fluconazole and clinafloxacin

fluconazole has been researched along with clinafloxacin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's8 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Damu, GL; Geng, RX; Lv, JS; Wang, Y; Yang, DC; Zhou, CH1
Chang, JJ; Damu, GL; Geng, RX; Zhang, L; Zhang, SL; Zhou, CH1
Geng, RX; Kumar, KV; Zhang, L; Zhou, CH1
Addla, D; Cai, GX; Geng, RX; Li, S; Ponmani, J; Wang, A; Wang, YN; Xie, D; Zhang, L; Zhang, SL; Zhou, CH1
Ba, Y; Hou, X; Wang, S; Xu, Z; Yang, H; Zhang, J1

Reviews

1 review(s) available for fluconazole and clinafloxacin

ArticleYear
Nitroimidazole-containing compounds and their antibacterial and antitubercular activities.
    European journal of medicinal chemistry, 2019, Oct-01, Volume: 179

    Topics: Anti-Bacterial Agents; Bacterial Infections; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Molecular Structure; Nitroimidazoles

2019

Other Studies

9 other study(ies) available for fluconazole and clinafloxacin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Design, synthesis and evaluation of clinafloxacin triazole hybrids as a new type of antibacterial and antifungal agents.
    Bioorganic & medicinal chemistry letters, 2012, Sep-01, Volume: 22, Issue:17

    Topics: Anti-Bacterial Agents; Antifungal Agents; Bacterial Infections; Drug Design; Fluoroquinolones; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycoses; Staphylococcal Infections; Triazoles

2012
Synthesis and bioactive evaluation of novel hybrids of metronidazole and berberine as new type of antimicrobial agents and their transportation behavior by human serum albumin.
    Bioorganic & medicinal chemistry, 2013, Jul-15, Volume: 21, Issue:14

    Topics: Anti-Infective Agents; Bacteria; Berberine; Binding Sites; Biological Transport; Fungi; Humans; Magnetic Resonance Spectroscopy; Metronidazole; Molecular Structure; Serum Albumin; Thermodynamics

2013
Design and biological evaluation of novel quinolone-based metronidazole derivatives as potent Cu(2+) mediated DNA-targeting antibacterial agents.
    Bioorganic & medicinal chemistry letters, 2015, Sep-01, Volume: 25, Issue:17

    Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Chemistry Techniques, Synthetic; Ciprofloxacin; Copper; DNA, Bacterial; Drug Evaluation, Preclinical; Fibroblasts; Fluoroquinolones; HEK293 Cells; Humans; Metronidazole; Mice; Microbial Sensitivity Tests; Molecular Targeted Therapy; Norfloxacin; Pseudomonas aeruginosa; Quinolones; Structure-Activity Relationship

2015
Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents.
    European journal of medicinal chemistry, 2016, Mar-23, Volume: 111

    Topics: Anti-Bacterial Agents; Benzimidazoles; Binding Sites; DNA, Bacterial; Dose-Response Relationship, Drug; Drug Discovery; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Quinolones; Structure-Activity Relationship; Topoisomerase Inhibitors

2016