Page last updated: 2024-08-17

floxuridine and mercaptopurine

floxuridine has been researched along with mercaptopurine in 36 studies

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199024 (66.67)18.7374
1990's3 (8.33)18.2507
2000's4 (11.11)29.6817
2010's5 (13.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Grube, M; Guitton, J; Hübner, T; Jedlitschky, G; Köck, K; Kowalczyk, DW; Kroemer, HK; Lerch, MM; Mayerle, J; Mews, S; Nambaru, PK; Payen, L; Rimmbach, C; Ritter, CA; Rosskopf, D; Sendler, M; Weiss, FU1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Rosenberg, RN1
Jampel, HD; Koya, P; Leong, K; Quigley, HA1
Saneyoshi, M1
Aiba, K; Allegra, CJ; Baram, J; Chabner, BA; Curt, GA; Yeh, GC1
Johnson, RO; Sedransk, N; Shingleton, WW1
Greenwald, ES1
Buskirk, HH; Crim, JA; Johnson, AG; Merritt, K; Petering, HG1
Houlihan, RB; Roby, R; Teskey, C1
Modest, EJ1
Cappuccino, JG; Schmid, FA; Stock, CC; Tarnowski, GS1
Bradner, WT; Pindell, MH1
Cassidy, EP; Fischer, DS; Welch, AD1
Foley, GE; Lazarus, H1
Field, AK; Lampson, GP; Tytell, AA1
Hunt, DE; Pittillo, RF1
Dendy, PP1
Adamson, DJ; Bowdon, BJ; Vail, MH; Wheeler, GP1
Chu, MY; Hoovis, ML1
Belvedere, G; Bossi, A; Donelli, MG; Frigerio, A; Martini, A; Pantarotto, C1
Inui, N; Sato, S; Takizawa, H1
OWENS, AH; SANTOS, GW; SENSENBRENNER, LL1
ANDERSON, EP; BROCKMAN, RW1
KARNOFSKY, DA; SIMMEL, EB1
DIPAOLO, JA; DOWD, JE; WATNE, AL1
OWENS, AH; SANTOS, GW1
SUBAK-SHARPE, H1
HODAS, S; YOUNG, CW1
Chahoud, I; Paumgartten, FJ1

Reviews

4 review(s) available for floxuridine and mercaptopurine

ArticleYear
Antimetabolites.
    Cancer chemotherapy and biological response modifiers, 1987, Volume: 9

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Floxuridine; Fluorouracil; Folic Acid Antagonists; Humans; Mercaptopurine; Methotrexate; Purines; Thioguanine

1987
Cancer chemotherapy. II.
    New York state journal of medicine, 1972, Nov-01, Volume: 72, Issue:21

    Topics: Animals; Antineoplastic Agents; Asparaginase; Azathioprine; Bleomycin; Cytarabine; Dactinomycin; Daunorubicin; Dimethylamines; Doxorubicin; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Imidazoles; Mercaptopurine; Mitomycins; Mitotane; Neoplasms; Nitrosourea Compounds; Pipobroman; Procarbazine; Streptonigrin; Streptozocin; Thioguanine; Triazenes; Triazines; Vinblastine; Vincristine

1972
BIOCHEMISTRY OF CANCER (METABOLIC ASPECTS).
    Annual review of biochemistry, 1963, Volume: 32

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Floxuridine; Fluorouracil; Folic Acid; Glutamine; Leukemia L1210; Mercaptopurine; Methotrexate; Mitomycin; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Puromycin; Pyrimidines; Research; RNA; RNA, Neoplasm; Thioguanine; Thiouracil

1963
EFFECTS OF GROWTH-INHIBITING CHEMICALS ON THE SAND-DOLLAR EMBRYO, ECHINARACHNIUS PARMA.
    Progress in experimental tumor research, 1963, Volume: 3

    Topics: Adenine; Animals; Azaguanine; Bromodeoxyuridine; Colchicine; Dinitrophenols; Echinodermata; Embryo, Mammalian; Embryo, Nonmammalian; Enzyme Inhibitors; Floxuridine; Fluorouracil; Growth; Idoxuridine; Mercaptopurine; Pharmacology; Pyrimidines; Sea Urchins

1963

Other Studies

32 other study(ies) available for floxuridine and mercaptopurine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorouracil; Gene Knockdown Techniques; Humans; Multidrug Resistance-Associated Proteins; Pancreas; Pancreatic Neoplasms; RNA; RNA Interference; Tumor Cells, Cultured

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Neuroblastoma and glioma cell cultures in studies of neurologic functions: the clinician's Rosetta Stone?
    Neurology, 1977, Volume: 27, Issue:2

    Topics: Cell Line; Cells, Cultured; Drug Resistance; Floxuridine; Glioma; Humans; Mercaptopurine; Morphine Dependence; Neoplasms, Experimental; Nervous System Diseases; Neuroblastoma; Neurophysiology; Thioguanine; Vasoactive Intestinal Peptide

1977
In vitro release of hydrophobic drugs from polyanhydride disks.
    Ophthalmic surgery, 1991, Volume: 22, Issue:11

    Topics: Alkaloids; Cell Division; Cells, Cultured; Decanoic Acids; Delayed-Action Preparations; Dicarboxylic Acids; Drug Implants; Etoposide; Fibroblasts; Floxuridine; Fluorouracil; Glaucoma; Humans; Mercaptopurine; Paclitaxel; Polymers; Postoperative Complications; Vincristine

1991
[Enzyme inhibitors related to the nucleic acids biosynthesis and gene expression].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:9

    Topics: Animals; Chromatography, Affinity; Deoxyguanine Nucleotides; Deoxyuridine; DNA Repair; DNA Replication; DNA-Directed RNA Polymerases; Floxuridine; Mercaptopurine; Nucleic Acid Synthesis Inhibitors; RNA; RNA, Viral

1991
Systemic chemotherapy of mammary carcinoma.
    Annals of surgery, 1971, Volume: 173, Issue:6

    Topics: Amines; Antineoplastic Agents; Azirines; Azo Compounds; Breast Neoplasms; Caproates; Carbohydrates; Chlorambucil; Cyclophosphamide; Evaluation Studies as Topic; Floxuridine; Fluorouracil; Humans; Imidazoles; Mercaptopurine; Methotrexate; Mitomycins; Palliative Care; Prednisone; Triazines; Vincristine

1971
Effect of uracil mustard and several antitumor drugs on the primary antibody response in rats and mice.
    Journal of the National Cancer Institute, 1965, Volume: 34, Issue:6

    Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Carcinoma 256, Walker; Cyclophosphamide; Cytarabine; Endotoxins; Floxuridine; gamma-Globulins; Injections; Mercaptopurine; Mice; Rats; Thiosemicarbazones; Uracil Mustard

1965
Inhibition of plaque formation by myxoma and fibroma viruses with pyrimidine analogues.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 120, Issue:2

    Topics: Antiviral Agents; Benzimidazoles; Bromodeoxyuridine; Culture Techniques; Cytosine; DNA, Viral; Fibroma; Floxuridine; Fluorouracil; Idoxuridine; Mercaptopurine; Methotrexate; Myxoma virus; Nucleosides; Oncogenic Viruses; Thiosemicarbazones; Thymine

1965
Formal discussion: future prospects in leukemia chemotherapy.
    Cancer research, 1965, Volume: 25, Issue:9

    Topics: Animals; Dactinomycin; Floxuridine; Leukemia; Melphalan; Mercaptopurine; Methotrexate; Mitomycins; Neoplasm Metastasis; Pyrimidines; Sarcoma, Experimental; Thiotepa

1965
Chemotherapy studies in an animal tumor spectrum. II. Sensitivity of tumors to fourteen antitumor chemicals.
    Cancer research, 1966, Volume: 26, Issue:3 Pt 2

    Topics: Animals; Antineoplastic Agents; Arsenicals; Busulfan; Cyclophosphamide; Dactinomycin; Diethylstilbestrol; Floxuridine; Fluorouracil; Hydrocortisone; Mercaptopurine; Methotrexate; Mice; Mitomycins; Neoplasms, Experimental; Urethane; Vinblastine

1966
Myeloid leukemia C-1498 as a screen for cancer chemotherapeutic agents.
    Cancer research, 1966, Volume: 26, Issue:4 Pt 2

    Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Azaguanine; Azaserine; Busulfan; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Neoplasms, Experimental; Prednisone; Pyrazoles; Pyrimidines; Triethylenemelamine; Vinblastine; Vincristine

1966
Immunosuppression by pyrimidine nucleoside analogs.
    Biochemical pharmacology, 1966, Volume: 15, Issue:8

    Topics: Animals; Antibody Formation; Antimetabolites; Azathioprine; Bromodeoxyuridine; Chloramphenicol; Cytarabine; Cytosine Nucleotides; Erythrocytes; Floxuridine; Hemagglutination Tests; Idoxuridine; Injections, Intraperitoneal; Injections, Subcutaneous; Mercaptoethanol; Mercaptopurine; Methotrexate; Mice; Nucleosides; Sheep

1966
The response in vitro, of continuous cultures of human lymphoblasts (CCRF-CEM cells) to chemotherapeutic agents.
    Biochemical pharmacology, 1967, Volume: 16, Issue:4

    Topics: Animals; Azaserine; Chloramphenicol; Culture Media; Culture Techniques; Cyclophosphamide; Cytarabine; Dactinomycin; Deoxyuridine; Floxuridine; Fluorouracil; Humans; Hydrocortisone; Lymphocytes; Mechlorethamine; Mercaptopurine; Methotrexate; Mitomycins; Puromycin; Thymidine; Triazines; Vincristine

1967
Effect of metabolic inhibitors on interferon activity.
    Life sciences, 1967, Jul-15, Volume: 6, Issue:14

    Topics: Antifungal Agents; Antimetabolites; Biological Assay; Culture Techniques; Cycloheximide; Dactinomycin; DNA, Viral; Floxuridine; Idoxuridine; Interferons; Mercaptopurine; Mitomycins; Newcastle disease virus; Puromycin; RNA, Messenger; Sulfhydryl Compounds; Viral Proteins

1967
Determination of certain antitumor agents in mouse blood by microbiologic assay.
    Cancer research, 1968, Volume: 28, Issue:6

    Topics: Anilides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Assay; Floxuridine; Fluorouracil; Mercaptopurine; Methods; Methotrexate; Mice

1968
Responses of freshly cultured tumour cells to certain selected chemotherapeutic agents.
    The Journal of obstetrics and gynaecology of the British Commonwealth, 1968, Volume: 75, Issue:12

    Topics: Adenocarcinoma; Antineoplastic Agents; Chlorambucil; Colchicine; Culture Techniques; Cyclophosphamide; Dactinomycin; Female; Floxuridine; Fluorouracil; Hodgkin Disease; Humans; Melphalan; Mercaptopurine; Methotrexate; Nandrolone; Neoplasms; Nitrogen Mustard Compounds; Norethindrone; Prednisolone; Progesterone; Testosterone; Thiotepa; Uterine Neoplasms; Vinblastine

1968
Comparison of the effects of several inhibitors of the synthesis of nucleic acids upon the viability and progression through the cell cycle of cultured H. Ep. no. 2 cells.
    Cancer research, 1972, Volume: 32, Issue:12

    Topics: Antimetabolites; Azaguanine; Carcinoma; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Humans; Hydroxyurea; Laryngeal Neoplasms; Mercaptopurine; Methotrexate; Mitosis; Ribonucleosides; Thioguanine; Time Factors; Tritium

1972
Sensitivity of human leukemic cells to anti-cancer agents in culture.
    Biochemical pharmacology, 1974, Feb-01, Volume: 23, Issue:3

    Topics: Animals; Antineoplastic Agents; Azauridine; Cells; Cells, Cultured; Chlorambucil; Culture Media; Cyclophosphamide; Cytarabine; Drug Resistance; Floxuridine; Horses; Humans; Leukemia, Experimental; Mercaptopurine; Methotrexate; Mice; Prednisone; Thioguanine; Vincristine

1974
Application of gas chromatography-chemical ionization mass fragmentography in the evaluation of bases and nucleoside analogues used in cancer chemotherapy.
    Journal of chromatography, 1974, Nov-06, Volume: 99, Issue:0

    Topics: Animals; Antineoplastic Agents; Base Sequence; Chromatography, Gas; Cytarabine; Drug Evaluation; Floxuridine; Fluorouracil; Mass Spectrometry; Mercaptopurine; Methods; Methylation; Mice; Nucleosides; Purines; Pyrimidines; Ribonucleosides

1974
Mouse strain differences in induction of micronuclei by base analogues and nucleosides.
    Mutation research, 1993, Volume: 301, Issue:1

    Topics: Adenine; Animals; Bromodeoxyuridine; Bromouracil; Cytarabine; Erythrocytes; Female; Floxuridine; Guanosine; Mercaptopurine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Micronucleus Tests; Mitogens; Nucleosides; Purines; Pyrimidines; Species Specificity; Thymidine; Uridine

1993
EFFECTS OF SELECTED CYTOTOXIC AGENTS ON ANTIBODY PRODUCTION IN MAN; A PRELIMARY REPORT.
    Annals of the New York Academy of Sciences, 1964, Mar-31, Volume: 114

    Topics: Agglutination; Antibody Formation; Biomedical Research; Cyclophosphamide; Cytotoxins; Floxuridine; Fluorouracil; Francisella tularensis; Hemagglutination; Mechlorethamine; Mercaptopurine; Skin Tests

1964
INDIVIDUALIZED CHEMOTHERAPY BY IN VITRO DRUG SELECTION.
    Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20

    Topics: Antineoplastic Agents; Bone Neoplasms; Dactinomycin; Female; Floxuridine; Fluorouracil; Genital Neoplasms, Female; Humans; In Vitro Techniques; Intestinal Neoplasms; Leukemia; Mechlorethamine; Melanoma; Mercaptopurine; Methotrexate; Neoplasms; Pharyngeal Neoplasms; Respiratory Tract Neoplasms; Stomach Neoplasms; Thiotepa

1964
A COMPARISON OF THE EFFECTS OF SELECTED CYTOTOXIC AGENTS ON THE PRIMARY AGGLUTININ RESPONSE IN RATS INJECTED WITH SHEEP ERYTHROCYTES.
    Bulletin of the Johns Hopkins Hospital, 1964, Volume: 114

    Topics: Agglutinins; Animals; Antibodies; Antibody Formation; Antigen-Antibody Reactions; Antigens; Antineoplastic Agents; Cyclophosphamide; Cytotoxins; Erythrocytes; Floxuridine; Fluorouracil; Immunity; Immunization; Mechlorethamine; Mercaptopurine; Methotrexate; Purines; Rats; Research; Sheep; Toxicology; Vinblastine

1964
BIOCHEMICALLY MARKED VARIANTS OF THE SYRIAN HAMSTER FIBROBLAST CELL LINE BHK21 AND ITS DERIVATIVES.
    Experimental cell research, 1965, Volume: 38

    Topics: 2-Aminopurine; Amphotericin B; Animals; Antineoplastic Agents; Azaguanine; Bromodeoxyuridine; Carbon Isotopes; Cell Division; Cell Line; Cricetinae; Dactinomycin; Fibroblasts; Floxuridine; Fluorouracil; Hexoses; Hypoxanthines; Mercaptopurine; Mesocricetus; Metabolism; Mitomycin; Mitomycins; Mutation; Nucleosides; Pharmacology; Puromycin; Research; Thioguanine; Tissue Culture Techniques; Tritium; Vinblastine

1965
ACUTE EFFECTS OF CYTOTOXIC COMPOUNDS ON INCORPORATION OF PRECURSORS INTO DNA, RNA, AND PROTEIN OF HELA MONOLAYERS.
    Biochemical pharmacology, 1965, Volume: 14

    Topics: Anti-Bacterial Agents; Antimetabolites; Dactinomycin; DNA; Floxuridine; HeLa Cells; Humans; Leucine; Mercaptopurine; Metabolism; Methotrexate; Nucleosides; Pharmacology; Proteins; Puromycin; Research; RNA; Streptonigrin; Thymidine; Tissue Culture Techniques; Triethylenemelamine; Urethane; Uridine; Vinblastine

1965
Dose-response relationships of rat fetal skeleton variations: Relevance for risk assessment.
    Environmental research, 2009, Volume: 109, Issue:7

    Topics: Animals; Antineoplastic Agents; Bone and Bones; Dose-Response Relationship, Drug; Female; Floxuridine; Hydroxyurea; Maternal Exposure; Mercaptopurine; Pregnancy; Rats; Rats, Wistar

2009