fluconazole and sertraline

fluconazole has been researched along with sertraline in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (5.88)29.6817
2010's12 (70.59)24.3611
2020's4 (23.53)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Ji, C; Li, J; Li, W; Liu, N; Sheng, C; Tu, J; Yang, W; Yun, Z1
Atkinson, AC; Bogacka, B; Johnson, PJ; Patan, M; Youdim, KA1
Lin, X; Sachs, MS; Wang, L; Wu, C; Zhai, B1
Abassi, M; Boulware, DR; Lofgren, S; Rhein, J1
Campos, RS; Cavalcanti, BC; Costa Silva, RA; da Cruz Fonseca, SG; da Silva Gaspar, B; da Silva, AR; da Silva, CR; de Andrade Neto, JB; de Lucena, DF; de Moraes, MO; do Nascimento, FBSA; Gaspar, DM; Grangeiro, TB; Josino, MAA; Nobre Júnior, HV; Sampaio, LS1
Boulware, DR; Meya, DB; Rajasingham, R1
Abassi, M; Alhadab, AA; Boulware, DR; Brundage, RC; Meya, DB; Musubire, A; Nicol, MR; Rhein, J; Tugume, L; Williams, DA1
Bangdiwala, AS; Boulware, DR; Hullsiek, KH; Kirumira, P; Meya, DB; Nalintya, E; Naluyima, R; Namanda, S; Nikweri, Y; Rajasingham, R; Rutakingirwa, MK; Skipper, CP; Turya, F1
abuRokba, W; Alkhalifa, BA; Bulatova, NR; Darwish, RM1
Day, JN; Flower, B; Ngan, NTT1

Reviews

3 review(s) available for fluconazole and sertraline

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Recent advances in AIDS-related cryptococcal meningitis treatment with an emphasis on resource limited settings.
    Expert review of anti-infective therapy, 2017, Volume: 15, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-HIV Agents; Antifungal Agents; Antigens, Fungal; Asymptomatic Diseases; Cost-Benefit Analysis; Cryptococcus neoformans; Developing Countries; Drug Administration Schedule; Fluconazole; Humans; Mass Screening; Meningitis, Cryptococcal; Sertraline

2017
Treatment of Cryptococcal Meningitis: How Have We Got Here and Where are We Going?
    Drugs, 2022, Volume: 82, Issue:12

    Topics: Adult; Amphotericin B; Antifungal Agents; Fluconazole; Flucytosine; Glucocorticoids; HIV Infections; Humans; Meningitis, Cryptococcal; Sertraline; Tamoxifen

2022

Trials

1 trial(s) available for fluconazole and sertraline

ArticleYear
Adjunctive sertraline for asymptomatic cryptococcal antigenemia: A randomized clinical trial.
    Medical mycology, 2020, Nov-10, Volume: 58, Issue:8

    Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Antigens, Fungal; Asymptomatic Infections; Cryptococcosis; Cryptococcus; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluconazole; Humans; Male; Meningitis, Cryptococcal; Serotonin Syndrome; Sertraline

2020

Other Studies

13 other study(ies) available for fluconazole and sertraline

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery of Novel Sertraline Derivatives as Potent Anti-
    Journal of medicinal chemistry, 2022, 05-12, Volume: 65, Issue:9

    Topics: Antidepressive Agents; Antifungal Agents; Cryptococcus; Cryptococcus neoformans; Humans; Meningitis, Cryptococcal; Microbial Sensitivity Tests; Sertraline

2022
Potential application of D-optimal designs in the efficient investigation of cytochrome P450 inhibition kinetic models.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:7

    Topics: Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6 Inhibitors; Fluconazole; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Nonlinear Dynamics; Research Design; Sertraline

2010
The antidepressant sertraline provides a promising therapeutic option for neurotropic cryptococcal infections.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:7

    Topics: Animals; Antidepressive Agents; Cryptococcosis; Cryptococcus neoformans; Female; Fluconazole; Mice; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Sertraline

2012
In vitro anti-Candida activity of selective serotonin reuptake inhibitors against fluconazole-resistant strains and their activity against biofilm-forming isolates.
    Microbial pathogenesis, 2017, Volume: 107

    Topics: Animals; Antifungal Agents; Apoptosis; Biofilms; Candida; Cell Count; Cell Death; Cell Line; Cell Proliferation; DNA Damage; DNA, Fungal; Drug Resistance, Fungal; Fibroblasts; Flow Cytometry; Fluconazole; In Vitro Techniques; Membrane Potentials; Mice; Microbial Sensitivity Tests; Microbial Viability; Mitochondrial Membranes; Paroxetine; Plasma; Selective Serotonin Reuptake Inhibitors; Sertraline

2017
Are fluconazole or sertraline dose adjustments necessary with concomitant rifampin?
    HIV medicine, 2018, Volume: 19, Issue:6

    Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antibiotics, Antitubercular; Antifungal Agents; Dose-Response Relationship, Drug; Drug Interactions; Fluconazole; HIV Infections; Humans; Mycoses; Rifampin; Sertraline; Tuberculosis

2018
Pharmacokinetics-pharmacodynamics of sertraline as an antifungal in HIV-infected Ugandans with cryptococcal meningitis.
    Journal of pharmacokinetics and pharmacodynamics, 2019, Volume: 46, Issue:6

    Topics: Adult; Amphotericin B; Antifungal Agents; Brain; Cerebrospinal Fluid; Female; Fluconazole; HIV Infections; Humans; Male; Meningitis, Cryptococcal; Pilot Projects; Sertraline; Uganda

2019
Serotonin reuptake inhibitors effect on fluconazole activity against resistant Candida glabrata strains.
    Journal of global antimicrobial resistance, 2022, Volume: 29

    Topics: Antifungal Agents; Candida glabrata; Drug Resistance, Fungal; Fluconazole; Microbial Sensitivity Tests; Selective Serotonin Reuptake Inhibitors; Sertraline

2022