flecainide and procainamide

flecainide has been researched along with procainamide in 63 studies

Research

Studies (63)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (34.92)	18.7374
1990's	9 (14.29)	18.2507
2000's	15 (23.81)	29.6817
2010's	14 (22.22)	24.3611
2020's	3 (4.76)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Nagashima, R; Nishikawa, T; Tobita, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Sen, S; Sinha, N	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Arita, M; Kiyosue, T; Sato, T; Wu, B	1
Keefe, DL; Miura, D; Somberg, JC	1
Hess, J; Polak, PE; Stewart, PA	1
Somberg, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Roy, D	1
Echt, DS; Roden, DM; Woosley, RL	1
Morganroth, J; Nestico, PF	2
Huang, SK; Marcus, FI	1
Light, RT; Onrot, J; Robertson, D; Robertson, RM; Tantengco, MV	1
Kates, RE	1
Sacher, H; Schwarz, J; Somberg, JC; Tepper, D	1
Podrid, PJ	1
Collignon, P; Legrand, V	1
Atarashi, H; Hayakawa, H	1
Flowers, D; Keefe, D; Miura, D; Mizruchi, M; Somberg, J; Torres, V; Wynn, J	1
Flowers, D; Miura, D; O'Gallagher, D; Somberg, JC; Torres, V	1
Hillis, WS; Whiting, B	1
Somberg, JC	1
DiMarco, JP; Sellers, TD	1
Block, PJ; Winkle, RA	1
Banitt, EH; Kvam, DC; Schmid, JR	1
Grey, E; Silverman, DI	1
Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Sakai, R; Shirayama, T	1
Bel, KJ; Crijns, HJ; de Langen, CD; Ebels, T; Grandjean, JG; Lie, KI; Wesseling, H	1
Costa, A; Madrid, AH; Marín-Huerta, E; Mestre, JL; Moro, C; Novo, L	1
Greenberg, RM; Greenspon, AJ; Kidwell, GA; Volosin, KJ	1
D'Andrea, A; Ducceschi, V; Iacono, A; Liccardo, B; Santangelo, L; Sarubbi, B	1
Fujiki, A; Hayashi, H; Inoue, H; Mizumaki, K; Nagasawa, H; Usui, M	1
Erzouki, HK; Goldberg, SR; Schindler, CW	1
Dell'Orfano, JT; Luck, JC; Naccarelli, GV; Patel, HM; Wolbrette, DL	1
Kanke, M; Sugiyama, T; Tsuchimoto, K; Yoshiyama, Y	1
Antzelevitch, C; Fish, JM	1
Benito, B; Brugada, J; Brugada, P; Brugada, R; Gonzalez, M; Huikuri, HV; Junttila, MJ; Lizotte, E; Sarkozy, A; Vernooy, K	1
Behr, ER; Camm, AJ	1
Faggioni, M; Hasdemir, C; Hwang, HS; Knollmann, BC; Laver, D; Mehra, D; Turhan, K; Yin, H	1
Reiffel, JA	1
Aslani, A; Emkanjoo, Z; Hashemi, A; Saber, S; Shahrzad, S; Taban, S	1
Osadchii, OE	3
Ferreira-Gonzalez, I; Francisco-Pasqual, J; García-Dorado, D; Martin-Sanchez, G; Moya-Mitjans, A; Oristrell, G; Perez-Rodon, J; Rivas-Gandara, N; Roca-Luque, I; Rodríguez-García, J; Santos-Ortega, A	1
Kumar, B; Lokhandwala, Y	1
Chokesuwattanaskul, R; Leelapatana, P; Prechawat, S; Rungpradubvong, V; Thapanasuta, M	1

Reviews

13 review(s) available for flecainide and procainamide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The treatment of ventricular rhythm disturbances. American heart journal, 1986, Volume: 111, Issue:6 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Electric Countershock; Electric Stimulation; Electrocardiography; Exercise Test; Flecainide; Heart Ventricles; Humans; Lidocaine; Phenytoin; Piperidines; Procainamide; Quinidine; Risk; Tachycardia; Tocainide; United States; Ventricular Fibrillation; Verapamil	1986
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Antiarrhythmic drugs. Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2 Topics: Action Potentials; Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium Channel Blockers; Cell Membrane; Disopyramide; Electrophysiology; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide	1986
Effects of congestive heart failure on the pharmacokinetics and pharmacodynamics of antiarrhythmic agents. The American journal of cardiology, 1986, Jan-31, Volume: 57, Issue:3 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Digitalis; Disopyramide; Drug Interactions; Encainide; Flecainide; Half-Life; Heart Failure; Hemodynamics; Humans; Kidney; Kinetics; Lidocaine; Liver; Piperidines; Plants, Medicinal; Plants, Toxic; Potassium; Procainamide; Quinidine; Regional Blood Flow; Tocainide	1986
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment. Cardiology clinics, 1986, Volume: 4, Issue:2 Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil	1986
Antiarrhythmic drug therapy of ventricular arrhythmias. Current problems in cardiology, 1986, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil	1986
Antiarrhythmic agents for chronic ventricular arrhythmias. Comprehensive therapy, 1987, Volume: 13, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide	1987
Hemodynamic effects of antiarrhythmic drugs. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide	1983
Atrial fibrillation: what are the effects of drug therapy on the effectiveness and complications of electrical cardioversion? The Canadian journal of cardiology, 1998, Volume: 14, Issue:10 Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Digoxin; Electric Countershock; Flecainide; Humans; Procainamide; Quinidine; Verapamil	1998
Cost-effective management of acute atrial fibrillation: role of rate control, spontaneous conversion, medical and direct current cardioversion, transesophageal echocardiography, and antiembolic therapy. The American journal of cardiology, 2000, May-25, Volume: 85, Issue:10A Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cost-Benefit Analysis; Echocardiography, Transesophageal; Electric Countershock; Flecainide; Humans; Procainamide; Propafenone; Quinidine; Sotalol; Verapamil	2000
Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias. Circulation, 2008, Apr-08, Volume: 117, Issue:14 Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death, Sudden, Cardiac; Electrocardiography; Fatal Outcome; Female; Fever; Flecainide; Heart Arrest; Humans; Male; Methadone; Middle Aged; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Procainamide; Propofol; Sodium Channel Blockers; Sodium Channels; Water-Electrolyte Imbalance	2008

Trials

1 trial(s) available for flecainide and procainamide

Article	Year
Comparison of flecainide and procainamide in cardioversion of atrial fibrillation. European heart journal, 1993, Volume: 14, Issue:8 Topics: Adult; Aged; Atrial Fibrillation; Atrial Function, Left; Echocardiography; Electrocardiography; Female; Flecainide; Humans; Male; Middle Aged; Procainamide	1993

Other Studies

49 other study(ies) available for flecainide and procainamide

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs. Cardiovascular research, 1992, Volume: 26, Issue:11 Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Dinitrophenols; Disopyramide; Flecainide; Glyburide; Guinea Pigs; Heart Ventricles; Imidazoles; Lidocaine; Mexiletine; Myocardium; Piperidines; Potassium; Procainamide; Pyridines	1992
Complete atrioventricular dissociation and His bundle tachycardia in a newborn: problems in prenatal diagnosis and postnatal management. International journal of cardiology, 1989, Volume: 22, Issue:2 Topics: Atrioventricular Node; Bundle of His; Cesarean Section; Diagnosis, Differential; Digoxin; Echocardiography; Electrocardiography; Female; Flecainide; Heart Conduction System; Humans; Infant, Newborn; Infusions, Intravenous; Pregnancy; Prenatal Diagnosis; Procainamide; Tachycardia	1989
Orthostatic hypotension: clinical spectrum and approach to treatment. Comprehensive therapy, 1986, Volume: 12, Issue:6 Topics: Adult; Aged; Amiodarone; Disopyramide; Female; Flecainide; Humans; Hypotension, Orthostatic; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Quinidine; Sympathomimetics; Tocainide	1986
Metabolites of antiarrhythmic drugs: are they clinically important? Rational drug therapy, 1986, Volume: 20, Issue:5 Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Procainamide; Quinidine	1986
Chronic flecainide therapy selected by electrophysiology testing of intravenous flecainide. American heart journal, 1987, Volume: 114, Issue:1 Pt 1 Topics: Aged; Drug Administration Schedule; Electric Stimulation; Electrophysiology; Female; Flecainide; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Contraction; Procainamide; Tachycardia	1987
Aggravation of ventricular arrhythmia. A drug-induced complication. Drugs, 1985, Volume: 29 Suppl 4 Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
Haemodynamic effects of class I antiarrhythmic agents. Drugs, 1985, Volume: 29 Suppl 4 Topics: Anti-Arrhythmia Agents; Disopyramide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide	1985
[Anti-arrhythmia agents (I): Quinidine, procainamide, disopyramide, encainide, propafenone and flecainide]. Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:11 Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
Antiarrhythmic drug efficacy at electrophysiology testing: predictive effectiveness of procainamide and flecainide. American heart journal, 1986, Volume: 111, Issue:4 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Exercise Test; Female; Flecainide; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Piperidines; Procainamide; Prognosis	1986
Flecainide: long-term treatment using a reduced dosing schedule. The American journal of cardiology, 1985, Jan-01, Volume: 55, Issue:1 Topics: Anti-Arrhythmia Agents; Drug Administration Schedule; Electrocardiography; Female; Flecainide; Follow-Up Studies; Heart Ventricles; Humans; Male; Middle Aged; Piperidines; Procainamide; Tachycardia; Time Factors	1985
Antiarrhythmic drugs. British medical journal (Clinical research ed.), 1983, Apr-23, Volume: 286, Issue:6374 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil	1983
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
Sinusoidal ventricular tachycardia associated with flecainide acetate. Chest, 1984, Volume: 85, Issue:5 Topics: Aged; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrocardiography; Female; Flecainide; Heart Ventricles; Humans; Male; Middle Aged; Piperidines; Procainamide; Tachycardia	1984
Antiarrhythmic and electrophysiologic actions of flecainide in animal models. The American journal of cardiology, 1984, Feb-27, Volume: 53, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Electrophysiology; Flecainide; Heart Conduction System; In Vitro Techniques; Lidocaine; Piperidines; Procainamide; Quinidine; Rabbits	1984
Efficacy of type 1C antiarrhythmic agents for treatment of resistant atrial fibrillation. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:12 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Encainide; Female; Flecainide; Heart Rate; Humans; Male; Middle Aged; Procainamide; Propafenone; Quinidine; Recurrence; Retrospective Studies	1993
Effects of E-4031 on atrial fibrillation threshold in guinea pig atria: comparative study with class I antiarrhythmic drugs. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:4 Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Disopyramide; Electric Stimulation; Female; Flecainide; Guinea Pigs; Heart Atria; Heart Conduction System; In Vitro Techniques; Lidocaine; Male; Piperidines; Procainamide; Pyridines; Refractory Period, Electrophysiological	1994
Sustained atrial flutter around the tricuspid valve in pigs: differentiation of procainamide (class IA) from flecainide (class IC) and their rate-dependent effects. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:3 Topics: Animals; Atrial Flutter; Electrocardiography; Flecainide; Heart Conduction System; Male; Procainamide; Swine; Tricuspid Valve	1993
Use-dependent prolongation of ventricular tachycardia cycle length by type I antiarrhythmic drugs in humans. Circulation, 1993, Volume: 87, Issue:1 Topics: Adult; Aged; Anti-Arrhythmia Agents; Electrocardiography; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged; Procainamide; Tachycardia, Ventricular; Time Factors	1993
ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: insight into the mechanism of Brugada syndrome. Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:2 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Flecainide; Follow-Up Studies; Heart Rate; Humans; Lidocaine; Male; Middle Aged; Procainamide; Recurrence; Tachycardia, Paroxysmal; Tachycardia, Ventricular; Wolff-Parkinson-White Syndrome	1999
Comparison of cocaine and Na+ channel blockers on cardio-respiratory function in the rabbit. European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cocaine; Dopamine Uptake Inhibitors; Electrocardiography; Female; Flecainide; Heart; Heart Rate; Lidocaine; Male; Procainamide; Quinidine; Rabbits; Respiration; Sodium Channel Blockers	1999
Drug-drug interactions between antiarrhythmic drugs in chick embryos. Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Chick Embryo; Drug Interactions; Electrocardiography; Flecainide; Heart Rate; Procainamide; Propranolol	2004
Role of sodium and calcium channel block in unmasking the Brugada syndrome. Heart rhythm, 2004, Volume: 1, Issue:2 Topics: Ajmaline; Animals; Bundle-Branch Block; Calcium Channel Blockers; Dogs; Electrocardiography; Flecainide; Procainamide; Sodium Channel Blockers; Terfenadine; Verapamil	2004
Letter by Behr and Camm regarding article, "Induced Brugada-type electrocardiogram, a sign for imminent malignant arrhythmias". Circulation, 2008, Nov-18, Volume: 118, Issue:21 Topics: Adult; Age of Onset; Anesthetics; Antidepressive Agents, Tricyclic; Brugada Syndrome; Cocaine; Death, Sudden, Cardiac; Electrocardiography; Female; Fever; Flecainide; Heart Arrest; Humans; Male; Methadone; Middle Aged; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Procainamide; Propofol; Sodium Channel Blockers; Sodium Channels; Water-Electrolyte Imbalance	2008
Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia. Circulation. Arrhythmia and electrophysiology, 2011, Volume: 4, Issue:2 Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calsequestrin; Defibrillators, Implantable; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Countershock; Electrocardiography; Flecainide; Humans; Ion Channel Gating; Lidocaine; Male; Mice; Mice, Knockout; Mutation, Missense; Myocytes, Cardiac; Procainamide; Propafenone; Ryanodine Receptor Calcium Release Channel; Sodium Channel Blockers; Tachycardia, Ventricular; Time Factors; Young Adult	2011
Does a Brugada pattern ECG precipitated by excessive-dose flecainide provide a diagnosis of a Brugada syndrome patient and/or contraindicate its use? A case study. Circulation. Arrhythmia and electrophysiology, 2011, Volume: 4, Issue:4 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Brugada Syndrome; Catheter Ablation; Contraindications; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiologic Techniques, Cardiac; Flecainide; Humans; Male; Middle Aged; Procainamide; Treatment Outcome	2011
Positive Brugada challenge test in V1 R-V3 R as a predictor of malignant prognosis in Brugada patients. Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2013, Volume: 18, Issue:5 Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Female; Flecainide; Humans; Male; Predictive Value of Tests; Procainamide; Prognosis; Sensitivity and Specificity; Young Adult	2013
Arrhythmogenic drugs can amplify spatial heterogeneities in the electrical restitution in perfused guinea-pig heart: An evidence from assessments of monophasic action potential durations and JT intervals. PloS one, 2018, Volume: 13, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; In Vitro Techniques; Perfusion; Phenethylamines; Procainamide; Quinidine; Sulfonamides	2018
Flecainide Versus Procainamide in Electrophysiological Study in Patients With Syncope and Wide QRS Duration. JACC. Clinical electrophysiology, 2019, Volume: 5, Issue:2 Topics: Aged; Aged, 80 and over; Bundle-Branch Block; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Heart Conduction System; Humans; Male; Middle Aged; Procainamide; Syncope	2019
Flecainide to Unmask Infranodal Disease: A Better Sieve? JACC. Clinical electrophysiology, 2019, Volume: 5, Issue:2 Topics: Bundle-Branch Block; Flecainide; Humans; Procainamide; Syncope	2019
Antiarrhythmic drug effects on premature beats are partly determined by prior cardiac activation frequency in perfused guinea-pig heart. Experimental physiology, 2020, Volume: 105, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Phenethylamines; Procainamide; Quinidine; Sulfonamides	2020
Electrocardiographic marker of the cardiac action potential triangulation induced by antiarrhythmic drugs in perfused guinea-pig heart. Experimental physiology, 2022, Volume: 107, Issue:8 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Flecainide; Guinea Pigs; Pericardium; Procainamide; Quinidine	2022
T-Peak to T-End Interval for Prediction of Positive Response to Ajmaline Challenge Test in Suspected Brugada Syndrome Patients. Medical sciences (Basel, Switzerland), 2022, 12-19, Volume: 10, Issue:4 Topics: Ajmaline; Brugada Syndrome; Flecainide; Humans; Procainamide; Sodium Channel Blockers	2022