fluconazole and tacrolimus

fluconazole has been researched along with tacrolimus in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (11.48)	18.2507
2000's	26 (42.62)	29.6817
2010's	18 (29.51)	24.3611
2020's	10 (16.39)	2.80

Authors

Authors	Studies
Chang, TK; Ensom, MH; Kiang, TK	1
Berdicevsky, I; Eads, E; Heitman, J; Horwitz, BA; Kaufman, G; Onyewu, C; Perfect, JR; Schell, WA; Ullmann, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Cannon, RD; Holmes, AR; Lamping, E; Nakamura, K; Niimi, K; Niimi, M; Ranchod, A; Tyndall, JD	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Adibzadeh, M; Friccius, H; Pawelec, G; Pohla, H; Schenk, A; Siegels-Hübenthal, P	1
Gonzalez-Pinto, I; Jain, A; Kusne, S; Mañez, R; Martin, M; Raman, D; Silverman, D; Starzl, TE; Warty, V	1
Dix, SP; Geller, RB; Lin, LS; Mullins, RE; Osowski, CL; Wingard, JR	1
Dhawan, A; Gonde, CE; Heaton, NJ; Mowat, AP; North-Lewis, PJ; Tredger, JM	1
Bartlett, ST; Burke, GW; Gruessner, RW; Stock, PG	1
Hossain, MA; Kohno, S; Maesaki, S; Marichal, P; Sanglard, D; Vanden Bossche, H	1
Hairhara, Y; Hashizume, K; Hirata, M; Ijichi, M; Ito, M; Kawarasaki, H; Kita, Y; Kubota, K; Kusaka, K; Makuuchi, M; Matsukura, A; Nakatsuka, T; Saiura, A; Sano, K; Takayama, T; Tanaka, H; Watanabe, M; Yoshino, H	1
Cardenas, ME; Cruz, MC; Del Poeta, M; Heitman, J; Perfect, JR	1
Asano, Y; Gondo, H; Okamura, C; Okamura, T; Osaki, K; Shimoda, K	1
Adamson, R; DiRenzo, T; Friedman, GS; Kaplan, B; Mathis, AS	1
Asaka, M; Chiba, K; Hashino, S; Izumiyama, K; Suzuki, S; Takahata, M	1
Blankenship, JR; Cardenas, ME; Cruz, MC; Davis, D; Del Poeta, M; Goldstein, AL; Heitman, J; McCusker, JH; Perfect, JR	1
Ishida, H; Ito, S; Shinmura, H; Tanabe, K; Toda, F; Tokumoto, T; Toma, H	1
Alvarez Grande, J; de Oña, M; Fresno, MF; Gómez, E; Herreros, M; Melón, S; Navascués, R; Tricas, L	1
Bhaloo, S; Prasad, GV	1
Boyle, GJ; Gandhi, S; Kurland, G; Law, YM; Mahnke, CB; Michaels, M; Miller, SA; Pigula, FA; Sutton, RM; Venkataramanan, R; Webber, SA	1
Cox, GM; Ganous, TM; Kingsbury, JM; McCusker, JH; Pascon, RC	1
Heitman, J; Onyewu, C; Perfect, JR; Wormley, FL	1
Akhlaghi, F; Gleeson, M; McCaughan, G; McLachlan, AJ; Nelson, A; Zahir, H	1
Heitman, J; Husain, S; Ison, M; Pruett, TL; Reedy, JL; Singh, N	1
Cappello, D; Di Mare, M; Fiamingo, P; Gagliano, M; Giuffrida, G; Macarone, M; Severino, V; Sorbello, M; Spataro, M; Veroux, M; Veroux, P; Vizcarra, D	1
Bunnachak, D; Jittikanont, S; Kanchanarattanakorn, K; Lumlertgul, D; Manoyot, A; Noppakun, K; Ophascharoensuk, V; Rojanasthien, N	1
Fukuoka, N; Houchi, H; Ishida, T; Kawazoe, H; Ohnishi, H; Takiguchi, Y; Tanaka, H	1
Aisa, Y; Ikeda, Y; Iketani, O; Mihara, A; Mori, T; Okamoto, S; Tanigawara, Y; Yamazaki, R	1
Andes, D; Heitman, J; Nett, J; Uppuluri, P	1
Abidi, MH; Ayash, LJ; Cadotte, C; Cronin, SM; Edwards, DJ; Ibrahim, RB; Jacobson, PA; Mulawa, J; Smith, DW; Uberti, JP	1
de Jonge, H; Kuypers, DR; Naesens, M; Vanrenterghem, Y	1
Costa-de-Oliveira, S; Dias, AS; Guerra, J; Pina-Vaz, C; Ricardo, E; Rodrigues, AG	1
Blair, JE; Kokseng, SL	1
Bunin, N; Goyal, RK; Grupp, SA; Han, K; Mada, SR; Pulsipher, MA; Venkataramanan, R; Wall, DA	1
Chen, X; Chen, Z; Guan, W; Guo, X; Li, J; Li, Y; Mao, X; Wang, W	1
Chen, Z; Li, H; Shi, W; Sun, S; Zhang, C	1
Faria-Ramos, I; Miranda, IM; Pina-Vaz, C; Ricardo, E; Rodrigues, AG; Silva, RM	1
Fung, HC; Peksa, GD; Schultz, K	1
Cao, C; Li, X; Liang, H; Mo, D; Sun, C; Wei, L	1
Baudet, H; Chardot, C; Debray, D; Elens, L; Girard, M; Guy-Viterbo, V; Haufroid, V; Lacaille, F; Musuamba, F; Reding, R; Wallemacq, P	1
Chen, Z; Gao, Y; Li, H; Sun, S; Zhang, C; Zhang, X	1
Jia, W; Li, C; Li, G; Liu, X; Wei, J; Zhang, H	1
Matsuda, S; Nakagita, K; Oita, A; Takada, M; Terada, Y; Terakawa, N; Wada, K	1
Averette, AF; Bahn, YS; Beom, JY; Cheong, E; Heitman, J; Hwangbo, A; Jung, JA; Kang, SH; Lee, KT; Lee, SJ; Lee, Y; Song, MC; Yoo, YJ; Yoon, YJ	1
Chen, X; He, J; Liu, H; Liu, Y; Ma, J; Yang, W; Yin, C; Yu, Y; Zhong, L; Zou, H	1
Hedvat, J; Lange, NW; Salerno, DM; Tsapepas, DS	1
Cheng, S; Du, J; Tang, M; Yin, T	1
Kaur, R; Kumar, K; Moirangthem, R	1
Asch, WS; Casal, GH; Cohen, EA; Johnston, JP; Reardon, DP	1
Bubalo, JS; Gu, TM; Le, H; Lewis, JS	1
Aoki, J; Fukuda, T; Furukawa, T; Hashimoto, H; Inamoto, Y; Ito, A; Kim, SW; Nakashima, T; Tanaka, T	1
Alghamdi, A; Darland, L; Hooper, DK; Lazear, D; Mizuno, T; Ramsey, LB; Seay, S; Varnell, CD	1
Abdorahimi, M; Ahmadikia, K; Badali, H; Gharehbolagh, SA; Khodavaisy, S; Mahmoudi, S; Meis, JF; Rezaie, S	1
Hirai, T; Ino, K; Ishibashi, M; Iwamoto, T; Shinogi, Y; Tawara, I	1

Reviews

3 review(s) available for fluconazole and tacrolimus

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Clinically significant drug-drug interaction between tacrolimus and fluconazole in stable renal transplant recipient and literature review. Journal of clinical pharmacy and therapeutics, 2020, Volume: 45, Issue:2 Topics: Administration, Intravenous; Administration, Oral; Adult; Antifungal Agents; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Transplantation; Tacrolimus	2020

Trials

3 trial(s) available for fluconazole and tacrolimus

Article	Year
Evaluation of the drug interaction between intravenous high-dose fluconazole and cyclosporine or tacrolimus in bone marrow transplant patients. Transplantation, 1996, Apr-27, Volume: 61, Issue:8 Topics: Antifungal Agents; Bone Marrow Transplantation; Cyclosporine; Drug Interactions; Fluconazole; Graft Rejection; Humans; Immunosuppressive Agents; Prospective Studies; Tacrolimus; Transplantation, Homologous	1996
Population pharmacokinetic estimation of tacrolimus apparent clearance in adult liver transplant recipients. Therapeutic drug monitoring, 2005, Volume: 27, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Aged; Algorithms; Diltiazem; Dose-Response Relationship, Drug; Drug Monitoring; Female; Fluconazole; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Prednisolone; Retrospective Studies; Tacrolimus	2005
Pharmacokinetic study of the combination of tacrolimus and fluconazole in renal transplant patients. Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2006, Volume: 89 Suppl 2 Topics: Adult; Antifungal Agents; Area Under Curve; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Postoperative Period; Tacrolimus	2006

Other Studies

55 other study(ies) available for fluconazole and tacrolimus

Article	Year
Targeting the calcineurin pathway enhances ergosterol biosynthesis inhibitors against Trichophyton mentagrophytes in vitro and in a human skin infection model. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Antifungal Agents; Calcineurin; Colony Count, Microbial; Culture Media; Cyclosporine; Drug Synergism; Drug Therapy, Combination; Ergosterol; Fluconazole; Humans; Immunosuppressive Agents; Naphthalenes; Signal Transduction; Skin; Tacrolimus; Terbinafine; Tinea; Trichophyton	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:2 Topics: Amino Acid Sequence; Animals; Antifungal Agents; ATP-Binding Cassette Transporters; Azoles; Blotting, Northern; Blotting, Southern; Candida; Candidiasis; Cell Membrane; Chromosomes, Fungal; Drug Resistance, Fungal; Endoplasmic Reticulum; Humans; Phenotype; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells. International journal of immunopharmacology, 1992, Volume: 14, Issue:5 Topics: Antifungal Agents; Cells, Cultured; Cyclosporine; Cytokines; Fluconazole; Gene Expression; Humans; Itraconazole; Ketoconazole; Lymphocytes; Miconazole; Tacrolimus	1992
Fluconazole therapy in transplant recipients receiving FK506. Transplantation, 1994, May-27, Volume: 57, Issue:10 Topics: Drug Interactions; Fluconazole; Humans; Immunocompromised Host; Mycoses; Organ Transplantation; Tacrolimus	1994
Tacrolimus (FK506) malabsorption: management with fluconazole coadministration. Transplant international : official journal of the European Society for Organ Transplantation, 1997, Volume: 10, Issue:4 Topics: Absorption; Child; Fluconazole; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Tacrolimus	1997
Suggested guidelines for the use of tacrolimus in pancreas/kidney transplantation. Clinical transplantation, 1998, Volume: 12, Issue:3 Topics: Administration, Oral; Antifungal Agents; Antiviral Agents; Drug Interactions; Drug Therapy, Combination; Fluconazole; Graft Rejection; Guidelines as Topic; Humans; Immunosuppressive Agents; Kidney Transplantation; Mycophenolic Acid; Mycoses; Pancreas Transplantation; Tacrolimus; United States; Virus Diseases	1998
Synergic effects of tactolimus and azole antifungal agents against azole-resistant Candida albican strains. The Journal of antimicrobial chemotherapy, 1998, Volume: 42, Issue:6 Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Azoles; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Synergism; Fluconazole; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, MDR; Humans; Itraconazole; Membrane Transport Proteins; Microbial Sensitivity Tests; Tacrolimus	1998
Effect of fluconazole on blood levels of tacrolimus. Transplantation proceedings, 1999, Volume: 31, Issue:7 Topics: Adolescent; Adult; Antifungal Agents; Child; Child, Preschool; Female; Fluconazole; Humans; Immunosuppressive Agents; Liver Transplantation; Living Donors; Male; Middle Aged; Tacrolimus	1999
Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Anti-Bacterial Agents; Antifungal Agents; Calcineurin; Calcineurin Inhibitors; Caspofungin; Cryptococcus neoformans; Drug Combinations; Drug Synergism; Echinocandins; Fluconazole; Humans; Immunophilins; Lipopeptides; Macrolides; Microbial Sensitivity Tests; Peptides; Peptides, Cyclic; Tacrolimus; Tacrolimus Binding Proteins	2000
Acquired Pelger-Huët anomaly in association with concomitant tacrolimus and fluconazole therapy following allogeneic bone marrow transplantation. Bone marrow transplantation, 2000, Volume: 26, Issue:11 Topics: Adult; Antifungal Agents; Bone Marrow Transplantation; Drug Interactions; Female; Fluconazole; Humans; Immunosuppressive Agents; Pelger-Huet Anomaly; Tacrolimus	2000
Sex and ethnicity may chiefly influence the interaction of fluconazole with calcineurin inhibitors. Transplantation, 2001, Apr-27, Volume: 71, Issue:8 Topics: Adult; Antifungal Agents; Black or African American; Calcineurin Inhibitors; Cyclosporine; Drug Interactions; Ethnicity; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Pancreas Transplantation; Retrospective Studies; Sex Factors; Tacrolimus; United States	2001
Cyclosporin A-induced encephalopathy after allogeneic bone marrow transplantation with prevention of graft-versus-host disease by tacrolimus. Bone marrow transplantation, 2001, Volume: 28, Issue:7 Topics: Adult; Anemia, Aplastic; Anticonvulsants; Blood-Brain Barrier; Bone Marrow Transplantation; Brain Diseases; Brain Edema; Ceftazidime; Cerebral Hemorrhage; Cyclosporine; Diagnosis, Differential; Diuretics; Endothelium, Vascular; Epilepsy, Generalized; Female; Fluconazole; Graft vs Host Disease; Headache; Humans; Immunosuppressive Agents; Intracranial Hypertension; Magnetic Resonance Imaging; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous	2001
Calcineurin is essential for survival during membrane stress in Candida albicans. The EMBO journal, 2002, Feb-15, Volume: 21, Issue:4 Topics: Antifungal Agents; Base Sequence; Blotting, Northern; Calcineurin; Candida albicans; Cyclosporine; DNA Primers; Drug Resistance, Microbial; Fluconazole; Gene Expression Regulation, Fungal; Genes, Fungal; Methyltransferases; Tacrolimus	2002
Tacrolimus trough level adjustment after administration of fluconazole to kidney recipients. Transplantation proceedings, 2002, Volume: 34, Issue:5 Topics: ABO Blood-Group System; Adult; Antifungal Agents; Area Under Curve; Blood Group Incompatibility; Body Weight; Drug Interactions; Female; Fluconazole; Histocompatibility Testing; HLA-DR Antigens; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Retrospective Studies; Tacrolimus; Transplantation, Homologous	2002
[Remission of severe disease induced by CMV and lymphoproliferative post-transplant disease after changing the immunosuppressive regime]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:6 Topics: Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infections; Epstein-Barr Virus Infections; Fluconazole; Ganciclovir; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunosuppression Therapy; Kidney Transplantation; Lymphoproliferative Disorders; Male; Middle Aged; Postoperative Complications; Tacrolimus	2002
Severe reduction in tacrolimus levels with rifampin despite multiple cytochrome P450 inhibitors: a case report. Transplantation proceedings, 2003, Volume: 35, Issue:7 Topics: Adult; Clarithromycin; Creatinine; Cytochrome P-450 Enzyme Inhibitors; Diltiazem; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Rifampin; Tacrolimus	2003
Tacrolimus dosage requirements after initiation of azole antifungal therapy in pediatric thoracic organ transplantation. Pediatric transplantation, 2003, Volume: 7, Issue:6 Topics: Analysis of Variance; Antifungal Agents; Child; Female; Fluconazole; Humans; Immunosuppressive Agents; Itraconazole; Male; Mycoses; Organ Transplantation; Retrospective Studies; Tacrolimus	2003
Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence. Microbiology (Reading, England), 2004, Volume: 150, Issue:Pt 9 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adaptation, Physiological; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Cyclosporine; Fluconazole; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Homocysteine; Hot Temperature; Melanins; Methionine; Mice; Microbial Sensitivity Tests; Mutation; RNA, Fungal; RNA, Messenger; Tacrolimus; Transcription, Genetic; Virulence; Virulence Factors	2004
The calcineurin target, Crz1, functions in azole tolerance but is not required for virulence of Candida albicans. Infection and immunity, 2004, Volume: 72, Issue:12 Topics: Animals; Antifungal Agents; Calcineurin; Candida albicans; Drug Resistance, Fungal; Fluconazole; Mice; Mice, Inbred ICR; Tacrolimus	2004
Immunotherapy with tacrolimus (FK506) does not select for resistance to calcineurin inhibitors in Candida albicans isolates from liver transplant patients. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:4 Topics: Calcineurin Inhibitors; Calcium; Candida albicans; Drug Resistance, Fungal; Fluconazole; Humans; Immunosuppressive Agents; Liver Transplantation; Serum; Tacrolimus	2006
Caspofungin in the treatment of azole-refractory esophageal candidiasis in kidney transplant recipients. Transplantation proceedings, 2006, Volume: 38, Issue:4 Topics: Adult; Aged; Antifungal Agents; Candidiasis; Candidiasis, Vulvovaginal; Caspofungin; Cyclosporine; Echinocandins; Esophageal Diseases; Female; Fluconazole; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Incidence; Kidney Transplantation; Lipopeptides; Middle Aged; Peptides, Cyclic; Postoperative Complications; Retrospective Studies; Tacrolimus; Time Factors	2006
Change of the blood concentration of tacrolimus after the switch from fluconazole to voriconazole in patients receiving allogeneic hematopoietic stem cell transplantation. Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:12 Topics: Fluconazole; Humans; Immunosuppressive Agents; Pyrimidines; Retrospective Studies; Stem Cell Transplantation; Tacrolimus; Triazoles; Voriconazole	2006
Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole. European journal of clinical pharmacology, 2008, Volume: 64, Issue:1 Topics: Antifungal Agents; Calcineurin Inhibitors; Cyclosporine; Drug Interactions; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infusions, Intravenous; Retrospective Studies; Tacrolimus	2008
Synergistic effect of calcineurin inhibitors and fluconazole against Candida albicans biofilms. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Animals; Antifungal Agents; Biofilms; Calcineurin Inhibitors; Candida albicans; Cyclosporine; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Humans; Microbial Sensitivity Tests; Rats; Tacrolimus	2008
Effect of aprepitant on intravenous tacrolimus disposition in reduced intensity hematopoietic stem cell transplantation. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2008, Volume: 14, Issue:3 Topics: Adolescent; Adult; Antiemetics; Antifungal Agents; Aprepitant; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Injections, Intravenous; Liver Function Tests; Male; Middle Aged; Morpholines; Mycoses; Retrospective Studies; Tacrolimus; Young Adult	2008
Effects of CYP3A5 and MDR1 single nucleotide polymorphisms on drug interactions between tacrolimus and fluconazole in renal allograft recipients. Pharmacogenetics and genomics, 2008, Volume: 18, Issue:10 Topics: Adult; Aged; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 CYP3A; Drug Interactions; Female; Fluconazole; Genotype; Humans; Kidney Transplantation; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Tacrolimus	2008
Ibuprofen reverts antifungal resistance on Candida albicans showing overexpression of CDR genes. FEMS yeast research, 2009, Volume: 9, Issue:4 Topics: Antifungal Agents; Azoles; Candida albicans; Candidiasis; Drug Resistance, Fungal; Drug Synergism; Enzyme Inhibitors; Fluconazole; Fungal Proteins; Gene Expression Profiling; Humans; Ibuprofen; Membrane Transport Proteins; Microbial Sensitivity Tests; Tacrolimus	2009
Successful kidney transplantation after coccidioidal meningitis. Transplant infectious disease : an official journal of the Transplantation Society, 2011, Volume: 13, Issue:3 Topics: Adult; Antifungal Agents; Coccidioides; Coccidioidomycosis; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Transplantation; Meningitis, Fungal; Tacrolimus; Transplantation Immunology; Treatment Outcome	2011
Sirolimus pharmacokinetics in early postmyeloablative pediatric blood and marrow transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013, Volume: 19, Issue:4 Topics: Adolescent; Antifungal Agents; Area Under Curve; Bone Marrow Transplantation; Child; Child, Preschool; Drug Monitoring; Female; Fluconazole; Graft vs Host Disease; Half-Life; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Myeloablative Agonists; Sirolimus; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous; Young Adult	2013
Mutations adjacent to the end of transmembrane helices 6 and 7 independently affect drug efflux capacity of yeast ABC transporter Pdr5p. Biochimica et biophysica acta, 2014, Volume: 1838, Issue:3 Topics: Antifungal Agents; Antineoplastic Agents; ATP-Binding Cassette Transporters; Biological Transport; Cell Membrane; Cycloheximide; Drug Resistance, Fungal; Fluconazole; Immunosuppressive Agents; Mutagenesis, Site-Directed; Mutation; Rhodamines; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tacrolimus	2014
A promising approach of overcoming the intrinsic resistance of Candida krusei to fluconazole (FLC)--combining tacrolimus with FLC. FEMS yeast research, 2014, Volume: 14, Issue:5 Topics: Antifungal Agents; Candida; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Microbial Sensitivity Tests; Tacrolimus; Time Factors	2014
In vivo and in vitro acquisition of resistance to voriconazole by Candida krusei. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:8 Topics: Adult; Antifungal Agents; Antineoplastic Agents; ATP-Binding Cassette Transporters; Candida; Candidiasis; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Gene Expression; Humans; Male; Mutation; Opportunistic Infections; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sterol 14-Demethylase; Tacrolimus; Voriconazole	2014
Dosing algorithm for concomitant administration of sirolimus, tacrolimus, and an azole after allogeneic hematopoietic stem cell transplantation. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2015, Volume: 21, Issue:6 Topics: Adult; Aged; Algorithms; Antifungal Agents; Azoles; Drug Dosage Calculations; Female; Fluconazole; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Mycoses; Retrospective Studies; Sirolimus; Tacrolimus; Triazoles; Voriconazole; Young Adult	2015
In vitro interactions of calcineurin inhibitors with conventional antifungal agents against the yeast form of Penicillium marneffei. Mycopathologia, 2014, Volume: 178, Issue:3-4 Topics: Antifungal Agents; Calcineurin Inhibitors; Cyclosporine; Drug Synergism; Fluconazole; Itraconazole; Microbial Sensitivity Tests; Penicillium; Tacrolimus; Yeasts	2014
Influence of donor-recipient CYP3A4/5 genotypes, age and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: a population approach. Pharmacogenomics, 2014, Volume: 15, Issue:9 Topics: Adolescent; Child; Child, Preschool; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP3A; Female; Fluconazole; Genotype; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Liver Transplantation; Male; Metabolic Clearance Rate; Retrospective Studies; Tacrolimus; Tissue Donors; Transplant Recipients	2014
Resistance reversal induced by a combination of fluconazole and tacrolimus (FK506) in Candida glabrata. Journal of medical microbiology, 2015, Volume: 64, Issue:Pt 1 Topics: Antifungal Agents; Biological Transport; Candida glabrata; Drug Resistance, Fungal; Drug Synergism; Flow Cytometry; Fluconazole; Fungal Proteins; Gene Expression Profiling; Humans; Microbial Sensitivity Tests; Real-Time Polymerase Chain Reaction; RNA, Fungal; Tacrolimus	2015
The calcineruin inhibitor cyclosporine a synergistically enhances the susceptibility of Candida albicans biofilms to fluconazole by multiple mechanisms. BMC microbiology, 2016, 06-18, Volume: 16, Issue:1 Topics: Antifungal Agents; Biofilms; Calcineurin Inhibitors; Candida albicans; Candidiasis; Cyclosporine; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Humans; Microbial Sensitivity Tests; Tacrolimus	2016
Effect of fluconazole on the pharmacokinetics of everolimus and tacrolimus in a heart transplant recipient: Case report. International journal of clinical pharmacology and therapeutics, 2018, Volume: 56, Issue:6 Topics: Antifungal Agents; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Everolimus; Fluconazole; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Polymorphism, Single Nucleotide; Tacrolimus	2018
Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:11 Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Calcineurin; Calcineurin Inhibitors; Candida albicans; Candidiasis; Cells, Cultured; Cryptococcosis; Cryptococcus neoformans; Female; Fluconazole; Immunosuppressive Agents; Male; Mice; Microbial Sensitivity Tests; Tacrolimus; Tacrolimus Binding Protein 1A	2018
Managing the significant interaction between XR tacrolimus and fluconazole in kidney transplant recipients. Clinical transplantation, 2020, Volume: 34, Issue:8 Topics: Fluconazole; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Tacrolimus; Transplant Recipients	2020
Effects of antifungal drugs on the plasma concentrations and dosage of tacrolimus in kidney transplant patients. European journal of hospital pharmacy : science and practice, 2022, Volume: 29, Issue:4 Topics: Antifungal Agents; Drug Interactions; Fluconazole; Humans; Kidney Transplantation; Retrospective Studies; Tacrolimus; Voriconazole	2022
Two Functionally Redundant FK506-Binding Proteins Regulate Multidrug Resistance Gene Expression and Govern Azole Antifungal Resistance. Antimicrobial agents and chemotherapy, 2021, 05-18, Volume: 65, Issue:6 Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Azoles; Candida glabrata; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, MDR; Humans; Tacrolimus; Tacrolimus Binding Proteins	2021
Impact of Low-Dose Fluconazole on Tacrolimus Dosing in Renal Transplant. Journal of pharmacy practice, 2022, Volume: 35, Issue:5 Topics: Antifungal Agents; Azoles; Drug-Related Side Effects and Adverse Reactions; Fluconazole; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Nystatin; Retrospective Studies; Tacrolimus	2022
Comparative effects of fluconazole, posaconazole, and isavuconazole upon tacrolimus and cyclosporine serum concentrations. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:6 Topics: Antifungal Agents; Cyclosporine; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Nitriles; Pyridines; Retrospective Studies; Tacrolimus; Triazoles	2022
Differences in kinetics of tacrolimus concentration after letermovir discontinuation by type of concomitant azole antifungal. International journal of hematology, 2022, Volume: 115, Issue:2 Topics: Acetates; Antifungal Agents; Female; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Quinazolines; Tacrolimus; Voriconazole	2022
Tacrolimus pharmacokinetics are influenced by CYP3A5, age, and concomitant fluconazole in pediatric kidney transplant patients. Clinical and translational science, 2023, Volume: 16, Issue:10 Topics: Child; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Fluconazole; Genotype; Humans; Immunosuppressive Agents; Kidney Transplantation; Polymorphism, Single Nucleotide; Tacrolimus	2023
In vitro combination of antifungal drugs with tacrolimus (FK506) holds promise against clinical Candida species, including Candida auris. Medical mycology, 2023, Jul-06, Volume: 61, Issue:7 Topics: Anidulafungin; Animals; Antifungal Agents; Candida; Candida auris; Candida glabrata; Candida parapsilosis; Caspofungin; Echinocandins; Fluconazole; Itraconazole; Microbial Sensitivity Tests; Tacrolimus	2023
Drug interactions of tacrolimus with letermovir and azole antifungals following hematopoietic stem cell transplantation: A retrospective observational analysis. Pharmacology research & perspectives, 2023, Volume: 11, Issue:4 Topics: Adult; Antifungal Agents; Azoles; Drug Interactions; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Retrospective Studies; Tacrolimus	2023