Compounds > fluconazole

fluconazole and atorvastatin

fluconazole has been researched along with atorvastatin in 13 studies

Research

Studies (13)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (15.38)	29.6817
2010's	11 (84.62)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C	1
Beaumont, K; Di, L; Maurer, TS; Smith, DA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Egbert, M; Keserű, GM; Vajda, S; Whitty, A	1
Bäcklund, T; Kahri, J; Kivistö, KT; Valkonen, M; Vuoristo, M	1
Bruggisser, M; Franz, CC; Krähenbühl, S; Rätz Bravo, AE	1
Chang, HJ; Hsiao, SH; Hsieh, TH; Kao, SM; Wu, TJ; Yeh, PY	1
Alves, V; Araujo, GRS; Carneiro, HCS; Costa, MC; de Resende Stoianoff, MA; Ferreira, GF; Fontes, ACL; Frases, S; Magalhães, TFF; Oliveira, LV; Paixão, TA; Ribeiro, NQ; Santos, DA; Santos, JRA	1
Ismail, S; Küchler, P; Murarka, S; Nussbaumer, P; Schultz-Fademrecht, C; Triola, G; Waldmann, H; Wittinghofer, A; Zimmermann, G	1

Reviews

1 review(s) available for fluconazole and atorvastatin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

12 other study(ies) available for fluconazole and atorvastatin

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells). Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4 Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles	2013
Volume of Distribution in Drug Design. Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15 Topics: Drug Design; Half-Life; Pharmacokinetics	2015
Why Some Targets Benefit from beyond Rule of Five Drugs. Journal of medicinal chemistry, 2019, 11-27, Volume: 62, Issue:22 Topics: Binding Sites; Drug Discovery; Ligands; Molecular Weight; Protein Binding	2019
Rhabdomyolysis in a patient receiving atorvastatin and fluconazole. European journal of clinical pharmacology, 2005, Volume: 60, Issue:12 Topics: Antifungal Agents; Atorvastatin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Drug Synergism; Fatal Outcome; Fluconazole; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Male; Middle Aged; Mycoses; Pyrroles; Rhabdomyolysis	2005
[Rhabdomyolysis associated with atorvastatin combined with amiodarone and fluconazole]. Praxis, 2011, Mar-02, Volume: 100, Issue:5 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticholesteremic Agents; Antifungal Agents; Atorvastatin; Coronary Artery Bypass, Off-Pump; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Fluconazole; Heptanoic Acids; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Postoperative Complications; Pyrroles; Rhabdomyolysis	2011
Rhabdomyolysis caused by the moderate CYP3A4 inhibitor fluconazole in a patient on stable atorvastatin therapy: a case report and literature review. Journal of clinical pharmacy and therapeutics, 2016, Volume: 41, Issue:5 Topics: Aged; Atorvastatin; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Female; Fluconazole; Humans; Rhabdomyolysis	2016
Atorvastatin as a promising anticryptococcal agent. International journal of antimicrobial agents, 2017, Volume: 49, Issue:6 Topics: Animals; Anticholesteremic Agents; Antifungal Agents; Atorvastatin; Cryptococcosis; Cryptococcus gattii; Disease Models, Animal; Drug Repositioning; Drug Therapy, Combination; Fluconazole; Male; Mice, Inbred C57BL; Survival Analysis; Treatment Outcome	2017
Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEδ prenyl binding site. Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12 Topics: Atorvastatin; Benzimidazoles; Binding Sites; Cell Line, Tumor; Computer Simulation; Cyclic Nucleotide Phosphodiesterases, Type 6; Drug Design; Esters; Ethers; Heptanoic Acids; Humans; Kinetics; Models, Molecular; Protein Prenylation; Pyrroles; ras Proteins; Stereoisomerism; Structure-Activity Relationship; Thermodynamics	2014