Inhibitors to Treat Azole-Resistant Candidiasis.
    Journal of medicinal chemistry, 2020, 05-28, Volume: 63, Issue:10

    Topics: 14-alpha Demethylase Inhibitors; Animals; Azoles; Candida albicans; Candidiasis; Cytochrome P450 Family 51; Drug Discovery; Drug Resistance, Fungal; Female; Histone Deacetylase Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Mice; Mice, Inbred ICR; Sterol 14-Demethylase; Treatment Outcome

2020
Novel Carboline Fungal Histone Deacetylase (HDAC) Inhibitors for Combinational Treatment of Azole-Resistant Candidiasis.
    Journal of medicinal chemistry, 2021, 01-28, Volume: 64, Issue:2

    Topics: Animals; Azoles; Biofilms; Candida albicans; Candidiasis; Carbolines; Drug Resistance, Fungal; Drug Therapy, Combination; Female; Fluconazole; Fungal Proteins; Fungi; Histone Deacetylase Inhibitors; Humans; Liver; Membrane Transport Proteins; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests

2021
Lanosterol 14α-demethylase (CYP51)/histone deacetylase (HDAC) dual inhibitors for treatment of Candida tropicalis and Cryptococcus neoformans infections.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Candida tropicalis; Candidiasis, Cutaneous; Cryptococcosis; Cryptococcus neoformans; Cytochrome P450 Family 51; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Histone Deacetylase Inhibitors; Histone Deacetylases; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2021
Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles-resistant Candida albicans.
    European journal of medicinal chemistry, 2022, Jan-05, Volume: 227

    Topics: Animals; Antifungal Agents; Azoles; Candida albicans; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Female; Histone Deacetylase Inhibitors; Histone Deacetylases; HSP90 Heat-Shock Proteins; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2022