Compounds > fluconazole

fluconazole and phenobarbital

fluconazole has been researched along with phenobarbital in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (6.67)	18.2507
2000's	6 (40.00)	29.6817
2010's	8 (53.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Barber, N; Buckton, G; Oborne, CA	1
Hassim, SM; Samsudin, SH; Somchit, N	1
Ahmad Bustamam, A; Hasiah, AH; Israf, DA; Khairi, HM; Somchit, N; Sulaiman, MR; Wong, CW; Zuraini, A	1
Berthiaume, DR; Kline, KL	1
Inoue, K; Irie, K; Kodama, Y; Matsuo, S; Nishikawa, A; Ozawa, S; Takahashi, M; Tamura, K; Yoshida, M	1

Reviews

1 review(s) available for fluconazole and phenobarbital

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

14 other study(ies) available for fluconazole and phenobarbital

Article	Year
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
The interaction of albumin and drugs with two haemofiltration membranes. Journal of clinical pharmacy and therapeutics, 1994, Volume: 19, Issue:2 Topics: Barbital; Drug Interactions; Fluconazole; Membranes, Artificial; Phenobarbital; Polymers; Protein Binding; Renal Dialysis; Serum Albumin, Bovine	1994
Itraconazole- and fluconazole-induced toxicity in rat hepatocytes: a comparative in vitro study. Human & experimental toxicology, 2002, Volume: 21, Issue:1 Topics: Animals; Antifungal Agents; Cell Survival; Cells, Cultured; Cytochrome P-450 Enzyme System; Cytoprotection; Dose-Response Relationship, Drug; Enzyme Induction; Female; Fluconazole; Hepatocytes; Itraconazole; L-Lactate Dehydrogenase; Phenobarbital; Rats; Rats, Sprague-Dawley; Time Factors	2002
Involvement of phenobarbital and SKF 525A in the hepatotoxicity of antifungal drugs itraconazole and fluconazole in rats. Drug and chemical toxicology, 2006, Volume: 29, Issue:3 Topics: Animals; Antifungal Agents; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fluconazole; Hypnotics and Sedatives; Isoenzymes; Itraconazole; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley	2006
What is your neurologic diagnosis? C gattii infection. Journal of the American Veterinary Medical Association, 2012, Dec-01, Volume: 241, Issue:11 Topics: Animals; Anticonvulsants; Antifungal Agents; Cat Diseases; Cats; Central Nervous System Infections; Cryptococcosis; Cryptococcus gattii; Female; Fluconazole; Phenobarbital	2012
Dose-response involvement of constitutive androstane receptor in mouse liver hypertrophy induced by triazole fungicides. Toxicology letters, 2013, Jul-31, Volume: 221, Issue:1 Topics: Animals; Constitutive Androstane Receptor; Dose-Response Relationship, Drug; Enzyme Induction; Fluconazole; Fungicides, Industrial; Hepatomegaly; Liver; Male; Mice; Mice, Inbred C3H; Mice, Knockout; Phenobarbital; Receptors, Cytoplasmic and Nuclear; Triazoles	2013