Compounds > fluconazole

fluconazole and ritonavir

fluconazole has been researched along with ritonavir in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (5.56)	18.2507
2000's	5 (27.78)	29.6817
2010's	11 (61.11)	24.3611
2020's	1 (5.56)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Cao, G; Cato, A; Cavanaugh, J; Granneman, R; Hsu, A; Leonard, J	1
Beijnen, JH; Burger, DM; Crommentuyn, KM; Hoetelmans, RM; Koks, CH; Koopmans, PP; Mathôt, RA; Meenhorst, PL; Mulder, JW	1
Cuadrado, JM; Jover, F; Martínez-Baltanás, A; Roig, P	1
Bonora, S; Calcagno, A; D'Avolio, A; Di Perri, G; Garazzino, S; Tettoni, M	1
Cameron, DW; Elgadi, M; la Porte, CJ; Sabo, JP	1
Maguire, JD; St Clair, K	1
Gouda, H; Handa, K; Hirono, S; Nakagome, I; Yamaotsu, N	1
George, PE; Mercedes, R; Nabukeera-Barungi, N; Otto, SBJ	1

Reviews

1 review(s) available for fluconazole and ritonavir

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

3 trial(s) available for fluconazole and ritonavir

Article	Year
Evaluation of the effect of fluconazole on the pharmacokinetics of ritonavir. Drug metabolism and disposition: the biological fate of chemicals, 1997, Volume: 25, Issue:9 Topics: Adult; Antifungal Agents; Area Under Curve; Cross-Over Studies; Drug Interactions; Female; Fluconazole; HIV Protease Inhibitors; Humans; Male; Metabolic Clearance Rate; Ritonavir	1997
The effect of fluconazole on ritonavir and saquinavir pharmacokinetics in HIV-1-infected individuals. British journal of clinical pharmacology, 2001, Volume: 51, Issue:6 Topics: Administration, Oral; Adult; Anti-HIV Agents; Antifungal Agents; Area Under Curve; Biological Availability; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Fluconazole; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Ritonavir; Saquinavir; Time Factors	2001
Interaction studies of tipranavir-ritonavir with clarithromycin, fluconazole, and rifabutin in healthy volunteers. Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:1 Topics: Adolescent; Adult; Anti-HIV Agents; Clarithromycin; Drug Interactions; Female; Fluconazole; HIV Protease Inhibitors; Humans; Male; Middle Aged; Pyridines; Pyrones; Rifabutin; Ritonavir; Sulfonamides	2009

Other Studies

14 other study(ies) available for fluconazole and ritonavir

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
[Meningeal cryptococcosis as a sign of immune reconstitution syndrome]. Enfermedades infecciosas y microbiologia clinica, 2005, Volume: 23, Issue:4 Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Anti-HIV Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Fluconazole; Flucytosine; HIV Infections; Humans; Immunologic Memory; Lamivudine; Lopinavir; Male; Meningitis, Cryptococcal; Pyrimidinones; Recurrence; Ritonavir; Syndrome; T-Lymphocyte Subsets; Zidovudine	2005
Ritonavir-dependent fluconazole boosting of nelfinavir: a report of three cases. The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:2 Topics: Adult; Antifungal Agents; Drug Synergism; Drug Therapy, Combination; Fluconazole; HIV Infections; HIV Protease Inhibitors; Humans; Male; Middle Aged; Nelfinavir; Ritonavir	2006
Role of fluconazole in a case of rapid onset ritonavir and inhaled fluticasone-associated secondary adrenal insufficiency. International journal of STD & AIDS, 2012, Volume: 23, Issue:5 Topics: Adrenal Insufficiency; Androstadienes; Anti-HIV Agents; Anti-Inflammatory Agents; Bronchitis; Drug Interactions; Fluconazole; Fluticasone; HIV Infections; Humans; Male; Middle Aged; Ritonavir	2012
Three-dimensional quantitative structure-activity relationship analysis of inhibitors of human and rat cytochrome P4503A enzymes. Drug metabolism and pharmacokinetics, 2013, Volume: 28, Issue:4 Topics: Animals; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Fluconazole; Fluvoxamine; Humans; Inhibitory Concentration 50; Ligands; Models, Molecular; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Rats; Ritonavir; Saquinavir	2013
Cryptococcal meningitis and immune reconstitution inflammatory syndrome in a pediatric patient with HIV after switching to second line antiretroviral therapy: a case report. BMC infectious diseases, 2020, Jan-21, Volume: 20, Issue:1 Topics: AIDS-Related Opportunistic Infections; Alkynes; Anti-HIV Agents; Antifungal Agents; Antigens, Fungal; Benzoxazines; Child; Cryptococcus neoformans; Cyclopropanes; Dideoxynucleosides; Drug Combinations; Female; Fluconazole; HIV; Humans; Immune Reconstitution Inflammatory Syndrome; Lamivudine; Lopinavir; Meningitis, Cryptococcal; Ritonavir; Treatment Outcome; Viral Load; Zidovudine	2020