Compounds > fleroxacin

fleroxacin and erythromycin

fleroxacin has been researched along with erythromycin in 15 studies

Research

Studies (15)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (20.00)	18.7374
1990's	3 (20.00)	18.2507
2000's	5 (33.33)	29.6817
2010's	4 (26.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Jolivette, LJ; Ward, KW	1
Jolivette, LJ; Nagilla, R; Ward, KW	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Bale, MJ; Erwin, ME; Gerlach, EH; Jones, RN; Koontz, FP; Murray, PR; Washington, JA	1
Edelstein, MA; Edelstein, PH	1
Brunham, RC; Le Saux, NM; Plummer, FA; Ronald, AR; Slaney, LA	1
Pohlod, DJ; Saravolatz, LD; Somerville, MM	1
Meier-Ewert, H; Steele-Mortimer, O	1
Agneter, E; Burgdorff, T; Eichler, HG; Georgopoulos, A; Haag, O; Jansen, B; Müller, M; Pehamberger, H; Stanek, G; Weninger, W	1

Trials

1 trial(s) available for fleroxacin and erythromycin

Article	Year
Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12 Topics: Adipose Tissue; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Cefotaxime; Cefpirome; Cellulitis; Cephalosporins; Erythromycin; Female; Fleroxacin; Humans; Macrolides; Male; Microdialysis; Muscle, Skeletal; Skin	1996

Other Studies

14 other study(ies) available for fleroxacin and erythromycin

Article	Year
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Comparative evaluation of oral systemic exposure of 56 xenobiotics in rat, dog, monkey and human. Xenobiotica; the fate of foreign compounds in biological systems, 2005, Volume: 35, Issue:2 Topics: Administration, Oral; Animals; Area Under Curve; Dogs; Haplorhini; Humans; Models, Statistical; Rats; Software; Species Specificity; Xenobiotics	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
MIC quality control guidelines for Haemophilus susceptibility tests using cefdinir (FK482), cefepime, cefetamet, cefpirome, ceftibuten, fleroxacin, temafloxacin, clarithromycin, RP59500, and trospectomycin. Journal of clinical microbiology, 1992, Volume: 30, Issue:1 Topics: Anti-Bacterial Agents; Cefdinir; Cefpirome; Ceftibuten; Ceftizoxime; Cephalosporins; Clarithromycin; Erythromycin; Fleroxacin; Fluoroquinolones; Haemophilus; Humans; Microbial Sensitivity Tests; Quality Control; Quinolones; Spectinomycin; Virginiamycin	1992
In vitro activity of Ro 23-9424 against clinical isolates of Legionella species. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:11 Topics: Animals; Anti-Infective Agents; Cefotaxime; Colony Count, Microbial; Culture Media; Erythromycin; Extracellular Space; Fleroxacin; Fluoroquinolones; Guinea Pigs; Intracellular Fluid; Legionella; Macrophages, Alveolar; Microbial Sensitivity Tests	1992
In vitro activity of ceftriaxone, cefetamet (Ro 15-8074), ceftetrame (Ro 19-5247; T-2588), and fleroxacin (Ro 23-6240; AM-833) versus Neisseria gonorrhoeae and Haemophilus ducreyi. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:7 Topics: Cefmenoxime; Ceftizoxime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Erythromycin; Fleroxacin; Haemophilus ducreyi; Humans; Neisseria gonorrhoeae; Penicillins; Spectinomycin; Tetracycline	1987
Inhibition of Legionella pneumophila multiplication within human macrophages by fleroxacin. The Journal of antimicrobial chemotherapy, 1988, Volume: 22 Suppl D Topics: Anti-Infective Agents; Cefoxitin; Ciprofloxacin; Erythromycin; Fleroxacin; Humans; Legionella; Macrophages; Microbial Sensitivity Tests; Rifampin	1988
In-vitro activity of fleroxacin against Chlamydia trachomatis. The Journal of antimicrobial chemotherapy, 1988, Volume: 22 Suppl D Topics: Anti-Infective Agents; Chlamydia trachomatis; Ciprofloxacin; Clindamycin; Drug Resistance, Microbial; Erythromycin; Fleroxacin; Microbial Sensitivity Tests; Tetracyclines	1988