fluconazole and rifampin

fluconazole has been researched along with rifampin in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (1.43)	18.7374
1990's	11 (15.71)	18.2507
2000's	14 (20.00)	29.6817
2010's	33 (47.14)	24.3611
2020's	11 (15.71)	2.80

Authors

Authors	Studies
Boykin, DW; Franzblau, SG; Kim, S; Perfect, JR; Schell, WA; Stephens, CE; Tanious, F; Wilson, WD	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL	1
Abbasoglu, U; Aki-Sener, E; Ertan, T; Kaynak, F; Ozkan, S; Temiz-Arpaci, O; Yalcin, I; Yildiz, I	1
Aki, E; Alper-Hayta, S; Arisoy, M; Kaynak, F; Ozkan, S; Temiz-Arpaci, O; Yildiz, I	1
Lombardo, F; Obach, RS; Waters, NJ	1
Aki, E; Bolelli, K; Ertan, T; Kaynak, F; Ozkan, S; Tekiner-Gulbas, B; Temiz-Arpaci, O; Yalcin, I; Yildiz, I	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chovatia, PT; Parekh, HH; Pathak, RB	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Dufková, I; Hrabálek, A; Karabanovich, G; Klimešová, V; Němeček, J; Pávek, P; Roh, J; Smutný, T; Stolaříková, J; Vávrová, K; Vejsová, M; Vicherek, P	1
Bharate, SS; Vishwakarma, RA	1
Akkewar, DM; Bhaskar, K; Guguloth, V; Konda, S; Munaganti, RK; Nagarapu, L; Raparthi, S	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Carazo, A; Drechslerová, M; Hrušková, ZR; Hyrsova, L; Kuneš, J; Nova, A; Pavek, P; Pour, M; Smutny, T; Špulák, M	1
Carazo, A; Hrabálek, A; Karabanovich, G; Klimešová, V; Konečná, K; Němeček, J; Pávek, P; Pavliš, O; Roh, J; Stolaříková, J; Valášková, L; Vávrová, K	1
Benková, M; Hrabálek, A; Karabanovich, G; Kavková, V; Klimešová, V; Konečná, K; Macháček, M; Němeček, J; Roh, J; Soukup, O; Stolaříková, J; Sychra, P; Vávrová, K	1
Ashok, D; Goud, GL; Manga, V; Ramesh, S; Reddy, VP; Saikrishna, B; Sriram, D; Yogeeswari, P	1
Gao, F; Huang, G; Wang, T; Xiao, J	1
Dixit, PP; Haval, KP; Haval, NB; Kasare, SL; Khedkar, VM; Patil, PS; Rekha, EM; Sriram, D	1
Denning, DW; Graybill, JR; Hanson, LH; Pappagianis, D; Rinaldi, MG; Sharkey, PK; Stevens, DA; Tucker, RM	1
Gibaldi, M	2
Apseloff, G; Gardner, MJ; Gerber, N; Henry, EB; Hilligoss, DM; Inskeep, PB; Lazar, JD	1
Coker, RJ; Harris, JR; Parkin, J; Pinching, AJ; Tomlinson, DR	1
Abruzzo, GK; Fromtling, RA; Giltinan, DM; Turnbull, TA	1
Agostino, A; D'Amore, F; Narduzzi, C; Santoro, AM	1
Crowe, HM; Nicolau, DP; Nightingale, CH; Quintiliani, R	1
Berning, SE; Brudney, KF; Burman, WJ; Gerena, GT; McGuinness, ME; Miranda-Massari, JR; Nitta, AT; Peloquin, CA	1
Jaruratanasirikul, S; Kleepkaew, A	1
Allavena, C; Bani-Sadr, F; Chiffoleau, A; Hoff, J; Raffi, F	1
Cahn, P; Canteros, C; Córdoba, S; Davel, G; Guelfand, L; Hochenfellner, F; Kaufman, S; Rodero, L	1
Bowersox, J	1
Bhaloo, S; Prasad, GV	1
Panomvana Na Ayudhya, D; Tansuphaswadikul, S; Thanompuangseree, N	1
Arayawichanont, A; Chotmongkol, V; Sawanyawisuth, K; Thavornpitak, Y	1
Bai, XQ; Deng, SJ; Li, R; Liang, QF; Luo, SY; Sun, XG; Wang, ZQ	1
Parekh, A; Prakash, J; Singh, RG; Tilak, R; Usha, U; Wani, IA	1
Gallo, A; Hurwitz, M; Hwang, C; Mojtahed, A; Whitney, J	1
Chabert, J; Daali, Y; Dayer, P; Déglon, J; Desmeules, J; Rebsamen, M; Samer, C; Staub, C; Thomas, A	1
Benne, MS; Greupink, R; Huisman, MT; Russel, FG; Schreurs, M	1
Buchbjerg, JK; Chen, G; Højer, AM; Lee, R; Serenko, M; Zhao, Z	1
Gribakina, OG; Kolyvanov, GB; Novitskaia, IaG; Seredenin, SB; Smirnov, VV; Zherdev, VP	1
Chen, X; Gao, R; Pang, X; Zhang, Y; Zhong, D; Zhong, K	1
Fraczkiewicz, G; Shi, JG; Williams, WV; Yeleswaram, S	1
Dunn, AL; Levy, RA; Reed, T; Stewart, C	1
Dymond, AW; Huang, Y; Lisbon, E; Mariani, G; Martin, P; Mathews, D; Severin, P; So, K	1
Bae, SH; Han, S; Park, GJ; Park, MH; Park, WS; Shin, SH; Shin, YG; Yim, DS	1
Boulware, DR; Meya, DB; Rajasingham, R	1
Daali, Y; Desmeules, JA; Marsousi, N; Rudaz, S	1
Aluri, J; Boyd, P; Chang, MK; Ferry, J; Lai, WG; Nomoto, M; Rege, B; Schuck, E; Siu, YA; Yasuda, S; Zamora, CA	1
Aouthmany, S; Cooper, AM; Rega, PP; Shah, K	1
Arif, S; Bishawi, M; Maskarinec, SA; Milano, C; Miller, RA; Mourad, A	1
Fan, B; Ke, A; Le, K; Prakash, C; Yang, H	1
Aman, AT; Ambara, A; Annisa, L; Darma, S; Nuryastuti, T; Wibawa, T	1
Cohen-Rabbie, S; Freshwater, T; Jain, L; Schalkwijk, S; Tomkinson, H; Vishwanathan, K; Wild, M; Xu, S; Zhou, D; Zhou, L	1
Connell, CA; Dowty, ME; Le, VH; Malhotra, BK; O'Gorman, MT; Tatulych, S; Tripathy, S; Valdez, H; Wang, X; Winton, JA; Wouters, A; Yin, N	1
Blank, A; Burhenne, J; Elbe, A; Foerster, KI; Haefeli, WE; Mikus, G; Rose, P	1
Allen, L; Bartash, R; Cowman, K; Fauvel, D; Guo, Y; Minamoto, GY; Nnani, DU; Patel, S; Vukelic, S	1
Beers, JL; Edginton, AN; Jackson, KD; Yeung, CHT	1
Madke, B; Yadav, N	1
Al-Obaidi, I; Batchelor, H; Hoerauf, A; Krome, AK; Kuesel, AC; Opoku, NO; Pfarr, KM; Vaillant, M	1

Reviews

7 review(s) available for fluconazole and rifampin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Antibacterial activity study of 1,2,4-triazole derivatives. European journal of medicinal chemistry, 2019, Jul-01, Volume: 173 Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Triazoles	2019
Drug interactions: Part I. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:5 Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine	1992
Drug interactions: part II. The Annals of pharmacotherapy, 1992, Volume: 26, Issue:6 Topics: Amiodarone; Biological Availability; Dapsone; Didanosine; Drug Interactions; Fluconazole; Food; Humans; Intestinal Absorption; Ketoconazole; Pharmaceutical Preparations; Rifampin	1992
[Sarcoidosis with pulmonary abscess caused by emerging microorganisms]. La Clinica terapeutica, 1995, Volume: 146, Issue:5 Topics: Bronchoalveolar Lavage Fluid; Ceftazidime; Fluconazole; Humans; Lung Abscess; Male; Middle Aged; Mycetoma; Radiography, Thoracic; Rifampin; Sarcoidosis; Tomography, X-Ray Computed	1995
Killer amoebas: Primary amoebic meningoencephalitis in a changing climate. JAAPA : official journal of the American Academy of Physician Assistants, 2019, Volume: 32, Issue:6 Topics: Amebicides; Aminoglycosides; Amphotericin B; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antiparasitic Agents; Azithromycin; Central Nervous System Protozoal Infections; Climate Change; Dexamethasone; Early Diagnosis; Early Medical Intervention; Fluconazole; Geography; Glucocorticoids; Humans; Hypothermia, Induced; Macrolides; Naegleria fowleri; Phosphorylcholine; Rifampin; United States; Ventriculostomy	2019
The pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label use. Parasites & vectors, 2023, Oct-31, Volume: 16, Issue:1 Topics: Anti-Infective Agents; Doxycycline; Drug Combinations; Fluconazole; Humans; Ivermectin; Neglected Diseases; Off-Label Use; Rifampin	2023

Trials

9 trial(s) available for fluconazole and rifampin

Article	Year
Induction of fluconazole metabolism by rifampin: in vivo study in humans. Journal of clinical pharmacology, 1991, Volume: 31, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Drug Administration Schedule; Fluconazole; Humans; Hydrocortisone; Male; Middle Aged; Rifampin	1991
Low antituberculosis drug concentrations in patients with AIDS. The Annals of pharmacotherapy, 1996, Volume: 30, Issue:9 Topics: Adult; Anti-HIV Agents; Antifungal Agents; Antitubercular Agents; Drug Interactions; Female; Fluconazole; HIV Infections; Humans; Male; Middle Aged; Prospective Studies; Pyrazinamide; Rifampin; Tuberculosis, Pulmonary; Zidovudine	1996
Lack of effect of fluconazole on the pharmacokinetics of rifampicin in AIDS patients. The Journal of antimicrobial chemotherapy, 1996, Volume: 38, Issue:5 Topics: Adult; AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antifungal Agents; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Male; Meningitis, Cryptococcal; Middle Aged; Rifampin	1996
Effect of rifampicin on the pharmacokinetics of fluconazole in patients with AIDS. Clinical pharmacokinetics, 2004, Volume: 43, Issue:11 Topics: Acquired Immunodeficiency Syndrome; Adult; Antibiotics, Antitubercular; Antifungal Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cryptococcus neoformans; Drug Interactions; Female; Fluconazole; Half-Life; Humans; Male; Meningitis, Cryptococcal; Middle Aged; Rifampin; Spectrophotometry, Ultraviolet; Tuberculosis	2004
Initial treatment of cryptococcal meningitis in AIDS. The Southeast Asian journal of tropical medicine and public health, 2005, Volume: 36, Issue:1 Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Enzyme Inhibitors; Female; Fluconazole; Humans; Male; Meningitis, Cryptococcal; Prospective Studies; Rifampin	2005
Pharmacokinetic drug interactions involving vortioxetine (Lu AA21004), a multimodal antidepressant. Clinical drug investigation, 2013, Volume: 33, Issue:10 Topics: Adolescent; Adult; Antidepressive Agents; Antifungal Agents; Bupropion; Cohort Studies; Contraceptives, Oral, Hormonal; Cross-Over Studies; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Female; Fluconazole; Humans; Ketoconazole; Male; Middle Aged; Omeprazole; Piperazines; Rifampin; Single-Blind Method; Sulfides; Vortioxetine; Young Adult	2013
Effects of cytochrome P450 (CYP3A4 and CYP2C19) inhibition and induction on the exposure of selumetinib, a MEK1/2 inhibitor, in healthy subjects: results from two clinical trials. European journal of clinical pharmacology, 2017, Volume: 73, Issue:2 Topics: Adolescent; Adult; Benzimidazoles; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inducers; Female; Fluconazole; Healthy Volunteers; Humans; Itraconazole; Male; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinase 2; Rifampin; Young Adult	2017
Drug-drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer. Drug design, development and therapy, 2017, Volume: 11 Topics: Adult; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluconazole; Healthy Volunteers; Humans; Male; Middle Aged; Omeprazole; Rifampin; Young Adult	2017
Pharmacokinetic/pharmacodynamic drug-drug interactions of avatrombopag when coadministered with dual or selective CYP2C9 and CYP3A interacting drugs. British journal of clinical pharmacology, 2018, Volume: 84, Issue:5 Topics: Adolescent; Adult; Cytochrome P-450 CYP2C9 Inducers; Cytochrome P-450 CYP2C9 Inhibitors; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Fluconazole; Healthy Volunteers; Humans; Itraconazole; Male; Middle Aged; Platelet Count; Receptors, Thrombopoietin; Rifampin; Thiazoles; Thiophenes; Young Adult	2018

Other Studies

54 other study(ies) available for fluconazole and rifampin

Article	Year
Diguanidino and "reversed" diamidino 2,5-diarylfurans as antimicrobial agents. Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11 Topics: Amidines; Aminopyridines; Anti-Bacterial Agents; Antifungal Agents; DNA; Furans; Mycobacterium tuberculosis; Structure-Activity Relationship	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:3 Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase	2007
Synthesis and biological evaluation of new N-(2-hydroxy-4(or 5)-nitro/aminophenyl)benzamides and phenylacetamides as antimicrobial agents. Bioorganic & medicinal chemistry, 2007, Mar-01, Volume: 15, Issue:5 Topics: Anti-Bacterial Agents; Antifungal Agents; Benzamides; Microbial Sensitivity Tests; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship	2007
Synthesis, antimicrobial activity, pharmacophore analysis of some new 2-(substitutedphenyl/benzyl)-5-[(2-benzofuryl)carboxamido]benzoxazoles. European journal of medicinal chemistry, 2008, Volume: 43, Issue:11 Topics: Amides; Anti-Bacterial Agents; Benzofurans; Benzoxazoles; Microbial Viability; Molecular Structure; Structure-Activity Relationship	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents. European journal of medicinal chemistry, 2009, Volume: 44, Issue:2 Topics: Anti-Infective Agents; Bacteria; Benzoxazoles; Candida albicans; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Quantitative Structure-Activity Relationship	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Synthesis, antitubercular and antimicrobial evaluation of 3-(4-chlorophenyl)-4-substituted pyrazole derivatives. Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15 Topics: Anti-Infective Agents; Antitubercular Agents; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazoles; Structure-Activity Relationship	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
1-Substituted-5-[(3,5-dinitrobenzyl)sulfanyl]-1H-tetrazoles and their isosteric analogs: A new class of selective antitubercular agents active against drug-susceptible and multidrug-resistant mycobacteria. European journal of medicinal chemistry, 2014, Jul-23, Volume: 82 Topics: Antineoplastic Agents; Antitubercular Agents; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Screening Assays, Antitumor; HeLa Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Nitrobenzenes; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured	2014
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics	2015
Synthesis and antimicrobial activity of novel benzoxazine sulfonamide derivatives. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Anti-Bacterial Agents; Antifungal Agents; Benzoxazines; Dose-Response Relationship, Drug; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Sulfonamides	2015
2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists. Journal of medicinal chemistry, 2016, 05-26, Volume: 59, Issue:10 Topics: Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hep G2 Cells; Hepatocytes; Humans; Models, Molecular; Molecular Structure; Quinazolines; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship	2016
S-substituted 3,5-dinitrophenyl 1,3,4-oxadiazole-2-thiols and tetrazole-5-thiols as highly efficient antitubercular agents. European journal of medicinal chemistry, 2017, Jan-27, Volume: 126 Topics: Antifungal Agents; Antitubercular Agents; Drug Design; Drug Resistance; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Oxadiazoles; Structure-Activity Relationship; Sulfhydryl Compounds; Tetrazoles	2017
Structure-activity relationship studies on 3,5-dinitrophenyl tetrazoles as antitubercular agents. European journal of medicinal chemistry, 2017, Apr-21, Volume: 130 Topics: Antitubercular Agents; Drug Resistance, Multiple; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Species Specificity; Structure-Activity Relationship; Tetrazoles	2017
Design, synthesis, molecular-docking and antimycobacterial evaluation of some novel 1,2,3-triazolyl xanthenones. MedChemComm, 2017, Mar-01, Volume: 8, Issue:3 Topics:	2017
Novel isoniazid embedded triazole derivatives: Synthesis, antitubercular and antimicrobial activity evaluation. Bioorganic & medicinal chemistry letters, 2020, 10-01, Volume: 30, Issue:19 Topics: Animals; Antifungal Agents; Antitubercular Agents; Aspergillus niger; Bacterial Proteins; Drug Design; Gram-Negative Bacteria; Isoniazid; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxidoreductases; Protein Binding; RAW 264.7 Cells; Triazoles	2020
Interaction of azoles with rifampin, phenytoin, and carbamazepine: in vitro and clinical observations. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 14, Issue:1 Topics: Adult; Aged; Antifungal Agents; Azoles; Carbamazepine; Coccidioides; Cryptococcus neoformans; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Malassezia; Male; Middle Aged; Mycoses; Phenytoin; Rifampin	1992
Interaction between fluconazole and rifampicin. BMJ (Clinical research ed.), 1990, Oct-06, Volume: 301, Issue:6755 Topics: Acquired Immunodeficiency Syndrome; Adult; Cryptococcosis; Drug Interactions; Fluconazole; Humans; Male; Meningitis; Rifampin	1990
Effects of bifonazole, fluconazole, itraconazole, and terbinafine on the chemiluminescence response of immune cells. The Journal of antimicrobial chemotherapy, 1987, Volume: 20, Issue:1 Topics: Animals; Antifungal Agents; Cell Survival; Centrifugation; Fluconazole; Imidazoles; In Vitro Techniques; Itraconazole; Ketoconazole; Luminescent Measurements; Luminol; Mice; Mice, Inbred BALB C; Naphthalenes; Phagocytes; Rabbits; Rifampin; Spleen; Terbinafine; Triazoles	1987
Rifampin-fluconazole interaction in critically ill patients. The Annals of pharmacotherapy, 1995, Volume: 29, Issue:10 Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Biological Availability; Critical Illness; Drug Interactions; Fluconazole; Humans; Intensive Care Units; Male; Middle Aged; Rifampin	1995
[Severe hypercalcemia in a patient treated with fluconazole and rifampicin]. Presse medicale (Paris, France : 1983), 1998, May-16, Volume: 27, Issue:18 Topics: Adult; AIDS-Related Opportunistic Infections; Antibiotics, Antitubercular; Antifungal Agents; Female; Fluconazole; Humans; Hypercalcemia; Pneumonia, Pneumocystis; Rifampin; Tuberculosis, Pulmonary	1998
In vitro susceptibility studies of Cryptococcus neoformans isolated from patients with no clinical response to amphotericin B therapy. The Journal of antimicrobial chemotherapy, 2000, Volume: 45, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Drug Interactions; Drug Resistance, Microbial; Fluconazole; Flucytosine; Humans; Leprostatic Agents; Rifampin; Time Factors	2000
CPCRA researchers present OI studies at Vancouver. NIAID AIDS agenda, 1996 Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Candidiasis; Child; Clarithromycin; Clinical Trials as Topic; DNA, Viral; Drug Therapy, Combination; Ethambutol; Female; Fluconazole; Humans; Isoniazid; Molluscum Contagiosum; Molluscum contagiosum virus; Multicenter Studies as Topic; Mycobacterium avium-intracellulare Infection; Ofloxacin; Patient Compliance; Pyrazinamide; Rifampin; Sequence Analysis, DNA; Tuberculosis	1996
Severe reduction in tacrolimus levels with rifampin despite multiple cytochrome P450 inhibitors: a case report. Transplantation proceedings, 2003, Volume: 35, Issue:7 Topics: Adult; Clarithromycin; Creatinine; Cytochrome P-450 Enzyme Inhibitors; Diltiazem; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Rifampin; Tacrolimus	2003
[Etiological analysis of ocular non-viral microbial isolates in children and their antibiotics susceptibility in vitro]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2009, Volume: 45, Issue:2 Topics: Adolescent; Anti-Infective Agents; Bacteria; Child; Child, Preschool; Drug Resistance, Microbial; Eye Infections; Female; Fluconazole; Humans; Infant; Infant, Newborn; Levofloxacin; Male; Microbial Sensitivity Tests; Mitosporic Fungi; Ofloxacin; Retrospective Studies; Rifampin	2009
An unusual case of Acanthamoeba peritonitis in a malnourished patient on continuous ambulatory peritoneal dialysis (CAPD). Journal of infection in developing countries, 2008, Apr-01, Volume: 2, Issue:2 Topics: Acanthamoeba; Amebiasis; Drug Therapy, Combination; Fluconazole; Humans; Immunocompromised Host; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Rifampin	2008
Acute liver failure in a pediatric patient with disseminated tuberculosis. Digestive diseases and sciences, 2011, Volume: 56, Issue:10 Topics: Antifungal Agents; Antitubercular Agents; Child; Coccidioidomycosis; Drug Therapy, Combination; Ethambutol; Fluconazole; Humans; Isoniazid; Liver Failure, Acute; Male; Pyrazinamide; Recovery of Function; Rifampin; Tuberculosis, Multidrug-Resistant	2011
Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot. Clinical pharmacology and therapeutics, 2012, Volume: 91, Issue:3 Topics: Administration, Oral; Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C9; Dried Blood Spot Testing; Fluconazole; Flurbiprofen; Genotype; Humans; Hydrolysis; Male; Rifampin; Young Adult	2012
Semi-mechanistic physiologically-based pharmacokinetic modeling of clinical glibenclamide pharmacokinetics and drug-drug-interactions. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Aug-16, Volume: 49, Issue:5 Topics: Animals; Anti-Infective Agents; CHO Cells; Clarithromycin; Computer Simulation; Cricetulus; Cytochrome P-450 Enzyme System; Drug Interactions; Fluconazole; Glyburide; HEK293 Cells; Humans; Hypoglycemic Agents; Models, Biological; Rifampin	2013
[In vivo evaluation of the metabolic ratio of CYP2C9 and CYP1A2 drug markers after administration of afobazole in comparison to standard inducers and inhibitors of cytochromes]. Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:11 Topics: Animals; Anti-Anxiety Agents; Anti-Bacterial Agents; Anticonvulsants; Antifungal Agents; Benzimidazoles; Ciprofloxacin; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Enzyme Inhibitors; Fluconazole; Male; Morpholines; Phenytoin; Rats; Rifampin	2013
Effects of rifampin and ketoconazole on pharmacokinetics of morinidazole in healthy chinese subjects. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:10 Topics: Animals; Antifungal Agents; Candida glabrata; Candidiasis; Cell Line; Female; Fluconazole; Fungal Proteins; Humans; Immunoblotting; Ketoconazole; Lectins; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Nitroimidazoles; Open Reading Frames; Rifampin	2014
Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib. Clinical pharmacology and therapeutics, 2015, Volume: 97, Issue:2 Topics: Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Drug Interactions; Erythromycin; Fasting; Fluconazole; Humans; Ketoconazole; Models, Biological; Nitriles; Prospective Studies; Pyrazoles; Pyrimidines; Retrospective Studies; Rifampin	2015
Naegleria fowleri That Induces Primary Amoebic Meningoencephalitis: Rapid Diagnosis and Rare Case of Survival in a 12-Year-Old Caucasian Girl. Laboratory medicine, 2016, Volume: 47, Issue:2 Topics: Amebiasis; Amphotericin B; Antiprotozoal Agents; Azithromycin; Central Nervous System Protozoal Infections; Cerebrospinal Fluid; Cerebrospinal Fluid Shunts; Child; Early Diagnosis; Female; Fluconazole; Humans; Hypothermia, Induced; Meningoencephalitis; Naegleria fowleri; Phosphorylcholine; Rifampin	2016
Are fluconazole or sertraline dose adjustments necessary with concomitant rifampin? HIV medicine, 2018, Volume: 19, Issue:6 Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antibiotics, Antitubercular; Antifungal Agents; Dose-Response Relationship, Drug; Drug Interactions; Fluconazole; HIV Infections; Humans; Mycoses; Rifampin; Sertraline; Tuberculosis	2018
Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software. Biopharmaceutics & drug disposition, 2018, Volume: 39, Issue:1 Topics: Ciprofloxacin; Clarithromycin; Computer Simulation; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Fluconazole; Humans; Itraconazole; Ketoconazole; Models, Biological; Paroxetine; Quinidine; Rifampin; Software	2018
Surgical infection prophylaxis prior to left ventricular assist device implantation: A survey of clinical practice. Journal of cardiac surgery, 2020, Volume: 35, Issue:10 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Aztreonam; Cephalosporins; Cross-Sectional Studies; Drug Therapy, Combination; Fluconazole; Heart-Assist Devices; Humans; Levofloxacin; Prosthesis Implantation; Prosthesis-Related Infections; Rifampin; Surgical Wound Infection; Surveys and Questionnaires; Vancomycin	2020
Physiologically based pharmacokinetic modeling and simulation to predict drug-drug interactions of ivosidenib with CYP3A perpetrators in patients with acute myeloid leukemia. Cancer chemotherapy and pharmacology, 2020, Volume: 86, Issue:5 Topics: Administration, Oral; Antineoplastic Agents; Area Under Curve; Computer Simulation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Fluconazole; Glycine; Healthy Volunteers; Humans; Itraconazole; Ketoconazole; Leukemia, Myeloid, Acute; Male; Microsomes, Liver; Models, Biological; Pyridines; Rifampin	2020
High frequency of azole resistant Candida spp. colonization among presumptive multidrug resistant tuberculosis (MDR-TB) patients. PloS one, 2020, Volume: 15, Issue:11 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Antitubercular Agents; Candida; Candidiasis; Child; Drug Interactions; Drug Resistance, Multiple, Fungal; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Rifampin; Species Specificity; Tuberculosis, Multidrug-Resistant; Young Adult	2020
Physiologically Based Pharmacokinetic Modeling for Selumetinib to Evaluate Drug-Drug Interactions and Pediatric Dose Regimens. Journal of clinical pharmacology, 2021, Volume: 61, Issue:11 Topics: Adolescent; Age Factors; Area Under Curve; Benzimidazoles; Body Surface Area; Child; Child, Preschool; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Drug Dosage Calculations; Drug Interactions; Fluconazole; Humans; Itraconazole; Metabolic Clearance Rate; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Rifampin	2021
Assessment of the Effects of Inhibition or Induction of CYP2C19 and CYP2C9 Enzymes, or Inhibition of OAT3, on the Pharmacokinetics of Abrocitinib and Its Metabolites in Healthy Individuals. European journal of drug metabolism and pharmacokinetics, 2022, Volume: 47, Issue:3 Topics: Adult; Area Under Curve; Clinical Trials, Phase I as Topic; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Drug Interactions; Fluconazole; Fluvoxamine; Humans; Probenecid; Pyrimidines; Rifampin; Sulfonamides	2022
Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans. European journal of clinical pharmacology, 2022, Volume: 78, Issue:6 Topics: Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Drug Interactions; Fluconazole; Humans; Midazolam; Omeprazole; Rifampin; Sodium Bicarbonate; Yohimbine	2022
Impact of narrowing perioperative antibiotic prophylaxis for left ventricular assist device implantation. Transplant infectious disease : an official journal of the Transplantation Society, 2022, Volume: 24, Issue:5 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefazolin; Ciprofloxacin; Fluconazole; Heart Failure; Heart-Assist Devices; Humans; Retrospective Studies; Rifampin; Treatment Outcome; Vancomycin	2022
Verifying in vitro-determined enzyme contributions to cannabidiol clearance for exposure predictions in human through physiologically-based pharmacokinetic modeling. CPT: pharmacometrics & systems pharmacology, 2023, Volume: 12, Issue:3 Topics: Adult; Cannabidiol; Child; Child, Preschool; Drug Interactions; Fluconazole; Humans; Itraconazole; Rifampin	2023
Case Report: Diffuse Cutaneous Leishmaniasis Successfully Treated with a Combination of Oral Rifampicin and Fluconazole. The American journal of tropical medicine and hygiene, 2023, 08-02, Volume: 109, Issue:2 Topics: Female; Fluconazole; Humans; Leishmania; Leishmaniasis, Cutaneous; Leishmaniasis, Diffuse Cutaneous; Middle Aged; Rifampin	2023