fluconazole and cyclosporine

fluconazole has been researched along with cyclosporine in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (20.97)	18.2507
2000's	25 (40.32)	29.6817
2010's	23 (37.10)	24.3611
2020's	1 (1.61)	2.80

Authors

Authors	Studies
Dantzig, AH; Ekins, S; Kim, RB; Lan, LB; Leake, BF; Schuetz, EG; Schuetz, JD; Shepard, RL; Wikel, JH; Winter, MA; Wrighton, SA; Yasuda, K	1
Furuya, K; Lan, LB; Sanglard, D; Schuetz, EG; Schuetz, JD; Yasuda, K	1
Chang, TK; Ensom, MH; Kiang, TK	1
Berdicevsky, I; Eads, E; Heitman, J; Horwitz, BA; Kaufman, G; Onyewu, C; Perfect, JR; Schell, WA; Ullmann, Y	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, X; Lin, X; Skolnik, S; Wang, J	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Adibzadeh, M; Friccius, H; Pawelec, G; Pohla, H; Schenk, A; Siegels-Hübenthal, P	1
Alpers, CE; Collins, BS; Davis, CL; Marsh, CL; McVicar, JP; Perkins, JD	1
Carey, D; Lee, HS; Tett, S	1
Back, DJ; Tjia, JF	1
Andreu, J; Campistol, JM; De la Torre, M; Oppenheimer, F; Ricart, MJ; Torregrosa, V; Vilardell, J	1
Bause, H; Höver, S; Scholz, J; Schulz, M; Steinfath, M	1
Barbara, JA; Clarkson, AR; LaBrooy, J; McNeil, JD; Woodroffe, AJ	1
López-Gil, JA	1
Dix, SP; Geller, RB; Lin, LS; Mullins, RE; Osowski, CL; Wingard, JR	1
Burke, MD; Hawksworth, GM; Humphrey, MJ; Omar, G; Whiting, PH	1
McLachlan, AJ; Tett, SE	1
Gupta, KL; Jha, V; Kohli, HS; Krishna, VS; Sakhuja, V; Singh, B; Sud, K; Thennarasu, K	1
Busuttil, RW; Pakrasi, A; Winston, DJ	1
Cardenas, ME; Cruz, MC; Del Poeta, M; Heitman, J; Movva, NR; Perfect, JR; Quesniaux, VF; Wang, P; Wenger, R; Zenke, G	1
Bille, J; Glauser, MP; Marchetti, O; Moreillon, P; Sanglard, D	1
Bille, J; Entenza, JM; Glauser, MP; Marchetti, O; Moreillon, P; Sanglard, D	1
Brink, NS; Goldstone, AH; Kottaridis, PD; Linch, DC; Mackinnon, S; McKeag, N; Peggs, KS; Preiser, W; Tedder, RS	1
Adamson, R; DiRenzo, T; Friedman, GS; Kaplan, B; Mathis, AS	1
Asaka, M; Chiba, K; Hashino, S; Izumiyama, K; Suzuki, S; Takahata, M	1
Blankenship, JR; Cardenas, ME; Cruz, MC; Davis, D; Del Poeta, M; Goldstein, AL; Heitman, J; McCusker, JH; Perfect, JR	1
Lee, CH; Tsai, TH; Yeh, PH	1
Bille, J; Entenza, JM; Glauser, MP; Marchetti, O; Moreillon, P; Sanglard, D; Vouillamoz, J	1
Ihm, CG; Kim, HJ; Kim, MJ; Lee, JH; Lee, MH; Lee, TW; Lee, YA	1
Cox, GM; Ganous, TM; Kingsbury, JM; McCusker, JH; Pascon, RC	1
Cappello, D; Di Mare, M; Fiamingo, P; Gagliano, M; Giuffrida, G; Macarone, M; Severino, V; Sorbello, M; Spataro, M; Veroux, M; Veroux, P; Vizcarra, D	1
Afshari, NA; Heitman, J; Onyewu, C	1
Ichikawa, D; Kimura, K; Sato, T; Shima, Y; Tsuchida, H; Yasuda, T	1
Abouelfath, A; Depont, F; Dupon, M; Dutronc, H; Galpérine, T; Giauque, E; Hébert, G; Moore, N; Ragnaud, JM; Valentino, R; Vargas, F	1
Aisa, Y; Ikeda, Y; Iketani, O; Mihara, A; Mori, T; Okamoto, S; Tanigawara, Y; Yamazaki, R	1
Andes, D; Heitman, J; Nett, J; Uppuluri, P	1
Aoki, S; Hara, Y; Harada, Y; Igarashi, H; Katayama, M; Nezu, Y; Tagawa, M; Tani, K; Yogo, T	1
Hornick, JL; Narla, A; Pai, SY; Permaul, P	1
Fukai, K; Igarashi, H; Kamishina, H; Katayama, M; Momota, Y; Tagawa, M; Tani, K	1
Byekova, Y; Elewski, B; Hughey, L	1
Chauhan, NM; Karuppayil, SM; Raut, JS; Shinde, RB	1
Cao, C; Li, X; Liang, H; Mo, D; Sun, C; Wei, L	1
Baly, I; Daeli, PR; Kartasasmita, G; Wibawa, T; Wijayanti, N	1
Jia, W; Li, C; Li, G; Liu, X; Wei, J; Zhang, H	1
Behan, JW; Declerck, B; Kim, GH; Rodriguez, PG; Zhu, TH	1
Cafarchia, C; Iatta, R; Immediato, D; Otranto, D; Puttilli, MR	1
Kamei, H; Nishioka, H; Takegawa, H	1
Andrews, LM; Atiq, F; Broers, AEC; de Winter, BCM; Doorduijn, JK; Hameli, E; Koch, BCP; Van Gelder, T; Versmissen, J	1
Brings, A; Burhenne, J; Czock, D; Foerster, KI; Haefeli, WE; Lehmann, ML; Weiss, J	1
Ding, XL; Liu, LN; Miao, LY; Tian, JX; Xue, L; Yan, HH; Zhang, JJ; Zhang, WJ; Zhang, WW	1
Bubalo, JS; Gu, TM; Le, H; Lewis, JS	1

Reviews

5 review(s) available for fluconazole and cyclosporine

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
First report of Cryptococcus albidus--induced disseminated cryptococcosis in a renal transplant recipient. The Korean journal of internal medicine, 2004, Volume: 19, Issue:1 Topics: Adult; Antifungal Agents; Cryptococcosis; Cyclosporine; Diagnosis, Differential; Fluconazole; Graft Rejection; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney Transplantation; Lung Diseases, Fungal; Male; Opportunistic Infections; Tomography, X-Ray Computed	2004
Allogeneic hematopoietic stem cell transplantation for X-linked ectodermal dysplasia and immunodeficiency: case report and review of outcomes. Immunologic research, 2009, Volume: 44, Issue:1-3 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antifungal Agents; Azithromycin; Cyclosporine; Ectodermal Dysplasia; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; I-kappa B Kinase; Immunoglobulins, Intravenous; Immunologic Deficiency Syndromes; Immunologic Factors; Immunosuppressive Agents; Infant; Male; Methylprednisolone; Transplantation, Homologous; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination	2009
Systemic drugs in patients with skin diseases. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2011, Volume: 146, Issue:5 Topics: Cyclosporine; Fluconazole; Glucocorticoids; Humans; Immunologic Factors; Immunosuppression Therapy; Itraconazole; Methotrexate; Mycophenolic Acid; Naphthalenes; Retinoids; Skin Diseases; Terbinafine	2011

Trials

7 trial(s) available for fluconazole and cyclosporine

Article	Year
Evaluation of the drug interaction between intravenous high-dose fluconazole and cyclosporine or tacrolimus in bone marrow transplant patients. Transplantation, 1996, Apr-27, Volume: 61, Issue:8 Topics: Antifungal Agents; Bone Marrow Transplantation; Cyclosporine; Drug Interactions; Fluconazole; Graft Rejection; Humans; Immunosuppressive Agents; Prospective Studies; Tacrolimus; Transplantation, Homologous	1996
Unpredictable cyclosporin--fluconazole interaction in renal transplant recipients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14, Issue:7 Topics: Adult; Antifungal Agents; Biological Availability; Creatinine; Cross-Over Studies; Cyclosporine; Drug Interactions; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Prospective Studies	1999
Prophylactic fluconazole in liver transplant recipients. A randomized, double-blind, placebo-controlled trial. Annals of internal medicine, 1999, Nov-16, Volume: 131, Issue:10 Topics: Adolescent; Adult; Aged; Antifungal Agents; Cyclosporine; Female; Fluconazole; Headache; Humans; Liver Transplantation; Male; Middle Aged; Mycoses; Postoperative Complications; Proportional Hazards Models; Seizures; Statistics, Nonparametric; Tremor	1999
Effect of multiple oral dosing of fluconazole on the pharmacokinetics of cyclosporine in healthy beagles. The Journal of veterinary medical science, 2008, Volume: 70, Issue:1 Topics: Administration, Oral; Animals; Antifungal Agents; Area Under Curve; Biological Availability; Cross-Over Studies; Cyclosporine; Dogs; Drug Administration Schedule; Drug Interactions; Female; Fluconazole; Half-Life; Health; Immunosuppressive Agents	2008
Fluconazole decreases cyclosporine dosage in renal transplanted dogs. Research in veterinary science, 2010, Volume: 89, Issue:1 Topics: Animals; Antifungal Agents; Cyclosporine; Dogs; Drug Interactions; Female; Fluconazole; Immunosuppressive Agents; Kidney Transplantation; Male	2010
Perpetrator effects of ciclosporin (P-glycoprotein inhibitor) and its combination with fluconazole (CYP3A inhibitor) on the pharmacokinetics of rivaroxaban in healthy volunteers. British journal of clinical pharmacology, 2019, Volume: 85, Issue:7 Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Factor Xa Inhibitors; Female; Fluconazole; Humans; Male; Middle Aged; Models, Biological; Rivaroxaban; Young Adult	2019
Multicenter-Based Population Pharmacokinetic Analysis of Ciclosporin in Hematopoietic Stem Cell Transplantation Patients. Pharmaceutical research, 2019, Dec-23, Volume: 37, Issue:1 Topics: Adolescent; Adult; Aged; Body Weight; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluconazole; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Itraconazole; Male; Middle Aged; Models, Biological; Reproducibility of Results; Transplantation Conditioning; Voriconazole	2019

Other Studies

50 other study(ies) available for fluconazole and cyclosporine

Article	Year
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. Molecular pharmacology, 2002, Volume: 61, Issue:5 Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Ergonovine; Fluoxetine; Humans; Models, Molecular; Oxytocics; Protein Conformation; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Swine; Transfection; Vinblastine	2002
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1 Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydroergocryptine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Humans; Mice; Mice, Knockout; Microsomes, Liver; Oxidoreductases, N-Demethylating; Recombinant Proteins; Reserpine; Swine; Tissue Distribution; Transfection; Vinblastine	2002
Targeting the calcineurin pathway enhances ergosterol biosynthesis inhibitors against Trichophyton mentagrophytes in vitro and in a human skin infection model. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Antifungal Agents; Calcineurin; Colony Count, Microbial; Culture Media; Cyclosporine; Drug Synergism; Drug Therapy, Combination; Ergosterol; Fluconazole; Humans; Immunosuppressive Agents; Naphthalenes; Signal Transduction; Skin; Tacrolimus; Terbinafine; Tinea; Trichophyton	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The effects of the antifungal azoles itraconazole, fluconazole, ketoconazole and miconazole on cytokine gene expression in human lymphoid cells. International journal of immunopharmacology, 1992, Volume: 14, Issue:5 Topics: Antifungal Agents; Cells, Cultured; Cyclosporine; Cytokines; Fluconazole; Gene Expression; Humans; Itraconazole; Ketoconazole; Lymphocytes; Miconazole; Tacrolimus	1992
Reversible cyclosporine arteriolopathy. Transplantation, 1992, Volume: 54, Issue:4 Topics: Adult; Arterioles; Biopsy; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Fluconazole; Humans; Kidney Cortex; Kidney Transplantation; Male; Muscle, Smooth, Vascular; Pancreas Transplantation; Vascular Diseases	1992
Drug interactions with fluconazole. The Medical journal of Australia, 1992, Mar-02, Volume: 156, Issue:5 Topics: Cross-Sectional Studies; Cyclosporine; Drug Interactions; Fluconazole; Humans; Phenytoin; Theophylline; Warfarin	1992
Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes. British journal of clinical pharmacology, 1991, Volume: 32, Issue:5 Topics: Adult; Antifungal Agents; Cyclosporine; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Male; Microsomes, Liver; Naphthalenes; Terbinafine	1991
Interaction of fluconazole with ciclosporin A. Nephron, 1992, Volume: 60, Issue:1 Topics: Adult; Aged; Cyclosporine; Drug Interactions; Female; Fluconazole; Graft Survival; Humans; Kidney Transplantation; Middle Aged	1992
Fluconazole is removed by continuous venovenous hemofiltration in a liver transplant patient. Journal of molecular medicine (Berlin, Germany), 1995, Volume: 73, Issue:3 Topics: Anuria; Candidiasis; Ciprofloxacin; Cyclosporine; Fluconazole; Hemofiltration; Humans; Liver Transplantation; Male; Middle Aged; Vancomycin	1995
Candida albicans arthritis in a renal allograft recipient with an interaction between cyclosporin and fluconazole. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1993, Volume: 8, Issue:3 Topics: Arthritis, Infectious; Candidiasis; Cyclosporine; Drug Interactions; Female; Fluconazole; Humans; Kidney Transplantation; Middle Aged; Transplantation, Homologous	1993
Fluconazole-cyclosporine interaction: a dose-dependent effect? The Annals of pharmacotherapy, 1993, Volume: 27, Issue:4 Topics: Adult; Bone Marrow Transplantation; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluconazole; Humans; Kidney Transplantation; Mycoses; Pancreas Transplantation	1993
Ketoconazole and fluconazole inhibition of the metabolism of cyclosporin A by human liver in vitro. Therapeutic drug monitoring, 1997, Volume: 19, Issue:4 Topics: Adult; Antifungal Agents; Antirheumatic Agents; Chromatography, High Pressure Liquid; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Female; Fluconazole; Humans; Ketoconazole; Liver; Male; Microsomes, Liver; Middle Aged	1997
Effect of metabolic inhibitors on cyclosporine pharmacokinetics using a population approach. Therapeutic drug monitoring, 1998, Volume: 20, Issue:4 Topics: Administration, Oral; Adolescent; Adult; Aged; Antifungal Agents; Calcium Channel Blockers; Child; Cyclosporine; Diltiazem; Drug Administration Schedule; Drug Interactions; Fluconazole; Heart-Lung Transplantation; Humans; Immunosuppressive Agents; Individuality; Itraconazole; Ketoconazole; Linear Models; Middle Aged	1998
Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:1 Topics: Animals; Calcineurin Inhibitors; Cryptococcus neoformans; Cyclosporine; Drug Resistance, Microbial; Fluconazole; Humans; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Peptidylprolyl Isomerase; Temperature	2000
Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:9 Topics: Agar; Antifungal Agents; Candida albicans; Culture Media; Cyclosporine; Drug Synergism; Fluconazole; Humans; Time Factors	2000
Fluconazole plus cyclosporine: a fungicidal combination effective against experimental endocarditis due to Candida albicans. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:11 Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Cyclosporine; Disease Models, Animal; Drug Resistance, Microbial; Drug Therapy, Combination; Endocarditis; Female; Fluconazole; Kidney; Microbial Sensitivity Tests; Rats; Rats, Wistar; Treatment Outcome	2000
Extended routine polymerase chain reaction surveillance and pre-emptive antiviral therapy for cytomegalovirus after allogeneic transplantation. British journal of haematology, 2000, Volume: 111, Issue:3 Topics: Acyclovir; Adolescent; Adult; Antifungal Agents; Antiviral Agents; Bone Marrow Transplantation; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Female; Fluconazole; Foscarnet; Humans; Leukemia; Lymphoma; Male; Methotrexate; Middle Aged; Polymerase Chain Reaction; Postoperative Period; Prospective Studies; Risk; Survival Rate; Time Factors; Tissue Donors; Transplantation, Homologous	2000
Sex and ethnicity may chiefly influence the interaction of fluconazole with calcineurin inhibitors. Transplantation, 2001, Apr-27, Volume: 71, Issue:8 Topics: Adult; Antifungal Agents; Black or African American; Calcineurin Inhibitors; Cyclosporine; Drug Interactions; Ethnicity; Female; Fluconazole; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Pancreas Transplantation; Retrospective Studies; Sex Factors; Tacrolimus; United States	2001
Cyclosporin A-induced encephalopathy after allogeneic bone marrow transplantation with prevention of graft-versus-host disease by tacrolimus. Bone marrow transplantation, 2001, Volume: 28, Issue:7 Topics: Adult; Anemia, Aplastic; Anticonvulsants; Blood-Brain Barrier; Bone Marrow Transplantation; Brain Diseases; Brain Edema; Ceftazidime; Cerebral Hemorrhage; Cyclosporine; Diagnosis, Differential; Diuretics; Endothelium, Vascular; Epilepsy, Generalized; Female; Fluconazole; Graft vs Host Disease; Headache; Humans; Immunosuppressive Agents; Intracranial Hypertension; Magnetic Resonance Imaging; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous	2001
Calcineurin is essential for survival during membrane stress in Candida albicans. The EMBO journal, 2002, Feb-15, Volume: 21, Issue:4 Topics: Antifungal Agents; Base Sequence; Blotting, Northern; Calcineurin; Candida albicans; Cyclosporine; DNA Primers; Drug Resistance, Microbial; Fluconazole; Gene Expression Regulation, Fungal; Genes, Fungal; Methyltransferases; Tacrolimus	2002
Hepatobiliary excretion of fluconazole and its interaction with cyclosporin A in rat blood and bile using microdialysis. International journal of pharmaceutics, 2002, Jul-25, Volume: 241, Issue:2 Topics: Animals; Antifungal Agents; Area Under Curve; Bile; Chromatography, High Pressure Liquid; Cyclosporine; Drug Interactions; Fluconazole; Immunosuppressive Agents; Liver; Male; Microdialysis; Rats; Rats, Sprague-Dawley	2002
Fungicidal synergism of fluconazole and cyclosporine in Candida albicans is not dependent on multidrug efflux transporters encoded by the CDR1, CDR2, CaMDR1, and FLU1 genes. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:5 Topics: Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Candida albicans; Cyclosporine; Drug Resistance, Multiple; Drug Synergism; Drug Therapy, Combination; Endocarditis; Fluconazole; Fungal Proteins; Membrane Transport Proteins	2003
Cryptococcus neoformans methionine synthase: expression analysis and requirement for virulence. Microbiology (Reading, England), 2004, Volume: 150, Issue:Pt 9 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adaptation, Physiological; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Cyclosporine; Fluconazole; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Homocysteine; Hot Temperature; Melanins; Methionine; Mice; Microbial Sensitivity Tests; Mutation; RNA, Fungal; RNA, Messenger; Tacrolimus; Transcription, Genetic; Virulence; Virulence Factors	2004
Caspofungin in the treatment of azole-refractory esophageal candidiasis in kidney transplant recipients. Transplantation proceedings, 2006, Volume: 38, Issue:4 Topics: Adult; Aged; Antifungal Agents; Candidiasis; Candidiasis, Vulvovaginal; Caspofungin; Cyclosporine; Echinocandins; Esophageal Diseases; Female; Fluconazole; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Incidence; Kidney Transplantation; Lipopeptides; Middle Aged; Peptides, Cyclic; Postoperative Complications; Retrospective Studies; Tacrolimus; Time Factors	2006
Calcineurin promotes infection of the cornea by Candida albicans and can be targeted to enhance fluconazole therapy. Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:11 Topics: Animals; Antifungal Agents; Calcineurin; Calcineurin Inhibitors; Candida albicans; Candidiasis; Corneal Diseases; Cyclosporine; Fluconazole; Immunosuppressive Agents; Keratitis; Mice; Mice, Inbred BALB C	2006
[A case of cryptococcal meningitis with nephrotic syndrome and renal insufficiency under immunosuppressive therapy]. Nihon Jinzo Gakkai shi, 2007, Volume: 49, Issue:1 Topics: Aged; Amphotericin B; Antifungal Agents; Cryptococcus neoformans; Cyclosporine; Drug Administration Schedule; Female; Fluconazole; Humans; Immunosuppressive Agents; Meningitis, Cryptococcal; Nephrotic Syndrome; Prednisolone; Renal Insufficiency	2007
Drug-drug interactions with systemic antifungals in clinical practice. Pharmacoepidemiology and drug safety, 2007, Volume: 16, Issue:11 Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Creatinine; Cyclosporine; Drug Interactions; Female; Fluconazole; France; Furosemide; HIV Infections; Hospitals, University; Humans; Hydrocortisone; Hypokalemia; Intensive Care Units; Itraconazole; Kidney Diseases; Leukemia; Male; Middle Aged; Neoplasms; Retrospective Studies	2007
Greater impact of oral fluconazole on drug interaction with intravenous calcineurin inhibitors as compared with intravenous fluconazole. European journal of clinical pharmacology, 2008, Volume: 64, Issue:1 Topics: Antifungal Agents; Calcineurin Inhibitors; Cyclosporine; Drug Interactions; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infusions, Intravenous; Retrospective Studies; Tacrolimus	2008
Synergistic effect of calcineurin inhibitors and fluconazole against Candida albicans biofilms. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Animals; Antifungal Agents; Biofilms; Calcineurin Inhibitors; Candida albicans; Cyclosporine; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Humans; Microbial Sensitivity Tests; Rats; Tacrolimus	2008
Sensitization of Candida albicans biofilms to various antifungal drugs by cyclosporine A. Annals of clinical microbiology and antimicrobials, 2012, Oct-04, Volume: 11 Topics: Amphotericin B; Antifungal Agents; Biofilms; Candida albicans; Caspofungin; Cyclosporine; Drug Resistance, Multiple, Fungal; Drug Synergism; Echinocandins; Fluconazole; Lipopeptides; Microbial Sensitivity Tests; Nystatin; Pyrimidines; Triazoles; Voriconazole	2012
In vitro interactions of calcineurin inhibitors with conventional antifungal agents against the yeast form of Penicillium marneffei. Mycopathologia, 2014, Volume: 178, Issue:3-4 Topics: Antifungal Agents; Calcineurin Inhibitors; Cyclosporine; Drug Synergism; Fluconazole; Itraconazole; Microbial Sensitivity Tests; Penicillium; Tacrolimus; Yeasts	2014
Cyclosporine A decreases the fluconazole minimum inhibitory concentration of Candida albicans clinical isolates but not biofilm formation and cell growth. Tropical biomedicine, 2015, Volume: 32, Issue:1 Topics: Antifungal Agents; Biofilms; Candida albicans; Candidiasis; Cyclosporine; Drug Synergism; Fluconazole; Humans; Microbial Sensitivity Tests	2015
The calcineruin inhibitor cyclosporine a synergistically enhances the susceptibility of Candida albicans biofilms to fluconazole by multiple mechanisms. BMC microbiology, 2016, 06-18, Volume: 16, Issue:1 Topics: Antifungal Agents; Biofilms; Calcineurin Inhibitors; Candida albicans; Candidiasis; Cyclosporine; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Humans; Microbial Sensitivity Tests; Tacrolimus	2016
Cryptococcal cellulitis on the shin of an immunosuppressed patient. Dermatology online journal, 2016, Jun-15, Volume: 22, Issue:6 Topics: Amphotericin B; Antifungal Agents; Cellulitis; Cryptococcosis; Cryptococcus neoformans; Cyclosporine; Fluconazole; Flucytosine; Fungemia; Glomerulosclerosis, Focal Segmental; Humans; Immunocompromised Host; Immunosuppressive Agents; Leg Dermatoses; Male; Middle Aged; Prednisone; Skin	2016
The role of drug efflux pumps in Malassezia pachydermatis and Malassezia furfur defence against azoles. Mycoses, 2017, Volume: 60, Issue:3 Topics: Animals; Antifungal Agents; Cyclosporine; Dermatitis; Dermatomycoses; Dogs; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Genes, MDR; Haloperidol; Humans; Malassezia; Microbial Sensitivity Tests; Promethazine; Skin; Voriconazole	2017
Disseminated cryptococcosis in a patient taking tocilizumab for Castleman's disease. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2018, Volume: 24, Issue:2 Topics: Amphotericin B; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Antifungal Agents; Castleman Disease; Cryptococcosis; Cryptococcus neoformans; Cyclosporine; Fluconazole; Humans; Immunosuppressive Agents; Male; Middle Aged; Prednisolone; Risk Factors	2018
Converting cyclosporine A from intravenous to oral administration in hematopoietic stem cell transplant recipients and the role of azole antifungals. European journal of clinical pharmacology, 2018, Volume: 74, Issue:6 Topics: Administration, Intravenous; Administration, Oral; Adult; Aged; Antifungal Agents; Biological Availability; Cyclosporine; Drug Interactions; Female; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Voriconazole; Young Adult	2018
Comparative effects of fluconazole, posaconazole, and isavuconazole upon tacrolimus and cyclosporine serum concentrations. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2022, Volume: 28, Issue:6 Topics: Antifungal Agents; Cyclosporine; Fluconazole; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Nitriles; Pyridines; Retrospective Studies; Tacrolimus; Triazoles	2022