fluconazole and fluorouracil

fluconazole has been researched along with fluorouracil in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.69)18.2507
2000's8 (30.77)29.6817
2010's13 (50.00)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Chapeland-Leclerc, F; Chastin, C; Florent, M; Gibot-Leclerc, S; Jean, D; Noël, T; Papon, N; Villard, J1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Kumar, P; Majeed, AB; Mani, V; Mishra, RK; Narasimhan, B; Ramasamy, K; Sharma, SK1
Hamid, A; Jaglan, S; Klapötke, TM; Kumar, D; Narasimhan, B; Qazi, AK; Singh, K; Stierstorfer, J; Verma, V1
El-Gohary, NS; Shaaban, MI3
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chanu, MB; Mahendra, M; Puttaraju, KB; Rai, K; Rasal, VP; Shivashankar, K; Venkata Vivek, PN1
Chen, PJ; Gu, YF; He, P; Jiang, TF; Liu, HM; Shao, KP; Xue, DQ; Yang, A; Zhang, QR; Zhang, XS1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Abdel-Rahman, SA; El-Ashry, SM; El-Bendary, ER; El-Gohary, NS; Shaaban, MI1
Dinh Thanh, N; Minh Tri, N; Ngoc Toan, V; Thi Thu Huong, N1
Han, H; Qi, XR; Shen, L; Tang, HF; Xu, QZ; Yang, WS; Yi, YH; Yuan, CH1
Koga, H; Kono, S1
Arranz-Caso, JA; García-Altozano, J; Gomez-Herruz, P; Lopez-Pizarro, VM; Martinez-Martinez, J1
Aboagye, EO; Price, PM; Saleem, A1
Nakanishi, T; Sekimizu, K1
Yamaguchi, H1
Bive, BZ; Bontems, S; Hayette, MP; Lelo, GM; Mudogo, CN; Sacheli, R; Zakayi, PK1

Reviews

3 review(s) available for fluconazole and fluorouracil

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
In vivo monitoring of drugs using radiotracer techniques.
    Advanced drug delivery reviews, 2000, Mar-15, Volume: 41, Issue:1

    Topics: Drug Administration Schedule; Drug Monitoring; Fluconazole; Fluorouracil; Humans; Models, Biological; Radionuclide Imaging; Receptors, Cell Surface; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon

2000
[Antifungal drug].
    Nihon rinsho. Japanese journal of clinical medicine, 2003, Volume: 61 Suppl 2

    Topics: Amphotericin B; Anti-Bacterial Agents; Antifungal Agents; Azoles; Caspofungin; Drug Design; Drug Resistance, Fungal; Echinocandins; Fluconazole; Fluorouracil; Fungi; Humans; Itraconazole; Lipopeptides; Lipoproteins; Micafungin; Mycoses; Opportunistic Infections; Peptides; Peptides, Cyclic; Polyenes; Pyrimidines

2003

Other Studies

23 other study(ies) available for fluconazole and fluorouracil

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Molecular mechanism of flucytosine resistance in Candida lusitaniae: contribution of the FCY2, FCY1, and FUR1 genes to 5-fluorouracil and fluconazole cross-resistance.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:1

    Topics: Alleles; Antifungal Agents; Candida; Cloning, Molecular; Cytosine Deaminase; DNA, Fungal; Drug Resistance, Fungal; Fluconazole; Flucytosine; Fluorouracil; Fungal Proteins; Genetic Complementation Test; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Pentosyltransferases; Plasmids; Sequence Analysis, DNA

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis, antimicrobial, anticancer evaluation and QSAR studies of 6-methyl-4-[1-(2-substituted-phenylamino-acetyl)-1H-indol-3-yl]-2-oxo/thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylic acid ethyl esters.
    European journal of medicinal chemistry, 2012, Volume: 48

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell Survival; HCT116 Cells; Humans; Indoles; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines; Quantitative Structure-Activity Relationship; Spectroscopy, Fourier Transform Infrared

2012
Synthesis, antimicrobial and cytotoxicity study of 1,3-disubstituted-1H-naphtho[1,2-e][1,3]oxazines.
    European journal of medicinal chemistry, 2012, Volume: 56

    Topics: Anti-Bacterial Agents; Antifungal Agents; Aspergillus niger; Candida albicans; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured

2012
Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of fused [1,3,4]thiadiazoles.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Artemia; Candida albicans; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Escherichia coli; HCT116 Cells; HL-60 Cells; HT29 Cells; Humans; K562 Cells; Lethal Dose 50; MCF-7 Cells; Microbial Sensitivity Tests; Models, Chemical; Molecular Structure; Quorum Sensing; Staphylococcus aureus; Structure-Activity Relationship; Thiadiazoles

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Microwave assisted synthesis of dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones; synthesis, in vitro antimicrobial and anticancer activities of novel coumarin substituted dihydrobenzo[4,5]imidazo[1,2-a]pyrimidin-4-ones.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Coumarins; Drug Screening Assays, Antitumor; Fungi; Humans; Microbial Sensitivity Tests; Microwaves; Models, Molecular; Molecular Structure; Pyrimidinones

2013
Synthesis, in vitro antimicrobial and cytotoxic activities of novel pyrimidine-benzimidazol combinations.
    Bioorganic & medicinal chemistry letters, 2014, Jun-15, Volume: 24, Issue:12

    Topics: Anti-Infective Agents; Bacteria; Benzimidazoles; Candida albicans; Cell Line, Tumor; Cell Survival; Combinatorial Chemistry Techniques; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure; Pyrimidines

2014
Synthesis and biological evaluation of a new series of benzimidazole derivatives as antimicrobial, antiquorum-sensing and antitumor agents.
    European journal of medicinal chemistry, 2017, May-05, Volume: 131

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fungi; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2017
Synthesis, antimicrobial, antiquorum-sensing and antitumor activities of new benzimidazole analogs.
    European journal of medicinal chemistry, 2017, Sep-08, Volume: 137

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Aspergillus fumigatus; Bacillus cereus; Benzimidazoles; Candida albicans; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Escherichia coli; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Quorum Sensing; Staphylococcus aureus; Structure-Activity Relationship

2017
Synthesis, antimicrobial, antiquorum-sensing, antitumor and cytotoxic activities of new series of cyclopenta(hepta)[b]thiophene and fused cyclohepta[b]thiophene analogs.
    European journal of medicinal chemistry, 2017, Nov-10, Volume: 140

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Bacteria; Cell Line; Cell Proliferation; Cycloheptanes; Cyclopentanes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fungi; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship; Thiophenes

2017
Synthesis and biological screening of thiosemicarbazones of substituted 3-acetylcoumarins having d-glucose moiety.
    Bioorganic & medicinal chemistry letters, 2020, 12-15, Volume: 30, Issue:24

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Bacteria; Bacterial Infections; Coumarins; Fungi; Glucose; Humans; Microbial Sensitivity Tests; Mycoses; Structure-Activity Relationship; Thiosemicarbazones

2020
A new sulfated triterpene glycoside from the sea cucumber Colochirus quadrangularis, and evaluation of its antifungal, antitumor and immunomodulatory activities.
    Bioorganic & medicinal chemistry, 2021, 07-01, Volume: 41

    Topics: Animals; Antifungal Agents; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Glycosides; Humans; Immunomodulation; Mice; Mice, Nude; Molecular Structure; Neoplasms, Experimental; Saponins; Sea Cucumbers; Triterpenes

2021
[Diagnosis and therapy of pulmonary mycoses].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1993, Sep-10, Volume: 82, Issue:9

    Topics: Adolescent; Adult; Aged; Amphotericin B; Cryptococcosis; Cryptococcus neoformans; Female; Fluconazole; Fluorouracil; Humans; Lung Diseases, Fungal; Male; Middle Aged; Serologic Tests

1993
Candida albicans osteomyelitis of the zygomatic bone. A distinctive case with a possible peculiar mechanism of infection and therapeutic failure with fluconazole.
    Diagnostic microbiology and infectious disease, 1996, Volume: 24, Issue:3

    Topics: Administration, Inhalation; Amphotericin B; Biopsy; Candidiasis; Candidiasis, Oral; Diabetes Complications; Fluconazole; Fluorouracil; Humans; Male; Middle Aged; Osteomyelitis; Steroids; Zygoma

1996
SDT1/SSM1, a multicopy suppressor of S-II null mutant, encodes a novel pyrimidine 5'-nucleotidase.
    The Journal of biological chemistry, 2002, Jun-14, Volume: 277, Issue:24

    Topics: 5'-Nucleotidase; Amphotericin B; Antifungal Agents; Dose-Response Relationship, Drug; Escherichia coli; Fluconazole; Flucytosine; Fluorouracil; Fungal Proteins; Molecular Sequence Data; Nucleotidases; Phosphorylation; Protein Binding; Recombinant Proteins; Ribosomal Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity

2002
Correlation of antifungal susceptibility and sequence types within Cryptococcus neoformans VNI from HIV patients, and ERG11 gene polymorphism.
    Journal de mycologie medicale, 2023, Volume: 33, Issue:4

    Topics: Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Democratic Republic of the Congo; Drug Resistance, Fungal; Fluconazole; Flucytosine; Fluorouracil; HIV Infections; Humans; Microbial Sensitivity Tests; Polymorphism, Genetic

2023