fluconazole and tamoxifen

fluconazole has been researched along with tamoxifen in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (6.67)29.6817
2010's21 (70.00)24.3611
2020's7 (23.33)2.80

Authors

AuthorsStudies
Chang, TK; Ensom, MH; Kiang, TK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Butler, MS; Cooper, MA; Edwards, DJ; Elliott, AG; Galappathie, S; Mahon, PJ; Palombo, EA1
Ashton, TD; Bader, CA; Boer, G; Brooks, DA; Cooper, MA; Elliott, AG; Hickey, SM; Li, J; Nation, RL; Pfeffer, FM; Plush, SE; Schmuck, C; Thomas, M; Yu, HY1
Blundell, R; Butler, MS; Cooper, MA; Fraser, JA; Furlong, E; Kappler, U; Kobe, B; Kummari, LK; Nouwens, A; Robertson, AAB; Silva, AB1
Blanchet, M; Bourguet-Kondracki, ML; Brunel, JM; Cadelis, MM; Copp, BR; Li, SA; Sue, K; Vidal, N1
Gao, F; Huang, G; Xiao, J1
Demchenko, A; Demchenko, S; Elliott, AG; Fedchenkova, Y; Lesyk, R; Suvorova, Z; Zuegg, J1
Beteck, RM; Jesumoroti, OJ; Legoabe, LJ; Patel, OPS1
Grant, G; Patel, B; Rudrawar, S; Zunk, M1
Brablíková, M; Janoušek, J; Konečná, K; Krátký, M; Maixnerová, J; Pflégr, V; Trejtnar, F; Vinšová, J1
Bourguet-Kondracki, ML; Cadelis, MM; Copp, BR; Deed, RC; Douafer, H; Li, SA; Michel Brunel, J1
Abou-Gharbia, M; Annadurai, S; Brown, JC; Butts, A; Cardenas, ME; Chabrier-Roselló, Y; Childers, WE; DiDone, L; Heitman, J; Koselny, K; Krysan, DJ; Madhani, HD; Semighini, CP; Tabroff, J; Wang, X; Wellington, M1
Kubota, R; Matsumoto, S; Wajima, T1
Chen, L; Li, M; Li, N; Qi, F; Wang, N; Zhu, L1
Bálsamo, F; Brusca, MI; Jewtuchowicz, V; Miozza, V; Muthular, M; Passero, P; Pérez, C; Villalba, MB1
Day, JN; Hai, TP; Krysan, D; Lan, NPH; Ngan, NTT; Nhat, LTH; Thwaites, GE; Van, AD; Vinh Chau, NV1
Beardsley, J; Binh, TQ; Chau, NVV; Day, JN; Geskus, R; Hope, W; Hung, LQ; Kestelyn, E; Krysan, D; Lalloo, DG; Lan, NPH; Mai, NTH; Ngan, NTT; Phu, NH; Tai, LTH; Thanh Hoang Le, N; Thwaites, GE; Trieu, PH; Tung, NLN; Van Anh, D; Van, NTT; Vi Vi, NN; White, NJ1
Day, JN; Flower, B; Ngan, NTT1

Reviews

5 review(s) available for fluconazole and tamoxifen

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Current scenario of tetrazole hybrids for antibacterial activity.
    European journal of medicinal chemistry, 2019, Dec-15, Volume: 184

    Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles

2019
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiprotozoal Agents; Drug Development; Humans; Hypoglycemic Agents; Metronidazole

2021
Treatment of Cryptococcal Meningitis: How Have We Got Here and Where are We Going?
    Drugs, 2022, Volume: 82, Issue:12

    Topics: Adult; Amphotericin B; Antifungal Agents; Fluconazole; Flucytosine; Glucocorticoids; HIV Infections; Humans; Meningitis, Cryptococcal; Sertraline; Tamoxifen

2022

Trials

1 trial(s) available for fluconazole and tamoxifen

ArticleYear
An open label randomized controlled trial of tamoxifen combined with amphotericin B and fluconazole for cryptococcal meningitis.
    eLife, 2021, 09-28, Volume: 10

    Topics: Adult; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Drug Therapy, Combination; Female; Fluconazole; Humans; Long QT Syndrome; Male; Meningitis, Cryptococcal; Tamoxifen

2021

Other Studies

24 other study(ies) available for fluconazole and tamoxifen

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:11

    Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Antibacterial Nerol Cinnamates from the Australian Plant Eremophila longifolia.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: Acyclic Monoterpenes; Anti-Bacterial Agents; Anti-Infective Agents; Australia; Cinnamates; Coumaric Acids; Eremophila Plant; Gram-Positive Bacteria; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Plant Leaves; Plants, Medicinal; Terpenes

2017
Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane.
    European journal of medicinal chemistry, 2018, Dec-05, Volume: 160

    Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cell Membrane; Dose-Response Relationship, Drug; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Norbornanes; Peptidomimetics; Structure-Activity Relationship

2018
Antifungal benzo[b]thiophene 1,1-dioxide IMPDH inhibitors exhibit pan-assay interference (PAINS) profiles.
    Bioorganic & medicinal chemistry, 2018, 11-01, Volume: 26, Issue:20

    Topics: Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Fungal Proteins; HEK293 Cells; Hep G2 Cells; Humans; IMP Dehydrogenase; Models, Molecular; Oxadiazoles; Thiophenes

2018
6-Bromoindolglyoxylamido derivatives as antimicrobial agents and antibiotic enhancers.
    Bioorganic & medicinal chemistry, 2019, 05-15, Volume: 27, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cell Line; Cell Survival; Drug Resistance, Bacterial; Erythrocytes; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Hemolysis; Humans; Indoles; Microbial Sensitivity Tests; Polyamines

2019
Synthesis, antibacterial and antifungal activity of new 3-biphenyl-3H-Imidazo[1,2-a]azepin-1-ium bromides.
    European journal of medicinal chemistry, 2020, Sep-01, Volume: 201

    Topics: Anti-Bacterial Agents; Antifungal Agents; Azepines; Bacteria; Fungi; HEK293 Cells; Hemolysis; Humans; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2020
Design, synthesis and bioactivity evaluation of novel pyrazole linked phenylthiazole derivatives in context of antibacterial activity.
    Bioorganic & medicinal chemistry letters, 2021, 05-01, Volume: 39

    Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Pyrazoles; Structure-Activity Relationship; Thiazoles

2021
Iodinated 1,2-diacylhydrazines, benzohydrazide-hydrazones and their analogues as dual antimicrobial and cytotoxic agents.
    Bioorganic & medicinal chemistry, 2021, 07-01, Volume: 41

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Cell Survival; Drug Discovery; Fungi; Hep G2 Cells; Humans; Hydrazines; Hydrazones

2021
Valorisation of the diterpene podocarpic acid - Antibiotic and antibiotic enhancing activities of polyamine conjugates.
    Bioorganic & medicinal chemistry, 2022, 06-15, Volume: 64

    Topics: Abietanes; Adjuvants, Pharmaceutic; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Escherichia coli; Mammals; Microbial Sensitivity Tests; Polyamines; Structure-Activity Relationship

2022
Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo.
    mBio, 2014, Feb-11, Volume: 5, Issue:1

    Topics: Antifungal Agents; Cryptococcus neoformans; Drug Synergism; EF Hand Motifs; Fluconazole; Fungal Proteins; Protein Binding; Selective Estrogen Receptor Modulators; Tamoxifen; Toremifene

2014
Population pharmacokinetics of ospemifene and safety evaluation of pharmacokinetic alterations caused by intrinsic and extrinsic factors
.
    International journal of clinical pharmacology and therapeutics, 2017, Volume: 55, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Area Under Curve; Clinical Trials as Topic; Computer Simulation; Cytochrome P-450 Enzyme Inhibitors; Drug Dosage Calculations; Drug Interactions; Female; Fluconazole; Humans; Kidney; Liver; Middle Aged; Models, Biological; Nonlinear Dynamics; Polypharmacy; Selective Estrogen Receptor Modulators; Tamoxifen

2017
Predicting the Effects of Different Triazole Antifungal Agents on the Pharmacokinetics of Tamoxifen.
    AAPS PharmSciTech, 2019, Jan-02, Volume: 20, Issue:1

    Topics: Antifungal Agents; Bone Density Conservation Agents; Drug Interactions; Female; Fluconazole; Forecasting; Humans; Itraconazole; Middle Aged; Models, Biological; Tamoxifen; Triazoles; Voriconazole

2019
Effects of tamoxifen on periodontal disease and Candida albicans of patients with breast cancer and other pathologies.
    Future microbiology, 2019, Volume: 14

    Topics: Antifungal Agents; Antitussive Agents; Azoles; Breast Neoplasms; Candida albicans; Estrogens; Female; Fluconazole; Humans; Immunocompromised Host; Periodontal Diseases; Periodontal Pocket; Periodontitis; Tamoxifen

2019
The combination of tamoxifen with amphotericin B, but not with fluconazole, has synergistic activity against the majority of clinical isolates of Cryptococcus neoformans.
    Mycoses, 2019, Volume: 62, Issue:9

    Topics: Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Drug Synergism; Estrogen Antagonists; Fluconazole; Humans; Meningitis, Cryptococcal; Microbial Sensitivity Tests; Tamoxifen

2019