fluconazole and ascorbic acid

fluconazole has been researched along with ascorbic acid in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (11.54)29.6817
2010's20 (76.92)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Liu, P; Peng, X; Tao, H; Wang, W; Wang, Y; Zhu, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ben Hadda, T; Chohan, Z; Ingle, V; Juneja, H; Parvez, A; Sheikh, J; Youssoufi, M1
Fronczek, FR; Indumathi, T; Jamal Ahamed, VS; Moon, SS; Rajendra Prasad, KJ1
Ganesh Kumar, C; Kamal, A; Murty, JN; Sujitha, P; Viswanath, A1
Lokanatha Rai, KM; Prashanth, MK; Revanasiddappa, HD; Veeresh, B1
Bhadraiah, UK; Javarasetty, C; Keshavamurthy, S; Ningaiah, S1
Ahmed, NM; Mohamed, MS; Youns, MM1
Harikrishna, N; Kotaiah, Y; Nagaraju, K; Venkata Rao, C; Vijjulatha, M; Yamini, L1
Bharathi, K; Haseena banu, B; Prasad, KV1
Bharate, SS; Vishwakarma, RA1
Kariyappa, AK; Nagamallu, R; Ningappa, MB; Srinivasan, B1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Damale, M; Kauthale, S; Pawar, R; Sangshetti, J; Tekale, S1
Cacciatore, I; Ciulla, M; Di Stefano, A; Epifano, F; Eusepi, P; Fiorito, S; Fornasari, E; Genovese, S; Marinelli, L; Mingoia, M; Örtücü, S; Pugnaloni, A; Simoni, S; Turkez, H1
Agafonova, NA; Borisevich, SS; Burgart, YV; Chupakhin, ON; Evstigneeva, NP; Gerasimova, NA; Krasnykh, OP; Kungurov, NV; Kushch, SO; Makhaeva, GF; Maslova, VV; Rudakova, EV; Saloutin, VI; Shchegolkov, EV; Solodnikov, SY; Triandafilova, GA; Ulitko, MV; Zilberberg, NV1
Clemente de Moraes, D; do Carmo Freire Ribeiro Pinto, M; do Valle Pereira Midlej, V; Ferreira-Pereira, A; Tenório Sousa Domingos, L1
Cao, YB; Cao, YY; Gao, PH; Jia, JH; Jia, XM; Jiang, YY; Li, MB; Liao, WQ; Wang, Y1
Dai, BD; Gao, PH; Jiang, YY; Liang, RM; Tang, RJ; Wang, Y; Xu, Y; Yan, L1
Fiori, A; Van Dijck, P; Van Hauwenhuyse, F1
Li, X; Sha, J; Sun, L; Tong, Z; Wang, C; Yang, X; Zhang, G; Zhou, K1
Chandrasekaran, S; Covington, MB; Dbouk, NH; Nguyen, K1
Ganeshkumar, A; Rajaram, R; Suvaithenamudhan, S1

Reviews

1 review(s) available for fluconazole and ascorbic acid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

25 other study(ies) available for fluconazole and ascorbic acid

ArticleYear
Cerebrosides of the halotolerant fungus Alternaria raphani isolated from a sea salt field.
    Journal of natural products, 2009, Volume: 72, Issue:9

    Topics: Alkaloids; Alternaria; Anti-Bacterial Agents; Bacillus subtilis; Candida albicans; Cerebrosides; Crystallography, X-Ray; Escherichia coli; Marine Biology; Microbial Sensitivity Tests; Molecular Structure; Salts; Seawater

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis, biopharmaceutical characterization, antimicrobial and antioxidant activities of 1-(4'-O-β-D-glucopyranosyloxy-2'-hydroxyphenyl)-3-aryl-propane-1,3-diones.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:4

    Topics: Anti-Infective Agents; Bacteria; Biphenyl Compounds; Free Radical Scavengers; Ketones; Picrates; Spectrum Analysis

2011
L-Proline anchored multicomponent synthesis of novel pyrido[2,3-a]carbazoles; investigation of in vitro antimicrobial, antioxidant, cytotoxicity and structure activity relationship studies.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:11

    Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Carbazoles; Cell Line, Tumor; Chemistry Techniques, Synthetic; Drug Design; Free Radical Scavengers; Fungi; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Proline; Structure-Activity Relationship

2011
Synthesis, biological evaluation of 5-carbomethoxymethyl-7-hydroxy-2-pentylchromone, 5-carboethoxymethyl-4',7-dihydroxyflavone and their analogues.
    Bioorganic & medicinal chemistry letters, 2012, Jul-15, Volume: 22, Issue:14

    Topics: Anti-Infective Agents; Antifungal Agents; Antioxidants; Chromones; Flavones; Flavonoids; Microbial Viability; Molecular Structure; Structure-Activity Relationship

2012
Synthesis, characterization, antidepressant and antioxidant activity of novel piperamides bearing piperidine and piperazine analogues.
    Bioorganic & medicinal chemistry letters, 2012, Dec-01, Volume: 22, Issue:23

    Topics: Amides; Animals; Anti-Bacterial Agents; Antidepressive Agents; Antifungal Agents; Antioxidants; Behavior, Animal; Candida albicans; Gram-Negative Bacteria; Gram-Positive Bacteria; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Piperazine; Piperazines; Piperidines

2012
Novel pyrazoline amidoxime and their 1,2,4-oxadiazole analogues: synthesis and pharmacological screening.
    Bioorganic & medicinal chemistry letters, 2013, Aug-15, Volume: 23, Issue:16

    Topics: Amides; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Bacteria; Biological Assay; Drug Evaluation, Preclinical; Fatty Acids; Fungi; Molecular Structure; Oxadiazoles; Oximes; Pyrazoles

2013
Synthesis, antimicrobial, antioxidant activities of novel 6-aryl-5-cyano thiouracil derivatives.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Bacteria; Biphenyl Compounds; Dose-Response Relationship, Drug; Free Radical Scavengers; Fungi; Microbial Sensitivity Tests; Molecular Structure; Picrates; Structure-Activity Relationship; Thiouracil

2013
Synthesis, docking and evaluation of antioxidant and antimicrobial activities of novel 1,2,4-triazolo[3,4-b][1,3,4]thiadiazol-6-yl)selenopheno[2,3-d]pyrimidines.
    European journal of medicinal chemistry, 2014, Mar-21, Volume: 75

    Topics: Anti-Infective Agents; Antioxidants; Bacteria; Bacterial Infections; Benzene Derivatives; Fungi; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycoses; Organoselenium Compounds; Pyrimidines; Thiadiazoles

2014
Synthesis and biological evaluation of N-dehydrodipeptidyl-N,N'-dicyclohexylurea analogs.
    European journal of medicinal chemistry, 2014, May-06, Volume: 78

    Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Bacteria; Carrageenan; Dose-Response Relationship, Drug; Edema; Fungi; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Pain; Rats; Structure-Activity Relationship; Urea

2014
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Synthesis of novel coumarin appended bis(formylpyrazole) derivatives: Studies on their antimicrobial and antioxidant activities.
    Bioorganic & medicinal chemistry letters, 2016, Jan-15, Volume: 26, Issue:2

    Topics: Anti-Infective Agents; Antioxidants; Bacteria; Bacterial Infections; Coumarins; Fungi; Humans; Microbial Sensitivity Tests; Mycoses; Pyrazoles; Quantitative Structure-Activity Relationship

2016
Synthesis, antioxidant, antifungal, molecular docking and ADMET studies of some thiazolyl hydrazones.
    Bioorganic & medicinal chemistry letters, 2017, 08-15, Volume: 27, Issue:16

    Topics: Antifungal Agents; Antioxidants; Aspergillus flavus; Aspergillus niger; Candida; Computer Simulation; Dose-Response Relationship, Drug; Hydrazones; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship

2017
Carvacrol prodrugs as novel antimicrobial agents.
    European journal of medicinal chemistry, 2019, Sep-15, Volume: 178

    Topics: Anti-Bacterial Agents; Antifungal Agents; Candida; Cymenes; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Monoterpenes; Prodrugs; Solubility; Structure-Activity Relationship

2019
Multiple biological active 4-aminopyrazoles containing trifluoromethyl and their 4-nitroso-precursors: Synthesis and evaluation.
    European journal of medicinal chemistry, 2020, Dec-15, Volume: 208

    Topics: Animals; Bacteria; Drug Screening Assays, Antitumor; Epidermophyton; HeLa Cells; Humans; Mice; Microbial Sensitivity Tests; Molecular Structure; Nitroso Compounds; Pyrazoles; Rats, Sprague-Dawley; Structure-Activity Relationship; Trichophyton

2020
Effects of β-lapachone and β-nor-lapachone on multidrug efflux transporters and biofilms of Candida glabrata.
    Bioorganic & medicinal chemistry, 2022, 06-01, Volume: 63

    Topics: Antifungal Agents; Biofilms; Candida albicans; Candida glabrata; Membrane Transport Proteins; Naphthoquinones; Saccharomyces cerevisiae

2022
Ascorbic acid decreases the antifungal effect of fluconazole in the treatment of candidiasis.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:10

    Topics: Animals; Antifungal Agents; Antioxidants; Ascorbic Acid; Candida albicans; Candidiasis; Disease Models, Animal; Drug Antagonism; Drug Evaluation, Preclinical; Drug Resistance, Fungal; Fluconazole; Mice; Microbial Sensitivity Tests

2009
Proteomic analysis reveals a synergistic mechanism of fluconazole and berberine against fluconazole-resistant Candida albicans: endogenous ROS augmentation.
    Journal of proteome research, 2009, Volume: 8, Issue:11

    Topics: Adenosine Triphosphate; Antifungal Agents; Antioxidants; Ascorbic Acid; Berberine; Candida albicans; Cell Respiration; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Fungal Proteins; Humans; Membrane Potential, Mitochondrial; Microbial Sensitivity Tests; Proteome; Reactive Oxygen Species

2009
Ascorbic acid inhibition of Candida albicans Hsp90-mediated morphogenesis occurs via the transcriptional regulator Upc2.
    Eukaryotic cell, 2014, Volume: 13, Issue:10

    Topics: Ascorbic Acid; Benzoquinones; Candida albicans; Cytochrome P-450 Enzyme System; Drug Resistance, Fungal; Ergosterol; Fluconazole; Fungal Proteins; Gene Expression Regulation, Fungal; HSP90 Heat-Shock Proteins; Hyphae; Lactams, Macrocyclic; Morphogenesis; Temperature; Trans-Activators

2014
Enhancing the colorimetric detection of H
    The Analyst, 2019, May-21, Volume: 144, Issue:10

    Topics: Ascorbic Acid; Biomimetic Materials; Biosensing Techniques; Catalysis; Colorimetry; Fluconazole; Humans; Hydrogen Peroxide; Kinetics; Limit of Detection; Metal-Organic Frameworks; Models, Chemical; Peroxidase; Polymers; Pyrroles

2019
Increase of reactive oxygen species contributes to growth inhibition by fluconazole in Cryptococcus neoformans.
    BMC microbiology, 2019, 11-06, Volume: 19, Issue:1

    Topics: Antifungal Agents; Ascorbic Acid; Cryptococcus neoformans; Fluconazole; Fungal Proteins; Gene Expression Regulation, Fungal; Glutathione; Metallothionein; Microbial Viability; Pyrrolidines; Reactive Oxygen Species; Thiocarbamates; Tretinoin

2019
In Vitro and In Silico Analysis of Ascorbic Acid Towards Lanosterol 14-α-Demethylase Enzyme of Fluconazole-Resistant Candida albicans.
    Current microbiology, 2021, Volume: 78, Issue:1

    Topics: Antifungal Agents; Ascorbic Acid; Candida albicans; Drug Resistance, Fungal; Fluconazole; Lanosterol; Microbial Sensitivity Tests; Molecular Docking Simulation; Sterol 14-Demethylase

2021