fluconazole has been researched along with ketoconazole in 570 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 52 (9.12) | 18.7374 |
1990's | 217 (38.07) | 18.2507 |
2000's | 159 (27.89) | 29.6817 |
2010's | 120 (21.05) | 24.3611 |
2020's | 22 (3.86) | 2.80 |
Authors | Studies |
---|---|
Algueró, M; Bartroli, J; Boncompte, E; Forn, J; García-Rafanell, J; Turmo, E; Vericat, ML | 1 |
Kukla, MJ; Liu, L; Marichal, P; Odds, F; Saha, AK; Simoneaux, RL | 1 |
Buchta, V; Fáková, H; Koudelka, P; Kubanová, P; Pour, M; Pourová, H; Schiller, R; Spulák, M; Voprsalová, M; Wsól, V | 1 |
Casciano, CN; Clement, RP; Johnson, WW; Lew, K; Wang, EJ | 1 |
Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K | 1 |
Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K | 1 |
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK | 1 |
Artico, M; D'Auria, FD; De Martino, G; Di Pasquali, A; La Regina, G; Nencioni, L; Palamara, AT; Silvestri, R | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Ji, H; Jiang, Q; Lü, J; Miao, Z; Sheng, C; Song, Y; Xu, H; Yao, J; Zhang, M; Zhang, W; Zhou, Y; Zhu, J | 1 |
Bergès, T; Bouchara, JP; Chabasse, D; Hennequin, C; Tronchin, G; Vandeputte, P | 1 |
Ekins, S; Harwood, HJ; Hoover, DJ; Lawton, MP; Mankowski, DC; Treadway, JL | 1 |
Cheng, S; Clancy, CJ; Clapp, W; Nguyen, KT; Nguyen, MH | 1 |
Cao, YB; Jiang, YY; Sun, QY; Wu, QY; Xu, JM; Zhang, DZ; Zhang, J; Zhang, WN; Zhao, HQ | 1 |
Kang, TH; Kim, S; Park, JS; Suh, YG; Yu, KA | 1 |
Alvarado-Ramírez, E; Torres-Rodríguez, JM | 1 |
Almyroudis, NG; Fothergill, AW; Kusne, S; Rinaldi, MG; Sutton, DA | 1 |
Chaffin, WL; Mekala, S; Perumal, P | 1 |
Herrmann, JV; Miltenberger, R; Müller, FM; Salvenmoser, S; Staudigel, A; Tredup, A | 1 |
Calderone, R; Chauhan, N; Kruppa, M | 1 |
Cao, Y; Chen, J; Ji, H; Jiang, Y; Li, Y; Liang, R; Lü, J; Tang, H; Yao, B; Zheng, C; Zhou, Y; Zhu, J | 1 |
Acimovic, J; Kocjan, D; Korosec, T; Rozman, D; Seliskar, M; Tacer, KF; Urleb, U | 1 |
Enriz, RD; Freile, M; Gupta, MP; Kouznetsov, VV; Sortino, M; Vargas Méndez, LY; Vásquez, Y; Zacchino, SA | 1 |
Cano, J; Gené, J; Guarro, J; Marimon, R; Serena, C | 1 |
Buitrago, MJ; Cuenca-Estrella, M; Gomez-Lopez, A; Gutierrez, MO; Rodriguez-Tudela, JL | 1 |
Agarwal, AK; Ashfaq, MK; Babu, KS; Clark, AM; Elsohly, HN; Jacob, MR; Khan, SI; Li, XC; Manly, SP | 1 |
Jiang, Y; Jin, Y; Li, P; Liu, P; Sun, P; Sun, Q; Wu, Q; Xie, W; Yang, X; Zhang, D; Zhang, Y; Zhu, S | 1 |
Artico, M; Botta, M; Caporuscio, F; Cirilli, R; D'Auria, FD; De Melo, NR; Kelly, SL; La Regina, G; La Torre, F; Lamb, DC; Nencioni, L; Olla, S; Palamara, AT; Piscitelli, F; Silvestri, R; Tafi, A | 1 |
Kelly, DE; Kelly, SL; Manning, NJ; Merkamm, M; Parker, JE; Pompon, D | 1 |
Bergès, T; Bouchara, JP; Chabasse, D; Ernoult, E; Larcher, G; Tronchin, G; Vandeputte, P | 1 |
Cannon, RD; Holmes, AR; Lamping, E; Nakamura, K; Niimi, K; Niimi, M; Ranchod, A; Tyndall, JD | 1 |
Jackson, CJ; Kelly, DE; Kelly, SL; Lamb, DC; Marczylo, TH; Parker, JE; Warrilow, AG | 1 |
Chai, X; Dan, Z; Hu, H; Jiang, Y; Sun, Q; Wu, Q; Yu, S; Zhang, J | 1 |
Aher, NG; Bhat, MK; Kumar, A; Mishra, NN; Pore, VS; Sharma, A; Shukla, PK | 1 |
Pratim Roy, P; Roy, K | 1 |
Cheng, A; Lou, H; Sun, L; Sun, S; Wu, X; Zhang, Y | 1 |
Alexopoulos, EC; Antonopoulou, S; Aoun, M; Baka, S; Grigoriou, O; Kalambokas, T; Kouskouni, E; Logothetis, E; Papadias, K; Velegraki, A; Zannos, A | 1 |
Rahkhoodaee, F; Raymond, M; Tsao, S | 1 |
Chai, X; Dan, Z; Hu, H; Wu, Q; Yu, S; Zhang, D; Zhang, J; Zhao, Q; Zou, Y | 1 |
Bergès, T; Bouchara, JP; Chabasse, D; Renier, G; Rocher, F; Tronchin, G; Vandeputte, P | 1 |
Cenci, E; Costantino, G; Fringuelli, R; Giacchè, N; Macchiarulo, A; Milanese, L; Schiaffella, F; Vecchiarelli, A | 1 |
Gao, C; Pang, G; Sun, S; Wang, B; Xu, Y; Zhao, D; Zhou, L | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Kumar, A; Mathew, BP; Nath, M; Sharma, S; Shukla, PK | 1 |
Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Warrilow, AG; Weig, M | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Aytemir, MD; Ozçelik, B | 1 |
Chai, X; Guan, Z; Hu, H; Sun, Q; Wu, Q; Yan, Y; Yu, S; Zou, Y | 1 |
Bader, O; Gross, U; Kelly, DE; Kelly, SL; Martel, CM; Parker, JE; Rolley, N; Warrilow, AG; Weig, M | 1 |
Ghosh, I; Manoharlal, R; Prakash, O; Prasad, R; Puri, N; Sharma, M | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
Cao, Y; Chai, X; Jiang, Y; Sun, Q; Wu, Q; Xu, J; Yu, S; Zhang, D; Zhang, J; Zou, Y | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Juvonen, RO; Koskiranta, J; Ollakka, R; Rahnasto-Rilla, M; Raunio, H; Ritvanen, A; Salminen, KA; Tani, N; Wittekindt, C | 1 |
Arun, Y; Balachandran, C; Bhaskar, G; Perumal, PT; Saikumar, C | 1 |
Chai, X; Hu, H; Liao, J; Wu, Q; Xu, M; Yu, S; Zhao, Q; Zou, Y | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Emami, S; Faramarzi, MA; Irannejad, H; Samadi, N; Shojapour, S | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chai, X; Ding, H; Li, L; Wang, B; Wu, Q; Yu, S; Zou, Y | 1 |
Chai, X; Hu, H; Huang, T; Li, R; Li, X; Wu, M; Wu, Q; Yu, S; Zhao, Q; Zou, Y | 1 |
Gerwick, WH; Kurtán, T; Liu, B; Mándi, A; Sun, P; Tang, H; Wang, ZW; Xu, DX; Zhang, W | 1 |
Arul Antony, S; Balachandran, C; Shahavar Sulthana, S; Syed Shafi, S | 1 |
Kheylik, Y; Kondratov, I; Krasavin, M; Naumchyk, V; Platonov, M; Zahanich, I; Zozulya, S | 1 |
Bowlin, TL; Ding, X; Kwasny, SM; Nguyen, ST; Opperman, TJ; Peet, NP; Williams, JD | 1 |
Akdemir, A; Bizzarri, B; Bolasco, A; Caprara, F; Carradori, S; De Monte, C; Mari, E; Mollica, A; Rivanera, D; Secci, D; Zicari, A | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Chen, F; Di, H; Lan, L; Li, J; Lu, Y; Sheng, C; Wang, X; Wang, Y; Wei, H; Xiao, Q; Xu, Y; Zhang, L; Zhu, J | 1 |
Aktumsek, A; Bizzarri, B; Carradori, S; Chimenti, P; De Monte, C; Mari, E; Mollica, A; Rivanera, D; Secci, D; Zengin, G; Zicari, A | 1 |
Chen, F; Di, H; Lan, L; Li, J; Lu, Y; Wang, X; Wang, Y; Wei, H; Xiao, Q; Xu, Y; Zhang, L; Zhu, J | 1 |
Carazo, A; Drechslerová, M; Hrušková, ZR; Hyrsova, L; Kuneš, J; Nova, A; Pavek, P; Pour, M; Smutny, T; Špulák, M | 1 |
Kovalenko, A; Krasavin, M; Lukin, A; Moore, D; Tikhonova, IG; Zahanich, I; Zhurilo, N; Zozulya, S | 1 |
Cheng, M; Hao, C; Liu, C; Su, X; Sun, B; Wei, P; Zhang, X; Zhao, D; Zhao, L; Zhao, S | 1 |
Cai, Z; Ding, Z; Jiang, Y; Jin, Y; Li, R; Ni, T; Pang, L; Wang, T; Xie, F; Yu, S; Zhang, D; Zhao, J | 1 |
Cheng, M; Hao, C; Liu, C; Su, X; Wei, P; Wu, M; Zhang, X; Zhao, D; Zhao, L; Zhao, S | 1 |
Chen, F; Chen, W; Hu, L; Lan, L; Li, B; Li, J; Li, X; Lin, D; Liu, W; Liu, Y; Lu, Y; Mao, F; Ni, S; Qiu, X; Wang, M; Wei, H; Xu, Y; Zheng, X; Zhu, J | 1 |
Chen, F; Chen, W; Lan, L; Li, B; Li, J; Liu, Y; Mao, F; Ni, S; Wei, H; Zhu, J | 1 |
Benhamou, RI; Dorot, O; Elias, R; Fridman, M; Jaber, QZ; Oved, K; Pichinuk, E; Zada, SL | 1 |
Ancarani, F; Arzeni, D; Barchiesi, F; Branchesi, P; Crescenzi, G; Giacometti, A; Scalise, G | 1 |
Conteas, CN; Dretler, RH; Islam, MZ; Koster, FM; Laine, L; Sattler, F; Squires, K; Tuazon, C | 1 |
Breckenridge, A | 1 |
Gedde, S; Head, WS; O'Day, DM; Robinson, RD; Williams, TE | 1 |
Bodey, GP | 1 |
Wheat, LJ | 1 |
Denning, DW; Graybill, JR; Hanson, LH; Pappagianis, D; Rinaldi, MG; Sharkey, PK; Stevens, DA; Tucker, RM | 1 |
Baran, R | 1 |
Van Cutsem, J | 1 |
Viviani, MA | 1 |
Basugi, N; Eguchi, M; Matsuno, A; Yoshida, S | 1 |
Carbon, C; Eloy, O; Ghnassia, JC; Joly, V; Yeni, P | 1 |
Garg, AK; Hamir, Z; Padhye, AA; Sekhon, AS | 1 |
Lesher, JL | 1 |
Bava, AJ; Negroni, R | 1 |
Bender, HG; Laufer, B | 1 |
Büchner, T; Roos, N | 1 |
Lode, H; Schaberg, T | 1 |
Lozano, MC; Martín, E; Parras, P | 1 |
Adibzadeh, M; Friccius, H; Pawelec, G; Pohla, H; Schenk, A; Siegels-Hübenthal, P | 1 |
Konishi, H; Morita, K; Shimakawa, H | 1 |
Bennett, DE; Coleman, DC; Flint, SR; Gallagher, PJ; Henman, MC; Russell, RJ; Shanley, DB | 1 |
Chan, YF; Morris, B; Reddy, J; Woodgyer, A | 1 |
Dayer, P; Leemann, T | 1 |
Georgiev, VS | 1 |
Arena, V; Bresadola, M; Cipriani, P; Cirillo, L; Donadio, C; Ghezzi, C; Mazziotti, F; Pellizzari, G; Ragni, N | 1 |
Coker, RJ; Harris, JR; Main, J; Moulopoulos, D; Murphy, SM; Pinching, AJ | 1 |
Antonacci, B; Cacciapuoti, A; Hare, RS; Loebenberg, D; Menzel, F; Miller, GH; Moss, EL; Norris, C; Parmegiani, R; Yarosh-Tomaine, T | 1 |
Gibaldi, M | 2 |
Chandrasekar, PH; Edwards, DJ; Milad, MA; Touchette, MA | 1 |
Ehninger, G; Jaschonek, K; Pawelec, G; Rehbein, A; Schaudt, K | 1 |
Durmaz, B | 1 |
Lamey, PJ; Lewis, MA; Samaranyake, LP | 1 |
Ancarani, F; Arzeni, D; Barchiesi, F; Scalise, G | 1 |
Back, DJ; Tjia, JF | 1 |
Ehninger, G; Jaschonek, K; Pawelec, G | 1 |
Gerarden, T; Hollis, R; Isenberg, HD; Levenson, D; Pfaller, MA; Smith, MA; Tucci, CB | 1 |
Borowski, E; Mignini, F; Milewski, S | 1 |
Gentschew, G; Helm, EB; Just-Nübling, G; Meissner, K; Odewald, J; Staszewski, S; Stille, W | 1 |
Brettle, RP; Leen, CL; Milne, LJ; Russell, TB; Urquhart, D; Willocks, L | 1 |
Goto, S; Kawasaki, K; Matsumura, Y; Matsunaga, T; Ogawa, M; Tsuji, A | 1 |
Collett, MG; Henton, M; Lambrechts, N | 1 |
Fernandez, M; Zar, FA | 1 |
Costa, AR; Cucé, LC; dos Reis, VM; Lacaz, Cda S; Müller, H; Pegas, JR; Pires, MC; Porto, E; Rodrigues, MC | 1 |
Piérard, GE; Piérard-Franchimont, C; Rurangirwa, A | 1 |
Bianchi Porro, G; Cernuschi, M; Lazzarin, A; Parente, F; Rizzardini, G; Valsecchi, L | 1 |
Graybill, JR; Sharkey, PK | 1 |
Cauwenbergh, G; Heykants, J; Lavrijsen, K; Meuldermans, W; Van Peer, A; Woestenborghs, R | 1 |
Shindo, K | 1 |
Chafey, S; Franker, C; Hardy, WD; Lucatorto, FM | 1 |
Blum, RA; D'Andrea, DT; Florentino, BM; Gardner, MJ; Goldstein, H; Henry, EB; Hilligoss, DM; Schentag, JJ; Wilton, JH | 1 |
Dettori, G; Manzara, S; Morace, G | 1 |
Ellis, ME; Fox, R; Leen, CL; Mandal, BK; Neal, KR | 1 |
Harris, JR; Kitchen, VS; Savage, M | 1 |
Bercy, P; De Beule, F; Ferrant, A | 1 |
Brummer, E; Hanson, LH; Stevens, DA | 1 |
Bastide, JM; Mallié, M; Montès, B; Reynes, J | 1 |
Coker, DM; Kinghorn, GR; O'Mahony, C; Talbot, MD; Woolley, PD | 1 |
Ringel, SM | 1 |
Hector, RF; Yee, E | 1 |
Defaveri, J; Graybill, JR; Sun, SH | 1 |
Bailey, EM; Krakovsky, DJ; Rybak, MJ | 1 |
Linde, I; Mattie, H; Meynaar, I; Poell, R; Van 't Wout, JW; Van Furth, R | 1 |
Guinet, R; Marlier, H | 1 |
Larsen, RA | 1 |
Perfect, JR; Ritter, W; Wright, KA | 1 |
Meunier, F | 1 |
Ballard, SA; Ellis, SW; Kelly, SL; Troke, PF | 2 |
Mai, GT; McCormack, JG; Seow, WK; Thong, YH; Vuddhakul, V | 1 |
Mathiesen, LR; Thorsen, S | 1 |
Bottino, G; Menna, C | 1 |
Bergerat, JP; Dufour, P; Herbrecht, R; Koenig, H; Liu, KL; Maloisel, F; Oberling, F; Waller, J | 1 |
Kawasaki, K; Matsunaga, T; Uchida, K; Yamaguchi, H | 1 |
Dupont, B | 2 |
Mattie, H; van Furth, R; Van t Wout, JW | 1 |
Martin, MV | 1 |
Charuel, C; Latrille, F; Lodola, A | 1 |
Kobayashi, GS; Spitzer, ED | 1 |
Graybill, JR | 1 |
Goldberg, DJ; Green, ST; Kennedy, DH; McGuire, W; Nathwani, D | 1 |
Fransen, J; Janssen, PA; Van Cutsem, J; Van Gerven, F | 1 |
Warnock, DW | 1 |
Blancard, A; Goudard, M; Mary, C; Quilici, M; Regli, P | 1 |
Bligh, HF; Kelly, SL; Kenna, S; Watson, PF | 1 |
Ehninger, G; Einsele, H; Jaschonek, K; Roth, HJ; Steinhilber, D | 1 |
Coussement, W; De Coster, R; Lampo, A; Marsboom, R; Van Cauteren, H; Vandenberghe, J; Vanparys, P | 1 |
Clumeck, N; De Wit, S; Goossens, H; Weerts, D | 1 |
Polak, A | 1 |
Houston, JB; Humphrey, MJ; Matthew, DE; Tarbit, MH | 1 |
Dismukes, WE; Saag, MS | 1 |
Walsh, TJ | 1 |
Beggs, WH; Bennett, RL; Hughes, CE; Tuna, IC | 1 |
Senior, DS; Shaw, JT | 1 |
Abadie, SM; Greer, DL; Noel, SB; Pankey, GA; Zachary, JA | 1 |
Dismukes, WE | 1 |
Hanger, DP; Jevons, S; Shaw, JT | 1 |
Coulaud, JP; Ngo Van, P | 1 |
Drew, RH; Gallis, HA; Perfect, JR | 1 |
Pizzo, A; Walsh, TJ | 1 |
Gordon, MA; Lapa, EW; Passero, PG | 1 |
Beach, DH; Goad, LJ; Holz, GG | 1 |
Bähr, V; Eckhoff, C; Oelkers, W | 1 |
Odds, FC; Webster, CE | 1 |
Faergemann, J | 1 |
Brammer, KW; Feczko, JM | 1 |
Hay, RJ | 2 |
Stevens, DA | 1 |
Brammer, KW; Kutzer, E; Leodolter, S; Oittner, R | 1 |
Brammer, KW; Marriott, MS; Richardson, K; Troke, PF | 1 |
Durack, DT; Perfect, JR | 1 |
Andrews, RJ; Brammer, KW; Marriott, MS; Richardson, K; Troke, PF | 1 |
Durack, DT; Perfect, JR; Savani, DV | 1 |
Ahrens, J; Graybill, JR; Sun, SH | 1 |
Hopwood, V; Johnson, EM; Kennedy, CT; Smith, KJ; Van Cutsem, J; Vanden Bossche, H; Warnock, DW | 1 |
Graybill, JR; Palou de Fernandez, E; Patino, MM; Tarbit, MH | 1 |
Ahrens, J; Graybill, JR; Palou, E | 1 |
Galgiani, JN; Rogers, TE | 1 |
Cobo, LM; Durack, DT; Perfect, JR; Savani, DV | 1 |
Beggs, WH; Hughes, CE | 1 |
Dixon, DM; Polak, A | 1 |
Andrews, RJ; Marriott, MS; Richardson, K; Troke, PF | 1 |
Abruzzo, GK; Fromtling, RA; Giltinan, DM; Turnbull, TA | 1 |
Asgari, M; Back, DJ | 1 |
Wenig, JA | 1 |
Just-Nübling, G | 1 |
Staben, C | 1 |
Baldwin, BC; Corran, A; Kelly, SL; Kwon-Chung, J; Lamb, DC | 1 |
Hahn, K; Scheven, Ch; Scheven, M; Senf, A | 1 |
Denning, DW | 1 |
Hoeprich, PD | 1 |
Ahearn, DG; Kalya, AV | 1 |
Bernhardt, R; Denner, K; Doehmer, J; Schmalix, W; Vogel, R | 1 |
Force, RW; Nahata, MC | 1 |
Cross, JT; Hickerson, SL; Yamauchi, T | 1 |
Barchiesi, F; Colombo, AL; McGough, DA; Rinaldi, MG | 1 |
Johnson, EM; Luker, J; Porter, SR; Scully, C; Warnock, DW | 1 |
Denning, DW; Law, D; Mason, C; Moore, CB; Wardle, HM | 1 |
Belcher, KE; Law, EJ; Spencer, SA; Still, JM | 1 |
Andreu, A; Arévalo, MP; Arias, A; Rodríguez, C; Sierra, A | 1 |
Acosta, D; Rodriguez, RJ | 2 |
Greenspan, D | 1 |
Wheat, J | 1 |
Kivistö, KT; Klotz, U; Neuvonen, PJ | 1 |
Ancarani, F; Arzeni, D; Barchiesi, F; Del Poeta, M; Marinucci, G; Morbiducci, V; Scalise, G | 1 |
Bartlett, MS; Queener, SF; Richardson, JD; Shaw, MM; Smith, JW | 1 |
Galimberti, R; Robles-Soto, M; Stengel, F; Suchil, P | 1 |
Dubé, MP; Evans, S; Heseltine, PN; Rinaldi, MG; Zawacki, B | 1 |
Hernández-Sampelayo, T | 1 |
DeDoncker, PR; Degreef, HJ | 1 |
Roberts, DT | 1 |
Bickers, DR | 1 |
al Khayat, R; Courdavault, L; Michel, C; Mignon, F; Roux, P; Viron, B | 1 |
Aoki, Y; Arisawa, M; Kondoh, M; Nakamura, Y; Nakayama, N; Yoshihara, F | 1 |
Antinori, S; Ardizzone, S; Bianchi Porro, G; Cernuschi, M; Esposito, R; Lazzarin, A; Moroni, M; Parente, F | 1 |
Cantilena, LR; Honig, PK | 1 |
Bailey, CJ; Cartledge, JM; Morris, SA | 1 |
Arendorf, TM; van der Bijl, P | 1 |
Edwards, JE; Filler, SG; Swerdloff, JN | 1 |
Dodd, CL; Greenspan, D; Heinic, GS; Hollander, H; MacPhail, LA; Stevens, DA; Stringari, S; Strull, WM | 1 |
Drew, RH | 1 |
Baciewicz, AM; Baciewicz, FA | 1 |
Neely, D | 1 |
Sangueza, OP; Shupack, JL; Stiller, MJ | 1 |
Acuña, G; Brengues, C; Cuny, G; Labarca, J; Muñoz, S; Oddó, D; Saavedra, H; Sepúlveda, C; Solari, A; Veas, F | 1 |
Johnson, EM; Warnock, DW; White, DJ | 1 |
Fetchick, R; Graybill, JR; Sharkey-Mathis, PK; Velez, J | 1 |
Klauss, V; Lund, OE; Miño de Kaspar, H | 1 |
Degreef, H | 1 |
Bolzonella, R; Contestabile, A; Fabris, A; Gardin, C; Pellanda, MV | 1 |
Brossier, KA; Goldschmidt, RH; Legg, JJ | 1 |
Rutledge, TM; Thio, CL | 1 |
Catalin, J; Durand, A; Lacarelle, B; Rajaonarison, JF; Sampol, E | 1 |
Johnson, EM; Warnock, DW | 1 |
Kalhorn, TF; Kharasch, ED; Mitra, AK; Slattery, JT; Thummel, KE; Unadkat, JD | 1 |
Cunha, BA; Klein, NC | 1 |
Chen, SC; Gilbert, GL; Gordon, S; O'Donnell, ML | 1 |
Brennan, B; Ervine, CM; Houston, JB; Matthew, DE | 1 |
Bolmström, A; Messer, SA; Odds, FC; Pfaller, MA; Rex, JH | 1 |
Abruzzo, GK; Bartizal, K; Flattery, AM; Gill, CJ; Smith, JG | 1 |
Clark, FS; Gow, NA; Hitchcock, CA; Parkinson, T | 1 |
Boyvat, A; Geilen, CC; Orfanos, CE; Seibold, M; Tebbe, B; Wölfer, LU | 1 |
Gill, HJ; Madden, S; Maggs, JL; Park, BK; Pirmohamed, M | 1 |
Caldarola, G; Cauda, R; Morace, G; Ortona, L; Posteraro, B; Tacconelli, E; Tumbarello, M | 1 |
Bunting, P; Finlay, R; Richardson, C; Taylor, CB; Welch, J | 1 |
Moreno, MI; Zaror, L | 1 |
Goldman, M; Lee, YP | 1 |
Cao, B; Samaranayake, LP; Tsang, DN; Tsang, PW; Wang, J | 1 |
Friedman, HL; Greenblatt, DJ; Karsov, D; Schmider, J; Shader, RI; Vena, R; von Moltke, LL | 1 |
Baldwin, BC; Corran, AJ; Kelly, DE; Kelly, SL; Lamb, DC | 1 |
Kelly, DE; Kelly, SL; Lamb, DC; Manning, NJ | 1 |
Cuenca, M; Gadea, I; Gegúndez, MI; Soriano, F; Valero, ML; Zapardiel, J | 1 |
Gøtzsche, PC; Johansen, HK | 1 |
McDonald, JA; Saulsbury, FT | 1 |
Carver, PL; Kauffman, CA | 1 |
Baily, GG; Denning, DW; Hood, SV | 1 |
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Sun, B; Sun, N; Sun, Y; Tian, L; Zhao, D; Zhao, L; Zhao, S | 1 |
Braga, SS | 1 |
Gao, F; Huang, G; Xiao, J | 1 |
Jaisingh, A; Maurya, IK; Salunke, DB; Singh, R | 1 |
Billamboz, M; Dascalu, AE; Fayeulle, A; Furman, C; Ghinet, A; Lipka, E; Rigo, B | 1 |
Cheng, M; Su, X; Sun, N; Sun, Y; Tian, L; Yin, W; Zhang, C; Zhao, D; Zhao, L; Zhao, S; Zheng, Y | 1 |
Cheng, M; Cui, H; Jiang, H; Li, S; Liu, L; Su, X; Sun, Y; Wu, T; Yin, W; Zhang, Y; Zhao, D; Zhao, L; Zheng, Y | 1 |
Guengerich, FP; Hargrove, TY; Lepesheva, GI; Nes, WD; Rachakonda, G; Villalta, F; Wawrzak, Z | 1 |
Emami, S; Ghobadi, E; Saednia, S | 1 |
Han, J; Liu, M; Liu, W; Liu, Y; Sun, B; Wang, Q; Yu, S | 1 |
102 review(s) available for fluconazole and ketoconazole
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Clinical significance of interactions with antifungal agents.
Topics: Antifungal Agents; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Fluconazole; Humans; Itraconazole; Ketoconazole | 1992 |
Azole antifungal agents.
Topics: Animals; Antifungal Agents; Azoles; Fluconazole; Humans; Itraconazole; Ketoconazole; Miconazole; Mycoses | 1992 |
Histoplasmosis in Indianapolis.
Topics: Amphotericin B; Disease Outbreaks; Fluconazole; Histoplasmosis; Humans; Indiana; Itraconazole; Ketoconazole | 1992 |
[Choice and monitoring of the treatment of systemic mycoses. Value and limitations of in vitro tests].
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Therapy, Combination; Fluconazole; Flucytosine; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Opportunistic Infections | 1992 |
[Current developments in antimycotic therapy in gynecology and obstetrics].
Topics: Animals; Antifungal Agents; Candidiasis, Vulvovaginal; Dose-Response Relationship, Drug; Female; Fluconazole; Humans; Infant, Newborn; Itraconazole; Ketoconazole; Mycoses; Pregnancy; Pregnancy Complications, Infectious | 1992 |
Antifungal treatment strategy in leukemia patients.
Topics: Amphotericin B; Antifungal Agents; Drug Therapy, Combination; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Leukemia; Mycoses; Tomography, X-Ray Computed | 1992 |
[Therapy of pulmonary mycoses].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Blastomycosis; Coccidioidomycosis; Cryptococcosis; Fluconazole; Flucytosine; Histoplasmosis; Humans; Itraconazole; Ketoconazole; Lung Diseases, Fungal | 1992 |
Treatment and developmental therapeutics in aspergillosis. 2. Azoles and other antifungal drugs.
Topics: Animals; Antifungal Agents; Aspergillosis; Aspergillosis, Allergic Bronchopulmonary; Azoles; Clotrimazole; Disease Models, Animal; Fluconazole; Humans; Imidazoles; Ketoconazole; Lung Diseases, Fungal; Miconazole; Otitis Externa | 1992 |
[Comparative clinical study of a new imidazole molecule (fluconazole) and ketaconazole in the treatment of Candida albicans vulvovaginitis].
Topics: Adult; Candidiasis, Vulvovaginal; Drug Evaluation; Female; Fluconazole; Humans; Ketoconazole; Middle Aged | 1992 |
Drug interactions: Part I.
Topics: Antidepressive Agents, Tricyclic; Caffeine; Cimetidine; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Fluconazole; Fluoxetine; Hexobarbital; Humans; Ketoconazole; Nimodipine; Oxidoreductases; Pharmaceutical Preparations; Rifampin; Stereoisomerism; Warfarin; Zidovudine | 1992 |
Drug interactions: part II.
Topics: Amiodarone; Biological Availability; Dapsone; Didanosine; Drug Interactions; Fluconazole; Food; Humans; Intestinal Absorption; Ketoconazole; Pharmaceutical Preparations; Rifampin | 1992 |
[Importance of the new triazoles in antifungal therapy].
Topics: Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses | 1991 |
Diagnosis and treatment of oral candidosis.
Topics: Antifungal Agents; Candidiasis, Oral; Chronic Disease; Fluconazole; HIV Infections; Humans; Immune Tolerance; Itraconazole; Ketoconazole; Opportunistic Infections | 1991 |
Laboratory monitoring of antifungal chemotherapy. British Society for Antimicrobial Chemotherapy Working Party.
Topics: Adult; Amphotericin B; Antifungal Agents; Chromatography, High Pressure Liquid; Drug Resistance; Drug Therapy, Combination; Fluconazole; Flucytosine; Humans; Immunodiffusion; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses | 1991 |
Fungal infections and their management.
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses; Naphthalenes; Terbinafine; Triazoles | 1990 |
Pharmacokinetics of oral antifungals and their clinical implications.
Topics: Absorption; Administration, Oral; Animals; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Tissue Distribution | 1990 |
Fluconazole and itraconazole for vulvo-vaginal candidosis.
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Itraconazole; Ketoconazole | 1990 |
New antifungal agents for the systemic mycoses.
Topics: Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Molecular Structure; Mycoses | 1990 |
The triazole antifungal agents: a review of itraconazole and fluconazole.
Topics: Antifungal Agents; Aspergillus; Candida albicans; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cryptococcus neoformans; Fluconazole; Half-Life; Humans; Itraconazole; Ketoconazole; Metabolic Clearance Rate | 1990 |
Azoles and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Antifungal Agents; Azoles; Fluconazole; Humans; Itraconazole; Ketoconazole; Meningitis; Mycoses; Opportunistic Infections | 1990 |
[Systemic mycotic infections].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses | 1990 |
Testing of organisms for susceptibility to triazoles: is it justified?
Topics: Antifungal Agents; Drug Resistance, Microbial; Fluconazole; Fungi; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Triazoles | 1989 |
New antifungal agents.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Azoles; Echinocandins; Fluconazole; Fungi; Humans; Itraconazole; Ketoconazole; Mycoses; Peptides; Peptides, Cyclic; Triazoles | 1989 |
Itraconazole and fluconazole: new drugs for deep fungal infection.
Topics: Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses | 1989 |
Toxicological profile and safety evaluation of antifungal azole derivatives.
Topics: Abnormalities, Drug-Induced; Animals; Antifungal Agents; Endocrine Glands; Fluconazole; Humans; Itraconazole; Ketoconazole; Liver | 1989 |
Azole antifungal agents: emphasis on new triazoles.
Topics: Animals; Antifungal Agents; Chemical Phenomena; Chemistry; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses; Triazoles | 1988 |
Recent advances in the treatment of systemic fungal infections.
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Antifungal Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Mycoses; Triazoles | 1987 |
Azole antifungal drugs: old and new.
Topics: Animals; Antifungal Agents; Azoles; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Triazoles | 1988 |
Treatment of systemic fungal infections: recent progress and current problems.
Topics: Amphotericin B; Antifungal Agents; Chemical Phenomena; Chemistry; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Mycoses; Triazoles | 1988 |
New oral treatments for dermatophytosis.
Topics: Administration, Oral; Antifungal Agents; Dermatomycoses; Fluconazole; Itraconazole; Ketoconazole; Naphthalenes; Terbinafine; Triazoles | 1988 |
The systemic treatment of onychomycosis.
Topics: Administration, Oral; Antifungal Agents; Fluconazole; Foot Dermatoses; Griseofulvin; Humans; Itraconazole; Ketoconazole; Naphthalenes; Onychomycosis; Terbinafine | 1995 |
[Therapy of candidiasis and cryptococcosis in AIDS].
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis; Candidiasis, Oral; Cryptococcosis; Fluconazole; Humans; Itraconazole; Ketoconazole | 1994 |
Can we prevent azole resistance in fungi?
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Azoles; Candida; Candidiasis; Drug Resistance, Microbial; Fluconazole; Humans; Itraconazole; Ketoconazole | 1995 |
Antifungal chemotherapy.
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Morpholines; Naphthalenes; Terbinafine | 1995 |
Antifungal drugs.
Topics: Amphotericin B; Antifungal Agents; Child; Child, Preschool; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses | 1995 |
Treatment of oropharyngeal candidiasis in HIV-positive patients.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Candidiasis, Oral; CD4-Positive T-Lymphocytes; Clotrimazole; Fluconazole; HIV Infections; Humans; Ketoconazole; Leukocyte Count; Nystatin; Risk Factors | 1994 |
Histoplasmosis: recognition and treatment.
Topics: Amphotericin B; Fluconazole; Histoplasmosis; Humans; Itraconazole; Ketoconazole; Serologic Tests | 1994 |
Inhibition of terfenadine metabolism. Pharmacokinetic and pharmacodynamic consequences.
Topics: Cytochrome P-450 Enzyme System; Drug Interactions; Fluconazole; Heart; Humans; Itraconazole; Ketoconazole; Prodrugs; Terfenadine | 1994 |
Current therapy of dermatophytosis.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Administration, Topical; Allylamine; Antifungal Agents; Dermatomycoses; Drug Administration Schedule; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Morpholines; Time Factors; Tolnaftate | 1994 |
Oral therapeutic agents in fungal nail disease.
Topics: Administration, Oral; Allylamine; Antifungal Agents; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Onychomycosis; Terbinafine; Time Factors; Treatment Outcome | 1994 |
Antifungal therapy: potential interactions with other classes of drugs.
Topics: Amphotericin B; Antifungal Agents; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Fluconazole; Flucytosine; Griseofulvin; Humans; Itraconazole; Ketoconazole; Mycoses | 1994 |
Fungal peritonitis in patients on peritoneal dialysis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antifungal Agents; Candidiasis; Drug Administration Routes; Drug Therapy, Combination; Female; Fluconazole; Flucytosine; Humans; Ketoconazole; Kidney Failure, Chronic; Length of Stay; Male; Middle Aged; Mycoses; Peritoneal Dialysis; Peritonitis; Risk Factors; Treatment Outcome | 1994 |
Itraconazole and fluconazole in oropharyngeal candidiasis.
Topics: Antifungal Agents; Candidiasis; Candidiasis, Oral; Fluconazole; Humans; Itraconazole; Ketoconazole; Pharyngeal Diseases | 1993 |
Pharmacotherapy of disseminated histoplasmosis in patients with AIDS.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Clinical Trials as Topic; Fluconazole; Histoplasmosis; Humans; Itraconazole; Ketoconazole; United States | 1993 |
Ketoconazole and fluconazole drug interactions.
Topics: Drug Interactions; Fluconazole; Humans; Ketoconazole | 1993 |
Systemic drugs in the treatment of dermatophytoses.
Topics: Antifungal Agents; Dermatomycoses; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Molecular Structure | 1993 |
Onychomycosis. Agents of choice.
Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Candidiasis, Cutaneous; Fluconazole; Foot Dermatoses; Griseofulvin; Hand Dermatoses; Humans; Itraconazole; Ketoconazole; Naphthalenes; Onychomycosis; Terbinafine | 1993 |
[New antifungal agents in the treatment of superficial dermatomycoses].
Topics: Administration, Topical; Antifungal Agents; Azoles; Dermatomycoses; Fluconazole; Humans; Itraconazole; Ketoconazole; Naphthalenes; Terbinafine; Tolnaftate | 1993 |
New antifungal drugs for pulmonary mycoses.
Topics: Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Lung Diseases, Fungal | 1996 |
The role of azole antifungal agents for systemic antifungal therapy.
Topics: Amphotericin B; Antifungal Agents; Drug Costs; Drug Interactions; Drug Resistance, Microbial; Fluconazole; Humans; Itraconazole; Ketoconazole | 1997 |
Meta-analysis of prophylactic or empirical antifungal treatment versus placebo or no treatment in patients with cancer complicated by neutropenia.
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Miconazole; Mycoses; Neoplasms; Neutropenia; Randomized Controlled Trials as Topic | 1997 |
Use of azoles for systemic antifungal therapy.
Topics: Antifungal Agents; Drug Interactions; Drug Resistance, Microbial; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Mycoses; Triazoles | 1997 |
Azole resistance in Candida.
Topics: Antifungal Agents; Azoles; Candidiasis; Drug Resistance, Microbial; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Mucous Membrane | 1997 |
Current trends in onychomycosis therapy: a literature review.
Topics: Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Naphthalenes; Onychomycosis; Terbinafine | 1997 |
[Prevention and treatment of invasive mycoses in patients with neutropenia and bone marrow transplantation].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Bone Marrow Transplantation; Candidiasis; Candidiasis, Chronic Mucocutaneous; Clinical Trials as Topic; Cryptococcosis; Double-Blind Method; Fluconazole; Humans; Itraconazole; Ketoconazole; Mucormycosis; Mycoses; Neutropenia; Nystatin; Primary Prevention; Recurrence; Retrospective Studies | 1995 |
[Prevention and treatment of fungal infections in solid-organ transplant recipients].
Topics: Amphotericin B; Antifungal Agents; Clinical Trials as Topic; Fluconazole; Heart Transplantation; Humans; Itraconazole; Ketoconazole; Kidney Transplantation; Liver Transplantation; Lung Transplantation; Multicenter Studies as Topic; Mycoses; Pancreas Transplantation; Risk Factors; Transplantation | 1995 |
[Diagnosis, treatment and prevention of infections caused by fungi in HIV-positive patients].
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Aspergillosis; Candidiasis; Candidiasis, Oral; Candidiasis, Vulvovaginal; Child; Clinical Trials as Topic; Cryptococcosis; Drug Resistance, Microbial; Esophageal Diseases; Female; Fluconazole; Fungi; Humans; Ketoconazole; Male; Retrospective Studies | 1995 |
[Superficial mycoses in immunosuppressed patients].
Topics: Adult; Antifungal Agents; Candidiasis, Cutaneous; Candidiasis, Oral; Candidiasis, Vulvovaginal; Child; Dermatitis, Seborrheic; Dermatomycoses; Female; Fluconazole; Humans; Imidazoles; Immunosuppression Therapy; Itraconazole; Ketoconazole; Male; Morpholines; Onychomycosis; Tinea; Tinea Versicolor; Transplantation; Triazoles | 1995 |
[Antifungal agent resistance of yeasts of clinical significance].
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Azoles; Candida albicans; Candidiasis; Drug Resistance, Microbial; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses; Yeasts | 1995 |
[Commonly used antifungal agents in the treatment of systemic mycoses].
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Clinical Trials as Topic; Coccidioidomycosis; Cryptococcosis; Fluconazole; Flucytosine; Hematologic Diseases; Histoplasmosis; Humans; Itraconazole; Ketoconazole; Kidney; Mycoses; Thrombophlebitis | 1995 |
Onychomycosis: pathogenesis, diagnosis, and management.
Topics: Adult; Antifungal Agents; Child; Diagnosis, Differential; Female; Fluconazole; Foot Dermatoses; Hand Dermatoses; Humans; Itraconazole; Ketoconazole; Male; Nails; Naphthalenes; Onychomycosis; Terbinafine | 1998 |
Antifungal agents. Part II. The azoles.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Azoles; Drug Interactions; Fluconazole; Humans; Immunocompromised Host; Itraconazole; Ketoconazole | 1999 |
Dermatophyte infections in children.
Topics: Antifungal Agents; Arthrodermataceae; Child; Child, Preschool; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Microsporum; Naphthalenes; Terbinafine; Tinea; Trichophyton | 1999 |
Treatment of recurrent vulvovaginal candidiasis.
Topics: Antifungal Agents; Boric Acids; Candidiasis, Vulvovaginal; Clotrimazole; Drug Interactions; Female; Fluconazole; Humans; Ketoconazole; Patient Education as Topic; Recurrence; Risk Factors; Teaching Materials; Time Factors; Triazoles | 2000 |
An evaluation of intermittent therapies used to treat onychomycosis and other dermatomycoses with the oral antifungal agents.
Topics: Administration, Oral; Antifungal Agents; Clinical Trials as Topic; Dermatomycoses; Drug Administration Schedule; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Naphthalenes; Onychomycosis; Terbinafine | 2000 |
The treatment of dermatophytosis: safety considerations.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Dermatomycoses; Fluconazole; Humans; Itraconazole; Ketoconazole; Naphthalenes; Terbinafine | 2000 |
Antimycotic agents in oral candidosis: an overview: 2. Treatment of oral candidosis.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis, Oral; Clotrimazole; Drug Interactions; Drug Resistance, Microbial; Fluconazole; Humans; Itraconazole; Ketoconazole; Miconazole; Nystatin; Virulence | 2000 |
A systematic review of the effectiveness of antifungal drugs for the prevention and treatment of oropharyngeal candidiasis in HIV-positive patients.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Candidiasis; Candidiasis, Oral; Clotrimazole; Databases as Topic; Fluconazole; HIV Seropositivity; Humans; Itraconazole; Ketoconazole; Nystatin; Oropharynx; Pharyngeal Diseases; Randomized Controlled Trials as Topic; Research Design; Statistics as Topic; Treatment Outcome | 2001 |
A plea to bridge the gap between antifungals and the management of onychomycosis.
Topics: Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Naphthalenes; Onychomycosis; Terbinafine | 2001 |
Oral candidal infections and antimycotics.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Anti-Infective Agents, Local; Antifungal Agents; Candida; Candidiasis, Oral; Chlorhexidine; Clotrimazole; Drug Resistance, Fungal; Fluconazole; Flucytosine; Humans; Immunocompromised Host; Itraconazole; Ketoconazole; Miconazole; Mouth; Nystatin; Opportunistic Infections; Saliva; Treatment Failure; Triazoles | 2000 |
Antifungal agents of use in animal health--chemical, biochemical and pharmacological aspects.
Topics: Animals; Antifungal Agents; Clotrimazole; Drug Resistance, Fungal; Econazole; Fluconazole; Flucytosine; Griseofulvin; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Naphthalenes; Natamycin; Nystatin; Terbinafine; Thiabendazole; Tolnaftate; Veterinary Drugs | 2003 |
Framing the future of antifungals in atopic dermatitis.
Topics: Antifungal Agents; Dermatitis, Atopic; Fluconazole; Forecasting; Humans; Itraconazole; Ketoconazole; Treatment Outcome | 2003 |
The use of oral antifungal agents to treat onychomycosis.
Topics: Administration, Oral; Antifungal Agents; Drug Interactions; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Naphthalenes; Onychomycosis; Terbinafine | 2003 |
[Therapeutic safety of antimycotics in the treatment of systemic fungal infections].
Topics: Amphotericin B; Antifungal Agents; Drug Interactions; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Liver; Mycoses | 2003 |
Antifungal pharmacotherapy for neonatal candidiasis.
Topics: Amphotericin B; Antifungal Agents; Candidiasis; Caspofungin; Cross Infection; Echinocandins; Fluconazole; Flucytosine; Fungal Proteins; Fungemia; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Ketoconazole; Lipopeptides; Peptides; Peptides, Cyclic; Pyrimidines; Triazoles; Voriconazole | 2003 |
History of the development of azole derivatives.
Topics: Antifungal Agents; Azoles; Drug Resistance, Fungal; Fluconazole; Itraconazole; Ketoconazole; Pyrimidines; Triazoles; Voriconazole | 2004 |
Candidiasis (vulvovaginal).
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Male; Nystatin; Sexual Partners | 2003 |
Candidiasis (vulvovaginal).
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Male; Nystatin; Secondary Prevention; Sexual Partners | 2003 |
Pharmacological management of paracoccidioidomycosis.
Topics: Amphotericin B; Central Nervous System Fungal Infections; Drug Resistance; Fluconazole; Follow-Up Studies; Humans; Immunocompromised Host; Itraconazole; Ketoconazole; Paracoccidioidomycosis; Pyrimidines; Sulfonamides; Triazoles; Voriconazole | 2005 |
Phaeohyphomycosis in Korea.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Child; Dermatomycoses; Exophiala; Female; Fluconazole; Humans; Hyphae; Itraconazole; Ketoconazole; Male; Middle Aged; Subcutaneous Tissue | 2005 |
[Drug-drug interaction of antifungal drugs].
Topics: Antifungal Agents; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Echinocandins; Fluconazole; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Lipopeptides; Lipoproteins; Micafungin; Miconazole; Microsomes, Liver; Peptides, Cyclic; Pyrimidines; Triazoles; Voriconazole | 2005 |
Clinical status of agents being developed for leishmaniasis.
Topics: Aminoquinolines; Antiprotozoal Agents; Fluconazole; Humans; Imiquimod; Ketoconazole; Leishmaniasis; Paromomycin; Phosphorylcholine | 2005 |
An overview of antifungal drugs and their use for treatment of deep and superficial mycoses in animals.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillus; Candida; Fluconazole; Griseofulvin; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Severity of Illness Index | 2005 |
Antifungal agents for preventing fungal infections in non-neutropenic critically ill and surgical patients: systematic review and meta-analysis of randomized clinical trials.
Topics: Adult; Antifungal Agents; Critical Illness; Fluconazole; Humans; Immunocompromised Host; Incidence; Ketoconazole; Mycoses; Randomized Controlled Trials as Topic | 2006 |
Fungal nail infections.
Topics: Antifungal Agents; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Naphthalenes; Onychomycosis; Terbinafine | 2005 |
Candidiasis (vulvovaginal).
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Nystatin; Secondary Prevention | 2005 |
Fungal toenail infections.
Topics: Antifungal Agents; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Naphthalenes; Onychomycosis; Terbinafine | 2006 |
Effective treatment for dermatophytoses of the foot: effect on restoration of depressed cell-mediated immunity.
Topics: Animals; Antifungal Agents; Fluconazole; Foot Dermatoses; Humans; Immunity, Cellular; Itraconazole; Ketoconazole; Mycoses; Naphthalenes; Terbinafine | 2007 |
[Prophylactic antifungal treatment in critically ill patients. A survey of a Cochrane review].
Topics: Adult; Antifungal Agents; Critical Illness; Evidence-Based Medicine; Fluconazole; Humans; Immunocompromised Host; Ketoconazole; Mycoses | 2008 |
Spondylodiscitis due to an emergent fungal pathogen: Blastoschizomyces capitatus, a case report and review of the literature.
Topics: Aged; Amphotericin B; Antifungal Agents; Dipodascus; Discitis; Fluconazole; Humans; Itraconazole; Ketoconazole; Lumbar Vertebrae; Male; Microbial Sensitivity Tests; Naphthalenes; Opportunistic Infections; Radiography; Terbinafine; Treatment Outcome | 2009 |
Conazoles.
Topics: Antifungal Agents; Fluconazole; Itraconazole; Ketoconazole; Miconazole; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Triazoles; Voriconazole | 2010 |
Systemic antifungal therapy for tinea capitis in children.
Topics: Antifungal Agents; Child; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Naphthalenes; Randomized Controlled Trials as Topic; Terbinafine; Tinea Capitis | 2016 |
Tinea capitis in children: a systematic review of management.
Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Child; Drug Therapy, Combination; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Microsporum; Specimen Handling; Terbinafine; Tinea Capitis; Trichophyton | 2018 |
Cutaneous candidiasis - an evidence-based review of topical and systemic treatments to inform clinical practice.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Candidiasis, Cutaneous; Clotrimazole; Drug Therapy, Combination; Evidence-Based Medicine; Fluconazole; Humans; Ketoconazole; Miconazole; Nystatin | 2019 |
The function of adrenal glands in children and adolescents during and after oncological treatment.
Topics: Adolescent; Adrenal Glands; Child; Etomidate; Fluconazole; Humans; Hypothalamo-Hypophyseal System; Immune Checkpoint Inhibitors; Ketoconazole; Metyrapone; Mitotane; Pituitary-Adrenal System; Quality of Life | 2022 |
An overview of azoles targeting sterol 14α-demethylase for antileishmanial therapy.
Topics: 14-alpha Demethylase Inhibitors; Antiprotozoal Agents; Azoles; Humans; Leishmania; Molecular Structure; Sterol 14-Demethylase | 2017 |
Tetrazole hybrids and their antifungal activities.
Topics: Animals; Antifungal Agents; Azoles; Fungi; Humans; Mycoses; Pyridines; Pyrimidines; Quinolines; Structure-Activity Relationship; Tetrazoles | 2019 |
Strategies for the development of highly selective cytochrome P450 inhibitors: Several CYP targets in current research.
Topics: Animals; Binding Sites; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Development; Heme; Humans; Hydrophobic and Hydrophilic Interactions; Protein Binding | 2019 |
Multi-target drugs active against leishmaniasis: A paradigm of drug repurposing.
Topics: Amphotericin B; Antifungal Agents; Drug Repositioning; Drug Resistance, Fungal; Fluconazole; Humans; Itraconazole; Leishmaniasis; Molecular Targeted Therapy; Phosphorylcholine; Sterol 14-Demethylase; Triazoles; Voriconazole | 2019 |
Current scenario of tetrazole hybrids for antibacterial activity.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Tetrazoles | 2019 |
Synthetic approaches and structural diversity of triazolylbutanols derived from voriconazole in the antifungal drug development.
Topics: Antifungal Agents; Drug Development; Fungi; Voriconazole | 2022 |
36 trial(s) available for fluconazole and ketoconazole
Article | Year |
---|---|
Fluconazole compared with ketoconazole for the treatment of Candida esophagitis in AIDS. A randomized trial.
Topics: Acquired Immunodeficiency Syndrome; Adult; Candidiasis; Double-Blind Method; Esophagitis; Esophagoscopy; Female; Fluconazole; Humans; Ketoconazole; Male | 1992 |
Opportunistic fungal infections in patients with acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Antifungal Agents; Candidiasis; Cryptococcosis; Double-Blind Method; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses; Opportunistic Infections; Oropharynx; Pilot Projects | 1992 |
[Comparative clinical study of a new imidazole molecule (fluconazole) and ketaconazole in the treatment of Candida albicans vulvovaginitis].
Topics: Adult; Candidiasis, Vulvovaginal; Drug Evaluation; Female; Fluconazole; Humans; Ketoconazole; Middle Aged | 1992 |
Contrasting effects of fluconazole and ketoconazole on phenytoin and testosterone disposition in man.
Topics: Administration, Oral; Adult; Fluconazole; Humans; Ketoconazole; Male; Phenytoin; Random Allocation; Testosterone | 1992 |
Fluconazole prophylaxis of recurrent oral candidiasis in HIV-positive patients.
Topics: Acquired Immunodeficiency Syndrome; Candidiasis, Oral; Chronic Disease; Drug Administration Schedule; Fluconazole; HIV Infections; Humans; Ketoconazole; Recurrence | 1991 |
Increased gastric pH and the bioavailability of fluconazole and ketoconazole.
Topics: Adult; Biological Availability; Cimetidine; Drug Interactions; Fluconazole; Gastric Acidity Determination; Humans; Ketoconazole; Male; Random Allocation; Statistics as Topic | 1991 |
The triazole antifungal agents: a review of itraconazole and fluconazole.
Topics: Antifungal Agents; Aspergillus; Candida albicans; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Cryptococcus neoformans; Fluconazole; Half-Life; Humans; Itraconazole; Ketoconazole; Metabolic Clearance Rate | 1990 |
Comparison of fluconazole and ketoconazole for oropharyngeal candidiasis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Aged; AIDS-Related Complex; Candidiasis, Oral; Clinical Trials as Topic; Double-Blind Method; Female; Fluconazole; Follow-Up Studies; Humans; Ketoconazole; Male; Middle Aged; Oropharynx; Pharyngeal Diseases; Prospective Studies; Recurrence; Triazoles | 1989 |
Fluconazole and testosterone: in vivo and in vitro studies.
Topics: Adult; Analysis of Variance; Animals; Antifungal Agents; Cells, Cultured; Double-Blind Method; Fluconazole; Humans; Ketoconazole; Leydig Cells; Male; Rats; Testosterone; Triazoles | 1988 |
Single-dose oral fluconazole in the treatment of vaginal candidosis.
Topics: Administration, Oral; Administration, Topical; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Female; Fluconazole; Humans; Ketoconazole; Triazoles | 1988 |
A comparison of fluconazole and ketoconazole in the oral treatment of vaginal candidiasis; report of a double-blind multicentre trial.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antifungal Agents; Candidiasis, Vulvovaginal; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Female; Fluconazole; Humans; Ketoconazole; Middle Aged; Multicenter Studies as Topic; Random Allocation; Recurrence; Triazoles | 1988 |
Salivary concentrations of ketoconazole and fluconazole: implications for drug efficacy in oropharyngeal and esophageal candidiasis.
Topics: Administration, Oral; Adult; Candida albicans; Candidiasis; Chromatography, High Pressure Liquid; Cross-Over Studies; Esophageal Diseases; Female; Fluconazole; Humans; Ketoconazole; Male; Microbial Sensitivity Tests; Oropharynx; Pharyngeal Diseases; Saliva | 1995 |
Emergence of azole drug resistance in Candida species from HIV-infected patients receiving prolonged fluconazole therapy for oral candidosis.
Topics: Antifungal Agents; Azoles; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Fluconazole; HIV Infections; Humans; Ketoconazole; Microbial Sensitivity Tests; Mouth | 1995 |
Fluconazole versus ketoconazole in the treatment of dermatophytoses and cutaneous candidiasis.
Topics: Adult; Candida; Candidiasis, Cutaneous; Double-Blind Method; Female; Fluconazole; Follow-Up Studies; Humans; Ketoconazole; Male; Placebos; Recurrence; Remission Induction; Superinfection; Tinea; Tinea Pedis; Trichophyton | 1994 |
Fluconazole versus ketoconazole in the treatment of oropharyngeal candidiasis in HIV-infected children. Multicentre Study Group.
Topics: Adolescent; Age Factors; AIDS-Related Opportunistic Infections; Candida; Candidiasis, Oral; Child; Child, Preschool; Female; Fluconazole; Humans; Immunocompromised Host; Infant; Infant, Newborn; Ketoconazole; Male; Pharyngeal Diseases; Prospective Studies; Time Factors | 1994 |
Prevention of symptomatic recurrences of esophageal candidiasis in AIDS patients after the first episode: a prospective open study.
Topics: Adult; AIDS-Related Opportunistic Infections; Candidiasis; Esophagitis; Female; Fluconazole; Follow-Up Studies; Humans; Ketoconazole; Male; Prospective Studies; Recurrence; Time Factors | 1994 |
Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers.
Topics: Adult; Antifungal Agents; Cimetidine; Fluconazole; Histamine H2 Antagonists; Humans; Ketoconazole; Male; Microsomes, Liver; Reference Values; Sulfamethoxazole | 1996 |
The effect of fluconazole and ketoconazole on the metabolism of sulphamethoxazole.
Topics: Adult; Anti-Infective Agents; Antifungal Agents; Fluconazole; Humans; Hydroxylation; Ketoconazole; Male; Middle Aged; Sulfamethoxazole | 1996 |
Analysis of the risk factors associated with the emergence of azole resistant oral candidosis in the course of HIV infection.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis, Oral; Drug Resistance, Microbial; Female; Fluconazole; Follow-Up Studies; Humans; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Reference Values; Risk Factors | 1996 |
Clinical response to ketoconazole of HIV-related oral candidosis is predicted by Odds' relative growth method of susceptibility testing.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candidiasis, Oral; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Predictive Value of Tests | 1997 |
Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole.
Topics: Administration, Oral; Adult; Antifungal Agents; Cross-Over Studies; Double-Blind Method; Female; Fluconazole; Half-Life; Humans; Hypnotics and Sedatives; Itraconazole; Ketoconazole; Male; Pyridines; Reference Values; Zolpidem | 1998 |
[Fluconazole versus ketoconazole in systemic fungal infection: a double-blind randomized study].
Topics: Adolescent; Adult; Aged; Antifungal Agents; Candidiasis, Oral; Double-Blind Method; Female; Fluconazole; Humans; Ketoconazole; Lung Diseases, Fungal; Male; Middle Aged; Mycoses; Vaginitis | 1997 |
Comparative efficacy of ketoconazole and fluconazole in the treatment of pityriasis versicolor: a one year follow-up study.
Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Child; Drug Administration Schedule; Female; Fluconazole; Follow-Up Studies; Humans; Ketoconazole; Male; Middle Aged; Tinea Versicolor; Treatment Outcome | 2001 |
Fluconazole versus ketoconazole in the treatment of tinea versicolor.
Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Double-Blind Method; Drug Administration Schedule; Exanthema; Fatigue; Female; Fluconazole; Follow-Up Studies; Headache; Humans; Ketoconazole; Malassezia; Male; Middle Aged; Safety; Tinea Versicolor; Treatment Outcome | 2002 |
Combination therapy of once-weekly fluconazole (100, 150, or 300 mg) with topical application of ketoconazole cream in the treatment of onychomycosis.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Antifungal Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluconazole; Humans; Ketoconazole; Male; Middle Aged; Onychomycosis | 2004 |
Effect of azole antifungals ketoconazole and fluconazole on the pharmacokinetics of dexloxiglumide.
Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Area Under Curve; Cross-Over Studies; Drug Combinations; Female; Fluconazole; Humans; Ketoconazole; Male; Pentanoic Acids; Receptors, Cholecystokinin; Time Factors | 2005 |
Effects of three cytochrome P450 inhibitors, ketoconazole, fluconazole, and paroxetine, on the pharmacokinetics of lasofoxifene.
Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Antifungal Agents; Area Under Curve; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Ketoconazole; Middle Aged; Paroxetine; Postmenopause; Pyrrolidines; Tetrahydronaphthalenes | 2007 |
Antifungal treatment in sarcoidosis--a pilot intervention trial.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antifungal Agents; Drug Therapy, Combination; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Middle Aged; Pilot Projects; Sarcoidosis; Treatment Outcome | 2007 |
Value of colposcopy in the diagnosis of candidiasis in patients with vulvodynia.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Candidiasis; Colposcopy; Female; Fluconazole; Humans; Ketoconazole; Middle Aged; Pain; Vulvar Diseases | 2007 |
Comparison between fluconazole and ketoconazole effectivity in the treatment of pityriasis versicolor.
Topics: Adult; Antifungal Agents; Female; Fluconazole; Humans; Iran; Ketoconazole; Male; Surveys and Questionnaires; Tinea Versicolor | 2007 |
A study to evaluate the efficacy and safety of oral fluconazole in the treatment of tinea versicolor.
Topics: Adolescent; Adult; Antifungal Agents; Bangladesh; Female; Fluconazole; Humans; Incidence; Itraconazole; Ketoconazole; Male; Middle Aged; Prevalence; Risk Factors; Tinea Versicolor; Treatment Outcome; Young Adult | 2009 |
Quantitative prediction and clinical observation of a CYP3A inhibitor-based drug-drug interactions with MLN3897, a potent C-C chemokine receptor-1 antagonist.
Topics: Adult; Cross-Over Studies; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Inhibitors; Female; Fluconazole; Hepatocytes; Humans; Ketoconazole; Male; Microsomes, Liver; Models, Biological; Receptors, CCR1 | 2010 |
A noninferiority clinical trial comparing fluconazole and ketoconazole in combination with cephalexin for the treatment of dogs with Malassezia dermatitis.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Cephalexin; Dermatomycoses; Dog Diseases; Dogs; Drug Therapy, Combination; Fluconazole; Ketoconazole; Malassezia | 2010 |
Pharmacokinetic drug interactions involving vortioxetine (Lu AA21004), a multimodal antidepressant.
Topics: Adolescent; Adult; Antidepressive Agents; Antifungal Agents; Bupropion; Cohort Studies; Contraceptives, Oral, Hormonal; Cross-Over Studies; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Female; Fluconazole; Humans; Ketoconazole; Male; Middle Aged; Omeprazole; Piperazines; Rifampin; Single-Blind Method; Sulfides; Vortioxetine; Young Adult | 2013 |
Comparative clinical trial: fluconazole alone or associated with topical ketoconazole in the treatment of pityriasis versicolor.
Topics: Adolescent; Adult; Aged; Antifungal Agents; Drug Therapy, Combination; Female; Fluconazole; Hair Preparations; Humans; Ketoconazole; Male; Middle Aged; Tinea Versicolor; Young Adult | 2016 |
Effects of CYP3A inhibitors on the pharmacokinetics of quizartinib, a potent and selective FLT3 inhibitor, and its active metabolite.
Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Area Under Curve; Benzothiazoles; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluconazole; fms-Like Tyrosine Kinase 3; Healthy Volunteers; Humans; Invasive Fungal Infections; Ketoconazole; Leukemia, Myeloid, Acute; Male; Middle Aged; Phenylurea Compounds; Young Adult | 2019 |
434 other study(ies) available for fluconazole and ketoconazole
Article | Year |
---|---|
Synthesis and antifungal activity of new azole derivatives containing an N-acylmorpholine ring.
Topics: Animals; Antifungal Agents; Azoles; Candidiasis; Female; Male; Mice; Microbial Sensitivity Tests; Rats; Rats, Wistar; Stereoisomerism; Structure-Activity Relationship | 1995 |
Novel antifungals based on 4-substituted imidazole: a combinatorial chemistry approach to lead discovery and optimization.
Topics: Antifungal Agents; Candida; Combinatorial Chemistry Techniques; Drug Design; Ergosterol; Fungi; Imidazoles; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2000 |
3-Phenyl-5-acyloxymethyl-2H,5H-furan-2-ones: synthesis and biological activity of a novel group of potential antifungal drugs.
Topics: 4-Butyrolactone; Amphotericin B; Antifungal Agents; Fungi; Furans; Humans; Microbial Sensitivity Tests; Stereoisomerism; Structure-Activity Relationship | 2001 |
Interaction of common azole antifungals with P glycoprotein.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azoles; Cell Line; Hydrolysis; Mice | 2002 |
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine | 2002 |
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine | 2002 |
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship | 2003 |
Imidazole analogues of fluoxetine, a novel class of anti-Candida agents.
Topics: Antifungal Agents; Candida albicans; Cell Line, Tumor; Cell Survival; Fluoxetine; Humans; Imidazoles; Microbial Sensitivity Tests; Structure-Activity Relationship | 2004 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking.
Topics: Antifungal Agents; Azoles; Binding Sites; Databases, Factual; Fungi; Hydrogen Bonding; In Vitro Techniques; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship | 2006 |
Reduced susceptibility to polyenes associated with a missense mutation in the ERG6 gene in a clinical isolate of Candida glabrata with pseudohyphal growth.
Topics: Antifungal Agents; Candida glabrata; Candidiasis; DNA Primers; Genes, Fungal; Genetic Complementation Test; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation, Missense; Phenotype; Polyenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Fungal; RNA, Messenger; Sterols | 2007 |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors.
Topics: Amides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Indoles; Models, Molecular; Oxidoreductases; Quantitative Structure-Activity Relationship; Sterol 14-Demethylase | 2007 |
A Candida albicans petite mutant strain with uncoupled oxidative phosphorylation overexpresses MDR1 and has diminished susceptibility to fluconazole and voriconazole.
Topics: Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Candida albicans; Drug Resistance, Fungal; Fluconazole; Microbial Sensitivity Tests; Mutation; Oxidative Phosphorylation; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Triazoles; Voriconazole | 2007 |
Synthesis of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase (CYP51).
Topics: Antifungal Agents; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Triazoles | 2007 |
Discovery of novel indazole-linked triazoles as antifungal agents.
Topics: Administration, Oral; Animals; Antifungal Agents; Aspergillus; Candida; Disease Models, Animal; Indazoles; Mice; Microbial Sensitivity Tests; Rats; Stereoisomerism; Triazoles | 2007 |
In vitro susceptibility of Sporothrix schenckii to six antifungal agents determined using three different methods.
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Flucytosine; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Quality Control; Sporothrix; Sporotrichosis; Triazoles; Voriconazole | 2007 |
In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Caspofungin; Echinocandins; Fluconazole; Flucytosine; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Mucormycosis; Peptides, Cyclic; Pyrimidines; Triazoles; Voriconazole | 2007 |
Role for cell density in antifungal drug resistance in Candida albicans biofilms.
Topics: Amphotericin B; Antifungal Agents; Biofilms; Candida albicans; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Microbial Sensitivity Tests | 2007 |
Cross-resistance to medical and agricultural azole drugs in yeasts from the oropharynx of human immunodeficiency virus patients and from environmental Bavarian vine grapes.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Azoles; Candida albicans; Candidiasis, Oral; Drug Resistance, Fungal; Environmental Microbiology; Fungicides, Industrial; Germany; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Oropharynx; Vitis | 2007 |
The Ssk1p response regulator and Chk1p histidine kinase mutants of Candida albicans are hypersensitive to fluconazole and voriconazole.
Topics: Antifungal Agents; Candida albicans; Culture Media; Drug Resistance, Fungal; Fluconazole; Histidine Kinase; Microbial Sensitivity Tests; Mutation; Phenotype; Phosphorylation; Protein Kinases; Pyrimidines; Signal Transduction; Triazoles; Voriconazole | 2007 |
Synthesis and antifungal activities of novel 2-aminotetralin derivatives.
Topics: Administration, Intravaginal; Animals; Antifungal Agents; Binding Sites; Candida albicans; Candidiasis; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Female; Fluconazole; Microbial Sensitivity Tests; Models, Molecular; Oxidoreductases; Protein Binding; Rats; Sterol 14-Demethylase; Structure-Activity Relationship; Tetrahydronaphthalenes; Vaginal Diseases | 2007 |
Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51).
Topics: Anticholesteremic Agents; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Humans; Oxidoreductases; Pyridines; Sterol 14-Demethylase; Structure-Activity Relationship | 2008 |
Antifungal and cytotoxic activities of some N-substituted aniline derivatives bearing a hetaryl fragment.
Topics: Aniline Compounds; Antifungal Agents; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Imines; Microbial Sensitivity Tests; Molecular Structure; National Cancer Institute (U.S.); United States | 2008 |
In vitro antifungal susceptibilities of five species of sporothrix.
Topics: Animals; Antifungal Agents; Drug Resistance, Fungal; Humans; Microbial Sensitivity Tests; Species Specificity; Sporothrix; Sporotrichosis | 2008 |
Reliability of the WIDERYST susceptibility testing system for detection of in vitro antifungal resistance in yeasts.
Topics: Amphotericin B; Antifungal Agents; Azoles; Candida; Culture Media; Drug Resistance, Fungal; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Reproducibility of Results; Yeasts | 2008 |
Potent in vitro antifungal activities of naturally occurring acetylenic acids.
Topics: Alkynes; Animals; Antifungal Agents; Candida albicans; Cell Line; Fatty Acids, Unsaturated; Fungi; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Plants, Medicinal; Rubiaceae; Trichophyton | 2008 |
Synthesis and SAR studies of biaryloxy-substituted triazoles as antifungal agents.
Topics: Antifungal Agents; Candida albicans; Fluconazole; Humans; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Triazoles; Voriconazole; Yeasts | 2008 |
1-[(3-Aryloxy-3-aryl)propyl]-1H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies.
Topics: Antifungal Agents; Arthrodermataceae; Candida albicans; Cell Line, Tumor; Cell Survival; Computer Simulation; Humans; Imidazoles; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2008 |
Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus.
Topics: Antifungal Agents; Azoles; Base Sequence; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Fungal; Drug Resistance, Fungal; Genes, Fungal; Humans; Molecular Sequence Data; Recombinant Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Species Specificity; Sterol 14-Demethylase | 2008 |
A nonsense mutation in the ERG6 gene leads to reduced susceptibility to polyenes in a clinical isolate of Candida glabrata.
Topics: Antifungal Agents; Azoles; Base Sequence; Candida glabrata; Candidiasis; Codon, Nonsense; DNA, Fungal; Drug Resistance, Fungal; Ergosterol; Genes, Fungal; Guanine; Humans; Molecular Sequence Data; Polyenes | 2008 |
Abc1p is a multidrug efflux transporter that tips the balance in favor of innate azole resistance in Candida krusei.
Topics: Amino Acid Sequence; Animals; Antifungal Agents; ATP-Binding Cassette Transporters; Azoles; Blotting, Northern; Blotting, Southern; Candida; Candidiasis; Cell Membrane; Chromosomes, Fungal; Drug Resistance, Fungal; Endoplasmic Reticulum; Humans; Phenotype; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Saccharomyces cerevisiae | 2009 |
Identification, characterization, and azole-binding properties of Mycobacterium smegmatis CYP164A2, a homolog of ML2088, the sole cytochrome P450 gene of Mycobacterium leprae.
Topics: Amino Acid Motifs; Amino Acid Sequence; Azoles; Base Sequence; Cloning, Molecular; Conserved Sequence; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Genes, Bacterial; Hydrogen-Ion Concentration; Molecular Sequence Data; Molecular Structure; Molecular Weight; Mycobacterium leprae; Mycobacterium smegmatis; Osmolar Concentration; Recombinant Proteins; Sequence Homology, Amino Acid; Sodium Chloride | 2009 |
Design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase.
Topics: Antifungal Agents; Aspergillus fumigatus; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Enzyme Inhibitors; Protein Binding; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles | 2009 |
Synthesis and antifungal activity of 1,2,3-triazole containing fluconazole analogues.
Topics: Animals; Antifungal Agents; Bile Acids and Salts; Candida albicans; Candidiasis; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Fluconazole; Humans; Inhibitory Concentration 50; Mice; Models, Chemical; Triazoles | 2009 |
Comparative chemometric modeling of cytochrome 3A4 inhibitory activity of structurally diverse compounds using stepwise MLR, FA-MLR, PLS, GFA, G/PLS and ANN techniques.
Topics: Algorithms; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Enzyme Inhibitors; Factor Analysis, Statistical; Least-Squares Analysis; Linear Models; Models, Molecular; Neural Networks, Computer; Quantitative Structure-Activity Relationship; Reproducibility of Results | 2009 |
In vitro activities of retigeric acid B alone and in combination with azole antifungal agents against Candida albicans.
Topics: Antifungal Agents; Azoles; Candida albicans; Fluconazole; Itraconazole; Ketoconazole; Lichens; Microbial Sensitivity Tests; Triterpenes | 2009 |
Fenticonazole activity measured by the methods of the European Committee on Antimicrobial Susceptibility Testing and CLSI against 260 Candida vulvovaginitis isolates from two European regions and annotations on the prevalent genotypes.
Topics: Adult; Antifungal Agents; Candida albicans; Candida glabrata; Candidiasis, Vulvovaginal; Cluster Analysis; DNA Fingerprinting; Drug Resistance, Fungal; Europe; Female; Fluconazole; Genotype; Humans; Imidazoles; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious; Prevalence | 2009 |
Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance.
Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Azoles; Candida albicans; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Membrane Transport Proteins; Microbial Sensitivity Tests; Rhodamines | 2009 |
Design, synthesis, and biological evaluation of novel 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted benzylamino-2-propanols.
Topics: Antifungal Agents; Catalytic Domain; Chemistry, Pharmaceutical; Computer Simulation; Crystallography, X-Ray; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Design; Fluconazole; Fungal Proteins; Microbial Sensitivity Tests; Models, Chemical; Propanols; Protein Binding; Triazoles | 2009 |
Hypersusceptibility to azole antifungals in a clinical isolate of Candida glabrata with reduced aerobic growth.
Topics: Adult; Aerobiosis; Antifungal Agents; Azoles; Candida glabrata; Chromatography, High Pressure Liquid; Ergosterol; Female; Flow Cytometry; Genes, Fungal; Humans; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Molecular Sequence Data; Polyenes | 2009 |
Bulky 1,4-benzoxazine derivatives with antifungal activity.
Topics: Animals; Antifungal Agents; Benzoxazines; Candida; Cryptococcus neoformans; Female; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure | 2009 |
In vitro activity of thimerosal against ocular pathogenic fungi.
Topics: Alternaria; Amphotericin B; Antifungal Agents; Aspergillus; Eye Infections, Fungal; Fungi; Fusarium; Humans; Microbial Sensitivity Tests; Natamycin; Thimerosal | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives.
Topics: Animals; Anti-Infective Agents; Cell Line; Ecology; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Magnetic Resonance Spectroscopy; Mice; Microbial Sensitivity Tests; Oxazines; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2010 |
A clinical isolate of Candida albicans with mutations in ERG11 (encoding sterol 14alpha-demethylase) and ERG5 (encoding C22 desaturase) is cross resistant to azoles and amphotericin B.
Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Drug Resistance, Fungal; Fungal Proteins; Microbial Sensitivity Tests; Mutation; Polymerase Chain Reaction | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities.
Topics: Animals; Anti-Infective Agents; Antiviral Agents; Bacteria; Cell Line; Chlorocebus aethiops; Drug Evaluation, Preclinical; Fungi; Herpesvirus 1, Human; Mannich Bases; Microbial Sensitivity Tests; Parainfluenza Virus 3, Human; Pyrones; Spectrum Analysis; Vero Cells | 2010 |
Synthesis and antifungal evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase.
Topics: 14-alpha Demethylase Inhibitors; Antifungal Agents; Fungi; Humans; Models, Molecular; Mycoses; Sterol 14-Demethylase; Triazoles | 2010 |
Identification and characterization of four azole-resistant erg3 mutants of Candida albicans.
Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Ergosterol; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mutation; Oxidoreductases; Pyrimidines; Triazoles; Voriconazole | 2010 |
Analysis of physico-chemical properties of substrates of ABC and MFS multidrug transporters of pathogenic Candida albicans.
Topics: Candida albicans; Membrane Transport Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives.
Topics: Antifungal Agents; Candida albicans; Catalytic Domain; Cryptococcus neoformans; Cytochrome P-450 Enzyme Inhibitors; Drug Design; Fluconazole; Fungal Proteins; Microbial Sensitivity Tests; Molecular Docking Simulation; Piperazines; Sterol 14-Demethylase; Structure-Activity Relationship; Triazoles; Voriconazole | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Antifungal activities of novel non-azole molecules against S. cerevisiae and C. albicans.
Topics: Antifungal Agents; Candida albicans; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Liver; Models, Molecular; Nitriles; Protein Conformation; Saccharomyces cerevisiae; Sterol 14-Demethylase; User-Computer Interface | 2012 |
Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity.
Topics: Anti-Infective Agents; Bacteria; Chemistry Techniques, Synthetic; Fungi; Indoles; Microbial Sensitivity Tests; Oxindoles | 2012 |
New triazole derivatives as antifungal agents: synthesis via click reaction, in vitro evaluation and molecular docking studies.
Topics: Antifungal Agents; Catalysis; Catalytic Domain; Click Chemistry; Computer Simulation; Copper; Fungi; Humans; Microbial Sensitivity Tests; Triazoles | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Synthesis, in vitro antifungal activity and in silico study of 3-(1,2,4-triazol-1-yl)flavanones.
Topics: Antifungal Agents; Catalytic Domain; Chemistry Techniques, Synthetic; Flavanones; Fungi; Microbial Sensitivity Tests; Molecular Docking Simulation; Sterol 14-Demethylase | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Synthesis and evaluation of novel azoles as potent antifungal agents.
Topics: Antifungal Agents; Azoles; Dose-Response Relationship, Drug; Fungi; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2014 |
Synthesis, antifungal activities and molecular docking studies of novel 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates.
Topics: Aspergillus fumigatus; Candida; Carbamates; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Docking Simulation | 2014 |
Polyhydroxy cyclohexanols from a Dendrodochium sp. fungus associated with the sea cucumber Holothuria nobilis Selenka.
Topics: Animals; Antifungal Agents; Cryptococcus neoformans; Cyclohexanols; Holothuria; Humans; Microbial Sensitivity Tests; Molecular Structure; Oceans and Seas; Trichophyton | 2014 |
Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies.
Topics: Anti-Infective Agents; Benzodioxoles; Binding Sites; DNA Topoisomerase IV; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Microwaves; Molecular Docking Simulation; Protein Binding; Pyrazoles; Structure-Activity Relationship; Thermodynamics; Thiazoles; Thiophenes | 2015 |
Phenoxymethyl 1,3-oxazoles and 1,2,4-oxadiazoles as potent and selective agonists of free fatty acid receptor 1 (GPR40).
Topics: Animals; Binding Sites; Caco-2 Cells; Cytochrome P-450 Enzyme System; Half-Life; Humans; Methylamines; Mice; Molecular Docking Simulation; Oxadiazoles; Oxazoles; Propionates; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2015 |
Synthesis and antifungal evaluation of head-to-head and head-to-tail bisamidine compounds.
Topics: Antifungal Agents; Candida; Cryptococcus neoformans; DNA-Binding Proteins; Furans; Humans | 2015 |
Anti-Candida activity and cytotoxicity of a large library of new N-substituted-1,3-thiazolidin-4-one derivatives.
Topics: 14-alpha Demethylase Inhibitors; Anti-Bacterial Agents; Antifungal Agents; Candida; Chemistry Techniques, Synthetic; Drug Design; Drug Evaluation, Preclinical; Fungal Proteins; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Small Molecule Libraries; Sterol 14-Demethylase; Structure-Activity Relationship; Thiazolidines | 2016 |
Discovery of Potent Benzofuran-Derived Diapophytoene Desaturase (CrtN) Inhibitors with Enhanced Oral Bioavailability for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infections.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzofurans; Biological Availability; Drug Discovery; Enzyme Inhibitors; Female; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Oxidoreductases; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Tissue Distribution | 2016 |
Novel 1,3-thiazolidin-4-one derivatives as promising anti-Candida agents endowed with anti-oxidant and chelating properties.
Topics: Antifungal Agents; Antioxidants; Candida; Chelating Agents; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Thiazolidines; Toxicity Tests | 2016 |
Discovery of Benzocycloalkane Derivatives Efficiently Blocking Bacterial Virulence for the Treatment of Methicillin-Resistant S. aureus (MRSA) Infections by Targeting Diapophytoene Desaturase (CrtN).
Topics: Alkanes; Anti-Bacterial Agents; Antifungal Agents; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Fungi; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Structure; Oxidoreductases; Staphylococcal Infections; Structure-Activity Relationship | 2016 |
2-(3-Methoxyphenyl)quinazoline Derivatives: A New Class of Direct Constitutive Androstane Receptor (CAR) Agonists.
Topics: Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hep G2 Cells; Hepatocytes; Humans; Models, Molecular; Molecular Structure; Quinazolines; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship | 2016 |
Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold.
Topics: Amides; Animals; Drug Delivery Systems; Humans; Hypoglycemic Agents; Mice; Microsomes, Liver; Molecular Docking Simulation; Protein Binding; Receptors, G-Protein-Coupled; Thiadiazoles | 2016 |
Discovery of biphenyl imidazole derivatives as potent antifungal agents: Design, synthesis, and structure-activity relationship studies.
Topics: Antifungal Agents; Biphenyl Compounds; Candida albicans; Cryptococcus neoformans; Dose-Response Relationship, Drug; Drug Discovery; Imidazoles; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2017 |
Design, synthesis, and in vitro evaluation of novel antifungal triazoles.
Topics: Antifungal Agents; Crystallography, X-Ray; Drug Design; Fungi; Microbial Sensitivity Tests; Molecular Conformation; Nitriles; Pyridines; Structure-Activity Relationship; Thiazoles; Triazoles | 2017 |
Design, synthesis and evaluation of aromatic heterocyclic derivatives as potent antifungal agents.
Topics: Antifungal Agents; Aspergillus fumigatus; Candida albicans; Cryptococcus neoformans; Dose-Response Relationship, Drug; Drug Design; Heterocyclic Compounds; Hydrocarbons, Aromatic; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship | 2017 |
Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Drug Resistance, Bacterial; Ether-A-Go-Go Potassium Channels; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Structure-Activity Relationship; Vancomycin; Vancomycin Resistance; Xanthophylls | 2017 |
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.
Topics: Animals; Drug Design; Enzyme Inhibitors; ERG1 Potassium Channel; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Oxidoreductases; Rats; Safety; Solubility; Structure-Activity Relationship; Water | 2018 |
Antifungal activity, mode of action variability, and subcellular distribution of coumarin-based antifungal azoles.
Topics: Antifungal Agents; Azoles; Candida; Cell Survival; Coumarins; Dose-Response Relationship, Drug; HEK293 Cells; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Optical Imaging; Structure-Activity Relationship | 2019 |
Fluconazole and ketoconazole in the treatment of oral and esophageal candidiasis in AIDS patients.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Candidiasis; Candidiasis, Oral; Esophageal Diseases; Female; Fluconazole; Humans; Ketoconazole; Male; Middle Aged | 1992 |
Drugs for treatment of fungal infections.
Topics: Amphotericin B; Antifungal Agents; Drug Interactions; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Mycoses; Opportunistic Infections | 1992 |
The evaluation of therapeutic responses in experimental keratomycosis.
Topics: Administration, Oral; Animals; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Colony Count, Microbial; Disease Models, Animal; Eye Infections, Fungal; Fluconazole; Itraconazole; Keratitis; Ketoconazole; Observer Variation; Rabbits | 1992 |
Interaction of azoles with rifampin, phenytoin, and carbamazepine: in vitro and clinical observations.
Topics: Adult; Aged; Antifungal Agents; Azoles; Carbamazepine; Coccidioides; Cryptococcus neoformans; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Malassezia; Male; Middle Aged; Mycoses; Phenytoin; Rifampin | 1992 |
[New treatments of onychomycoses].
Topics: Administration, Topical; Antifungal Agents; Candidiasis; Ciclopirox; Fluconazole; Foot Dermatoses; Hand Dermatoses; Humans; Itraconazole; Ketoconazole; Morpholines; Onychomycosis; Pyridones | 1992 |
In vitro antifungal spectrum of itraconazole and treatment of systemic mycoses with old and new antimycotic agents.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Drug Therapy, Combination; Fluconazole; Flucytosine; Guinea Pigs; Immunocompromised Host; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Sporotrichosis | 1992 |
[Sphenoid sinus aspergillosis presenting abducens nerve palsy and visual field impairment; a case report].
Topics: Abducens Nerve; Aged; Antifungal Agents; Aspergillosis; Cranial Nerve Diseases; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Paralysis; Paranasal Sinus Diseases; Sphenoid Sinus; Visual Fields | 1992 |
Effects of culture media on the in vitro susceptibility of selected opportunistic fungi to fluconazole and itraconazole.
Topics: Alternaria; Antifungal Agents; Aspergillus; Candida; Culture Media; Fluconazole; Fungi; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Pseudallescheria | 1992 |
New antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Dermatomycoses; Fluconazole; Humans; Itraconazole; Ketoconazole; Naphthalenes; Terbinafine | 1992 |
Comparative study of six antifungal treatments in an experimental model of murine cryptococcosis.
Topics: Amphotericin B; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Mice; Mice, Inbred BALB C; Triazoles | 1992 |
In vitro susceptibility of 245 yeast isolates to amphotericin B, 5-fluorocytosine, ketoconazole, fluconazole and itraconazole.
Topics: Amphotericin B; Antifungal Agents; Candida; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Species Specificity | 1992 |
The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells.
Topics: Antifungal Agents; Cells, Cultured; Cyclosporine; Cytokines; Fluconazole; Gene Expression; Humans; Itraconazole; Ketoconazole; Lymphocytes; Miconazole; Tacrolimus | 1992 |
Fluconazole: a potent inhibitor of cytochrome P-450-dependent drug-metabolism in mice and humans in vivo. Comparative study with ketoconazole.
Topics: Adult; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Fluconazole; Humans; Hydrocortisone; Ketoconazole; Male; Mice; Microsomes, Liver; Middle Aged | 1992 |
Reduced azole susceptibility of oral isolates of Candida albicans from HIV-positive patients and a derivative exhibiting colony morphology variation.
Topics: Candida albicans; Candidiasis, Oral; DNA, Fungal; Fluconazole; HIV Infections; Humans; Ketoconazole; Lipids; Microbial Sensitivity Tests; Sterols | 1992 |
Cryptococcal peritonitis in a CAPD patient.
Topics: Cryptococcosis; Female; Fluconazole; Humans; Ketoconazole; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis | 1992 |
[Q-DIPS: current approach to prediction of drug interactions].
Topics: Biotransformation; Computer Simulation; Drug Interactions; Fluconazole; Humans; Ketoconazole; Liver; Pharmacokinetics; Probability; Software | 1992 |
Cryptococcal meningitis in AIDS occurring despite systemic antifungal therapy.
Topics: Acquired Immunodeficiency Syndrome; Fluconazole; Humans; Ketoconazole; Meningitis, Cryptococcal | 1992 |
Comparison of SCH 39304, fluconazole, and ketoconazole for treatment of systemic infections in mice.
Topics: Administration, Oral; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Drug Evaluation, Preclinical; Fluconazole; Injections, Intravenous; Ketoconazole; Kidney; Male; Mice; Triazoles | 1992 |
Comparison of the immunosuppressive activities of the antimycotic agents itraconazole, fluconazole, ketoconazole and miconazole on human T-cells.
Topics: Antifungal Agents; Cytokines; Fluconazole; Humans; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Itraconazole; Ketoconazole; Lymphocyte Activation; Miconazole; T-Lymphocytes | 1991 |
Fluconazole, itraconazole and ketoconazole in-vitro activity. A comparative study.
Topics: Antifungal Agents; Candida; Cryptococcus; Fluconazole; Fungi; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 1991 |
Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes.
Topics: Adult; Antifungal Agents; Cyclosporine; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Microsomes, Liver; Naphthalenes; Terbinafine | 1991 |
The anti-fungal agent itraconazole exerts immunosuppressive effects on alloreactivity but not on natural immunity in vitro.
Topics: Antifungal Agents; Fluconazole; Humans; Immunity; Immunity, Innate; Immunosuppressive Agents; In Vitro Techniques; Itraconazole; Ketoconazole; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Culture Test, Mixed | 1991 |
Candida zeylanoides: another opportunistic yeast.
Topics: Amphotericin B; Candida; Catheterization, Central Venous; DNA, Fungal; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Female; Fluconazole; Flucytosine; Humans; Ketoconazole; Microbial Sensitivity Tests; Middle Aged; Parenteral Nutrition, Total; Polymorphism, Restriction Fragment Length | 1991 |
Synergistic action of nikkomycin X/Z with azole antifungals on Candida albicans.
Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Azoles; Biological Transport; Candida albicans; Drug Synergism; Fluconazole; Glucose; Imidazoles; Ketoconazole; Kinetics; Polysaccharides | 1991 |
Fluconazole resistance in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Adult; Candidiasis, Oral; Drug Resistance, Microbial; Female; Fluconazole; Humans; Ketoconazole; Male; Microbial Sensitivity Tests | 1991 |
[In vivo and in vitro antifungal activity of fluconazole].
Topics: Animals; Aspergillus; Candida albicans; Candidiasis; Cryptococcus; Drug Resistance, Microbial; Fluconazole; Ketoconazole; Male; Mice; Mice, Inbred ICR; Miconazole | 1991 |
Black grain eumycetoma (Madurella mycetomatis) in the abdominal cavity of a dog.
Topics: Abdomen; Animals; Culture Media; Dog Diseases; Dogs; Escherichia coli; Female; Fluconazole; Granuloma; Ketoconazole; Mitosporic Fungi; Mycetoma | 1991 |
Failure of ketoconazole maintenance therapy for disseminated coccidioidomycosis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Coccidioidomycosis; Fluconazole; Humans; Ketoconazole; Male | 1991 |
Rhinofacial zygomycosis caused by Conidiobolus coronatus. A case report.
Topics: Aged; Agricultural Workers' Diseases; Brazil; Edema; Face; Female; Fluconazole; Fungi; Humans; Ketoconazole; Mycoses; Nose; Recurrence | 1991 |
Bioavailability of fluconazole and ketoconazole in human stratum corneum and oral mucosa.
Topics: Adult; Biological Availability; Candida albicans; Fluconazole; Humans; Ketoconazole; Mouth Mucosa; Skin; Trichophyton | 1991 |
Opportunistic infections of the esophagus not responding to oral systemic antifungals in patients with AIDS: their frequency and treatment.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Administration, Oral; Adult; Amphotericin B; Antifungal Agents; Drug Resistance, Microbial; Esophagitis; Female; Fluconazole; Ganciclovir; Humans; Infusions, Intravenous; Ketoconazole; Male; Opportunistic Infections; Prospective Studies; Treatment Outcome | 1991 |
Treatment of cryptococcal meningitis with five anti-fungal drugs: the role of amphotericin B.
Topics: Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Drug Therapy, Combination; Female; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Male; Meningitis; Miconazole; Middle Aged | 1990 |
Treatment of refractory oral candidiasis with fluconazole. A case report.
Topics: Acquired Immunodeficiency Syndrome; Adult; Amphotericin B; Candida albicans; Candidiasis, Oral; Clotrimazole; Deglutition Disorders; Drug Resistance, Microbial; Esophageal Diseases; Fluconazole; Humans; Ketoconazole; Male | 1991 |
In vitro susceptibility of 119 yeast isolates to fluconazole, 5-fluorocytosine, amphotericin B and ketoconazole.
Topics: Amphotericin B; Candida; Cryptococcus neoformans; Culture Media; Fluconazole; Flucytosine; Ketoconazole; Microbial Sensitivity Tests; Saccharomyces cerevisiae; Species Specificity; Yeasts | 1991 |
Fluconazole resistant candida in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Candidiasis, Oral; Drug Resistance, Microbial; Fluconazole; Humans; Ketoconazole; Male | 1991 |
Candida albicans resistance in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Candidiasis, Oral; Drug Resistance, Microbial; Esophageal Diseases; Fluconazole; Humans; Ketoconazole; Male | 1991 |
The effectiveness of a preventive regimen on the periodontal health of patients undergoing chemotherapy for leukemia and lymphoma.
Topics: Acyclovir; Amphotericin B; Ceftazidime; Chlorhexidine; Dental Plaque Index; Fluconazole; Humans; Immunosuppression Therapy; Ketoconazole; Leukemia; Lymphoma; Miconazole; Norfloxacin; Periodontal Diseases; Periodontal Index; Tooth Loss; Vancomycin | 1991 |
SCH 39304 in the treatment of acute or established murine pulmonary blastomycosis.
Topics: Animals; Antifungal Agents; Blastomycosis; Fluconazole; Ketoconazole; Lung Diseases; Mice; Mice, Inbred BALB C; Triazoles | 1991 |
Susceptibility of several species of Candida and Torulopsis to fluconazole and ketoconazole.
Topics: Candida; Fluconazole; Ketoconazole; Microbial Sensitivity Tests | 1990 |
Diabetic ketoacidosis precipitated by primary genital herpes.
Topics: Acyclovir; Adolescent; Adult; Diabetic Ketoacidosis; Female; Fluconazole; Herpes Simplex; Humans; Ketoconazole | 1990 |
Evaluation of Bay R 3783 in rodent models of superficial and systemic candidiasis, meningeal cryptococcosis, and pulmonary aspergillosis.
Topics: Administration, Oral; Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Disease Models, Animal; Drug Administration Schedule; Evaluation Studies as Topic; Female; Fluconazole; Itraconazole; Ketoconazole; Lung Diseases, Fungal; Male; Meningitis; Mice; Pharmaceutical Vehicles; Rats; Rats, Inbred Strains; Triazoles | 1990 |
Treatment of murine coccidioidal meningitis with SCH39304.
Topics: Animals; Antifungal Agents; Coccidioidomycosis; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Fluconazole; Itraconazole; Ketoconazole; Meningitis; Mice; Mice, Inbred BALB C; Triazoles | 1990 |
Effect of amphotericin B, fluconazole and itraconazole on intracellular Candida albicans and germ tube development in macrophages.
Topics: Amphotericin B; Animals; Antifungal Agents; Candida albicans; Cells, Cultured; Colony Count, Microbial; Fluconazole; Itraconazole; Ketoconazole; Macrophages; Mice; Phagocytosis | 1990 |
[Comparative sensitivity of yeasts to ketoconazole, itraconazole and fluconazole using a liquid medium standardized micromethod].
Topics: Antifungal Agents; Drug Resistance, Microbial; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Yeasts | 1990 |
The pharmacokinetics of BAY R3783 and its efficacy in the treatment of experimental cryptococcal meningitis.
Topics: Animals; Cryptococcosis; Cryptococcus neoformans; Fluconazole; Itraconazole; Ketoconazole; Meningitis; Rabbits; Triazoles | 1990 |
Interaction of microsomal cytochrome P-450 isolated from Aspergillus fumigatus with fluconazole and itraconazole.
Topics: Antifungal Agents; Aspergillus fumigatus; Binding, Competitive; Carbon Monoxide; Cytochrome P-450 Enzyme System; Fluconazole; Itraconazole; Ketoconazole; Microsomes; Spectrophotometry | 1990 |
A novel method for studying ergosterol biosynthesis by a cell-free preparation of Aspergillus fumigatus and its inhibition by azole antifungal agents.
Topics: Antifungal Agents; Aspergillus fumigatus; Autoradiography; Azoles; Chromatography, Thin Layer; Ergosterol; Fluconazole; Gas Chromatography-Mass Spectrometry; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Molecular Structure | 1990 |
Suppression of neutrophil and lymphoproliferative responses in vitro by itraconazole but not fluconazole.
Topics: Antifungal Agents; Cells, Cultured; Chemotaxis, Leukocyte; Deoxyglucose; Fluconazole; Humans; Immunosuppressive Agents; Itraconazole; Ketoconazole; Lymphocyte Activation; Neutrophils | 1990 |
Drugs for treatment of fungal infections.
Topics: Amphotericin B; Antifungal Agents; Drug Interactions; Fluconazole; Flucytosine; Humans; Ketoconazole; Mycoses | 1990 |
Fluconazole for ketoconazole-resistant oropharyngeal candidiasis in HIV-1 infected patients.
Topics: Adult; Candidiasis, Oral; Drug Resistance, Microbial; Female; Fluconazole; HIV Infections; HIV-1; Humans; Ketoconazole; Male; Middle Aged; Retrospective Studies | 1990 |
[Comparison of fluconazole and ketoconazole in the therapy of vaginal candidiasis by administration in two different oral doses].
Topics: Candidiasis, Vulvovaginal; Dose-Response Relationship, Drug; Drug Evaluation; Female; Fluconazole; Humans; Ketoconazole | 1990 |
[Trichosporon capitatum septicemia in immunosuppressed patients].
Topics: Adult; Female; Fluconazole; Humans; Immune Tolerance; Ketoconazole; Leukemia, Myeloid, Acute; Male; Middle Aged; Mycoses; Sepsis; Trichosporon | 1990 |
[In vitro activity of fluconazole, a novel bistriazole antifungal agent].
Topics: Animals; Antifungal Agents; Ascitic Fluid; Aspergillus; Candida albicans; Culture Media; Dose-Response Relationship, Drug; Fluconazole; Humans; Hydrogen-Ion Concentration; Ketoconazole; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Triazoles; Yeasts | 1989 |
[Recent antifungal agents].
Topics: Allylamine; Animals; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Morpholines; Mycoses; Triazoles | 1989 |
Comparison of the efficacies of amphotericin B, fluconazole, and itraconazole against a systemic Candida albicans infection in normal and neutropenic mice.
Topics: Agranulocytosis; Amphotericin B; Animals; Antifungal Agents; Candida albicans; Candidiasis; Fluconazole; Half-Life; Itraconazole; Ketoconazole; Male; Mice; Neutropenia; Triazoles | 1989 |
A comparison of fluconazole and ketoconazole in the treatment of rat palatal candidosis.
Topics: Animals; Antifungal Agents; Candidiasis, Oral; Epithelium; Fluconazole; Image Processing, Computer-Assisted; Ketoconazole; Male; Microcomputers; Palate; Rats; Rats, Inbred Strains; Triazoles | 1989 |
A comparative study of the effects of ketoconazole and fluconazole on 17-beta estradiol production by rat ovaries in vitro.
Topics: Animals; Antifungal Agents; Estradiol; Female; Fluconazole; In Vitro Techniques; Ketoconazole; Ovary; Radioimmunoassay; Rats; Rats, Inbred Strains; Triazoles | 1989 |
New triazole antifungal agents (fluconazole and itraconazole) in the treatment of HIV-related gastrointestinal candidiasis.
Topics: Acquired Immunodeficiency Syndrome; Antifungal Agents; Candidiasis; Fluconazole; Gastrointestinal Diseases; Humans; Itraconazole; Ketoconazole; Triazoles | 1989 |
Treatment of experimental zygomycosis in guinea pigs with azoles and with amphotericin B.
Topics: Amphotericin B; Animals; Antifungal Agents; Azoles; Fluconazole; Guinea Pigs; Itraconazole; Ketoconazole; Male; Mucormycosis; Rhizopus; Triazoles | 1989 |
[Treatment of mycoses and new antifungal agents].
Topics: Allylamine; Amphotericin B; Antifungal Agents; Echinocandins; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Mycoses; Naphthalenes; Peptides; Peptides, Cyclic; Terbinafine | 1989 |
[Synergic effect of 5-fluorocytosine and imidazole derivatives against yeast strains resistant to 5-fluorocytosine].
Topics: Antifungal Agents; Candida; Drug Synergism; Fluconazole; Flucytosine; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Yeasts | 1989 |
Genetic and physiological analysis of azole sensitivity in Saccharomyces cerevisiae.
Topics: Cytochrome P-450 Enzyme System; Fluconazole; Ketoconazole; Mutation; Saccharomyces cerevisiae | 1989 |
5-Lipoxygenase inhibition by antifungal azole derivatives: new tools for immunosuppression?
Topics: Antifungal Agents; Arachidonate Lipoxygenases; Fluconazole; Humans; Immunosuppressive Agents; In Vitro Techniques; Itraconazole; Ketoconazole; Lipoxygenase Inhibitors; Neutrophils | 1989 |
Fluconazole versus ketoconazole in oropharyngeal candidiasis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Candidiasis, Oral; Female; Fluconazole; Humans; Ketoconazole; Male; Pharyngeal Diseases; Triazoles | 1989 |
Combination therapy of experimental candidiasis, cryptococcosis, aspergillosis and wangiellosis in mice.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Candidiasis; Cryptococcosis; Drug Therapy, Combination; Exophiala; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Mice; Mycoses; Triazoles | 1987 |
Comparison of two azole antifungal drugs, ketoconazole, and fluconazole, as modifiers of rat hepatic monooxygenase activity.
Topics: Animals; Antifungal Agents; Fluconazole; Ketoconazole; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Substrate Specificity; Testosterone; Triazoles | 1988 |
Activities of fluconazole (UK 49,858) and ketoconazole against ketoconazole-susceptible and -resistant Candida albicans.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Drug Resistance, Microbial; Fluconazole; Ketoconazole; Rabbits; Triazoles | 1988 |
In vitro effects of fluconazole (UK-49,858) and ketoconazole on mouse lymphocyte proliferation and on Candida blastospore destruction by human polymorphonuclear leukocytes.
Topics: Animals; Antifungal Agents; Candida albicans; Cytotoxicity, Immunologic; Fluconazole; Humans; In Vitro Techniques; Ketoconazole; Lymphocyte Activation; Mice; Mice, Inbred Strains; Neutrophils; Spores, Fungal; Triazoles | 1988 |
Primary cutaneous phaeohyphomycosis. Report of three cases.
Topics: Adult; Aged; Aged, 80 and over; Dermatomycoses; Female; Fluconazole; Humans; Immune Tolerance; Ketoconazole; Male; Triazoles | 1988 |
[New antiparasitic drugs].
Topics: Amebicides; Anthelmintics; Antifungal Agents; Antimalarials; Artemisinins; Fluconazole; Humans; Itraconazole; Ketoconazole; Mefloquine; Phenanthrenes; Quinolines; Sesquiterpenes; Triazoles | 1988 |
Use of fluconazole in a patient with documented malabsorption of ketoconazole.
Topics: Administration, Oral; Adult; Antifungal Agents; Candidiasis; Candidiasis, Chronic Mucocutaneous; Female; Fluconazole; Humans; Intestinal Absorption; Ketoconazole; Triazoles | 1988 |
Improved method for azole antifungal susceptibility testing.
Topics: Antifungal Agents; Azoles; Fluconazole; Fungi; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Triazoles | 1988 |
Effects of antimycotic azoles on growth and sterol biosynthesis of Leishmania promastigotes.
Topics: Animals; Antifungal Agents; Chemical Phenomena; Chemistry; Cholesterol; Chromatography, Gas; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Fluconazole; Gas Chromatography-Mass Spectrometry; Itraconazole; Ketoconazole; Leishmania; Leishmania braziliensis; Leishmania donovani; Leishmania mexicana; Leishmania tropica; Sterols; Triazoles | 1988 |
Effects of two oral antimycotics, ketoconazole and fluconazole, upon steroidogenesis in rat adrenal cells in vitro.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Antifungal Agents; Cells, Cultured; Dose-Response Relationship, Drug; Fluconazole; Ketoconazole; Male; Pregnenolone; Rats; Rats, Inbred Strains; Steroids; Triazoles | 1988 |
Effects of azole antifungals in vitro on host/parasite interactions relevant to Candida infections.
Topics: Antifungal Agents; Candida albicans; Cell Adhesion; Clotrimazole; Female; Fluconazole; Humans; Imidazoles; In Vitro Techniques; Ketoconazole; Neutrophils; Phagocytosis; Triazoles; Vagina | 1988 |
Activity of triazole derivatives against Pityrosporum orbiculare in vitro and in vivo.
Topics: Animals; Antifungal Agents; Fluconazole; Itraconazole; Ketoconazole; Malassezia; Rabbits; Structure-Activity Relationship; Tinea Versicolor; Triazoles | 1988 |
The new generation of antifungal drugs.
Topics: Antifungal Agents; Echinocandins; Fluconazole; Humans; Itraconazole; Ketoconazole; Naphthalenes; Peptides; Peptides, Cyclic; Terbinafine; Triazoles | 1988 |
Activity of UK-49,858, a bis-triazole derivative, against experimental infections with Candida albicans and Trichophyton mentagrophytes.
Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Candidiasis, Vulvovaginal; Dermatomycoses; Female; Fluconazole; Guinea Pigs; Immunosuppression Therapy; Ketoconazole; Mice; Rats; Rats, Inbred Strains; Tinea; Triazoles | 1985 |
Penetration of imidazoles and triazoles into cerebrospinal fluid of rabbits.
Topics: Animals; Antifungal Agents; Fluconazole; Itraconazole; Ketoconazole; Meningitis, Haemophilus; Rabbits; Triazoles | 1985 |
Efficacy of UK-49,858 (fluconazole) against Candida albicans experimental infections in mice.
Topics: Amphotericin B; Animals; Antifungal Agents; Candidiasis; Female; Fluconazole; Immune Tolerance; Intestinal Diseases; Ketoconazole; Kinetics; Mice; Triazoles | 1985 |
Comparison of itraconazole and fluconazole in treatment of cryptococcal meningitis and candida pyelonephritis in rabbits.
Topics: Animals; Candidiasis; Cortisone; Cryptococcosis; Dose-Response Relationship, Drug; Fluconazole; Immunity; Itraconazole; Ketoconazole; Meningitis; Pyelonephritis; Rabbits; Triazoles | 1986 |
Treatment of murine coccidioidal meningitis with fluconazole (UK 49,858).
Topics: Amphotericin B; Animals; Antifungal Agents; Coccidioides; Coccidioidomycosis; Fluconazole; Ketoconazole; Male; Meningitis; Mice; Mice, Inbred ICR; Triazoles | 1986 |
Azole resistance in Candida albicans.
Topics: Adult; Animals; Antifungal Agents; Candida albicans; Candidiasis; Candidiasis, Chronic Mucocutaneous; Disease Models, Animal; Drug Resistance, Microbial; Econazole; Female; Fluconazole; Guinea Pigs; Humans; Imidazoles; Itraconazole; Ketoconazole; Male; Mice; Miconazole; Rats; Rats, Inbred Strains; Triazoles | 1986 |
Treatment of cryptococcal meningitis in mice with fluconazole.
Topics: Amphotericin B; Animals; Antifungal Agents; Cryptococcosis; Fluconazole; Ketoconazole; Kinetics; Meningitis; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Nude; Rats; Rats, Inbred Strains; Triazoles | 1986 |
Treatment of murine histoplasmosis with UK 49,858 (fluconazole).
Topics: Animals; Antifungal Agents; Female; Fluconazole; Histoplasmosis; Ketoconazole; Lung Diseases, Fungal; Male; Mice; Mice, Inbred ICR; Mice, Nude; Triazoles | 1986 |
Activity of fluconazole (UK 49,858) and ketoconazole against Candida albicans in vitro and in vivo.
Topics: Animals; Antifungal Agents; Buffers; Candida albicans; Culture Media; Fluconazole; Fungal Proteins; Hydrogen-Ion Concentration; Ketoconazole; Male; Microbial Sensitivity Tests; Rats; Rats, Inbred Strains; Triazoles | 1986 |
Penetration of new azole compounds into the eye and efficacy in experimental Candida endophthalmitis.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Endophthalmitis; Eye; Fluconazole; Itraconazole; Ketoconazole; Kinetics; Male; Rabbits; Tissue Distribution; Triazoles | 1987 |
Action of fluconazole (UK-49,858) in relation to other systemic antifungal azoles.
Topics: Antifungal Agents; Candida; Candida albicans; Fluconazole; Ketoconazole; Miconazole; Triazoles | 1987 |
Fungistatic and fungicidal effects of amphotericin B, ketoconazole and fluconazole (UK 49,858) against histoplasma capsulatum in vitro and in vivo.
Topics: Amphotericin B; Animals; Antifungal Agents; Culture Techniques; Fluconazole; Histoplasma; Histoplasmosis; Ketoconazole; Male; Mice; Triazoles | 1987 |
Efficacy of fluconazole (UK-49,858) against experimental aspergillosis and cryptococcosis in mice.
Topics: Amphotericin B; Animals; Antifungal Agents; Aspergillosis; Aspergillus flavus; Aspergillus fumigatus; Brain Diseases; Cryptococcosis; Female; Fluconazole; Ketoconazole; Lung Diseases, Fungal; Mice; Opportunistic Infections; Triazoles | 1987 |
Effects of bifonazole, fluconazole, itraconazole, and terbinafine on the chemiluminescence response of immune cells.
Topics: Animals; Antifungal Agents; Cell Survival; Centrifugation; Fluconazole; Imidazoles; In Vitro Techniques; Itraconazole; Ketoconazole; Luminescent Measurements; Luminol; Mice; Mice, Inbred BALB C; Naphthalenes; Phagocytes; Rabbits; Rifampin; Spleen; Terbinafine; Triazoles | 1987 |
Drugs for AIDS and associated infections.
Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Antiprotozoal Agents; Antiviral Agents; Atovaquone; Candidiasis, Oral; Clindamycin; Clotrimazole; Cryptosporidiosis; Cytomegalovirus Infections; Dapsone; Didanosine; Drug Combinations; Drug Therapy, Combination; Fluconazole; Flucytosine; Folic Acid Antagonists; Foscarnet; Glucuronates; Herpes Simplex; Herpes Zoster; Humans; Isoniazid; Itraconazole; Ketoconazole; Lamivudine; Mycobacterium avium-intracellulare Infection; Naphthoquinones; Nystatin; Pentamidine; Pneumocystis Infections; Pneumonia, Pneumocystis; Prednisone; Primaquine; Reverse Transcriptase Inhibitors; Stavudine; Syphilis; Toxoplasmosis; Trimetrexate; Tuberculosis; Zalcitabine; Zidovudine | 1995 |
Effect of azoles on the glucuronidation of zidovudine by human liver UDP-glucuronosyltransferase.
Topics: Antifungal Agents; Antiviral Agents; Drug Interactions; Fluconazole; Glucuronosyltransferase; Humans; Itraconazole; Ketoconazole; Liver; Zidovudine | 1995 |
Resistance to azole drugs in Neurospora crassa.
Topics: Antifungal Agents; Crosses, Genetic; Drug Resistance, Microbial; Fluconazole; Ketoconazole; Meiosis; Mutagenesis; Neurospora crassa; Selection, Genetic; Triazoles | 1995 |
Resistant P45051A1 activity in azole antifungal tolerant Cryptococcus neoformans from AIDS patients.
Topics: AIDS-Related Opportunistic Infections; Cryptococcosis; Cryptococcus neoformans; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Microbial; Drug Tolerance; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Microsomes; Oxidoreductases; Sterol 14-Demethylase; Sterols; Treatment Failure | 1995 |
[Post-antibiotic effect and post-exposure polyene antagonism of azole antimycotics in Candida albicans: dependency on lipophilia].
Topics: Amphotericin B; Candida albicans; Drug Interactions; Fluconazole; Itraconazole; Ketoconazole; Lipids; Miconazole; Microbial Sensitivity Tests; Structure-Activity Relationship | 1995 |
Increased resistance to antifungal antibiotics of Candida spp. adhered to silicone.
Topics: Amphotericin B; Antifungal Agents; Biofilms; Candida; Candidiasis; Cell Adhesion; Drug Resistance, Microbial; Fluconazole; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Miconazole; Silicones; Urinary Catheterization | 1995 |
Cloning and stable expression of the human mitochondrial cytochrome P45011B1 cDNA in V79 Chinese hamster cells and their application for testing of potential inhibitors.
Topics: Adrenal Glands; Animals; Base Sequence; Cell Line; Cloning, Molecular; Clotrimazole; Cricetinae; Cricetulus; DNA Primers; DNA, Complementary; Fluconazole; Gene Expression; Hydrocortisone; Hydroxylation; Ketoconazole; Kinetics; Metyrapone; Miconazole; Mitochondria; Molecular Sequence Data; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Spironolactone; Steroid 11-beta-Hydroxylase; Transfection | 1995 |
Comparison of Etest and National Committee for Clinical Laboratory Standards broth macrodilution method for azole antifungal susceptibility testing.
Topics: Antifungal Agents; Candida; Cryptococcus neoformans; Double-Blind Method; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Prospective Studies; Sensitivity and Specificity | 1995 |
In vitro activity of D0870 compared with those of other azoles against fluconazole-resistant Candida spp.
Topics: Antifungal Agents; Candida; Drug Resistance, Microbial; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Triazoles | 1995 |
A comparison of susceptibility to five antifungal agents of yeast cultures from burn patients.
Topics: Amphotericin B; Antifungal Agents; Burns; Candida; Drug Resistance, Microbial; Fluconazole; Flucytosine; Humans; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Trichosporon; Yeasts | 1995 |
Fluconazole, itraconazole and ketoconazole in vitro activity against Candida spp.
Topics: Candida; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 1994 |
Comparison of ketoconazole- and fluconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes.
Topics: Analysis of Variance; Animals; Cell Membrane Permeability; Cells, Cultured; Fluconazole; Ketoconazole; L-Lactate Dehydrogenase; Liver; Lysosomes; Mitochondria, Liver; Neutral Red; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1995 |
Comparison of broth dilution and semisolid agar dilution for in vitro susceptibility testing of Cryptococcus neoformans.
Topics: Amphotericin B; Antifungal Agents; Blood; Cerebrospinal Fluid; Cryptococcus neoformans; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Skin | 1994 |
Pneumocystis carinii is resistant to imidazole antifungal agents.
Topics: Animals; Antifungal Agents; Ergosterol; Female; Fluconazole; Gas Chromatography-Mass Spectrometry; Itraconazole; Ketoconazole; Miconazole; Pneumocystis; Rats; Rats, Sprague-Dawley; Triazoles | 1994 |
Fungemia and colonization with nystatin-resistant Candida rugosa in a burn unit.
Topics: Amphotericin B; Burn Units; Burns; Candida; Candidiasis; Case-Control Studies; Cross Infection; Fluconazole; Flucytosine; Humans; Ketoconazole; Microbial Sensitivity Tests; Nystatin; Retrospective Studies | 1994 |
Ro 09-1470 is a selective inhibitor of P-450 lanosterol C-14 demethylase of fungi.
Topics: Animals; Antifungal Agents; Carbon Monoxide; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fluconazole; Fungal Proteins; Glycine; Heme; Ketoconazole; Liver; Male; Microsomes, Liver; Oxidoreductases; Pyrans; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae; Sensitivity and Specificity; Sterol 14-Demethylase | 1993 |
Ketoconazole and fluconazole drug interactions.
Topics: Antifungal Agents; Arrhythmias, Cardiac; Astemizole; Drug Interactions; Fluconazole; Humans; Ketoconazole; Terfenadine | 1994 |
Neonatal renal candidiasis.
Topics: Amphotericin B; Candidiasis; Diagnostic Imaging; Drug Therapy, Combination; Fluconazole; Humans; Infant; Ketoconazole; Male; Pyelonephritis; Ureteral Obstruction | 1994 |
Severe candidal infections in neutropenic patients.
Topics: Amphotericin B; Candidiasis; Fluconazole; Humans; Itraconazole; Ketoconazole; Neutropenia | 1993 |
Fluconazole-resistant Candida in AIDS patients. Report of two cases.
Topics: Adult; AIDS-Related Opportunistic Infections; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Fluconazole; Humans; Ketoconazole; Male | 1993 |
Systemic antifungal drugs.
Topics: Amphotericin B; Antifungal Agents; Drug Interactions; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Mycoses | 1994 |
Cost-effective treatment of Candida esophagitis.
Topics: Candidiasis; Esophagitis; Fluconazole; Humans; Ketoconazole | 1993 |
Successful treatment of Trypanosoma cruzi encephalitis in a patient with hemophilia and AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Chagas Disease; Drug Therapy, Combination; Encephalitis; Fluconazole; Hemophilia A; Humans; Itraconazole; Ketoconazole; Male; Nitroimidazoles; Transfusion Reaction; Trypanocidal Agents | 1993 |
Management of persistent vulvo vaginal candidosis due to azole-resistant Candida glabrata.
Topics: Administration, Oral; Administration, Topical; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Drug Resistance, Microbial; Econazole; Female; Fluconazole; Gentian Violet; Humans; Itraconazole; Ketoconazole; Medroxyprogesterone Acetate; Microbial Sensitivity Tests; Nystatin | 1993 |
Histoplasmosis in the acquired immunodeficiency syndrome (AIDS): treatment with itraconazole and fluconazole.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Amphotericin B; Antifungal Agents; Fluconazole; Histoplasmosis; Humans; Itraconazole; Ketoconazole; Middle Aged; Retrospective Studies; Treatment Outcome | 1993 |
[Strategy for examination and therapy of mycotic keratitis].
Topics: Acremonium; Administration, Oral; Adolescent; Amphotericin B; Antifungal Agents; Contact Lenses; Drug Therapy, Combination; Female; Fluconazole; Humans; Itraconazole; Keratitis; Ketoconazole; Mycoses; Ophthalmic Solutions; Therapeutic Irrigation | 1993 |
Pharmacokinetics of antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Flucytosine; Humans; Ketoconazole; Mycoses; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis | 1993 |
Cost-effective treatment of Candida esophagitis.
Topics: Candidiasis; Esophagitis; Fluconazole; Humans; Ketoconazole | 1993 |
Cost-effective treatment of Candida esophagitis.
Topics: Candidiasis; Drug Costs; Esophagitis; Fluconazole; Humans; Ketoconazole | 1993 |
Comparative effects of antifungal agents on zidovudine glucuronidation by human liver microsomes.
Topics: Amphotericin B; Antifungal Agents; Antiviral Agents; Chromatography, High Pressure Liquid; Fluconazole; Flucytosine; Glucuronates; Humans; Itraconazole; Ketoconazole; Miconazole; Microsomes, Liver; Zidovudine | 1995 |
Systemic antifungal drugs.
Topics: Amphotericin B; Antifungal Agents; Drug Interactions; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Mycoses | 1996 |
Azole drug resistance in yeasts.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Azoles; Candidiasis; Drug Resistance, Microbial; Fluconazole; Humans; Itraconazole; Ketoconazole; Mycoses | 1995 |
Antifungal susceptibility testing using the E test: comparison with the broth macrodilution technique.
Topics: Antifungal Agents; Candida; Cryptococcus neoformans; Culture Media; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Reproducibility of Results | 1996 |
Comparison of ketoconazole and fluconazole as cytochrome P450 inhibitors. Use of steady-state infusion approach to achieve plasma concentration-response relationships.
Topics: Animals; Antifungal Agents; Antipyrine; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluconazole; Infusion Pumps; Ketoconazole; Liver; Male; Metabolic Clearance Rate; Rats; Rats, Sprague-Dawley | 1996 |
Multisite reproducibility of the Etest MIC method for antifungal susceptibility testing of yeast isolates.
Topics: Amphotericin B; Antifungal Agents; Candida; Evaluation Studies as Topic; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Quality Control; Reproducibility of Results | 1996 |
New model of oropharyngeal and gastrointestinal colonization by Candida albicans in CD4+ T-cell-deficient mice for evaluation of antifungal agents.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antifungal Agents; Candida albicans; CD4-Positive T-Lymphocytes; Digestive System; Disease Models, Animal; Female; Fluconazole; Ketoconazole; Mice; Mice, Inbred DBA; Microbial Sensitivity Tests; Nystatin; Oropharynx; Peptides; Peptides, Cyclic | 1996 |
Correlation between rhodamine 123 accumulation and azole sensitivity in Candida species: possible role for drug efflux in drug resistance.
Topics: Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azoles; Candida; Drug Resistance, Microbial; Fluconazole; Fluorescent Dyes; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Rhodamine 123; Rhodamines | 1996 |
[Clinical fluconazole and itraconazole resistance of oro-gastrointestinal candidiasis in a patient with AIDS].
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis; Candidiasis, Oral; Drug Resistance, Multiple; Drug Therapy, Combination; Fluconazole; Flucytosine; Gastrointestinal Diseases; Humans; Ketoconazole; Male; Microbial Sensitivity Tests | 1996 |
Rationalizing prescribing for oral and oesophageal candidiasis.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis; Candidiasis, Oral; Drug Costs; Esophageal Diseases; Fluconazole; Humans; Ketoconazole; Medical Audit; Practice Guidelines as Topic; Retrospective Studies | 1996 |
Inhibition of mitochondrial function in isolated rate liver mitochondria by azole antifungals.
Topics: Animals; Antifungal Agents; Dose-Response Relationship, Drug; Fluconazole; In Vitro Techniques; Ketoconazole; Male; Miconazole; Mitochondria, Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Oxidative Phosphorylation; Rats; Succinate Dehydrogenase | 1996 |
[White piedra. Report of a case].
Topics: Adolescent; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Piedra; Scalp Dermatoses; Trichosporon | 1996 |
A disc plate assay for characterization of the effect of interaction between polyenes and azoles on growth of Candida albicans CA12.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Drug Antagonism; Fluconazole; Ketoconazole; Microbial Sensitivity Tests | 1996 |
Biotransformation of mestranol to ethinyl estradiol in vitro: the role of cytochrome P-450 2C9 and metabolic inhibitors.
Topics: Adult; Antifungal Agents; Biotransformation; Cells, Cultured; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Estradiol Congeners; Ethinyl Estradiol; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Mestranol; Microsomes, Liver | 1997 |
Characterization of Saccharomyces cerevisiae CYP61, sterol delta22-desaturase, and inhibition by azole antifungal agents.
Topics: Antifungal Agents; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ergosterol; Fluconazole; Ketoconazole; Oxidoreductases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Spectrophotometry, Atomic; Sterol 14-Demethylase | 1997 |
Reduced intracellular accumulation of azole antifungal results in resistance in Candida albicans isolate NCPF 3363.
Topics: Antifungal Agents; Candida albicans; Candidiasis, Chronic Mucocutaneous; Drug Resistance, Microbial; Fluconazole; Ketoconazole; Microbial Sensitivity Tests; Sterols | 1997 |
Effect of pH and buffer system on the in-vitro activity of five antifungals against yeasts.
Topics: Amphotericin B; Antifungal Agents; Buffers; Candida; Culture Media; Fluconazole; Flucytosine; Fungi; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Reproducibility of Results; Species Specificity; Spectrophotometry | 1997 |
Chronic Candida albicans otitis media in children with immunodeficiency.
Topics: Antifungal Agents; Candidiasis; Child; Child, Preschool; Chronic Disease; Diagnosis, Differential; Female; Fluconazole; Humans; Immunocompromised Host; Immunoglobulins, Intravenous; Ketoconazole; Otitis Media, Suppurative | 1997 |
Rapid high performance liquid chromatographic assay for antifungal agents in human sera.
Topics: Amphotericin B; Antifungal Agents; Chromatography, High Pressure Liquid; Econazole; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Spectrophotometry, Ultraviolet | 1996 |
Increased mRNA levels of ERG16, CDR, and MDR1 correlate with increases in azole resistance in Candida albicans isolates from a patient infected with human immunodeficiency virus.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Biological Transport; Candida albicans; Drug Resistance, Microbial; Fluconazole; Genes, Fungal; Genes, MDR; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; RNA, Messenger | 1997 |
Ketoconazole and fluconazole inhibition of the metabolism of cyclosporin A by human liver in vitro.
Topics: Adult; Antifungal Agents; Antirheumatic Agents; Chromatography, High Pressure Liquid; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluconazole; Humans; Ketoconazole; Liver; Male; Microsomes, Liver; Middle Aged | 1997 |
Candidal colonization and oral candidiasis in patients undergoing oral and pharyngeal radiation therapy.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antifungal Agents; Candida albicans; Candidiasis, Oral; Carcinoma, Squamous Cell; Colony Count, Microbial; Cranial Irradiation; Female; Fluconazole; Humans; Ketoconazole; Logistic Models; Male; Middle Aged; Odds Ratio; Oropharyngeal Neoplasms; Smoking; Statistics, Nonparametric; Xerostomia | 1997 |
Outpatient therapy of HIV-associated oral and oesophageal candidosis.
Topics: AIDS-Related Opportunistic Infections; Ambulatory Care; Amphotericin B; Antifungal Agents; Candidiasis, Oral; Esophagitis; Fluconazole; Guidelines as Topic; Humans; Itraconazole; Ketoconazole; Medical Audit; Nystatin; Retrospective Studies | 1997 |
Systemic antifungal drugs.
Topics: Amphotericin B; Anorexia; Antifungal Agents; Aspergillosis; Blastomycosis; Candidiasis; Coccidioidomycosis; Cryptococcosis; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Fluconazole; Flucytosine; Gynecomastia; Histoplasmosis; Humans; Itraconazole; Ketoconazole; Kidney Diseases; Liposomes; Male; Mixed Function Oxygenases; Mucormycosis; Nausea; Paracoccidioidomycosis; Sporotrichosis; Teratogens | 1997 |
[In vitro susceptibility to antifungal agents of Candida strains isolated from patients with various diseases of the respiratory tract].
Topics: Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Candida; Candidiasis; Fluconazole; Flucytosine; Humans; Ketoconazole; Microbial Sensitivity Tests; Middle Aged; Nystatin; Respiratory Tract Infections; Species Specificity; Sputum | 1997 |
Unresponsive HIV-related oro-oesophageal candidosis--an evaluation of two new in-vitro azole susceptibility tests.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candidiasis, Oral; Drug Resistance, Microbial; Esophageal Diseases; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 1997 |
Prediction of relapse after treatment of coccidioidomycosis.
Topics: Adolescent; Adult; Amphotericin B; Antifungal Agents; Coccidioidomycosis; Cohort Studies; Female; Fluconazole; Follow-Up Studies; Humans; Ketoconazole; Male; Middle Aged; Predictive Value of Tests; Recurrence; Retrospective Studies | 1997 |
Clinically significant azole cross-resistance in Candida isolates from HIV-positive patients with oral candidosis.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluconazole; Humans; Itraconazole; Ketoconazole | 1997 |
[Effect of keratin on the efficacy of fluconazole].
Topics: Animals; Antifungal Agents; Blood Proteins; Fluconazole; Itraconazole; Keratins; Ketoconazole; Kinetics; Sheep; Skin; Wool | 1997 |
[Fluconazole-resistant Candida species from HIV infected patients with recurrent Candida stomatitis: cross resistance to itraconazole and ketoconazole].
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Recurrence | 1997 |
Effects of three azole derivatives on the lipids of different strains of Sporothrix schenckii.
Topics: Antifungal Agents; Fluconazole; Itraconazole; Ketoconazole; Lanosterol; Lipids; Sporothrix | 1997 |
[Evaluation of the E-test: comparison of E-test and microbroth dilution method in azole antifungal susceptibility test].
Topics: Antifungal Agents; Candida albicans; Fluconazole; Indicator Dilution Techniques; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Reproducibility of Results | 1998 |
Antimicrobial susceptibility patterns of fungi isolated from horses with ulcerative keratomycosis.
Topics: Analysis of Variance; Animals; Antifungal Agents; Aspergillus; Cornea; Corneal Ulcer; Drug Resistance, Microbial; Eye Infections, Fungal; Fluconazole; Fungi; Fusarium; Horse Diseases; Horses; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Natamycin; Penicillium | 1998 |
Clinical predictors of azole resistance, outcome and survival from oesophageal candidiasis in AIDS patients.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Body Weight; Candidiasis; CD4 Lymphocyte Count; Drug Resistance, Microbial; Esophageal Diseases; Female; Fluconazole; Humans; Ketoconazole; Male; Retrospective Studies; Survivors; Treatment Outcome | 1998 |
Susceptibilities of clinical and laboratory isolates of Blastomyces dermatitidis to ketoconazole, itraconazole, and fluconazole.
Topics: Antifungal Agents; Blastomyces; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 1998 |
Comparison of a 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-[(phenylamino)carbonyl]-2H-t etrazolium hydroxide (XTT) colorimetric method with the standardized National Committee for Clinical Laboratory Standards method of testing clinical yeast isolates for
Topics: Amphotericin B; Antifungal Agents; Candida; Colorimetry; Cryptococcus; Evaluation Studies as Topic; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 1998 |
Nosocomial breakthrough fungaemia during antifungal prophylaxis or empirical antifungal therapy in 41 cancer patients receiving antineoplastic chemotherapy: analysis of aetiology risk factors and outcome.
Topics: Amphotericin B; Antifungal Agents; Antineoplastic Agents; Cross Infection; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Fluconazole; Fungemia; Humans; Incidence; Itraconazole; Ketoconazole; Male; Mitosporic Fungi; Neoplasms; Pichia; Retrospective Studies; Risk Factors; Slovakia; Treatment Outcome | 1998 |
The effect of limited exposure to antifungal agents on the germ tube formation of oral Candida albicans.
Topics: Adhesiveness; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Candida albicans; Candidiasis, Oral; Culture Media; Dose-Response Relationship, Drug; Fluconazole; Flucytosine; HIV Seronegativity; Humans; Ketoconazole; Microscopy, Electron, Scanning; Mouth; Nystatin | 1998 |
Effect of metabolic inhibitors on cyclosporine pharmacokinetics using a population approach.
Topics: Administration, Oral; Adolescent; Adult; Aged; Antifungal Agents; Calcium Channel Blockers; Child; Cyclosporine; Diltiazem; Drug Administration Schedule; Drug Interactions; Fluconazole; Heart-Lung Transplantation; Humans; Immunosuppressive Agents; Individuality; Itraconazole; Ketoconazole; Linear Models; Middle Aged | 1998 |
Adhesion of oral C. albicans to human buccal epithelial cells following limited exposure to antifungal agents.
Topics: Antifungal Agents; Candida albicans; Cell Adhesion; Cheek; Epithelial Cells; Female; Fluconazole; Flucytosine; Humans; Ketoconazole; Male; Microscopy, Electron, Scanning; Mouth Mucosa; Nystatin | 1998 |
Blastomycosis in dogs: 115 cases (1980-1995).
Topics: Age Distribution; Amphotericin B; Animals; Antibodies, Fungal; Antifungal Agents; Blastomyces; Blastomycosis; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Fluconazole; Housing, Animal; Immunodiffusion; Itraconazole; Ketoconazole; Louisiana; Male; Radiography, Thoracic; Retrospective Studies; Seasons; Treatment Outcome | 1998 |
Synergy of nitric oxide and azoles against Candida species in vitro.
Topics: Antifungal Agents; Candida; Drug Synergism; Fluconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Triazenes | 1998 |
Voriconazole against fluconazole-susceptible and resistant candida isolates: in-vitro efficacy compared with that of itraconazole and ketoconazole.
Topics: Antifungal Agents; Candida; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 1998 |
Study of the susceptibility of yeast isolates of clinical interest to five antifungal agents using the E test.
Topics: Amphotericin B; Antifungal Agents; Candida; Cryptococcus neoformans; Drug Resistance, Microbial; Fluconazole; Flucytosine; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Prototheca | 1998 |
Adhesion of oral Candida albicans isolates to denture acrylic following limited exposure to antifungal agents.
Topics: Adhesiveness; Administration, Topical; Amphotericin B; Analysis of Variance; Antifungal Agents; Candida albicans; Candidiasis, Oral; Denture Bases; Drug Administration Schedule; Fluconazole; Flucytosine; Humans; Image Processing, Computer-Assisted; Ketoconazole; Mouth; Nystatin; Polymethyl Methacrylate; Stomatitis, Denture; Surface Properties; Time Factors | 1998 |
Azole resistance among oral Candida species isolates from AIDS patients under ketoconazole exposure.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Antifungal Agents; Azoles; Brazil; Candida albicans; Candidiasis, Oral; Drug Resistance, Microbial; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Mouth Mucosa; Mycology; Prevalence; Prospective Studies; Statistics, Nonparametric | 1998 |
Antifungal susceptibility of Candida isolates at the American University of Beirut Medical Center.
Topics: Amphotericin B; Antifungal Agents; Candida; Candida albicans; Candidiasis; Fluconazole; Flucytosine; Hospitals, University; Humans; Itraconazole; Ketoconazole; Lebanon; Microbial Sensitivity Tests | 1998 |
Inhibition of cytochrome P-450 3A (CYP3A) in human intestinal and liver microsomes: comparison of Ki values and impact of CYP3A5 expression.
Topics: Algorithms; Antifungal Agents; Blotting, Western; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA, Complementary; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; In Vitro Techniques; Intestine, Small; Ketoconazole; Kinetics; Microsomes; Microsomes, Liver; Midazolam; Mixed Function Oxygenases | 1999 |
Trends in antifungal use and epidemiology of nosocomial yeast infections in a university hospital.
Topics: Adult; Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Candidiasis; Cross Infection; Fluconazole; Hospitals, University; Humans; Incidence; Intensive Care Units; Iowa; Ketoconazole; Medical Records; Postoperative Complications | 1999 |
Multicenter comparison of the sensititre YeastOne Colorimetric Antifungal Panel with the National Committee for Clinical Laboratory standards M27-A reference method for testing clinical isolates of common and emerging Candida spp., Cryptococcus spp., and
Topics: Amphotericin B; Antifungal Agents; Candida; Colorimetry; Cryptococcus; Fluconazole; Flucytosine; Guidelines as Topic; Itraconazole; Ketoconazole; Laboratories; Microbial Sensitivity Tests; Quality Assurance, Health Care; Reference Standards; Yeasts | 1999 |
Effects of azole antifungal drugs on the transition from yeast cells to hyphae in susceptible and resistant isolates of the pathogenic yeast Candida albicans.
Topics: Antifungal Agents; Azoles; Candida albicans; Cell Division; Drug Resistance, Microbial; Fluconazole; Humans; Ketoconazole; Methionine; Sulfur Radioisotopes | 1999 |
The postantifungal effect (PAFE) of antimycotics on oral C. albicans isolates and its impact on candidal adhesion.
Topics: Acrylic Resins; Amphotericin B; Analysis of Variance; Antifungal Agents; Candida albicans; Cell Adhesion; Denture Bases; Fluconazole; Flucytosine; Ketoconazole; Microbial Sensitivity Tests; Nystatin | 1998 |
Comparison of the toxicity of fluconazole and other azole antifungal drugs to murine and human granulocyte-macrophage progenitor cells in vitro.
Topics: Animals; Antifungal Agents; Azoles; Bone Marrow; Cells, Cultured; Clotrimazole; Dose-Response Relationship, Drug; Econazole; Female; Fluconazole; Granulocytes; Hematopoietic Stem Cells; Humans; Imidazoles; Inhibitory Concentration 50; Ketoconazole; Macrophages; Male; Mice; Miconazole; Species Specificity; Stem Cells | 1999 |
In-vitro resistance to azoles associated with mitochondrial DNA deficiency in Candida glabrata.
Topics: Antifungal Agents; Azoles; Candida; Candidiasis; Clotrimazole; DNA, Fungal; DNA, Mitochondrial; Drug Resistance, Microbial; Econazole; Electrophoresis, Agar Gel; Fluconazole; Humans; Imidazoles; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Polyenes | 1999 |
[Epidemiology of fungemia in a university hospital; therapeutic incidence].
Topics: Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Child, Preschool; Female; Fluconazole; France; Fungemia; Hospitals, University; Humans; Infant; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Mycoses; Postoperative Complications; Saccharomyces cerevisiae | 1999 |
Comparative evaluation of Fungitest-, Neo-Sensitabs- and M27T-NCCLS broth microdilution methods for antifungal drug susceptibility testing of Candida species and Cryptococcus neoformans.
Topics: Amphotericin B; Antifungal Agents; Candida; Cryptococcus neoformans; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Reagent Kits, Diagnostic | 1999 |
Quantitative drug interactions prediction system (Q-DIPS): a computer-based prediction and management support system for drug metabolism interactions.
Topics: Antifungal Agents; Computer Simulation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Data Collection; Databases as Topic; Drug Interactions; Enzyme Inhibitors; Fluconazole; Ketoconazole; Mixed Function Oxygenases; Pharmaceutical Preparations | 1999 |
Multiple amino acid substitutions in lanosterol 14alpha-demethylase contribute to azole resistance in Candida albicans.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antifungal Agents; Candida albicans; Cytochrome P-450 Enzyme System; Drug Resistance, Microbial; Drug Resistance, Multiple; Fluconazole; Ketoconazole; Molecular Sequence Data; Mutation; Oxidoreductases; Saccharomyces cerevisiae; Sequence Alignment; Sterol 14-Demethylase | 1999 |
[Determination of the in vitro antifungal susceptibility of clinically important yeasts using the Sensititre system].
Topics: Amphotericin B; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Yeasts | 1999 |
[Disseminated histoplasmosis caused by Histoplasma capsulatum with cerebral involvement occurring 13 years after the primary infection].
Topics: Antifungal Agents; Brain; Brain Diseases; Central Nervous System Fungal Infections; Fluconazole; Histoplasmosis; Humans; Ketoconazole; Lung Diseases, Fungal; Male; Middle Aged; Radiography, Thoracic; Time Factors; Tomography, X-Ray Computed | 1999 |
The use of systemic antimycotics in dermatotherapy.
Topics: Administration, Cutaneous; Administration, Oral; Antifungal Agents; Cost-Benefit Analysis; Dermatomycoses; Fluconazole; Griseofulvin; Hair Diseases; Humans; Itraconazole; Ketoconazole; Naphthalenes; Odds Ratio; Onychomycosis; Terbinafine; Tinea | 2000 |
Evaluation of a capacitance method for direct antifungal susceptibility testing of yeasts in positive blood cultures.
Topics: Amphotericin B; Antifungal Agents; Blood; Candida; Candida albicans; Culture Media; Drug Resistance, Microbial; Fluconazole; Flucytosine; Humans; Ketoconazole; Microbial Sensitivity Tests; Reproducibility of Results | 2000 |
Inhibitory effect of azole antifungal agents on the glucuronidation of lorazepam using rabbit liver microsomes in vitro.
Topics: Animals; Anti-Anxiety Agents; Antifungal Agents; Azoles; Binding, Competitive; Detergents; Fluconazole; Glucuronic Acid; In Vitro Techniques; Ketoconazole; Kinetics; Lorazepam; Male; Miconazole; Microsomes, Liver; Rabbits; Uridine Diphosphate Glucuronic Acid | 2000 |
Effects of amphotericin B and three azole derivatives on the lipids of yeast cells of Paracoccidioides brasiliensis.
Topics: Amphotericin B; Antifungal Agents; Azoles; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Paracoccidioides; Sterols | 2000 |
Quantitative prediction of in vivo drug interactions between nevirapine and antifungal agents from in vitro data in rats.
Topics: Albumins; Animals; Anti-HIV Agents; Antifungal Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Fluconazole; Ketoconazole; Male; Microsomes, Liver; Nevirapine; Oxidoreductases, N-Demethylating; Rats; Rats, Sprague-Dawley | 2000 |
Susceptibility testing of Candida species: comparison of NCCLS microdilution method with Fungitest.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Resistance, Microbial; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests | 2000 |
The combination of oral amphotericin B with azoles prevents the emergence of resistant Candida species in neutropenic patients.
Topics: Amphotericin B; Antifungal Agents; Azoles; Bone Marrow Transplantation; Candida; Candidiasis; Drug Resistance, Microbial; Drug Therapy, Combination; Fluconazole; Hematologic Neoplasms; Humans; Itraconazole; Ketoconazole; Neutropenia; Prospective Studies; Retrospective Studies | 2001 |
Influence of pH and concentration on the postantifungal effect and on the effects of sub-MIC concentrations of 4 antifungal agents on previously treated Candida spp.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Resistance, Fungal; Fluconazole; Flucytosine; Hydrogen-Ion Concentration; Ketoconazole; Microbial Sensitivity Tests; Time Factors | 2000 |
Determination of minumum inhibitory concentrations of Candida species isolated from vaginal swab specimens by using broth macrodilution and E-test.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis, Vulvovaginal; Female; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Vagina | 2001 |
Effect of ketoconazole, itraconazole and fluconazole on the gastrointestinal colonization of mice by Candida albicans.
Topics: Animals; Antifungal Agents; Azoles; Candida albicans; Candidiasis; Digestive System; Fluconazole; Itraconazole; Ketoconazole; Mice | 2001 |
In-vitro activity of five antifungal agents against uncommon clinical isolates of Candida spp.
Topics: Amphotericin B; Antifungal Agents; Candida; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 1999 |
Anti leishmanial therapy--the changing scene.
Topics: Antifungal Agents; Fluconazole; Humans; Ketoconazole; Leishmaniasis | 1995 |
Treatment for coccidioidomycosis in pregnancy?
Topics: Amphotericin B; Antifungal Agents; Coccidioidomycosis; Erythema Nodosum; Female; Fluconazole; Humans; Ketoconazole; Patient Selection; Pregnancy; Pregnancy Complications, Infectious; Risk Factors | 2001 |
Oropharyngeal candidiasis in patients with human immunodeficiency virus: correlation of clinical outcome with in vitro resistance, serum azole levels, and immunosuppression.
Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Candidiasis; Child; Drug Resistance, Microbial; Female; Fluconazole; HIV-1; Humans; Immune Tolerance; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Oropharynx; Pharyngeal Diseases | 2001 |
Candidiasis at ICAAC.
Topics: Administration, Oral; AIDS-Related Opportunistic Infections; Antifungal Agents; Biological Availability; Candida albicans; Candidiasis, Oral; Clinical Trials as Topic; Drug Resistance, Microbial; Fluconazole; HIV; Humans; Itraconazole; Ketoconazole; Mutation | 1995 |
Histoplasmosis: update 1998.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Central Nervous System Diseases; Clinical Trials as Topic; Dosage Forms; Fluconazole; Histoplasmosis; Itraconazole; Ketoconazole; Remission Induction | 1998 |
[Endemic mycotic infections].
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Blastomycosis; Coccidioidomycosis; Diagnosis, Differential; Fluconazole; Histoplasmosis; Humans; Itraconazole; Ketoconazole; Travel | 2001 |
Heterogeneity in antifungal susceptibility of clones of Candida albicans isolated on single and sequential visits from a HIV-infected southern Chinese cohort.
Topics: Adult; AIDS-Related Opportunistic Infections; Amphotericin B; Analysis of Variance; Antifungal Agents; Candida albicans; Candidiasis, Oral; China; Cohort Studies; Drug Resistance, Microbial; Ethnicity; Female; Fluconazole; Follow-Up Studies; HIV Infections; Humans; Ketoconazole; Male; Middle Aged; Oropharynx; Pharyngeal Diseases; Recurrence | 2001 |
Application of capillary zone electrophoresis with off-line solid-phase extraction to in vitro metabolism studies of antifungals.
Topics: Acetic Acid; Acetonitriles; Antifungal Agents; Clotrimazole; Drug Stability; Electrophoresis, Capillary; Fluconazole; Humans; Itraconazole; Ketoconazole; Methanol; Microsomes, Liver; Molecular Structure; Molecular Weight; Pyrimidines; Reproducibility of Results; Sensitivity and Specificity; Solvents; Triazoles; Verapamil; Voriconazole | 2001 |
Post-antifungal effect of polyene, azole and DNA-analogue agents against oral Candida albicans and Candida tropicalis isolates in HIV disease.
Topics: AIDS-Related Opportunistic Infections; Amphotericin B; Antifungal Agents; Candida; Candida albicans; Candidiasis, Oral; Fluconazole; Flucytosine; HIV Infections; Humans; Ketoconazole; Microbial Sensitivity Tests; Nystatin; Oropharynx; Pharyngeal Diseases; Statistics as Topic; Time Factors; Virulence | 2001 |
[Synthesis and antifungal activity of 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted-2-propanols].
Topics: Antifungal Agents; Candida albicans; Fluconazole; Ketoconazole; Microbial Sensitivity Tests; Microsporum; Saccharomyces; Structure-Activity Relationship; Triazoles | 1997 |
[In vitro antifungal susceptibility of dematiaceous filamentous fungi using the E-test].
Topics: Agar; Amphotericin B; Antifungal Agents; Colony Count, Microbial; Culture Media; Diffusion; Drug Resistance, Fungal; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mitosporic Fungi | 2001 |
Effects of azoles on human acute myelogenous leukemia blasts and T lymphocytes derived from acute leukemia patients with chemotherapy-induced cytopenia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antifungal Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Division; Clone Cells; Female; Fluconazole; Humans; Interferon-gamma; Interleukin-4; Itraconazole; Ketoconazole; Leukemia, Myeloid; Leukopenia; Lymphocyte Activation; Male; Miconazole; Middle Aged; Neoplastic Stem Cells; T-Lymphocytes | 2001 |
Drug susceptibility testing of Malassezia furfur strains to antifungal agents.
Topics: Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests | 2001 |
Multicenter Brazilian study of oral Candida species isolated from AIDS patients.
Topics: Adolescent; Adult; Aged; AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candidiasis, Oral; Drug Resistance, Fungal; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Serotyping | 2002 |
Post-antifungal effect and effects of sub-MIC concentrations on previously treated Candida spp.: influence of exposure time and concentration.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Candida glabrata; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Fluconazole; Ketoconazole; Microbial Sensitivity Tests; Time Factors | 2002 |
Use of the sensititre colorimetric microdilution panel for antifungal susceptibility testing of dermatophytes.
Topics: Amphotericin B; Antifungal Agents; Arthrodermataceae; Colorimetry; Coloring Agents; Dermatomycoses; Drug Resistance, Fungal; Epidermophyton; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Microsporum; Oxazines; Sensitivity and Specificity; Trichophyton; Xanthenes | 2002 |
[Identification and antifungal susceptibility of Candida spp isolated from invasive mycoses. Influence of growth inhibition percentage to determine minimal inhibitory concentration].
Topics: Adult; Amphotericin B; Antifungal Agents; Candida; Candidiasis; Child; Fluconazole; Growth Inhibitors; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 2002 |
Characterization of quinidine 3-hydroxylation as a probe for the CYP 3A enzyme using a novel capillary electrophoresis technique.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biomarkers; Cytochrome P-450 CYP3A; Electrophoresis, Capillary; Enzyme Inhibitors; Erythromycin; Fluconazole; Hydroxylation; Ketoconazole; Microsomes, Liver; Oxidoreductases, N-Demethylating; Quinidine; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism | 2002 |
Chromatographic determination of clotrimazole, ketoconazole and fluconazole in pharmaceutical formulations.
Topics: Antifungal Agents; Calibration; Capsules; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Clotrimazole; Densitometry; Fluconazole; Indicators and Reagents; Ketoconazole; Ointments; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2002 |
Prevalence and antifungal susceptibilities of yeast isolates during one year at a university hospital in Turkey.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Resistance, Multiple, Fungal; Fluconazole; Hospitals, University; Humans; Ketoconazole; Microbial Sensitivity Tests; Prevalence; Turkey | 2002 |
Variations in color.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Antifungal Agents; Black People; Diagnosis, Differential; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Selenium Compounds; Skin Pigmentation; Tinea Versicolor | 2003 |
In vitro susceptibilities of Malassezia species to a new triazole, albaconazole (UR-9825), and other antifungal compounds.
Topics: Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Flucytosine; In Vitro Techniques; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Pyrimidines; Quinazolines; Triazoles; Voriconazole | 2003 |
[Nosocomial urinary infection due to Trichosporon asahii. First two cases in Chile].
Topics: Amphotericin B; Antifungal Agents; Chile; Communicable Diseases, Emerging; Cross Infection; Drug Resistance, Fungal; Fatal Outcome; Fluconazole; Humans; Immunocompromised Host; Intensive Care Units; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Multiple Myeloma; Mycoses; Opportunistic Infections; Parkinson Disease; Postoperative Complications; Trichosporon; Urinary Catheterization; Urinary Tract Infections; Ventriculoperitoneal Shunt | 2003 |
Modulatory effect of cAMP on fungal ergosterol level and inhibitory activity of azole drugs.
Topics: Amphotericin B; Antifungal Agents; Atropine; Bucladesine; Candida albicans; Chromatography, Gas; Cryptococcus neoformans; Cyclic AMP; Drug Synergism; Ergosterol; Fluconazole; Ketoconazole; Microbial Sensitivity Tests; Phosphodiesterase Inhibitors | 2003 |
Fungal infection of sutureless self-sealing incision for cataract surgery.
Topics: Aged; Aged, 80 and over; Amphotericin B; Aspergillosis; Candidiasis; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Fungal; Female; Fluconazole; Humans; Ketoconazole; Male; Minimally Invasive Surgical Procedures; Natamycin; Phacoemulsification; Retrospective Studies; Scleritis; Surgical Wound Infection; Suture Techniques | 2003 |
Fungal peritonitis in 15 patients on continuous ambulatory peritoneal dialysis (CAPD).
Topics: Acremonium; Aged; Antifungal Agents; Aspergillus; Candida; Child; Drug Resistance, Fungal; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Kidney Failure, Chronic; Male; Mexico; Microbial Sensitivity Tests; Middle Aged; Mycoses; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis | 2003 |
Experimental evaluation of antifungal and antiseptic agents against Rhodotorula spp.
Topics: Amphotericin B; Anti-Infective Agents, Local; Antifungal Agents; Drug Resistance, Fungal; Econazole; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Nystatin; Rhodotorula | 2003 |
Effect of antifungal drugs on pathogenic Naegleria spp isolated from natural water sources.
Topics: Amphotericin B; Animals; Antifungal Agents; Fluconazole; Ketoconazole; Naegleria; Water Microbiology | 2003 |
[Modern antimycotics. What the treating physician needs to know].
Topics: Antifungal Agents; Arthrodermataceae; Child; Dermatomycoses; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Onychomycosis; Terbinafine; Time Factors | 2004 |
Prevalence of Candida dubliniensis among germ tube-positive yeasts recovered from the respiratory specimens in HIV-negative patients.
Topics: Adult; Aged; Amphotericin B; Candida; Drug Resistance, Fungal; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Mycological Typing Techniques; Respiratory System; Saudi Arabia; Serotyping | 2004 |
Antifungal susceptibility of 50 Candida isolates from invasive mycoses in Chile.
Topics: Amphotericin B; Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candidiasis; Chile; Critical Care; Drug Resistance, Fungal; Fluconazole; Humans; Inpatients; Intensive Care Units; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 2004 |
In vitro susceptibility of Candida species isolated from cancer patients to some antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Candida; Disease Susceptibility; Fluconazole; Flucytosine; Humans; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Neoplasms; Oropharynx | 2004 |
CaNdt80 is involved in drug resistance in Candida albicans by regulating CDR1.
Topics: Base Sequence; Candida albicans; Cloning, Molecular; Culture Media; DNA-Binding Proteins; DNA, Fungal; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Ketoconazole; Lac Operon; Membrane Transport Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factors | 2004 |
Etest for assessing the susceptibility of filamentous fungi.
Topics: Antifungal Agents; Culture Media; Fluconazole; Fungi; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Mycoses; Quality Control; Reproducibility of Results | 2004 |
In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis.
Topics: Antifungal Agents; Arthrodermataceae; Ascomycota; Clotrimazole; Econazole; Fluconazole; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Naphthalenes; Terbinafine; Thiophenes | 2004 |
[Prophylaxis of fungal infection in patients with hematologic neoplasms and severe neutropenia after high-dose chemotherapy].
Topics: Administration, Oral; Adolescent; Adult; Antifungal Agents; Antineoplastic Agents; Fluconazole; Hematologic Neoplasms; Humans; Itraconazole; Ketoconazole; Middle Aged; Mycoses; Neutropenia; Randomized Controlled Trials as Topic; Retrospective Studies | 2004 |
Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T. mentagrophytes by using a microdilution assay.
Topics: Antifungal Agents; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Propolis; Terbinafine; Trichophyton; Turkey | 2005 |
Slime production and proteinase activity of Candida species isolated from blood samples and the comparison of these activities with minimum inhibitory concentration values of antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Biofilms; Candida; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Peptide Hydrolases | 2005 |
Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Child; Drug Therapy, Combination; Eye Infections, Fungal; Female; Fluconazole; Fungi; Humans; Keratitis; Ketoconazole; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Treatment Outcome | 2006 |
DNA fingerprinting pattern and susceptibility to antifungal drugs in Cryptococcus neoformans variety grubii isolates from Barcelona city and rural environmental samples.
Topics: Amphotericin B; Antifungal Agents; Cryptococcus neoformans; DNA Fingerprinting; DNA, Fungal; Drug Resistance, Fungal; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Soil Microbiology; Spain; Triazoles; Voriconazole | 2005 |
In vitro susceptibility of oral Candida to seven antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Candida; Candida albicans; Candida glabrata; Candida tropicalis; Candidiasis, Oral; Drug Resistance, Fungal; Fluconazole; Humans; Itraconazole; Ketoconazole; Miconazole; Mouth Diseases; Nystatin; Pyrimidines; Triazoles; Voriconazole | 2005 |
Long term control of hypercortisolism with fluconazole: case report and in vitro studies.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aged, 80 and over; Antifungal Agents; Cell Line, Tumor; Corticosterone; Cushing Syndrome; Female; Fluconazole; Humans; Ketoconazole; Lung Neoplasms; Recurrence | 2006 |
Aureobasidium pullulans keratitis.
Topics: Ascomycota; Corneal Ulcer; Eye Infections, Fungal; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Middle Aged; Mycoses; Retrospective Studies | 2006 |
In vitro susceptibilities of Malaysian clinical isolates of Cryptococcus neoformans var. grubii and Cryptococcus gattii to five antifungal drugs.
Topics: Amphotericin B; Antifungal Agents; Cryptococcus; Cryptococcus neoformans; Drug Resistance, Fungal; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests | 2006 |
Antifungal susceptibilities of the species of the Pseudallescheria boydii complex.
Topics: Amphotericin B; Antifungal Agents; Candida; Drug Resistance, Fungal; Echinocandins; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Lipopeptides; Lipoproteins; Micafungin; Microbial Sensitivity Tests; Naphthalenes; Peptides, Cyclic; Pseudallescheria; Pyrimidines; Quality Control; Quinazolines; Scedosporium; Terbinafine; Thiazoles; Triazoles; Voriconazole | 2006 |
In vitro methods for antifungal susceptibility testing of Trichophyton spp.
Topics: Antifungal Agents; Fluconazole; Griseofulvin; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Naphthalenes; Terbinafine; Trichophyton | 2006 |
White piedra in children.
Topics: Administration, Oral; Adolescent; Antifungal Agents; Child; Child, Preschool; Connecticut; Diagnosis, Differential; Female; Fluconazole; Hair; Hair Preparations; Humans; Ketoconazole; Lice Infestations; Male; Mexico; New York City; Piedra; Trichosporon; United Kingdom; Yemen | 2006 |
In-vitro susceptibility testing by agar dilution method to determine the minimum inhibitory concentrations of amphotericin B, fluconazole and ketoconazole against ocular fungal isolates.
Topics: Amphotericin B; Antifungal Agents; Aspergillus; Candida; Drug Resistance, Fungal; Eye Diseases; Fluconazole; Keratitis; Ketoconazole; Microbial Sensitivity Tests; Mitosporic Fungi; Mycoses | 2006 |
Antifungal activities of azole agents against the Malassezia species.
Topics: Antifungal Agents; Azoles; Fluconazole; Humans; In Vitro Techniques; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Pyrimidines; Tinea Versicolor; Triazoles; Voriconazole | 2007 |
Induction of cytochrome P450 1A1 by ketoconazole and itraconazole but not fluconazole in murine and human hepatoma cell lines.
Topics: Animals; Antifungal Agents; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Fluconazole; Genes, Reporter; Humans; Itraconazole; Ketoconazole; Liver Neoplasms; Luciferases; Mice; Promoter Regions, Genetic; Receptors, Aryl Hydrocarbon; RNA, Messenger; Time Factors; Transcription, Genetic | 2007 |
Antifungal susceptibility testing of Trichophyton rubrum by E-test.
Topics: Antifungal Agents; Cells, Cultured; Drug Resistance, Fungal; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Tinea; Triazoles; Trichophyton; Voriconazole | 2007 |
[Oral isolates of Saccharomyces in patients with oral fungal infection and their susceptibility to antifungal drugs].
Topics: Antifungal Agents; Candida albicans; Candidiasis, Oral; Fluconazole; Humans; Ketoconazole; Nystatin; Saccharomyces | 2007 |
Interactions of azole antifungal agents with the human breast cancer resistance protein (BCRP).
Topics: Antifungal Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line; Cell Survival; Chlorophyll; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Flow Cytometry; Fluconazole; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Itraconazole; Ketoconazole; Neoplasm Proteins; Pyrimidines; Topotecan; Transfection; Triazoles; Voriconazole | 2007 |
Identification and in vitro antifungal susceptibility testing of 200 clinical isolates of Candida spp. responsible for fingernail infections.
Topics: Antifungal Agents; Brazil; Candida; Candidiasis; Ciclopirox; Fluconazole; Hand Dermatoses; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Naphthalenes; Onychomycosis; Pyridones; Terbinafine | 2007 |
Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination.
Topics: Animals; Catalysis; Cells, Cultured; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextromethorphan; Enzyme Inhibitors; Fluconazole; Fluoxetine; Fluvoxamine; Hepatocytes; Ketoconazole; Kinetics; Male; Miconazole; Microsomes, Liver; Midazolam; Phenytoin; Quinine; Rats; Rats, Sprague-Dawley; Tolbutamide | 2007 |
Induction of the NAD(P)H:quinone oxidoreductase 1 by ketoconazole and itraconazole: a mechanism of cancer chemoprotection.
Topics: Animals; Antifungal Agents; Carcinoma, Hepatocellular; Enzyme Activation; Enzyme Induction; Fluconazole; Itraconazole; Ketoconazole; Liver Neoplasms, Experimental; Mice; NAD; NAD(P)H Dehydrogenase (Quinone); Receptors, Aryl Hydrocarbon; RNA, Messenger; Time Factors; Transcription, Genetic; Tumor Cells, Cultured | 2007 |
Activity of caspofungin and voriconazole against clinical isolates of Candida and other medically important yeasts by the CLSI M-44A disk diffusion method with Neo-Sensitabs tablets.
Topics: Amphotericin B; Antifungal Agents; Candida; Caspofungin; Cryptococcus; Disk Diffusion Antimicrobial Tests; Drug Resistance, Fungal; Echinocandins; Fluconazole; Itraconazole; Ketoconazole; Lipopeptides; Pyrimidines; Rhodotorula; Triazoles; Trichosporon; Voriconazole | 2008 |
[Resistance to azolic compounds in clinical Trichophyton spp. strains].
Topics: Adult; Antifungal Agents; Cross Infection; Drug Resistance, Fungal; Drug Resistance, Multiple, Fungal; Epidermophyton; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Mexico; Microsporum; Onychomycosis; Tinea; Tinea Capitis; Tinea Pedis; Trichophyton | 2007 |
Quantitative correlations among CYP3A sensitive substrates and inhibitors: literature analysis.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Databases, Factual; Drug Interactions; Enzyme Inhibitors; Erythromycin; Fluconazole; Ketoconazole; Midazolam; Substrate Specificity; Verapamil | 2007 |
[Relative bioavailability and bioequivalence of the antimycotics ketoconazole and fluconazole].
Topics: Animals; Antifungal Agents; Biological Availability; Fluconazole; Humans; Ketoconazole; Male; Rabbits; Therapeutic Equivalency | 2006 |
Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone.
Topics: Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fluconazole; Humans; Hydroxylation; Ketoconazole; Lynestrenol; Microsomes, Liver; Norethindrone; Sulfaphenazole | 2008 |
Widespread, chronic, and fluconazole-resistant Trichophyton rubrum infection in an immunocompetent patient.
Topics: Animals; Antifungal Agents; Drug Resistance, Fungal; Female; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Middle Aged; Thiophenes; Tinea; Trichophyton | 2008 |
Effect of commonly used herbicides on the virulence factor CDR1 in Candida albicans.
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Fluconazole; Fungal Proteins; Ketoconazole; Membrane Transport Proteins | 2008 |
Chemosensitization prevents tolerance of Aspergillus fumigatus to antimycotic drugs.
Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus fumigatus; Benzaldehydes; Catechols; Cell Membrane; Cell Wall; Drug Resistance, Fungal; Fluconazole; Gene Deletion; Humans; Ketoconazole; Microbial Sensitivity Tests; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Oxidative Stress; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sorbitol; Thymol | 2008 |
Significance of isolation and drug susceptibility testing of non-Candida albicans species causing oropharyngeal candidiasis in HIV patients.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Candida; Candidiasis, Oral; Drug Resistance, Fungal; Fluconazole; HIV Infections; Humans; Ketoconazole; Microbial Sensitivity Tests | 2008 |
Reduction of fluconazole susceptibility of Candida albicans in APECED patients due to long-term use of ketoconazole and miconazole.
Topics: Antifungal Agents; Candida albicans; Drug Administration Schedule; Drug Resistance, Fungal; Fluconazole; Humans; Ketoconazole; Miconazole; Polyendocrinopathies, Autoimmune | 2008 |
Comparison of the anti-inflammatory activities of imidazole antimycotics in relation to molecular structure.
Topics: Anti-Inflammatory Agents; Antifungal Agents; Cells, Cultured; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Leukotriene B4; Molecular Structure; Neutrophils; Platelet Activating Factor; Pyrimidines; Triazoles; Voriconazole | 2008 |
Fungistatic effects of optical brightener 220 against Trichophyton tonsurans, Aspergillus fumigatus and Candida albicans.
Topics: Antifungal Agents; Aspergillus fumigatus; Candida albicans; Cells, Cultured; Culture Media; Fibroblasts; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Risk Factors; Sensitivity and Specificity; Stilbenes; Trichophyton | 2009 |
Susceptibility to voriconazole, fluconazole, and ketoconazole of yeast isolated from patients with hematological malignancies.
Topics: Antifungal Agents; Candida; Candidiasis; Drug Resistance, Fungal; Fluconazole; Hematologic Neoplasms; Humans; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 2008 |
Antifungal activities of natural and synthetic iron chelators alone and in combination with azole and polyene antibiotics against Aspergillus fumigatus.
Topics: Amphotericin B; Antifungal Agents; Aspergillus fumigatus; Ciclopirox; Deferiprone; Drug Combinations; Fluconazole; Iron Chelating Agents; Ketoconazole; Microbial Sensitivity Tests; Pyridones | 2009 |
The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Azides; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Membrane Transport Proteins; Miconazole; Mutagenesis, Site-Directed; Prazosin; Protein Transport; Rhodamines; Saccharomyces cerevisiae; Substrate Specificity | 2009 |
Growth inhibitory action of ebselen on fluconazole-resistant Candida albicans: role of the plasma membrane H+-ATPase.
Topics: Amphotericin B; Antifungal Agents; Azoles; Candida albicans; Cyclooxygenase Inhibitors; Cysteine; Drug Resistance, Fungal; Fluconazole; Isoindoles; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Organoselenium Compounds; Proton-Translocating ATPases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2009 |
Curcumin modulates efflux mediated by yeast ABC multidrug transporters and is synergistic with antifungals.
Topics: Anisomycin; Antifungal Agents; Biological Transport; Candida albicans; Curcumin; Cycloheximide; Drug Synergism; Enzyme Inhibitors; Fluconazole; Itraconazole; Ketoconazole; Methotrexate; Miconazole; Multidrug Resistance-Associated Proteins; Pyrimidines; Rhodamines; Saccharomyces cerevisiae; Triazoles; Voriconazole | 2009 |
In vitro synergistic effects of antituberculous drugs plus antifungals against Coccidioides posadasii.
Topics: Amphotericin B; Antifungal Agents; Antitubercular Agents; Caspofungin; Coccidioides; Coccidioidomycosis; Drug Synergism; Echinocandins; Ethambutol; Fluconazole; Humans; Isoniazid; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Pyrazinamide; Pyrimidines; Triazoles; Voriconazole | 2009 |
Direct antifungal susceptibility testing of positive Candida blood cultures by sensititre YeastOne.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Drug Resistance, Fungal; Fluconazole; Flucytosine; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyrimidines; Reagent Kits, Diagnostic; Sensitivity and Specificity; Time Factors; Triazoles; Voriconazole | 2009 |
Simultaneous determination of five systemic azoles in plasma by high-performance liquid chromatography with ultraviolet detection.
Topics: Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Fluconazole; Humans; Itraconazole; Ketoconazole; Pyrimidines; Quality Control; Reproducibility of Results; Spectrophotometry, Ultraviolet; Time Factors; Triazoles; Ultraviolet Rays; Voriconazole | 2009 |
In vitro investigation of antifungal activity of allicin alone and in combination with azoles against Candida species.
Topics: Antifungal Agents; Azoles; Candida; Candidiasis; Disulfides; Drug Synergism; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Sulfinic Acids | 2010 |
Screening of antimycotics in Swedish sewage treatment plants--waters and sludge.
Topics: Antifungal Agents; Clotrimazole; Econazole; Environmental Monitoring; Fluconazole; Ketoconazole; Miconazole; Naphthalenes; Sewage; Sweden; Terbinafine; Waste Disposal, Fluid; Water Pollutants, Chemical | 2010 |
Current concepts in systemic and topical therapy for superficial mycoses.
Topics: Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Antifungal Agents; Azoles; Dermatomycoses; Drug Administration Schedule; Drug Resistance, Fungal; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Morpholines; Tolnaftate; United States | 2010 |
Anticandidal effect of Ocimum sanctum essential oil and its synergy with fluconazole and ketoconazole.
Topics: Antifungal Agents; Candida; Drug Synergism; Erythrocytes; Fluconazole; Humans; Ketoconazole; Ocimum; Oils, Volatile; Plant Extracts | 2010 |
[Malassezia folliculitis: 21 cases].
Topics: Adolescent; Adult; Antifungal Agents; Dermatomycoses; Female; Fluconazole; Folliculitis; Humans; Ketoconazole; Kidney Transplantation; Malassezia; Male; Middle Aged; Postoperative Complications; Prospective Studies; Renal Dialysis; Risk Factors; Tunisia; Young Adult | 2010 |
In vitro-in vivo extrapolation predicts drug-drug interactions arising from inhibition of codeine glucuronidation by dextropropoxyphene, fluconazole, ketoconazole, and methadone in humans.
Topics: Analgesics, Opioid; Animals; Cattle; Codeine; Dextropropoxyphene; Drug Interactions; Fluconazole; Glucuronosyltransferase; Humans; In Vitro Techniques; Ketoconazole; Methadone; Microsomes, Liver; Models, Biological; Serum Albumin, Bovine | 2010 |
Azole binding properties of Candida albicans sterol 14-alpha demethylase (CaCYP51).
Topics: Antifungal Agents; Azoles; Candida albicans; Econazole; Fluconazole; Itraconazole; Ketoconazole; Miconazole; Protein Binding; Pyrimidines; Sterol 14-Demethylase; Triazoles; Voriconazole | 2010 |
Evaluation of the origin of a sample of Sporothrix schenckii that caused contamination of a researcher in Southern Brazil.
Topics: Brazil; Fluconazole; Humans; Ketoconazole; Laboratories; Male; Microbial Sensitivity Tests; Potassium Iodide; Random Amplified Polymorphic DNA Technique; Research Personnel; Sporothrix; Sporotrichosis | 2011 |
Ketoconazole and miconazole alter potassium homeostasis in Saccharomyces cerevisiae.
Topics: Antifungal Agents; Cations; Fluconazole; Glucose; Glucosephosphate Dehydrogenase; Homeostasis; Hydrogen-Ion Concentration; Itraconazole; Ketoconazole; Miconazole; Nucleotides; Oxygen Consumption; Potassium; Protons; Saccharomyces cerevisiae | 2011 |
In vitro susceptibility of fluconazole-susceptible and -resistant isolates of Malassezia pachydermatis against azoles.
Topics: Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 2011 |
Antifungal susceptibility and virulence attributes of bloodstream isolates of Candida from Hong Kong and Finland.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidemia; Caspofungin; Drug Resistance, Fungal; Echinocandins; Finland; Fluconazole; Flucytosine; Hemolysin Proteins; Hong Kong; Humans; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Peptide Hydrolases; Pyrimidines; Triazoles; Virulence Factors; Voriconazole | 2011 |
The quorum-sensing molecule farnesol is a modulator of drug efflux mediated by ABC multidrug transporters and synergizes with drugs in Candida albicans.
Topics: Amphotericin B; Antifungal Agents; Apoptosis; ATP-Binding Cassette Transporters; Biological Transport, Active; Candida albicans; Drug Resistance, Multiple, Fungal; Drug Synergism; Farnesol; Fluconazole; Fungal Proteins; Ketoconazole; Kinetics; Membrane Transport Proteins; Miconazole; Microbial Sensitivity Tests; Quorum Sensing; Reactive Oxygen Species; Rhodamines; Saccharomyces cerevisiae | 2011 |
Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiation.
Topics: Adult; Aged; Aged, 80 and over; Amphotericin B; Antifungal Agents; Candida; Candida albicans; Colony Count, Microbial; Dental Caries; Drug Resistance, Fungal; Female; Fluconazole; Head and Neck Neoplasms; Humans; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Mouth; Pyrimidines; Radiation Injuries; Saliva; Salivary Glands; Secretory Rate; Triazoles; Voriconazole; Xerostomia | 2012 |
In vitro antifungal susceptibility of Malassezia pachydermatis from dogs with and without skin lesions.
Topics: Animals; Antifungal Agents; Dermatomycoses; Dog Diseases; Dogs; Fluconazole; Itraconazole; Ketoconazole; Malassezia; Miconazole; Naphthalenes; Pyrimidines; Terbinafine; Triazoles; Voriconazole | 2012 |
Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.).
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diclofenac; Dioxoles; Ellipticines; Fish Proteins; Fluconazole; Hydroxylation; Ketoconazole; Kinetics; Lignans; Microsomes, Liver; Oxazines; Salmo salar; Sulfaphenazole; Tolbutamide | 2012 |
Distribution, behavior and fate of azole antifungals during mechanical, biological, and chemical treatments in sewage treatment plants in China.
Topics: Antifungal Agents; Azoles; Biodegradation, Environmental; China; Clotrimazole; Econazole; Environmental Monitoring; Fluconazole; Ketoconazole; Miconazole; Sewage; Waste Disposal, Fluid; Water Pollutants, Chemical | 2012 |
Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross-resistance to triazole antifungal agents.
Topics: Amphotericin B; Antifungal Agents; Candida glabrata; Caspofungin; Drug Resistance, Fungal; Echinocandins; Fluconazole; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 2012 |
CDR4 is the major contributor to azole resistance among four Pdr5p-like ABC transporters in Neurospora crassa.
Topics: Antifungal Agents; ATP-Binding Cassette Transporters; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Gene Knockout Techniques; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Neurospora crassa; Phylogeny; Sequence Homology, Amino Acid | 2012 |
Prototheca wickerhamii as a cause of neuroinfection in a child with congenital hydrocephalus. First case of human protothecosis in Poland.
Topics: Amphotericin B; Antifungal Agents; DNA, Plant; Fluconazole; Head; Humans; Hydrocephalus; Infant; Ketoconazole; Male; Meningoencephalitis; Microscopy, Electron; Molecular Sequence Data; Poland; Prototheca; Sequence Analysis, DNA; Tomography, X-Ray Computed; Treatment Outcome; Ventriculoperitoneal Shunt | 2012 |
Retigeric acid B enhances the efficacy of azoles combating the virulence and biofilm formation of Candida albicans.
Topics: Animals; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biofilms; Caco-2 Cells; Candida albicans; Candidiasis; Drug Synergism; Fluconazole; Fungal Proteins; Humans; Itraconazole; Ketoconazole; Male; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Triterpenes; Virulence | 2012 |
Fluconazole inhibits human adrenocortical steroidogenesis in vitro.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Cortodoxone; Desoxycorticosterone; Fluconazole; Humans; Hydrocortisone; Ketoconazole; Pregnenolone; Progesterone | 2012 |
Azole affinity of sterol 14α-demethylase (CYP51) enzymes from Candida albicans and Homo sapiens.
Topics: Antifungal Agents; Candida albicans; Clotrimazole; Escherichia coli; Fluconazole; Fungal Proteins; Humans; Itraconazole; Ketoconazole; Kinetics; Lanosterol; NADP; Protein Binding; Pyrimidines; Recombinant Proteins; Species Specificity; Sterol 14-Demethylase; Triazoles; Voriconazole | 2013 |
Hydroxyurea therapy in sickle cell anemia patients aids to maintain oral fungal colonization balance.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Antifungal Agents; Antisickling Agents; Candida; Candida glabrata; Candida tropicalis; Candidiasis, Oral; Case-Control Studies; Colony Count, Microbial; Cross-Sectional Studies; DMF Index; Drug Resistance, Fungal; Female; Fluconazole; Flucytosine; Humans; Hydroxyurea; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Mouth; Saliva; Secretory Rate; Young Adult | 2013 |
Differential pulse polarographic investigation of the antifungal drugs itraconazole, ketoconazole, fluconazole and voriconazole using a dropping mercury electrode.
Topics: Antifungal Agents; Electrochemistry; Electrodes; Fluconazole; Hydrogen-Ion Concentration; Indicators and Reagents; Itraconazole; Ketoconazole; Mercury; Polarography; Pyrimidines; Reference Standards; Reproducibility of Results; Triazoles; Voriconazole | 2012 |
Voriconazole suppresses the growth of Leishmania species in vitro.
Topics: Animals; Antiprotozoal Agents; Fluconazole; Inhibitory Concentration 50; Ketoconazole; Leishmania; Parasitic Sensitivity Tests; Pyrimidines; Species Specificity; Triazoles; Voriconazole | 2013 |
Pityriasis versicolor: a case of resistance to treatment.
Topics: Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Humans; Imidazoles; Itraconazole; Ketoconazole; Male; Middle Aged; Naphthalenes; Recurrence; Terbinafine; Tinea Versicolor; Treatment Failure | 2014 |
Transcription factor CCG-8 as a new regulator in the adaptation to antifungal azole stress.
Topics: Antifungal Agents; Down-Regulation; Drug Resistance, Fungal; Fluconazole; Fusarium; Gene Expression Regulation, Fungal; Genes, Fungal; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Neurospora crassa; Transcription Factors | 2014 |
Simultaneous and comprehensive in vivo analysis of cytochrome P450 activity by using a cocktail approach in rats.
Topics: Animals; Caffeine; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dextromethorphan; Drug Interactions; Fluconazole; Fluvoxamine; Ketoconazole; Losartan; Male; Midazolam; Omeprazole; Rats, Sprague-Dawley | 2014 |
Post-antifungal effect and adhesion to buccal epithelial cells of oral Candida dubliniensis isolates subsequent to limited exposure to amphotericin B, ketoconazole and fluconazole.
Topics: Amphotericin B; Antifungal Agents; Candida; Cells, Cultured; Epithelial Cells; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Mouth Mucosa; Mycology; Nephelometry and Turbidimetry | 2015 |
Effects of rifampin and ketoconazole on pharmacokinetics of morinidazole in healthy chinese subjects.
Topics: Animals; Antifungal Agents; Candida glabrata; Candidiasis; Cell Line; Female; Fluconazole; Fungal Proteins; Humans; Immunoblotting; Ketoconazole; Lectins; Membrane Transport Proteins; Mice; Mice, Inbred BALB C; Nitroimidazoles; Open Reading Frames; Rifampin | 2014 |
Impact of brief and sequential exposure to nystatin, amphotericin B, ketoconazole, and fluconazole in modulating adhesion traits of oral Candida dubliniensis isolates.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis; Epithelial Cells; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Mouth Mucosa; Nystatin | 2016 |
Genotypic, phenotypic, and proteomic characterization of Candida glabrata during sequential fluconazole exposure.
Topics: Antifungal Agents; Candida glabrata; Chromosomes, Fungal; Copper Sulfate; Culture Media; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Genotype; Hemolysin Proteins; Humans; Itraconazole; Ketoconazole; Metallothionein; Phenotype; Proteome; Virulence; Voriconazole | 2011 |
In vitro anti-yeast activity of chloramphenicol: A preliminary report.
Topics: Antifungal Agents; Candida; Caspofungin; Chloramphenicol; Cryptococcus neoformans; Echinocandins; Fluconazole; Humans; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Pilot Projects; Saccharomyces cerevisiae | 2015 |
Arteether resistance reversal by ketoconazole/fluconazole in rodent malaria parasite Plasmodium vinckei.
Topics: Animals; Antifungal Agents; Antimalarials; Artemisinins; Drug Resistance; Drug Therapy, Combination; Fluconazole; Ketoconazole; Malaria; Mice; Plasmodium | 2015 |
Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib.
Topics: Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Drug Interactions; Erythromycin; Fasting; Fluconazole; Humans; Ketoconazole; Models, Biological; Nitriles; Prospective Studies; Pyrazoles; Pyrimidines; Retrospective Studies; Rifampin | 2015 |
Cranial vena cava syndrome secondary to cryptococcal mediastinal granuloma in a cat.
Topics: Animals; Antifungal Agents; Antihypertensive Agents; Cat Diseases; Cats; Chylothorax; Cryptococcosis; Enalapril; Fluconazole; Granuloma; Ketoconazole; Male; Rutin; Superior Vena Cava Syndrome; Vena Cava, Superior | 2015 |
Antifungal susceptibility and phenotypic characterization of oral isolates of a black fungus from a nasopharyngeal carcinoma patient under radiotherapy.
Topics: Amphotericin B; Antifungal Agents; Biofilms; Carcinoma; Caspofungin; Chemoradiotherapy; Chemotherapy, Adjuvant; Drug Resistance, Fungal; Echinocandins; Exophiala; Fluconazole; Humans; Immunocompromised Host; Itraconazole; Ketoconazole; Lipopeptides; Male; Middle Aged; Mouth Diseases; Nasopharyngeal Neoplasms; Neoplasm Recurrence, Local; Opportunistic Infections; Phaeohyphomycosis; Radiotherapy, Intensity-Modulated; Voriconazole | 2015 |
Impact of short-term exposure of antifungal agents on hemolysin activity of oral Candida dubliniensis isolates from Kuwait and Sri Lanka.
Topics: Amphotericin B; Antifungal Agents; Candida; Candidiasis, Oral; Caspofungin; Chlorhexidine; Echinocandins; Fluconazole; Hemolysin Proteins; Humans; Ketoconazole; Kuwait; Lipopeptides; Microbial Sensitivity Tests; Nystatin; Sri Lanka; Time Factors | 2016 |
Effects of the association of antifungal drugs on the antimicrobial action of endodontic sealers.
Topics: Antifungal Agents; Bismuth; Calcium Hydroxide; Candida albicans; Epoxy Resins; Fluconazole; Ketoconazole; Microbial Sensitivity Tests; Reproducibility of Results; Root Canal Filling Materials; Salicylates; Statistics, Nonparametric | 2015 |
In vitro activities of a wide panel of antifungal drugs against various Scopulariopsis and Microascus species.
Topics: Amphotericin B; Antifungal Agents; Ascomycota; Caspofungin; Drug Resistance, Fungal; Echinocandins; Fluconazole; Flucytosine; Itraconazole; Ketoconazole; Lipopeptides; Microbial Sensitivity Tests; Scopulariopsis; Triazoles; Voriconazole | 2015 |
Transcription factor ADS-4 regulates adaptive responses and resistance to antifungal azole stress.
Topics: Antifungal Agents; Azoles; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Neurospora crassa | 2015 |
Vba4p, a vacuolar membrane protein, is involved in the drug resistance and vacuolar morphology of Saccharomyces cerevisiae.
Topics: Amino Acid Transport Systems, Basic; Amino Acids; Antifungal Agents; Biological Transport; Drug Resistance, Fungal; Fluconazole; Gene Expression; Intracellular Membranes; Ketoconazole; Miconazole; Organelle Shape; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Saccharomyces cerevisiae; Salt Tolerance; Sodium Chloride; Vacuoles | 2016 |
Synthetic antimicrobial β-peptide in dual-treatment with fluconazole or ketoconazole enhances the in vitro inhibition of planktonic and biofilm Candida albicans.
Topics: Antifungal Agents; Antimicrobial Cationic Peptides; Biofilms; Candida albicans; Cell Proliferation; Cell Survival; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Hep G2 Cells; Humans; In Vitro Techniques; Ketoconazole; Plankton | 2015 |
Phytotoxicity of wastewater-born micropollutants--Characterisation of three antimycotics and a cationic surfactant.
Topics: Agriculture; Antifungal Agents; Fertilizers; Fluconazole; Imidazoles; Ketoconazole; Plants; Sewage; Soil; Soil Pollutants; Surface-Active Agents; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2016 |
Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.
Topics: Animals; Antifungal Agents; Binding Sites; Candida glabrata; Candidiasis; DNA-Binding Proteins; Drug Resistance, Fungal; Drug Resistance, Multiple, Fungal; Fluconazole; Fungal Proteins; Gene Expression Regulation, Fungal; Hydrazines; Ketoconazole; Mediator Complex; Mice; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae Proteins; Thiourea; Trans-Activators; Transcription Factors; Transcriptional Activation; Up-Regulation | 2016 |
Exploratory Investigation of the Limiting Steps of Oral Absorption of Fluconazole and Ketoconazole in Children Using an In Silico Pediatric Absorption Model.
Topics: Adult; Antifungal Agents; Biopharmaceutics; Child; Computer Simulation; Dose-Response Relationship, Drug; Fluconazole; Humans; Ketoconazole; Models, Biological; Mouth Mucosa; Permeability; Solubility | 2016 |
Molecular typing of environmental Cryptococcus neoformans/C. gattii species complex isolates from Manaus, Amazonas, Brazil.
Topics: Amphotericin B; Animals; Antifungal Agents; Birds; Brazil; Cryptococcosis; Cryptococcus gattii; Cryptococcus neoformans; Disease Reservoirs; Environmental Microbiology; Feces; Fluconazole; Humans; Itraconazole; Ketoconazole; Molecular Typing; Mycological Typing Techniques; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Trees | 2016 |
The Investigational Drug VT-1129 Is a Highly Potent Inhibitor of Cryptococcus Species CYP51 but Only Weakly Inhibits the Human Enzyme.
Topics: Antifungal Agents; Clotrimazole; Cryptococcus; Enzyme Activation; Ergosterol; Fluconazole; Humans; Itraconazole; Ketoconazole; Lanosterol; Pyridines; Sterol 14-Demethylase; Tetrazoles; Voriconazole | 2016 |
Azole Antifungal Sensitivity of Sterol 14α-Demethylase (CYP51) and CYP5218 from Malassezia globosa.
Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Cytochrome P450 Family 51; Drug Evaluation, Preclinical; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Kinetics; Lipids; Malassezia; Spectrophotometry; Sterol 14-Demethylase; Sterols; Voriconazole | 2016 |
Unbound liver concentration is the true inhibitor concentration that determines cytochrome P450-mediated drug-drug interactions in rat liver.
Topics: Animals; Area Under Curve; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fluconazole; Ketoconazole; Kinetics; Liver; Microsomes, Liver; Rats | 2017 |
Investigation of the antifungal potential of linalool against clinical isolates of fluconazole resistant Trichophyton rubrum.
Topics: Acyclic Monoterpenes; Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Monoterpenes; Mycelium; Spores, Fungal; Terpenes; Tinea; Trichophyton | 2017 |
The Tetrazole VT-1161 Is a Potent Inhibitor of Trichophyton rubrum through Its Inhibition of T. rubrum CYP51.
Topics: Antifungal Agents; Azoles; Candida albicans; Clotrimazole; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Pyridines; Sterol 14-Demethylase; Substrate Specificity; Tetrazoles; Trichophyton; Voriconazole | 2017 |
Candidiasis: Prevalence and resistance profiling in a tertiary care hospital of Pakistan.
Topics: Amphotericin B; Antifungal Agents; Candida albicans; Candida glabrata; Candidiasis; Cross-Sectional Studies; Drug Resistance, Fungal; Fluconazole; Humans; Ketoconazole; Kidney Failure, Chronic; Kidney Transplantation; Microbial Sensitivity Tests; Pakistan; Prevalence; Prospective Studies; Tertiary Care Centers; Voriconazole | 2017 |
Effects of (1
Topics: Chagas Disease; Drug Combinations; Drug Synergism; Fluconazole; Humans; Ketoconazole; Nitroimidazoles; Pentanones; Trypanosoma cruzi | 2017 |
Quantitative prediction of the extent of drug-drug interaction using a physiologically based pharmacokinetic model that includes inhibition of drug metabolism determined in cryopreserved hepatocytes.
Topics: Animals; Cryopreservation; Drug Interactions; Fluconazole; Hepatocytes; Ketoconazole; Microsomes, Liver; Nifedipine; Rats | 2018 |
Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software.
Topics: Ciprofloxacin; Clarithromycin; Computer Simulation; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Fluconazole; Humans; Itraconazole; Ketoconazole; Models, Biological; Paroxetine; Quinidine; Rifampin; Software | 2018 |
Pityrosporum folliculitis: A retrospective review of 110 cases.
Topics: Acne Vulgaris; Adolescent; Anti-Bacterial Agents; Antifungal Agents; Child; Facial Dermatoses; Female; Fluconazole; Folliculitis; Forehead; Humans; Ketoconazole; Malassezia; Male; Pruritus; Retrospective Studies; Torso; Young Adult | 2018 |
Multi-azole-resistant strain of Malassezia pachydermatis isolated from a canine Malassezia dermatitis.
Topics: Animals; Antifungal Agents; Azoles; Cytochrome P-450 Enzyme System; Dermatitis; Dermatomycoses; Dog Diseases; Dogs; Drug Resistance, Multiple, Fungal; Drug Synergism; Fluconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Mutation, Missense; Open Reading Frames; Voriconazole | 2019 |
Malassezia pachydermatis from animals: Planktonic and biofilm antifungal susceptibility and its virulence arsenal.
Topics: Animals; Antifungal Agents; Bacterial Adhesion; Biofilms; Caenorhabditis elegans; Cat Diseases; Cats; Dermatomycoses; Dog Diseases; Dogs; Epithelial Cells; Fluconazole; Foxes; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Peptide Hydrolases; Phospholipases; Virulence | 2018 |
Antifungal susceptibility of yeasts isolated from anthropogenic watershed.
Topics: Amphotericin B; Antifungal Agents; Drug Resistance, Fungal; Fluconazole; Fresh Water; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Reference Values; Sequence Analysis, DNA; Voriconazole; Yeasts | 2019 |
Comparison of the inhibitory effect of ketoconazole, voriconazole, fluconazole, and itraconazole on the pharmacokinetics of bosentan and its corresponding active metabolite hydroxy bosentan in rats.
Topics: Animals; Antifungal Agents; Antihypertensive Agents; Bosentan; Drug Interactions; Fluconazole; Itraconazole; Ketoconazole; Male; Rats; Rats, Sprague-Dawley; Triazoles; Voriconazole | 2020 |
The classic azole antifungal drugs are highly potent endocrine disruptors in vitro inhibiting steroidogenic CYP enzymes at concentrations lower than therapeutic Cmax.
Topics: Antifungal Agents; Aromatase; Aromatase Inhibitors; Cell Line, Tumor; Clotrimazole; Dose-Response Relationship, Drug; Endocrine Disruptors; Fluconazole; Gas Chromatography-Mass Spectrometry; Humans; Inhibitory Concentration 50; Ketoconazole; Miconazole; Steroid 17-alpha-Hydroxylase | 2019 |
Evaluation of the Antifungal Activity of
Topics: Animals; Antifungal Agents; Arthrodermataceae; Azoles; Candida; Cryptococcus; Drug Combinations; Drug Synergism; Fluconazole; Guidelines as Topic; Humans; Itraconazole; Ketoconazole; Mentha piperita; Microbial Sensitivity Tests; Monoterpenes; Oils, Volatile | 2019 |
Identification and Antifungal Activity Profile of Candida Species Isolated from Patients with Pemphigus Vulgaris with Oral Lesions.
Topics: Adult; Amphotericin B; Antifungal Agents; Candida; Candidiasis, Oral; Disk Diffusion Antimicrobial Tests; Econazole; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Pemphigus; Triazoles | 2019 |
In vitro antifungal activity of luliconazole against nondermatophytic moulds.
Topics: Amphotericin B; Antifungal Agents; Clotrimazole; Fluconazole; Fungi; Humans; Imidazoles; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Morpholines; Sequence Analysis, DNA; Terbinafine; Triazoles; Voriconazole | 2020 |
The Influence of Different Triazole Antifungal Agents on the Pharmacokinetics of Cyclophosphamide.
Topics: Antifungal Agents; Cyclophosphamide; Drug Interactions; Fluconazole; Humans; Itraconazole; Ketoconazole; Models, Biological | 2020 |
Comparison of in vitro antifungal activity of novel triazoles with available antifungal agents against dermatophyte species caused tinea pedis.
Topics: Antifungal Agents; Arthrodermataceae; Dermatomycoses; Fluconazole; Griseofulvin; Humans; Imidazoles; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Terbinafine; Tinea; Tinea Pedis; Triazoles; Trichophyton; Voriconazole | 2020 |
Comparative evaluation of E-test and CLSI methods for Itraconazole, Fluconazole and Ketoconazole susceptibilities of Microsporum canis strains.
Topics: Animals; Antifungal Agents; Cats; Dogs; Fluconazole; Indicator Dilution Techniques; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Microsporum | 2020 |
Marked virulence and azole resistance in Candida albicans isolated from patients with periodontal disease.
Topics: A549 Cells; Antifungal Agents; Azoles; Candida albicans; Drug Resistance, Fungal; Fluconazole; Fungal Proteins; Humans; Ketoconazole; Microbial Sensitivity Tests; Periodontal Diseases; Virulence | 2020 |
Physiologically based pharmacokinetic modeling and simulation to predict drug-drug interactions of ivosidenib with CYP3A perpetrators in patients with acute myeloid leukemia.
Topics: Administration, Oral; Antineoplastic Agents; Area Under Curve; Computer Simulation; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Fluconazole; Glycine; Healthy Volunteers; Humans; Itraconazole; Ketoconazole; Leukemia, Myeloid, Acute; Male; Microsomes, Liver; Models, Biological; Pyridines; Rifampin | 2020 |
High frequency of azole resistant Candida spp. colonization among presumptive multidrug resistant tuberculosis (MDR-TB) patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antifungal Agents; Antitubercular Agents; Candida; Candidiasis; Child; Drug Interactions; Drug Resistance, Multiple, Fungal; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Microbial Sensitivity Tests; Middle Aged; Rifampin; Species Specificity; Tuberculosis, Multidrug-Resistant; Young Adult | 2020 |
Effects of nanoplastic on toxicity of azole fungicides (ketoconazole and fluconazole) in zebrafish embryos.
Topics: Animals; Azoles; Embryo, Nonmammalian; Fluconazole; Fungicides, Industrial; Ketoconazole; Microplastics; Oxidative Stress; Water Pollutants, Chemical; Zebrafish | 2021 |
Activity of antifungal drugs and Brazilian red and green propolis extracted with different methodologies against oral isolates of Candida spp.
Topics: Antifungal Agents; Candidiasis, Oral; Fluconazole; Humans; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Plant Extracts; Propolis; Stomatitis, Denture | 2021 |
In vitro activity of 23 antifungal drugs against 54 clinical and environmental Aspergillus oryzae isolates.
Topics: Amphotericin B; Anidulafungin; Antifungal Agents; Aspergillus oryzae; Clotrimazole; Econazole; Fluconazole; Griseofulvin; Humans; Itraconazole; Ketoconazole; Miconazole; Microbial Sensitivity Tests; Natamycin; Nystatin; Terbinafine; Tolnaftate; Voriconazole | 2022 |
Malassezia species: the need to establish epidemiological cutoff values.
Topics: Amphotericin B; Animals; Antifungal Agents; Fluconazole; Humans; Itraconazole; Ketoconazole; Malassezia; Microbial Sensitivity Tests; Voriconazole | 2022 |
Feline sporotrichosis caused by Sporothrix schenckii sensu stricto in Southern Thailand: phenotypic characterization, molecular identification, and antifungal susceptibility.
Topics: Amphotericin B; Animals; Antifungal Agents; Calmodulin; Cat Diseases; Cats; Fluconazole; Itraconazole; Ketoconazole; Microbial Sensitivity Tests; Phylogeny; Sporothrix; Sporotrichosis; Thailand; Tubulin | 2022 |
Antifungal susceptibility profile of yeasts isolated from the oral cavity of cats.
Topics: Animals; Antifungal Agents; Candida; Cats; Fluconazole; Humans; Ketoconazole; Microbial Sensitivity Tests; Mouth; Yeasts | 2023 |
Sterol 14alpha-demethylase as a potential target for antitrypanosomal therapy: enzyme inhibition and parasite cell growth.
Topics: Animals; Antiprotozoal Agents; Cytochrome P-450 Enzyme Inhibitors; Oxidoreductases; Sterol 14-Demethylase; Substrate Specificity; Trypanosoma brucei brucei; Trypanosoma cruzi; Trypanosomiasis | 2007 |
Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen.
Topics: Cholesterol; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Host-Pathogen Interactions; Humans; Hydroxylation; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Structure, Tertiary | 2010 |
Synthesis, biological evaluation and quantitative structure-active relationships of 1,3-thiazolidin-4-one derivatives. A promising chemical scaffold endowed with high antifungal potency and low cytotoxicity.
Topics: Antifungal Agents; Candida; Carbon-13 Magnetic Resonance Spectroscopy; Drug Screening Assays, Antitumor; Gram-Negative Bacteria; Gram-Positive Bacteria; Hep G2 Cells; Humans; Microbial Sensitivity Tests; Proton Magnetic Resonance Spectroscopy; Quantitative Structure-Activity Relationship; Thiazolidines | 2017 |
Combating Drug-Resistant Fungi with Novel Imperfectly Amphipathic Palindromic Peptides.
Topics: Amino Acid Sequence; Animals; Antifungal Agents; Candida albicans; Cytoplasm; Drug Resistance, Fungal; HEK293 Cells; Hemolysis; Humans; Hydrophobic and Hydrophilic Interactions; Intracellular Membranes; Inverted Repeat Sequences; Mice; Models, Molecular; Peptides; Protein Conformation; RAW 264.7 Cells | 2018 |
Design, synthesis and evaluation of benzoheterocycle analogues as potent antifungal agents targeting CYP51.
Topics: Antifungal Agents; Aspergillus fumigatus; Binding Sites; Candida albicans; Catalytic Domain; Cryptococcus neoformans; Drug Design; Drug Resistance, Fungal; Drug Stability; Fluconazole; Fungal Proteins; Gas Chromatography-Mass Spectrometry; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Protein Isoforms; Sterol 14-Demethylase; Sterols; Structure-Activity Relationship; Triazoles | 2018 |
Design, synthesis and bio-evaluation of C-1 alkylated tetrahydro-β-carboline derivatives as novel antifungal lead compounds.
Topics: Alkylation; Amphotericin B; Antifungal Agents; Candida; Carbolines; Cell Survival; Cryptococcus neoformans; Drug Design; Drug Synergism; Fluconazole; HEK293 Cells; Humans; Kinetics; Microbial Sensitivity Tests; Structure-Activity Relationship | 2020 |
Design, synthesis and evaluation of hydrazine and acyl hydrazone derivatives of 5-pyrrolidin-2-one as antifungal agents.
Topics: Antifungal Agents; Drug Design; Fungi; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Pyrrolidinones; Structure-Activity Relationship | 2020 |
Improving the metabolic stability of antifungal compounds based on a scaffold hopping strategy: Design, synthesis, and structure-activity relationship studies of dihydrooxazole derivatives.
Topics: Antifungal Agents; Drug Design; Humans; Molecular Structure; Structure-Activity Relationship | 2021 |
Design, synthesis and evaluation of novel 5-phenylthiophene derivatives as potent fungicidal of Candida albicans and antifungal reagents of fluconazole-resistant fungi.
Topics: Antifungal Agents; Candida albicans; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Fungal; Fluconazole; Fungicides, Industrial; Humans; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Thiophenes | 2021 |
Relaxed Substrate Requirements of Sterol 14α-Demethylase from
Topics: 14-alpha Demethylase Inhibitors; Ligands; Naegleria fowleri; Sterol 14-Demethylase; Substrate Specificity | 2021 |
Novel Aryl Alkamidazole Derivatives as Multifunctional Antifungal Inhibitors: Design, Synthesis, and Biological Evaluation.
Topics: Antifungal Agents; Drug Design; Microbial Sensitivity Tests; Structure-Activity Relationship | 2022 |