flecainide and sodium bicarbonate

flecainide has been researched along with sodium bicarbonate in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's5 (20.00)18.2507
2000's3 (12.00)29.6817
2010's13 (52.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Heinemeyer, G; Köppel, C; Oberdisse, U1
Fifield, J; Pentel, PR; Salerno, DM1
Keyler, DE; Pentel, PR1
Johnston, A; Muhiddin, KA; Turner, P1
Johnston, RB; Keyler, DE; Murakami, MM; Pentel, PR; Salerno, DM1
Berlin, R; Brubacher, JR; Lovecchio, F; Sholar, JB1
Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C1
Auzinger, GM; Scheinkestel, CD1
Buffo-Sequiera, I; D'Alessandro, LC; Freeman, D; Gloor, J; Rieder, MJ1
Gay, KP; Kit, YC; Leung, MK; Tak, WY; Yin, LH1
Augustine, D; Bond, R; Walker, S1
Banks, CJ; Close, BR1
Hoffman, RS; Jang, DH; Nelson, LS1
Bonnefoy, E; Courand, PY; Kirkorian, G; Mullier, A; Ranc, S; Sibellas, F1
Cave, G; Harvey, M; Heys, D; Quinn, P1
Bernard, KR; Brumfield, E; Kabrhel, C1
Panakos, A; Pavri, BB; Ragupathi, L; Valentino, MA; Williams, J1
Kay, GN; McElderry, HT; Watts, TE1
Langørgen, J; Viland, J; Wendelbo, Ø1
Heldens, M; Melman, PG; van der Nat, GAM1
Cosyns, B; Michiels, V; Wilgenhof, A1
Fan, EH; Liu, JS1
Georgakakos, PK; McCabe, DJ; Radke, JB; Walsh, RD; Wilson, BZ1

Reviews

3 review(s) available for flecainide and sodium bicarbonate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Severe flecainide acetate poisoning. Apropos of a case].
    Archives des maladies du coeur et des vaisseaux, 1999, Volume: 92, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Biological Availability; Calcium Gluconate; Charcoal; Combined Modality Therapy; Consciousness Disorders; Diabetic Nephropathies; Drug Interactions; Drug Therapy, Combination; Flecainide; Heart Block; Hemofiltration; Humans; Hypertension; Hypotension; Intestinal Pseudo-Obstruction; Kidney Failure, Chronic; Male; Poisoning; Pulmonary Edema; Renal Dialysis; Respiration, Artificial; Sodium Bicarbonate; Sodium Channel Blockers; Uremia

1999
Flecainide Toxicity: A Case Report and Systematic Review of its Electrocardiographic Patterns and Management.
    Cardiovascular toxicology, 2017, Volume: 17, Issue:3

    Topics: Anti-Arrhythmia Agents; Disease Management; Electrocardiography; Flecainide; Humans; Male; Middle Aged; Sodium Bicarbonate; Tachycardia, Ventricular

2017

Trials

1 trial(s) available for flecainide and sodium bicarbonate

ArticleYear
Lack of effect of hypertonic sodium bicarbonate on QRS duration in patients taking therapeutic doses of class IC antiarrhythmic drugs.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:9

    Topics: Aged; Aged, 80 and over; Anilides; Anti-Arrhythmia Agents; Bicarbonates; Double-Blind Method; Electrocardiography; Encainide; Female; Flecainide; Humans; Hypertonic Solutions; Male; Middle Aged; Pilot Projects; Risk Factors; Sodium; Sodium Bicarbonate; Time Factors

1990

Other Studies

21 other study(ies) available for flecainide and sodium bicarbonate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Clinical course and outcome in class IC antiarrhythmic overdose.
    Journal of toxicology. Clinical toxicology, 1990, Volume: 28, Issue:4

    Topics: Ajmaline; Anti-Arrhythmia Agents; Bicarbonates; Bradycardia; Drug Overdose; Flecainide; Hemoperfusion; Humans; Hypertonic Solutions; Nausea; Prajmaline; Propafenone; Resuscitation; Retrospective Studies; Sodium; Sodium Bicarbonate; Tachycardia; Vomiting

1990
Hypertonic sodium bicarbonate partially reverses QRS prolongation due to flecainide in rats.
    Life sciences, 1989, Volume: 45, Issue:17

    Topics: Animals; Arrhythmias, Cardiac; Bicarbonates; Blood Pressure; Electrocardiography; Flecainide; Heart; Hypertonic Solutions; Male; Rats; Sodium; Sodium Bicarbonate

1989
The influence of urinary pH on flecainide excretion and its serum pharmacokinetics.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:4

    Topics: Adult; Ammonium Chloride; Bicarbonates; Female; Flecainide; Humans; Hydrogen-Ion Concentration; Kinetics; Male; Piperidines; Sodium Bicarbonate

1984
Reversal of flecainide-induced ventricular arrhythmia by hypertonic sodium bicarbonate in dogs.
    The American journal of emergency medicine, 1995, Volume: 13, Issue:3

    Topics: Animals; Cardiac Pacing, Artificial; Disease Models, Animal; Dogs; Electrocardiography; Flecainide; Hypertonic Solutions; Sodium Bicarbonate; Sodium Chloride; Tachycardia, Ventricular

1995
Hypertonic sodium bicarbonate in an acute flecainide overdose.
    The American journal of emergency medicine, 1998, Volume: 16, Issue:5

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Buffers; Drug Overdose; Electrocardiography; Emergency Treatment; Female; Flecainide; Humans; Hypertonic Solutions; Male; Sodium Bicarbonate; Suicide, Attempted

1998
Successful extracorporeal life support in a case of severe flecainide intoxication.
    Critical care medicine, 2001, Volume: 29, Issue:4

    Topics: Acidosis; Adult; Anti-Arrhythmia Agents; Drug Overdose; Electrocardiography; Epinephrine; Extracorporeal Membrane Oxygenation; Flecainide; Humans; Male; Respiration, Artificial; Sodium Bicarbonate; Suicide, Attempted; Treatment Outcome

2001
Life-threatening flecainide intoxication in a young child secondary to medication error.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:9

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Bradycardia; Cardiopulmonary Resuscitation; Child, Preschool; Drug Overdose; Flecainide; Humans; Male; Medication Errors; Sodium Bicarbonate; Syringes; Tachycardia

2009
CASH as a mnemonic for indications of sodium bicarbonate for sodium channel blocker intoxication.
    The American journal of emergency medicine, 2009, Volume: 27, Issue:8

    Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Flecainide; Humans; Magnesium; Male; Poisoning; Sodium Bicarbonate

2009
Iatrogenic Flecainide toxicity.
    Heart (British Cardiac Society), 2010, Volume: 96, Issue:24

    Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Confusion; Female; Flecainide; Hallucinations; Humans; Shock; Sodium Bicarbonate

2010
Pediatric flecainide toxicity from a double dose.
    The American journal of emergency medicine, 2012, Volume: 30, Issue:9

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Emergency Service, Hospital; Flecainide; Heart; Humans; Infant; Male; Prescription Drug Misuse; Sodium Bicarbonate

2012
A case of near-fatal flecainide overdose in a neonate successfully treated with sodium bicarbonate.
    The Journal of emergency medicine, 2013, Volume: 44, Issue:4

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Overdose; Flecainide; Humans; Infant, Newborn; Male; Medication Errors; Sodium Bicarbonate; Treatment Outcome

2013
Arrhythmogenic effect of flecainide toxicity.
    Cardiology journal, 2013, Volume: 20, Issue:2

    Topics: Adenosine Triphosphate; Aged; Anti-Arrhythmia Agents; Bundle-Branch Block; Electrocardiography; Female; Flecainide; Humans; Injections, Intravenous; Sodium Bicarbonate; Tachycardia, Ventricular; Treatment Outcome

2013
Hypertonic sodium bicarbonate versus intravenous lipid emulsion in a rabbit model of intravenous flecainide toxicity: no difference, no sink.
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Antidotes; Blood Pressure; Disease Models, Animal; Endpoint Determination; Fat Emulsions, Intravenous; Female; Flecainide; Heart Rate; Hypertonic Solutions; Male; Poisoning; Rabbits; Sodium Bicarbonate

2013
Life-threatening flecainide overdose treated with intralipid and extracorporeal membrane oxygenation.
    The American journal of emergency medicine, 2015, Volume: 33, Issue:12

    Topics: Adult; Anti-Arrhythmia Agents; Drug Overdose; Electrocardiography; Extracorporeal Membrane Oxygenation; Fat Emulsions, Intravenous; Female; Flecainide; Heart Arrest; Humans; Sodium Bicarbonate

2015
An Irregular Wide Complex Tachycardia.
    Circulation, 2017, 08-22, Volume: 136, Issue:8

    Topics: Action Potentials; Administration, Intravenous; Aged; Anti-Arrhythmia Agents; Electrocardiography; Female; Flecainide; Heart Rate; Humans; Sodium Bicarbonate; Tachycardia, Ventricular; Time Factors

2017
A somnolent woman in her fifties with acute circulatory failure.
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2019, May-28, Volume: 139, Issue:9

    Topics: Anti-Arrhythmia Agents; Charcoal; Drug Overdose; Electrocardiography; Female; Flecainide; Humans; Middle Aged; Pacemaker, Artificial; Shock; Sleepiness; Sodium Bicarbonate

2019
Renal failure, shock, and loss of pacemaker capture: A case of flecainide intoxication.
    The Netherlands journal of medicine, 2019, Volume: 77, Issue:5

    Topics: Aged; Anti-Arrhythmia Agents; Bradycardia; Buffers; Cardiotonic Agents; Drug Overdose; Electrocardiography; Fat Emulsions, Intravenous; Female; Flecainide; Humans; Kidney Failure, Chronic; Renal Elimination; Shock, Cardiogenic; Sick Sinus Syndrome; Sodium Bicarbonate; Treatment Outcome

2019
An irregular, extremely broad QRS complex rhythm.
    The American journal of emergency medicine, 2019, Volume: 37, Issue:10

    Topics: Accidental Falls; Aged; Anti-Arrhythmia Agents; Drug Overdose; Electrocardiography; Fatigue; Female; Flecainide; Humans; Sodium Bicarbonate; Tachycardia, Ventricular; Treatment Outcome

2019
Toxic Effects of Flecainide in a Patient With Kidney Failure and Tachyarrhythmia.
    JAMA internal medicine, 2021, 11-01, Volume: 181, Issue:11

    Topics: Aged; Atrial Flutter; Diagnosis, Differential; Dose-Response Relationship, Drug; Female; Flecainide; Humans; Renal Insufficiency; Risk Adjustment; Risk Factors; Sodium Bicarbonate; Tachycardia, Supraventricular; Tachycardia, Ventricular; Voltage-Gated Sodium Channel Blockers

2021
Flecainide poisoning and prolongation of elimination due to alkalinization.
    The American journal of emergency medicine, 2022, Volume: 56

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Overdose; Electrocardiography; Flecainide; Humans; Sodium Bicarbonate

2022