fluconazole and metronidazole

fluconazole has been researched along with metronidazole in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (5.71)	18.2507
2000's	21 (30.00)	29.6817
2010's	40 (57.14)	24.3611
2020's	5 (7.14)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL	1
Gupta, G; Jain, A; Jain, RK; Kiran Kumar, ST; Kumar, L; Kumar, M; Maikhuri, JP; Sharma, VL; Shukla, PK	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Gupta, G; Jain, A; Kumar, A; Kumar, L; Kumar, R; Lal, N; Maikhuri, JP; Sarswat, A; Sharma, VL; Shukla, PK; Verma, V	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Gupta, G; Jain, A; Kiran Kumar, ST; Kumar, L; Kumar, S; Lal, N; Maikhuri, JP; Pandey, AK; Sarswat, A; Sharma, VL; Shukla, PK	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barad, HA; Gupta, VK; Kant, R; Pansuriya, BR; Parmar, NJ; Teraiya, SB	1
Barad, HA; Gupta, VK; Kant, R; Pansuriya, BR; Parmar, NJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bala, V; Gupta, G; Jangir, S; Kumar, L; Kumar, V; Kushwaha, B; Lal, N; Maikhuri, JP; Pandey, AK; Sarswat, A; Sharma, VL; Shukla, PK; Siddiqi, MI	1
Bala, V; Bhatta, RS; Chandasana, H; Chhonker, YS; Gupta, G; Gupta, S; Jangir, S; Krishna, A; Krishna, S; Kushwaha, B; Maikhuri, JP; Mandalapu, D; Rawat, K; Sankhwar, SN; Sharma, VL; Shukla, PK; Siddiqi, MI; Singh, M; Tripathi, R	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bala, V; Gupta, G; Jain, A; Jangir, S; Krishna, S; Kumar, L; Kushwaha, B; Lal, N; Maikhuri, JP; Mandalapu, D; Pandey, AK; Rawat, T; Sarswat, A; Sharma, VL; Shukla, PK; Siddiqi, MI	1
Chandrasekaran, B; Cherukupalli, S; Hampannavar, GA; Karpoormath, R; Palakollu, VN; Thapliyal, N	1
Gao, WW; Gopala, L; Li, ZZ; Tangadanchu, VKR; Zhou, CH	1
Chauhan, BS; Goyani, R; Gupta, G; Gupta, S; Krishna, S; Kumar, B; Kushwaha, B; Lal, J; Maikhuri, JP; Mandalapu, D; Sashidhara, KV; Sharma, VL; Shukla, M; Shukla, PK; Siddiqi, MI; Singh, P; Srivastava, N; Tripathi, R	1
Ba, Y; Hou, X; Wang, S; Xu, Z; Yang, H; Zhang, J	1
Beteck, RM; Jesumoroti, OJ; Legoabe, LJ; Patel, OPS	1
Daujat, M; Domergue, J; Fabre, I; Joyeux, H; Maurel, P; Maurice, M; Pichard, L	1
Durham, T; Johansson, SL; Kaufman, L; Swindells, S	1
Croucher, PE; Dockerty, WG; Sonnex, C	1
Bańcer, M; Bejm, J; Peterek, J; Stawarz, B; Sulik, M; Zabkowski, T	1
Beelen, DW; Dermoumi, H; Elmaagacli, A; Heintschel von Heinegg, E; Müller, KD; Peceny, R; Runde, V; Schaefer, UW; Trenschel, R	1
Ressel, GW	1
Avorn, J; Fischer, MA; Solomon, DH; Teich, JM	1
Arora, R; Batra, S; Malhotra, M; Sharma, JB; Sharma, S	1
Chanana, C; Mittal, S; Raina, U; Sharma, JB	1
Karabetsos, D; Koutentakis, D; Ntouros, D; Vakis, A	1
Ortiz-Ibarra, J; Reyna-Figueroa, J; Villagrana-Zesati, R	1
Ditmer, D; Feldstein, AC; Krall, M; Perrin, N; Platt, R; Simon, SR; Sittig, DF; Smith, DH; Soumerai, SB; Yang, X	1
Blikslager, AT; Davis, JL; Little, D; Papich, MG	1
Agyarko-Poku, T; Asamoah-Adu, C; Deslandes, S; Diakité, S; Frost, E; Khonde, N; Labbé, AC; Pépin, J; Sobela, F; Sylla, M	1
Baeten, JM; Chohan, V; Hassan, WM; Holmes, KK; Jaoko, W; Kiarie, J; Kurth, AE; Lavreys, L; Mandaliya, K; McClelland, RS; Ndinya-Achola, JO; Richardson, BA	1
Kekulé, AS; Kreft, B; Lübbert, C; Marsch, WC; Oehme, A	1
Barshikar, S; Baylor, AE; Dolman, HS; Glowniak, J; Hong, K; Lavery, T; Nailor, M; Singla, R; Stassinopoulus, J; Tyburski, JG; Wilson, RF; Zimmerman, LH	1
Khan, AS; Khan, S; Sheikh, Z	1
Balkus, JE; Farquhar, C; Gitau, R; Jaoko, W; Kiarie, J; Mandaliya, K; Marrazzo, J; Masese, L; McClelland, RS; Richardson, BA	1
Li, B; Yu, K; Zhang, T	1
Andreeva, IV; Belikov, AN; Evstaf'ev, VV; Fokin, AA; Grinev, AV; Khrianin, AA; Kirpicheva, NN; Korolev, SV; Kozlov, SN; Serdiutskaia, MV; Stetsiuk, OU	1
Al Omran, Y; Anwuzia-Iwegbu, C; Heaford, A	1
Balkus, JE; McClelland, RS; Mochache, V	1
Dettloff, J; Kassim, A; Reddy, SB; Reddy, VB; Waldman, L	1
Buffon, R; Manzoor, S; Rossi, AV	1
Hersh, EV; Moore, PA	1
Brandsborg, E; Hammarström, L; Larsson, PG; Marcotte, H; Pendharkar, S	1
Ali, I; Babik, JM; Brondfield, MN; Cope, JR; DeMarco, T; Doernberg, SB; Hilts-Horeczko, A; Klein, L; Matanock, A; Reid, MJ; Ritter, JM; Rutishauser, RL; Tang, J	1
Pararajasingam, A; Uwagwu, J	1
Domenici, L; Giorgini, M; Palma, E; Panici, PB; Pierangeli, A; Recine, N	1
Geballa-Koukoula, A; Geballa-Koukoulas, K; Gennimata, D; Kavvalou, E; Panderi, I; Panteri-Petratou, E; Vourna, P; Zervas, K	1
Aldrovandi, GM; Cunningham, NJ; Kordy, K; Lee, DJ; Li, F; Romeo, AC; Saavedra, M; Tobin, N; Zabih, S	1
Nayak, C; Tambe, S; Zambare, U	1
Battini, N; Hu, YY; Yadav Bheemanaboina, RR; Zhou, CH	1
Bastianpillai, J; Chaudhry, S; Vijendren, A	1
Cianci, A; Corsello, S; Ettore, G; Genovese, C; Mattana, P; Tempera, G	1
Goh, LH; Logan, S; Sim, M	1
Achachi, N; Matmour, D; Toumi, H	1
Akbar, N; Hussain, K; Khalid, M; Khan, NA; Shah, MR; Siddiqui, R	1
Arriaga-García, FJ; Medellín-Garibay, SE; Milán-Segovia, RDC; Pérez-González, LF; Rodríguez-Báez, AS; Romano-Moreno, S; Velarde-Salcedo, R	1

Reviews

8 review(s) available for fluconazole and metronidazole

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold. European journal of medicinal chemistry, 2017, Jan-27, Volume: 126 Topics: Animals; Chemistry Techniques, Synthetic; Humans; Pyrazoles; Pyrimidines	2017
Nitroimidazole-containing compounds and their antibacterial and antitubercular activities. European journal of medicinal chemistry, 2019, Oct-01, Volume: 179 Topics: Anti-Bacterial Agents; Bacterial Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles	2019
Metronidazole-conjugates: A comprehensive review of recent developments towards synthesis and medicinal perspective. European journal of medicinal chemistry, 2021, Jan-15, Volume: 210 Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antiprotozoal Agents; Drug Development; Humans; Hypoglycemic Agents; Metronidazole	2021
Oral histoplasmosis in a patient infected with HIV. A case report. Oral surgery, oral medicine, and oral pathology, 1994, Volume: 77, Issue:2 Topics: Adult; AIDS-Related Opportunistic Infections; Fluconazole; Histoplasmosis; Humans; Male; Metronidazole; Mouth Diseases	1994
Three Serious Drug Interactions that Every Dentist Should Know About. Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995), 2015, Volume: 36, Issue:6 Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Bradycardia; Cytochrome P-450 CYP2C9; Dental Care; Drug Interactions; Epinephrine; Fluconazole; Hemorrhage; Humans; International Normalized Ratio; Lithium; Metronidazole; Propranolol; Warfarin	2015
Disseminated Acanthamoeba infection in a heart transplant recipient treated successfully with a miltefosine-containing regimen: Case report and review of the literature. Transplant infectious disease : an official journal of the Transplantation Society, 2017, Volume: 19, Issue:2 Topics: Acanthamoeba; Amebiasis; Amebicides; Amphotericin B; Anti-Bacterial Agents; Antilymphocyte Serum; Biopsy; Cardiomyopathies; Drugs, Investigational; Endoscopy; Female; Fluconazole; Flucytosine; Heart Transplantation; Humans; Immunocompromised Host; Immunosuppressive Agents; Magnetic Resonance Imaging; Metacarpal Bones; Metronidazole; Middle Aged; Phosphorylcholine; Polymerase Chain Reaction; Radiography; Sinusitis; Skin	2017
Combined systemic (fluconazole) and topical (metronidazole + clotrimazole) therapy for a new approach to the treatment and prophylaxis of recurrent candidiasis. Minerva ginecologica, 2019, Volume: 71, Issue:4 Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Candidiasis, Vulvovaginal; Clotrimazole; Drug Therapy, Combination; Female; Fluconazole; Humans; Metronidazole; Probiotics; Recurrence	2019

Trials

10 trial(s) available for fluconazole and metronidazole

Article	Year
Fungal colonization and invasive fungal infections following allogeneic BMT using metronidazole, ciprofloxacin and fluconazole or ciprofloxacin and fluconazole as intestinal decontamination. Bone marrow transplantation, 2000, Volume: 26, Issue:9 Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antifungal Agents; Aspergillosis; Bacteria, Anaerobic; Bone Marrow Transplantation; Candidiasis; Cause of Death; Ciprofloxacin; Disease Susceptibility; Female; Fluconazole; Fungemia; Fungi; Hematologic Neoplasms; Humans; Immunocompromised Host; Immunosuppressive Agents; Incidence; Intestinal Diseases; Intestines; Male; Metronidazole; Middle Aged; Mycoses; Neuroaspergillosis; Opportunistic Infections; Premedication; Prospective Studies; Superinfection; Transplantation Conditioning; Treatment Outcome	2000
Ciprofloxacin-tinidazole combination, fluconazole- azithromicin-secnidazole-kit and doxycycline- metronidazole combination therapy in syndromic management of pelvic inflammatory disease: a prospective randomized controlled trial. Indian journal of medical sciences, 2003, Volume: 57, Issue:12 Topics: Adolescent; Adult; Azithromycin; Ciprofloxacin; Doxycycline; Drug Therapy, Combination; Female; Fluconazole; Humans; Metronidazole; Pelvic Inflammatory Disease; Prospective Studies; Tinidazole	2003
Comparative efficacy of two regimens in syndromic management of lower genital infections. Archives of gynecology and obstetrics, 2006, Volume: 273, Issue:4 Topics: Administration, Intravaginal; Adult; Anti-Infective Agents, Local; Azithromycin; Clotrimazole; Drug Therapy, Combination; Female; Fluconazole; Humans; Metronidazole; Pruritus; Vaginitis	2006
Short-term therapy for mixed vaginal infections. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2006, Volume: 92, Issue:2 Topics: Administration, Oral; Antifungal Agents; Antiprotozoal Agents; Antitrichomonal Agents; Candidiasis, Vulvovaginal; Drug Therapy, Combination; Female; Fluconazole; Humans; Itraconazole; Metronidazole; Patient Compliance; Tinidazole; Treatment Outcome; Trichomonas Vaginitis; Vaginosis, Bacterial	2006
Reducing warfarin medication interactions: an interrupted time series evaluation. Archives of internal medicine, 2006, May-08, Volume: 166, Issue:9 Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Drug Interactions; Drug Prescriptions; Education, Medical, Continuing; Female; Fluconazole; Health Maintenance Organizations; Humans; Male; Medical Records Systems, Computerized; Metronidazole; Middle Aged; Sulfamethoxazole; Warfarin	2006
The syndromic management of vaginal discharge using single-dose treatments: a randomized controlled trial in West Africa. Bulletin of the World Health Organization, 2006, Volume: 84, Issue:9 Topics: Adolescent; Adult; Africa, Western; Animals; Anti-Infective Agents; Antifungal Agents; Antitrichomonal Agents; Candida; Child; Clotrimazole; Drug Therapy, Combination; Female; Fluconazole; Humans; Metronidazole; Mycoplasma genitalium; Neisseria gonorrhoeae; Sex Work; Syndrome; Tinidazole; Treatment Outcome; Trichomonas vaginalis; Vaginal Discharge	2006
Improvement of vaginal health for Kenyan women at risk for acquisition of human immunodeficiency virus type 1: results of a randomized trial. The Journal of infectious diseases, 2008, May-15, Volume: 197, Issue:10 Topics: Adolescent; Adult; Anti-Infective Agents; Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; HIV Infections; HIV-1; Humans; Incidence; Kenya; Lactobacillus; Metronidazole; Middle Aged; Placebos; Sex Work; Trichomonas Vaginitis; Vagina; Vaginosis, Bacterial	2008
The posttrial effect of oral periodic presumptive treatment for vaginal infections on the incidence of bacterial vaginosis and Lactobacillus colonization. Sexually transmitted diseases, 2012, Volume: 39, Issue:5 Topics: Adolescent; Adult; Anti-Infective Agents; Antifungal Agents; Cohort Studies; Female; Fluconazole; Follow-Up Studies; Humans; Incidence; Kenya; Lactobacillus; Metronidazole; Proportional Hazards Models; Prospective Studies; Risk Factors; Sex Work; Treatment Outcome; Vagina; Vaginosis, Bacterial; Young Adult	2012
Vaginal colonisation by probiotic lactobacilli and clinical outcome in women conventionally treated for bacterial vaginosis and yeast infection. BMC infectious diseases, 2015, Jul-03, Volume: 15 Topics: Administration, Intravaginal; Adult; Anti-Bacterial Agents; Antifungal Agents; Candidiasis, Vulvovaginal; Carrier State; Clindamycin; Drug Therapy, Combination; Female; Fluconazole; Humans; Lactobacillus; Metronidazole; Middle Aged; Probiotics; Treatment Outcome; Vagina; Vaginosis, Bacterial; Young Adult	2015
Long-term Lactobacillus rhamnosus BMX 54 application to restore a balanced vaginal ecosystem: a promising solution against HPV-infection. BMC infectious diseases, 2018, 01-05, Volume: 18, Issue:1 Topics: Administration, Intravaginal; Adult; Female; Fluconazole; Humans; Lacticaseibacillus rhamnosus; Metronidazole; Microbiota; Papillomavirus Infections; Probiotics; Treatment Outcome; Vagina; Vaginosis, Bacterial	2018

Other Studies

52 other study(ies) available for fluconazole and metronidazole

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogPoct: a tool for lipophilicity determination in drug discovery. Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:3 Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase	2007
Carbodithioic acid esters of fluoxetine, a novel class of dual-function spermicides. European journal of medicinal chemistry, 2008, Volume: 43, Issue:10 Topics: Animals; Esters; Fluoxetine; Fungi; Spermatocidal Agents; Trichomonas vaginalis	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Imidazole derivatives as possible microbicides with dual protection. European journal of medicinal chemistry, 2010, Volume: 45, Issue:2 Topics: Animals; Anti-Infective Agents; Cell Survival; Fungi; HeLa Cells; Humans; Imidazoles; Male; Microbial Sensitivity Tests; Spermatozoa; Trichomonas vaginalis	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Design and synthesis of 3-(azol-1-yl)phenylpropanes as microbicidal spermicides for prophylactic contraception. Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1 Topics: Anti-Infective Agents; Antifungal Agents; Contraceptive Agents, Female; Drug Design; Female; HeLa Cells; Humans; Lactobacillus; Propane; Spermatocidal Agents; Structure-Activity Relationship; Trichomonas vaginalis	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
An efficient one-pot synthesis, structure, antimicrobial and antioxidant investigations of some novel quinolyldibenzo[b,e][1,4]diazepinones. Bioorganic & medicinal chemistry letters, 2012, Jun-01, Volume: 22, Issue:11 Topics: Anti-Infective Agents; Antioxidants; Azepines; Crystallography, X-Ray; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Conformation; Quinolines	2012
An improved microwave assisted one-pot synthesis, and biological investigations of some novel aryldiazenyl chromeno fused pyrrolidines. Bioorganic & medicinal chemistry letters, 2012, Jun-15, Volume: 22, Issue:12 Topics: Antifungal Agents; Antitubercular Agents; Aspergillus fumigatus; Azo Compounds; Benzopyrans; Candida albicans; Crystallography, X-Ray; Gram-Negative Bacteria; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Microwaves; Molecular Structure; Mycobacterium tuberculosis; Pyrrolidines; Stereoisomerism; Thiosemicarbazones	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Azole-carbodithioate hybrids as vaginal anti-Candida contraceptive agents: design, synthesis and docking studies. European journal of medicinal chemistry, 2013, Volume: 70 Topics: Anti-Bacterial Agents; Antifungal Agents; Antiprotozoal Agents; Azoles; Candida; Drug Design; Escherichia coli; HeLa Cells; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Sulfhydryl Compounds; Trichomonas vaginalis	2013
N-Alkyl/aryl-4-(3-substituted-3-phenylpropyl)piperazine-1-carbothioamide as dual-action vaginal microbicides with reverse transcriptase inhibition. European journal of medicinal chemistry, 2015, Aug-28, Volume: 101 Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Dose-Response Relationship, Drug; Female; HeLa Cells; Humans; Lactobacillus acidophilus; Male; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Parasitic Sensitivity Tests; Piperazines; Rabbits; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spermatocidal Agents; Spermatozoa; Structure-Activity Relationship; Thioamides; Trichomonas vaginalis; Vagina	2015
Role of disulfide linkage in action of bis(dialkylaminethiocarbonyl)disulfides as potent double-Edged microbicidal spermicide: Design, synthesis and biology. European journal of medicinal chemistry, 2016, Jun-10, Volume: 115 Topics: Animals; Anti-Infective Agents; Candida; Disulfides; Male; Mice; Rabbits; Spermatocidal Agents; Spermatozoa; Trichomonas vaginalis	2016
Discovery of novel nitroimidazole enols as Pseudomonas aeruginosa DNA cleavage agents. Bioorganic & medicinal chemistry, 2017, 12-15, Volume: 25, Issue:24 Topics: Albumins; Anti-Bacterial Agents; DNA Cleavage; DNA Replication; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Discovery; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles; Pseudomonas aeruginosa; Quantum Theory; Structure-Activity Relationship	2017
Substituted carbamothioic amine-1-carbothioic thioanhydrides as novel trichomonicidal fungicides: Design, synthesis, and biology. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Carbonic Anhydrases; Dose-Response Relationship, Drug; Drug Design; Fungicides, Industrial; Metronidazole; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Sulfhydryl Compounds; Trichomonas	2018
Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1992, Jan-06, Volume: 6, Issue:2 Topics: Blotting, Northern; Cells, Cultured; Clotrimazole; Cytochrome P-450 Enzyme System; Fluconazole; Humans; Imidazoles; Kinetics; Liver; Metronidazole; Miconazole; Microsomes, Liver; Mixed Function Oxygenases; RNA; RNA, Messenger	1992
Balanoposthitis associated with the presence of subpreputial "smegma stones". Genitourinary medicine, 1997, Volume: 73, Issue:6 Topics: Adult; Antifungal Agents; Balanitis; Calculi; Fluconazole; Humans; Hygiene; Male; Metronidazole; Smegma	1997
[The results of treatment of chronic prostatitis on the background of anaerobic bacterial and fungal infections]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1999, Volume: 52, Issue:9-10 Topics: Adolescent; Adult; Anti-Infective Agents; Antifungal Agents; Bacterial Infections; Chronic Disease; Fluconazole; Humans; Male; Metronidazole; Prostatitis	1999
CDC releases 2002 guidelines for treating STDs: Part I. Diseases characterized by vaginal discharge and PID. American family physician, 2002, Nov-01, Volume: 66, Issue:9 Topics: Anti-Infective Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Metronidazole; Pelvic Inflammatory Disease; Sexually Transmitted Diseases; Trichomonas Vaginitis; Vaginal Discharge; Vaginosis, Bacterial	2002
Conversion from intravenous to oral medications: assessment of a computerized intervention for hospitalized patients. Archives of internal medicine, 2003, Nov-24, Volume: 163, Issue:21 Topics: Administration, Oral; Amiodarone; Drug Therapy, Computer-Assisted; Fluconazole; Humans; Infusions, Intravenous; Levofloxacin; Medication Systems, Hospital; Metronidazole; Ofloxacin; Practice Patterns, Physicians'; Ranitidine; Reminder Systems	2003
Intracerebral CSF collection mimicking cerebral abscess in a patient suffering from cryptococcal meningitis. The Journal of infection, 2005, Volume: 51, Issue:4 Topics: Acyclovir; Aged; Amphotericin B; Anti-Infective Agents; Brain Abscess; Ceftriaxone; Cerebrospinal Fluid; Cerebrospinal Fluid Pressure; Diagnosis, Differential; Drainage; Fluconazole; Humans; Magnetic Resonance Imaging; Male; Meningitis, Cryptococcal; Metronidazole; Spinal Puncture; Teicoplanin	2005
Mucosal permeability of water-soluble drugs in the equine jejunum: a preliminary investigation. Journal of veterinary pharmacology and therapeutics, 2006, Volume: 29, Issue:5 Topics: Animals; Anti-Infective Agents; Biological Availability; Cephalexin; Fluconazole; Fluoroquinolones; Horses; Intestinal Mucosa; Jejunum; Linear Models; Metronidazole; Permeability; Quinolones; Solubility	2006
[37-year old patient with fever, diarrhea and lymphadenopathy]. Der Internist, 2010, Volume: 51, Issue:8 Topics: Adult; AIDS Serodiagnosis; AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Antifungal Agents; Antiretroviral Therapy, Highly Active; Candidiasis, Oral; Ciprofloxacin; Clarithromycin; Diagnosis, Differential; Diarrhea; Drug Therapy, Combination; Fever of Unknown Origin; Fluconazole; Giardia lamblia; Giardiasis; HIV Seropositivity; HIV-1; Homosexuality, Male; Humans; Immunoblotting; Lymphatic Diseases; Male; Metronidazole; Omeprazole	2010
Impact of evaluating antibiotic concentrations in abdominal abscesses percutaneously drained. American journal of surgery, 2011, Volume: 201, Issue:3 Topics: Abdominal Abscess; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; Exudates and Transudates; Female; Fluconazole; Humans; Male; Metronidazole; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Suction; Treatment Outcome; Vancomycin	2011
Lingua villosa nigra. Lancet (London, England), 2011, Apr-02, Volume: 377, Issue:9772 Topics: Anti-Infective Agents; Antifungal Agents; Candidiasis; Clavulanic Acid; Female; Fluconazole; Humans; Metronidazole; Middle Aged; Pelvic Infection; Postoperative Complications; Tongue, Hairy; Treatment Outcome	2011
Direct rapid analysis of multiple PPCPs in municipal wastewater using ultrahigh performance liquid chromatography-tandem mass spectrometry without SPE pre-concentration. Analytica chimica acta, 2012, Aug-13, Volume: 738 Topics: Acyclovir; Benzophenones; Carbamazepine; Chromatography, High Pressure Liquid; Fluconazole; Fluoxetine; Hong Kong; Metronidazole; Parabens; Pharmaceutical Preparations; Ranitidine; Sewage; Solid Phase Extraction; Sunscreening Agents; Tandem Mass Spectrometry	2012
[Diagnostic and treatment patterns in management of male patients with nongonococcal urethritis: results of Russian multicentral cross-sectional study]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2012, Volume: 57, Issue:5-6 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antiprotozoal Agents; Azithromycin; Ceftriaxone; Chlamydia trachomatis; Cross-Sectional Studies; Doxycycline; Fluconazole; Guideline Adherence; Humans; Josamycin; Male; Metronidazole; Middle Aged; Mycoplasma genitalium; Mycoplasma hominis; Ofloxacin; Polymerase Chain Reaction; Practice Guidelines as Topic; Retrospective Studies; Russia; Trichomonas vaginalis; Ureaplasma urealyticum; Urethra; Urethritis	2012
Against all odds. Conservative management of Boerhaave's syndrome. BMJ case reports, 2014, May-21, Volume: 2014 Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Bacterial Agents; Antifungal Agents; Drainage; Esophageal Perforation; Fluconazole; Humans; Male; Mediastinal Diseases; Metronidazole; Pantoprazole; Parenteral Nutrition; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pleural Effusion; Proton Pump Inhibitors	2014
Periodic presumptive treatment for women with prevalent vaginal infections: secondary analysis of data from a randomized controlled trial. Sexually transmitted diseases, 2014, Volume: 41, Issue:7 Topics: Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Chemoprevention; Female; Fluconazole; Humans; Kenya; Metronidazole; Prevalence; Randomized Controlled Trials as Topic; Sex Workers; Treatment Outcome; Trichomonas Vaginitis; Vaginosis, Bacterial	2014
Neutrophilic Fixed Drug Eruption. The American Journal of dermatopathology, 2015, Volume: 37, Issue:7 Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Drug Eruptions; Female; Fluconazole; Humans; Metronidazole; Naproxen; Neutrophils; Pregnancy; Pregnancy Complications	2015
Molecularly imprinted solid phase extraction of fluconazole from pharmaceutical formulations. Talanta, 2015, Volume: 134 Topics: Acetonitriles; Fluconazole; Imidazoles; Methacrylates; Metronidazole; Miconazole; Molecular Imprinting; Polymers; Solid Phase Extraction	2015
BMJ case reports, 2017, Sep-13, Volume: 2017 Topics: Aged; Anti-Bacterial Agents; Colony Count, Microbial; Drainage; Female; Fluconazole; Humans; Immunocompromised Host; Lactobacillus; Lethargy; Linezolid; Liver Abscess; Metronidazole; Microbial Sensitivity Tests; Pleural Effusion; Probiotics; Sepsis; Treatment Outcome; Venous Thrombosis	2017
A porous graphitized carbon LC-ESI/MS method for the quantitation of metronidazole and fluconazole in breast milk and human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, May-01, Volume: 1084 Topics: Acetonitriles; Chromatography, Liquid; Female; Fluconazole; Graphite; Humans; Limit of Detection; Linear Models; Male; Metronidazole; Milk, Human; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization	2018
Combination Antibiotics Improves Disease Activity and Alters Microbial Communities in Children With Ulcerative Colitis. Journal of pediatric gastroenterology and nutrition, 2018, Volume: 67, Issue:3 Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Child; Colitis, Ulcerative; Doxycycline; Female; Fluconazole; Gastrointestinal Microbiome; Humans; Male; Metronidazole; Retrospective Studies; Vancomycin; Young Adult	2018
Nodulo-ulcerative and erythrodermic secondary syphilis in human immunodeficiency virus-infected individuals. International journal of STD & AIDS, 2019, Volume: 30, Issue:5 Topics: Administration, Oral; Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Chancre; Coinfection; Fluconazole; HIV Seropositivity; Humans; Injections, Intravenous; Male; Metronidazole; Penicillins; Skin Ulcer; Syphilis; Treatment Outcome	2019
Sulfonamide-Derived Four-Component Molecular Hybrids as Novel DNA-Targeting Membrane Active Potentiators against Clinical Escherichia coli. Molecular pharmaceutics, 2019, 03-04, Volume: 16, Issue:3 Topics: Anti-Bacterial Agents; Antifungal Agents; Azoles; Carbonic Anhydrases; Cell Membrane Permeability; Cell Survival; DNA, Bacterial; Drug Compounding; Drug Resistance, Bacterial; Drug Resistance, Fungal; Drug Therapy, Combination; Escherichia coli; Ethanol; Fluconazole; Humans; Hydrogen Bonding; Isoenzymes; MCF-7 Cells; Metronidazole; Models, Molecular; Molecular Docking Simulation; Norfloxacin; Piperazine; Sulfonamides	2019
Rare case of a 3-year-old with BMJ case reports, 2019, Apr-08, Volume: 12, Issue:4 Topics: Administration, Intravenous; Anti-Bacterial Agents; Antifungal Agents; Candida albicans; Candidiasis; Ceftriaxone; Child, Preschool; Facial Paralysis; Female; Fluconazole; Humans; Magnetic Resonance Imaging; Mastoid; Mastoidectomy; Metronidazole; Osteomyelitis; Skull Base; Tomography, X-Ray Computed	2019
Vaginal discharge: evaluation and management in primary care. Singapore medical journal, 2020, Volume: 61, Issue:6 Topics: Anti-Infective Agents; Antifungal Agents; Female; Fluconazole; Humans; Metronidazole; Primary Health Care; Sexually Transmitted Diseases; Singapore; Vaginal Discharge	2020
Quality of Active Pharmaceutical Ingredients Present on Algerian Soil: Control of Impurities of Ciprofloxacin, Metronidazole and Fluconazole. Annales pharmaceutiques francaises, 2022, Volume: 80, Issue:3 Topics: Algeria; Ciprofloxacin; Drug Contamination; Fluconazole; Metronidazole; Pharmaceutical Preparations; Soil	2022
Azole and 5-nitroimidazole based nanoformulations are potential antiamoebic drug candidates against brain-eating amoebae. Journal of applied microbiology, 2023, Apr-03, Volume: 134, Issue:4 Topics: Amebicides; Amoeba; Antiprotozoal Agents; Azoles; Brain; Fluconazole; Humans; Itraconazole; Metronidazole; Naegleria fowleri	2023
Model-informed precision dosing of antimicrobial drugs in pediatrics: experiences from a pilot scale program. European journal of pediatrics, 2023, Volume: 182, Issue:9 Topics: Anti-Bacterial Agents; Bayes Theorem; Child; Clindamycin; Critical Illness; Fluconazole; Humans; Linezolid; Meropenem; Metronidazole; Neoplasms; Piperacillin; Vancomycin	2023