floxuridine has been researched along with 5,10-methylenetetrahydrofolic acid in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujiwara, Y; Nishio, K; Ohe, Y; Ohmori, T; Saijo, N; Sugimoto, Y | 1 |
| Rustum, YM; Zhang, ZG | 1 |
| Harstrick, A; Rustum, YM; Zhang, ZG | 2 |
| Cheshire, PJ; de Graaf, SS; Houghton, JA; Houghton, PJ; Jadaud, P; Maneval, DC; Rodman, JH; Wainer, IW; Williams, LG | 1 |
| Barbour, KW; Berger, FG; Berger, SH | 1 |
| Barbour, KW; Berger, FG; Berger, SH; Hughey, CT | 1 |
| Malmberg, M; Rustum, YM; Slocum, HK; Yin, MB; Zhang, ZG | 1 |
8 other study(ies) available for floxuridine and 5,10-methylenetetrahydrofolic acid
| Article | Year |
|---|---|
In vitro enhancement of fluoropyrimidine-induced cytotoxicity by leucovorin in colorectal and gastric carcinoma cell lines but not in non-small-cell lung carcinoma cell lines.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Cell Survival; Colony-Forming Units Assay; Colorectal Neoplasms; Drug Synergism; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Leucovorin; Lung Neoplasms; Stomach Neoplasms; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1992 |
Pharmacologic rationale for fluoropyrimidine-leucovorin combination: biochemical mechanisms.
Topics: Cecal Neoplasms; Drug Administration Schedule; Drug Synergism; Floxuridine; Humans; Ileal Neoplasms; Kidney Neoplasms; Leucovorin; Stereoisomerism; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1992 |
Modulation of fluoropyrimidines: role of dose and schedule of leucovorin administration.
Topics: Clinical Trials as Topic; Drug Administration Schedule; Floxuridine; Humans; Leucovorin; Tetrahydrofolates; Tumor Cells, Cultured | 1992 |
Mechanisms of resistance to fluoropyrimidines.
Topics: Cecal Neoplasms; Deoxyuracil Nucleotides; Drug Resistance; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Ileal Neoplasms; Leucovorin; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1992 |
Relationship between dose rate of [6RS]Leucovorin administration, plasma concentrations of reduced folates, and pools of 5,10-methylenetetrahydrofolates and tetrahydrofolates in human colon adenocarcinoma xenografts.
Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Female; Floxuridine; Half-Life; Humans; Injections, Intravenous; Leucovorin; Mice; Mice, Inbred CBA; Tetrahydrofolates; Thymidylate Synthase; Time Factors | 1990 |
A naturally occurring variation in thymidylate synthase structure is associated with a reduced response to 5-fluoro-2'-deoxyuridine in a human colon tumor cell line.
Topics: Blotting, Northern; Blotting, Southern; Colonic Neoplasms; Drug Resistance; Floxuridine; Gene Amplification; Genes; Isoelectric Point; RNA, Messenger; Substrate Specificity; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured | 1988 |
Functional effects of a naturally occurring amino acid substitution in human thymidylate synthase.
Topics: Base Sequence; Binding Sites; Floxuridine; Fluorouracil; Histidine; Humans; Hydrogen-Ion Concentration; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Temperature; Tetrahydrofolates; Thymidylate Synthase; Tumor Cells, Cultured; Tyrosine | 1993 |
Isolation and characterization of a human ileocecal carcinoma cell line (HCT-8) subclone resistant to fluorodeoxyuridine.
Topics: Antimetabolites, Antineoplastic; Cell Division; Colonic Neoplasms; Drug Resistance; Floxuridine; Fluorouracil; Humans; Methotrexate; Quinazolines; Tetrahydrofolates; Thiophenes; Thymidine Kinase; Thymidine Phosphorylase; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |