fluconazole and azd 6244

fluconazole has been researched along with azd 6244 in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Dymond, AW; Huang, Y; Lisbon, E; Mariani, G; Martin, P; Mathews, D; Severin, P; So, K	1
Cohen-Rabbie, S; Freshwater, T; Jain, L; Schalkwijk, S; Tomkinson, H; Vishwanathan, K; Wild, M; Xu, S; Zhou, D; Zhou, L	1

Trials

1 trial(s) available for fluconazole and azd 6244

Article	Year
Effects of cytochrome P450 (CYP3A4 and CYP2C19) inhibition and induction on the exposure of selumetinib, a MEK1/2 inhibitor, in healthy subjects: results from two clinical trials. European journal of clinical pharmacology, 2017, Volume: 73, Issue:2 Topics: Adolescent; Adult; Benzimidazoles; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inducers; Female; Fluconazole; Healthy Volunteers; Humans; Itraconazole; Male; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinase 2; Rifampin; Young Adult	2017

Article

Year

Effects of cytochrome P450 (CYP3A4 and CYP2C19) inhibition and induction on the exposure of selumetinib, a MEK1/2 inhibitor, in healthy subjects: results from two clinical trials.

European journal of clinical pharmacology, 2017, Volume: 73, Issue:2

Topics: Adolescent; Adult; Benzimidazoles; Cross-Over Studies; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C19 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inducers; Female; Fluconazole; Healthy Volunteers; Humans; Itraconazole; Male; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinase 2; Rifampin; Young Adult

2017

Other Studies

2 other study(ies) available for fluconazole and azd 6244

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physiologically Based Pharmacokinetic Modeling for Selumetinib to Evaluate Drug-Drug Interactions and Pediatric Dose Regimens. Journal of clinical pharmacology, 2021, Volume: 61, Issue:11 Topics: Adolescent; Age Factors; Area Under Curve; Benzimidazoles; Body Surface Area; Child; Child, Preschool; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Drug Dosage Calculations; Drug Interactions; Fluconazole; Humans; Itraconazole; Metabolic Clearance Rate; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Rifampin	2021

Article

Year

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

Chemical research in toxicology, 2010, Volume: 23, Issue:1

Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010

Physiologically Based Pharmacokinetic Modeling for Selumetinib to Evaluate Drug-Drug Interactions and Pediatric Dose Regimens.

Journal of clinical pharmacology, 2021, Volume: 61, Issue:11

Topics: Adolescent; Age Factors; Area Under Curve; Benzimidazoles; Body Surface Area; Child; Child, Preschool; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Drug Dosage Calculations; Drug Interactions; Fluconazole; Humans; Itraconazole; Metabolic Clearance Rate; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Rifampin

2021