flecainide and lidocaine

flecainide has been researched along with lidocaine in 134 studies

Research

Studies (134)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (30.60)	18.7374
1990's	45 (33.58)	18.2507
2000's	30 (22.39)	29.6817
2010's	17 (12.69)	24.3611
2020's	1 (0.75)	2.80

Authors

Authors	Studies
Argentieri, TM; Gomez, RP; Lind, JM; Morgan, TK; Nickisch, K; Phillips, GB; Sullivan, ME; Wohl, RA	1
Barcelon-Yang, C; Black, LA; Brown, BS; Matier, WL; Quon, CY; Stampfli, HF; Stout, DM	1
Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Abraham, S; Barrett, TD; Beatch, GN; Clohs, L; Dong, Y; Fedida, D; Jung, GL; Liu, Y; Lynn, L; Plouvier, B; Sheng, T; Walker, MJ; Wall, RA; Wang, WQ; Zhu, JJ; Zolotoy, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Sen, S; Sinha, N	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Arita, M; Kiyosue, T; Sato, T; Wu, B	1
Kato, R; Koide, M; Miyahara, T; Sotobata, I; Toyama, J; Ukai, M; Yasui, S; Yokota, M	1
Hsieh, MZ; Penz, W; Pugsley, M; Walker, MJ	1
Ikeda, N; Kamiya, K	1
Rabkin, SW	1
Hashimoto, H; Katoh, H; Nakashima, M	1
Campbell, TJ; Pallandi, R; Wyse, KR	1
Asayama, J; Inoue, D; Inoue, M; Katsume, H; Nakagawa, M; Shirayama, T; Tatsumi, T; Yamahara, Y	1
Fukami, M; Hashimoto, T; Itoh, Y; Koike, H; Kumakura, S; Miyake, S; Mizuno, H; Shiga, H; Shimoji, Y; Yorikane, R	1
Akaike, N; Inomata, N; Ishihara, T	1
Duker, BG	1
Cheymol, G; Chézalviel, F; Davy, JM; Engel, F; Ertzbischoff, O; Lainée, P; Motté, G; Penin, E; Poirier, JM; Weissenburger, J	1
Camm, AJ; Garratt, CJ; Griffith, MJ; Linker, NJ; Ward, DE	1
Desai, DM; Gal, J; Meyer-Lehnert, S	1
Keefe, DL; Miura, D; Somberg, JC	1
Grauer, K; Gums, J; Skluth, H	1
Hoffman, BF; Spinelli, W	1
Bleske, BE; Chow, MS; Fisher, J; Kluger, J	1
Somberg, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Roy, D	1
Engel, T; Kelliher, GJ; Kowey, P; Wetstein, L	1
Echt, DS; Roden, DM; Woosley, RL	1
Morganroth, J; Nestico, PF	2
Huang, SK; Marcus, FI	1
Light, RT; Onrot, J; Robertson, D; Robertson, RM; Tantengco, MV	1
Kates, RE	1
Horowitz, LN; Morganroth, J	1
Frais, MA; Hafizullah, M; Jackson, NC; Kalra, PA; Reynolds, GW; Silke, B; Taylor, SH; Verma, SP	1
Bauman, JL; Gallastegui, J; Hariman, RJ; Tanenbaum, SR	1
Hammill, SC; Kreeger, RW	1
Baedeker, W; Barthel, P; Blömer, H; Goedel-Meinen, L; Hofmann, M; Schmidt, G	1
Fingerhood, M; Keefe, D; Maza, S; Miura, D; Somberg, JC; Wynn, J	1
Collignon, P; Legrand, V	1
Podrid, PJ	1
Sanna, GP	1
Hillis, WS; Whiting, B	1
Somberg, JC	1
Duff, HJ; Oates, JA; Roden, DM; Woosley, RL	1
Block, PJ; Winkle, RA	1
Pottage, A	1
Harrison, DC; Mead, RH	1
McDevitt, DG	1
Hugenholtz, PG; Serruys, PW; Vanhaleweyk, G	1
Camm, AJ	1
Orning, OM	1
Hellestrand, KJ	1
Luck, JC; Mann, DE; Pratt, CM; Wyndham, CR	1
Banitt, EH; Kvam, DC; Schmid, JR	1
Bexton, RS; Burnett, PJ; Camm, AJ; Debbas, NM; Hellestrand, KJ; Milne, JR	1
Atallah, G; Kirkorian, G; Moleur, P; Touboul, P	1
Bender, F; Gülker, H; Heuer, H; Hübner, G; Kristek, J; Schindelhauer, F; Thale, J	1
Haruno, A; Hashimoto, K	1
Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Sakai, R; Shirayama, T	1
Chi, L; Fagbemi, SO; Lucchesi, BR	1
Lee, JK; Nonokawa, M; Sugiyama, T; Takanaka, C; Yame, S	1
Gutiérrez-Larraya, F; Jabón, A	1
Barchi, RL; Davison, K; Dugrenier, N; Estep, K; Ezrin, AM; Josef, K; Kallen, RG; Krafte, DS; Silver, PJ	1
Higuchi, M; Itomine, T; Matsuzaki, T; Nakasone, J; Noguchi, K; Ojiri, Y; Sakanashi, M; Shiroma, N	1
Hayashi, Y; Kamibayashi, T; Kawabata, K; Sumikawa, K; Takada, K; Yamatodani, A; Yoshiya, I	1
Liu, JX; Ohtsuka, Y; Sakai, Y; Takeo, S; Tanonaka, K	1
Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Omori, I; Sakai, R; Yamahara, Y	1
Greenberg, RM; Greenspon, AJ; Kidwell, GA; Volosin, KJ	1
Akaike, N; Inomata, N; Ishihara, T; Ohno, T	1
Barrett, TD; Hayes, ES; Walker, MJ	1
Hatakeyama, N; Inoko, M; Kihara, Y; Momose, Y; Sasayama, S	1
Catterall, WA; McPhee, JC; Ragsdale, DS; Scheuer, T	1
Ito, K; Koike, H; Nagafuchi, K; Taga, A; Yorikane, R	1
Adgey, AA; Allen, JD; Devine, AB; Stewart, AJ	1
Aupetit, JF; Faucon, G; Loufoua-Moundanga, J; Timour, Q	1
Casanova, JM; De Micheli, A; Iturralde, P; Medrano, GA	1
Kondo, T; Kubota, I; Tachibana, H; Tomoike, H; Yamaki, M	1
Fernández del Pozo, B; Fernández, C; Pérez-Vizcaíno, F; Tamargo, J; Zaragozá, F	1
Annoura, M; Arakawa, K; Ideishi, M; Kumagai, K; Matsuo, K	1
Imagawa, N; Sato, S	1
Ito, H; Nakamura, W; Segawa, K; Tanaka, S; Yoshimoto, N	1
Kubota, I; Tachibana, H; Tomoike, H; Watanabe, T; Yamaki, M	2
Fujiki, A; Hayashi, H; Inoue, H; Mizumaki, K; Nagasawa, H; Usui, M	1
Kubota, I; Tachibana, H; Tomoike, H; Watanabe, T; Yamaki, M; Yamauchi, S	2
Erzouki, HK; Goldberg, SR; Schindler, CW	1
Benhorin, J; Goldmit, M; Kass, RS; Kerem, B; Medina, A; Taub, R; Windman, I	1
Abriel, H; Benhorin, J; Kass, RS; Kerem, B; Wehrens, XH	1
Carboni, M; Chandra, R; Grant, AO; Keller, C; Starmer, CF	1
Kawano, Y; Mineda, Y; Nakata, Y; Nakazato, K; Nakazato, Y; Sekita, G; Sumiyoshi, M; Tokano, T; Yamashita, H; Yasuda, M	1
Azegami, K; Hiejima, K; Hirao, K; Horikawa, T; Kawabata, M; Motokawa, K; Suzuki, F; Suzuki, K	1
Curtis, MJ; Farkas, A	1
Hancox, JC; Paul, AA; Witchel, HJ	1
Imai, H; Matoba, Y; Nakagawa, M; Shiraishi, H; Shirayama, T; Yoshida, S	1
Hara, H; Ikeda-Murakami, K; Inuo, K; Izumi, T; Kojima, J; Niwano, S; Saito, J; Yoshida, T	2
Blaker, PA; Davies, M; Hall, SM; Kapoor, R; Smith, KJ	1
Atkins, J; Kass, RS; Liu, H	1
Katoh, T; Ono, T; Sutovsky, I; Takano, T; Takayama, H	1
Kubota, I; Nagai, S; Takeishi, Y	1
Dohi, S; Iida, H; Oda, A; Osawa, Y; Tanahashi, S	1
Esato, M; Inoue, N; Kakugawa, H; Kametani, R; Kanemoto, M; Matsuzaki, M; Sawa, A; Shimizu, A; Ueyama, T; Yamagata, T; Yoshiga, Y	1
Carr, DB; Challapalli, V; Lau, J; McNicol, ED; Tremont-Lukats, IW	1
Chen, YW; Cheng, KI; Chu, CC; Chu, KS; Huang, KL; Tzeng, JI; Wang, JJ	1
Furukawa, T; Hachiya, H; Higuchi, K; Hirao, K; Isobe, M; Kawabata, M; Okada, H; Sasaki, T	1
Aoyama, H; Enomoto, M; Hirayama, A; Imai, S; Kushiro, T; Saito, F; Takase, H; Yagi, H; Yamaji, S; Yokoyama, K	1
Gallacher, DJ; Lu, HR; Rohrbacher, J; Van Ammel, K; Vlaminckx, E; Yan, GX	1
Bruno, C; Conte Camerino, D; Costanza, T; Desaphy, JF; Dipalma, A; Franchini, C; George, A; Lentini, G	1
Faggioni, M; Hasdemir, C; Hwang, HS; Knollmann, BC; Laver, D; Mehra, D; Turhan, K; Yin, H	1
Bankston, JR; Bayer, JD; Christini, DJ; Clancy, CE; Jeng, MT; Kang, C; Kass, RS; Moreno, JD; Ripplinger, CM; Trayanova, NA; Wang, L; Yang, PC; Zhu, ZI	1
Favier, JC; Landy, C; Plancade, D; Raynaud, L; Schaeffer, E	1
Osadchii, OE	1
Aiba, T; Ishibashi, K; Kamakura, S; Kamakura, T; Kimura, T; Kusano, K; Makiyama, T; Miyamoto, K; Nakajima, I; Noda, T; Ogawa, H; Okamura, H; Shimizu, W; Takaki, H; Wada, M; Yasuda, S	1
Akin, I; Behnes, M; Borggrefe, M; Dworacek, J; El-Battrawy, I; Lang, S; Liebe, V; Meister, S; Patocskai, B; Rudic, B; Tiburcy, M; Tülümen, E; Utikal, J; Wieland, T; Yücel, G; Zhao, Z; Zhou, XB; Zimmermann, WH	1
Kleinlogel, S; Streit, J	1
Clancy, CE; DeMarco, KR; Nguyen, PT; Vorobyov, I; Yarov-Yarovoy, V	1
Andrews, LM; Koch, BCP; van der Nagel, BCH; van Domburg, B	1
Sijm, DTHM; Tukker, AM; van Kleef, RGDM; Vrolijk, MF; Westerink, RHS	1

Reviews

23 review(s) available for flecainide and lidocaine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
The treatment of ventricular rhythm disturbances. American heart journal, 1986, Volume: 111, Issue:6 Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Disopyramide; Electric Countershock; Electric Stimulation; Electrocardiography; Exercise Test; Flecainide; Heart Ventricles; Humans; Lidocaine; Phenytoin; Piperidines; Procainamide; Quinidine; Risk; Tachycardia; Tocainide; United States; Ventricular Fibrillation; Verapamil	1986
Ventricular arrhythmias. An assessment of newer therapeutic agents. Postgraduate medicine, 1989, May-01, Volume: 85, Issue:6 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Flecainide; Humans; Lidocaine; Mexiletine; Tocainide; United States	1989
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Antiarrhythmic drugs. Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2 Topics: Action Potentials; Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium Channel Blockers; Cell Membrane; Disopyramide; Electrophysiology; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide	1986
Clinical pharmacology of antiarrhythmic agents. Cardiovascular clinics, 1985, Volume: 16, Issue:1 Topics: Adrenergic beta-Antagonists; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Calcium Channel Blockers; Electrophysiology; Encainide; Flecainide; Heart Conduction System; Humans; Lidocaine; Moricizine; Phenothiazines; Piperidines; Quaternary Ammonium Compounds; Sotalol; Tocainide	1985
Effects of congestive heart failure on the pharmacokinetics and pharmacodynamics of antiarrhythmic agents. The American journal of cardiology, 1986, Jan-31, Volume: 57, Issue:3 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Digitalis; Disopyramide; Drug Interactions; Encainide; Flecainide; Half-Life; Heart Failure; Hemodynamics; Humans; Kidney; Kinetics; Lidocaine; Liver; Piperidines; Plants, Medicinal; Plants, Toxic; Potassium; Procainamide; Quinidine; Regional Blood Flow; Tocainide	1986
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment. Cardiology clinics, 1986, Volume: 4, Issue:2 Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil	1986
Antiarrhythmic drug therapy of ventricular arrhythmias. Current problems in cardiology, 1986, Volume: 11, Issue:4 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Tosylate; Disopyramide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Sotalol; Tocainide; Verapamil	1986
Antiarrhythmic agents for chronic ventricular arrhythmias. Comprehensive therapy, 1987, Volume: 13, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide	1987
New antiarrhythmic drugs: tocainide, mexiletine, flecainide, encainide, and amiodarone. Mayo Clinic proceedings, 1987, Volume: 62, Issue:11 Topics: Administration, Oral; Amiodarone; Anilides; Anti-Arrhythmia Agents; Drug Interactions; Encainide; Flecainide; Heart Conduction System; Humans; Lidocaine; Mexiletine; Tachycardia; Tocainide	1987
Antiarrhythmic drug therapy (Part 2). Benefits and hazards. Chest, 1985, Volume: 88, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1985
Hemodynamic effects of antiarrhythmic drugs. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide	1983
Clinical profiles of newer class I antiarrhythmic agents--tocainide, mexiletine, encainide, flecainide and lorcainide. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Administration, Oral; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Injections, Intravenous; Kinetics; Lidocaine; Mexiletine; Piperidines; Tocainide	1983
Therapy with investigational antiarrhythmic drugs. The Medical clinics of North America, 1984, Volume: 68, Issue:5 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Tocainide	1984
Haemodynamic effects of encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Piperidines; Tocainide	1984
Cardiac electrophysiology of four new antiarrhythmic drugs--encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Action Potentials; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrocardiography; Electrophysiology; Encainide; Flecainide; Heart; Heart Conduction System; Humans; Lidocaine; Piperidines; Sinoatrial Node; Tocainide	1984
Comparison of the efficacy of newly developed antiarrhythmic drugs in the treatment of ventricular tachyarrhythmias. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Coronary Disease; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Piperidines; Tachycardia; Tocainide; Ventricular Fibrillation	1984
Investigational antiarrhythmic drugs for the treatment of ventricular rhythm disturbances. Cardiology clinics, 1984, Volume: 2, Issue:1 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Tocainide	1984
[New antiarrythmic drugs: mexiletine, tocainide, lorcainide, encainide, flecainide, propafenone, cipralan, sotalol]. Annales de cardiologie et d'angeiologie, 1982, Volume: 31, Issue:7 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Sotalol; Tocainide	1982
[Tachycardias: considerations in childhood in the 90s]. Anales espanoles de pediatria, 1993, Volume: 39, Issue:6 Topics: Adenosine; Adolescent; Adult; Amiodarone; Atrial Flutter; Child; Child, Preschool; Electrocardiography; Ergometry; Flecainide; Heart; Heart Ventricles; Humans; Infant; Infant, Newborn; Lidocaine; Middle Aged; Propafenone; Sotalol; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Tachycardia, Ventricular	1993
Systemic administration of local anesthetic agents to relieve neuropathic pain. The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4 Topics: Administration, Oral; Anesthetics, Intravenous; Anesthetics, Local; Flecainide; Humans; Lidocaine; Mexiletine; Nervous System Diseases; Pain; Randomized Controlled Trials as Topic; Tocainide	2005

Trials

8 trial(s) available for flecainide and lidocaine

Article	Year
Relative efficacy and safety of intravenous drugs for termination of sustained ventricular tachycardia. Lancet (London, England), 1990, Sep-15, Volume: 336, Issue:8716 Topics: Adenosine; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Disopyramide; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Flecainide; Humans; Hypotension; Injections, Intravenous; Lidocaine; Middle Aged; Recurrence; Sotalol; Tachycardia	1990
Comparative haemodynamic effects of intravenous lignocaine, disopyramide and flecainide in uncomplicated acute myocardial infarction. British journal of clinical pharmacology, 1986, Volume: 22, Issue:6 Topics: Adult; Aged; Disopyramide; Flecainide; Hemodynamics; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Myocardial Infarction; Prospective Studies	1986
[Effect of class I anti-arrhythmia agents on the signal-averaged ECG]. Herz, 1988, Volume: 13, Issue:3 Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Clinical Trials as Topic; Coronary Disease; Disopyramide; Electrocardiography; Female; Flecainide; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Random Allocation; Signal Processing, Computer-Assisted; Tachycardia; Tocainide	1988
Selection of an antiarrhythmic drug for a sudden-death-prevention trial. American heart journal, 1982, Volume: 103, Issue:4 Pt 2 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Encainide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Moricizine; Morpholines; Phenothiazines; Piperidines; Tocainide; Verapamil	1982
Mechanism of antiarrhythmic effects of class Ic drugs in paroxysmal atrial fibrillation in man. Cardiology, 1998, Volume: 89, Issue:2 Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Electrocardiography; Electrophysiology; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged	1998
Bepridil prevents paroxysmal atrial fibrillation by a class III antiarrhythmic drug effect. Pacing and clinical electrophysiology : PACE, 2003, Volume: 26, Issue:1P2 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Electrocardiography; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged	2003
Low-dose flecainide infusion followed by oral pilsicainide is highly effective and safe for paroxysmal atrial fibrillation. Cardiovascular drugs and therapy, 2003, Volume: 17, Issue:1 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Therapy, Combination; Female; Flecainide; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged	2003
Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus rhythm. Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:5 Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Natriuretic Factor; Bepridil; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Follow-Up Studies; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Natriuretic Peptide, Brain; Sinoatrial Node; Treatment Outcome	2008

Other Studies

103 other study(ies) available for flecainide and lidocaine

Article	Year
Synthesis and cardiac electrophysiological activity of aryl-substituted derivatives of the class III antiarrhythmic agent sematilide. Potential class I/III agents. Journal of medicinal chemistry, 1990, Volume: 33, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chemical Phenomena; Chemistry; Dogs; Drug Design; Electrophysiology; Guinea Pigs; In Vitro Techniques; Ouabain; Procainamide; Purkinje Fibers; Structure-Activity Relationship	1990
Ester derivatives of 2,6-bis(1-pyrrolidinylmethyl)-4-benzamidophenol as short-acting antiarrhythmic agents. 1. Journal of medicinal chemistry, 1989, Volume: 32, Issue:8 Topics: Animals; Anti-Arrhythmia Agents; Dogs; Esters; Guinea Pigs; Humans; Male; Pyrrolidines	1989
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents. Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship	1993
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Synthesis and biological studies of novel 2-aminoalkylethers as potential antiarrhythmic agents for the conversion of atrial fibrillation. Journal of medicinal chemistry, 2007, Jun-14, Volume: 50, Issue:12 Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Biological Availability; Cell Line; Crystallography, X-Ray; Cyclohexanes; Dogs; Electric Stimulation; Ethers; Female; Humans; Male; Mice; Molecular Structure; Myocardial Ischemia; Patch-Clamp Techniques; Potassium Channels, Voltage-Gated; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium Channels; Stereoisomerism; Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs. Cardiovascular research, 1992, Volume: 26, Issue:11 Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Dinitrophenols; Disopyramide; Flecainide; Glyburide; Guinea Pigs; Heart Ventricles; Imidazoles; Lidocaine; Mexiletine; Myocardium; Piperidines; Potassium; Procainamide; Pyridines	1992
[Pharmacokinetics and pharmacodynamics of class I antiarrhythmic agents after a single oral administration]. Japanese circulation journal, 1992, Volume: 56 Suppl 5 Topics: Administration, Oral; Anti-Arrhythmia Agents; Aprindine; Flecainide; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone	1992
A new ECG measure (RSh) for detecting possible sodium channel blockade in vivo in rats. Journal of pharmacological and toxicological methods, 1992, Volume: 27, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Electrocardiography; Flecainide; Heart Rate; Lidocaine; Male; Quinidine; Rats; Rats, Inbred Strains; Sodium; Sodium Channels	1992
[Estimation of depressant effects of class I antiarrhythmic drugs on intraventricular conduction--rate-dependent effects on QRS duration]. Japanese circulation journal, 1992, Volume: 56 Suppl 5 Topics: Anti-Arrhythmia Agents; Aprindine; Depression, Chemical; Disopyramide; Electrocardiography; Flecainide; Heart Conduction System; Heart Rate; Humans; Lidocaine; Mexiletine; Sodium Channels; Ventricular Function	1992
Effect of antiarrhythmic drugs on choline uptake in cardiac cells in culture. Cardiovascular research, 1992, Volume: 26, Issue:1 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Chick Embryo; Choline; Dose-Response Relationship, Drug; Encainide; Flecainide; Heart; Lidocaine; Myocardium; Propafenone; Tocainide	1992
Effects of flecainide on ventricular arrhythmias, abnormal automaticity and activation in a canine model of myocardial infarction. Journal of pharmacobio-dynamics, 1992, Volume: 15, Issue:5 Topics: Animals; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Electrocardiography; Flecainide; Heart Rate; Heart Ventricles; Injections, Intravenous; Lidocaine; Myocardial Infarction	1992
Differential effects on action potential duration of class IA, B and C antiarrhythmic drugs: modulation by stimulation rate and extracellular K+ concentration. Clinical and experimental pharmacology & physiology, 1991, Volume: 18, Issue:8 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Flecainide; Heart Rate; In Vitro Techniques; Lidocaine; Potassium Channels; Purkinje Fibers; Sodium Channels	1991
Electrophysiological effects of sodium channel blockers on guinea pig left atrium. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Aprindine; Atrial Function; Atrial Function, Left; Diastole; Disopyramide; Electrophysiology; Female; Flecainide; Guinea Pigs; Heart; Heart Atria; Kinetics; Lidocaine; Male; Sodium Channels	1991
Antiarrhythmic and cardiovascular profiles of the fused indole compound (3aR,12R,12aR,12bS)-12-amino-2,3,3a,4,11,12,12a,12b-octahydro-10-hydrox yisoquino [2,1,8-lma]carbazol-5(1H)-one hydrochloride 1.5 hydrate. Arzneimittel-Forschung, 1991, Volume: 41, Issue:11 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbazoles; Chloroform; Disopyramide; Dogs; Female; Flecainide; Heart; Heart Conduction System; Hemodynamics; Isoquinolines; Lidocaine; Male; Mexiletine; Mice; Mice, Inbred ICR; Myocardial Contraction; Ouabain	1991
Mechanisms of the anticholinergic effect of SUN 1165 in comparison with flecainide, disopyramide and quinidine in single atrial myocytes isolated from guinea-pig. British journal of pharmacology, 1991, Volume: 104, Issue:4 Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Flecainide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Myocardium; Parasympatholytics; Potassium Channels; Quinidine; Receptors, Cholinergic	1991
Frequency dependent effects of tocainide, quinidine, and flecainide on conduction as reflected in the rise time of the monophasic action potential in the isolated guinea pig heart. Cardiovascular research, 1991, Volume: 25, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Flecainide; Guinea Pigs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Kinetics; Lidocaine; Quinidine; Tocainide	1991
Arrhythmogenic activities of antiarrhythmic drugs in conscious hypokalemic dogs with atrioventricular block: comparison between quinidine, lidocaine, flecainide, propranolol and sotalol. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Bradycardia; Consciousness; Diuretics; Dogs; Electrocardiography, Ambulatory; Electrolytes; Electrophysiology; Female; Flecainide; Heart Block; Hypocalcemia; Lidocaine; Male; Propranolol; Quinidine; Sotalol	1991
Reversed-phase LC resolutions of chiral antiarrhythmic agents via derivatization with homochiral isothiocyanates. Chirality, 1990, Volume: 2, Issue:1 Topics: Anti-Arrhythmia Agents; Chromatography, Liquid; Flecainide; Humans; Indicators and Reagents; Lidocaine; Male; Mexiletine; Propafenone; Thiocyanates; Tocainide	1990
Mechanisms of termination of reentrant atrial arrhythmias by class I and class III antiarrhythmic agents. Circulation research, 1989, Volume: 65, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Electrocardiography; Flecainide; Heart Conduction System; Heart Rate; Lidocaine; Piperidines; Propafenone; Sotalol	1989
Acute effects of combination of IB and IC antiarrhythmics for the treatment of ventricular tachycardia. Journal of clinical pharmacology, 1989, Volume: 29, Issue:11 Topics: Anilides; Anti-Arrhythmia Agents; Blood Pressure; Drug Therapy, Combination; Electric Stimulation; Electrocardiography; Encainide; Flecainide; Heart Rate; Hemodynamics; Humans; Lidocaine; Male; Middle Aged; Refractory Period, Electrophysiological; Tachycardia	1989
Orthostatic hypotension: clinical spectrum and approach to treatment. Comprehensive therapy, 1986, Volume: 12, Issue:6 Topics: Adult; Aged; Amiodarone; Disopyramide; Female; Flecainide; Humans; Hypotension, Orthostatic; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Quinidine; Sympathomimetics; Tocainide	1986
Metabolites of antiarrhythmic drugs: are they clinically important? Rational drug therapy, 1986, Volume: 20, Issue:5 Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Procainamide; Quinidine	1986
Second generation antiarrhythmic agents: have we reached antiarrhythmic Nirvana? Journal of the American College of Cardiology, 1987, Volume: 9, Issue:2 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Tocainide	1987
Drug therapy: flecainide and tocainide. The New England journal of medicine, 1987, Feb-05, Volume: 316, Issue:6 Topics: Aged; Anti-Arrhythmia Agents; Flecainide; Humans; Lidocaine; Tocainide	1987
Flecainide-induced sustained ventricular tachycardia successfully treated with lidocaine. Chest, 1987, Volume: 92, Issue:3 Topics: Aged; Electrocardiography; Flecainide; Humans; Lidocaine; Male; Tachycardia	1987
Refractory ventricular tachycardia with flecainide. American heart journal, 1986, Volume: 112, Issue:1 Topics: Aged; Anti-Arrhythmia Agents; Flecainide; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Piperidines; Tachycardia	1986
Haemodynamic effects of class I antiarrhythmic agents. Drugs, 1985, Volume: 29 Suppl 4 Topics: Anti-Arrhythmia Agents; Disopyramide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide	1985
New drugs in the management of ventricular arrhythmias. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Drug Interactions; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1984
Antiarrhythmic drugs. British medical journal (Clinical research ed.), 1983, Apr-23, Volume: 286, Issue:6374 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil	1983
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
The clinical pharmacology of lidocaine congeners--review of encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Benzeneacetamides; Encainide; Flecainide; Humans; Kinetics; Lidocaine; Piperidines; Tocainide	1984
The use of tocainide, encainide, lorcainide and flecainide for supraventricular arrhythmias. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Benzeneacetamides; Encainide; Flecainide; Heart Atria; Humans; Lidocaine; Piperidines; Tachycardia; Tocainide; Wolff-Parkinson-White Syndrome	1984
Antiarrhythmic and electrophysiologic actions of flecainide in animal models. The American journal of cardiology, 1984, Feb-27, Volume: 53, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Electrophysiology; Flecainide; Heart Conduction System; In Vitro Techniques; Lidocaine; Piperidines; Procainamide; Quinidine; Rabbits	1984
Class 1 antiarrhythmic drugs--characteristic electrocardiographic differences when assessed by atrial and ventricular pacing. European heart journal, 1984, Volume: 5, Issue:2 Topics: Action Potentials; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Coronary Disease; Disopyramide; Electrocardiography; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged; Piperidines	1984
[Anti-arrhythmia effect of flecainide in acute myocardial infarct in comparison with lidocaine]. Die Medizinische Welt, 1981, Jul-17, Volume: 32, Issue:29 Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Dogs; Flecainide; Lidocaine; Myocardial Infarction; Piperidines	1981
Antiarrhythmic effects of bisaramil on triggered arrhythmias produced by intracoronary injection of digitalis and adrenaline in the dog. Japanese journal of pharmacology, 1995, Volume: 68, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bridged Bicyclo Compounds, Heterocyclic; Chlorobenzenes; Digitalis Glycosides; Disease Models, Animal; Disopyramide; Dogs; Epinephrine; Female; Flecainide; Injections, Intra-Arterial; Lidocaine; Male; Ouabain; Verapamil	1995
Effects of E-4031 on atrial fibrillation threshold in guinea pig atria: comparative study with class I antiarrhythmic drugs. Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:4 Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Disopyramide; Electric Stimulation; Female; Flecainide; Guinea Pigs; Heart Atria; Heart Conduction System; In Vitro Techniques; Lidocaine; Male; Piperidines; Procainamide; Pyridines; Refractory Period, Electrophysiological	1994
Antifibrillatory and profibrillatory actions of selected class I antiarrhythmic agents. Journal of cardiovascular pharmacology, 1993, Volume: 21, Issue:5 Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Blood Gas Analysis; Electrophysiology; Flecainide; Glyburide; Guanidines; In Vitro Techniques; Lidocaine; Male; Myocardial Contraction; Pinacidil; Potassium Channels; Quinidine; Rabbits; Refractory Period, Electrophysiological; Vasodilator Agents	1993
Frequency dependent effects of class I antiarrhythmic agents studied in patients with implanted pacemakers. Pacing and clinical electrophysiology : PACE, 1994, Volume: 17, Issue:11 Pt 2 Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Cross-Over Studies; Disopyramide; Electrocardiography; Flecainide; Humans; Lidocaine; Pacemaker, Artificial	1994
Pharmacological modulation of human cardiac Na+ channels. European journal of pharmacology, 1994, Feb-15, Volume: 266, Issue:3 Topics: Animals; Azetidines; Cardiotonic Agents; Electrophysiology; Female; Flecainide; Humans; Lidocaine; Mercaptopurine; Myocardium; Oocytes; Piperazines; Quinidine; RNA, Complementary; Sodium Channels; Tetrodotoxin; Transcription, Genetic; Xenopus laevis	1994
Effects of pilsicainide on systemic hemodynamics and cardiac function of anesthetized dogs. Cardioscience, 1993, Volume: 4, Issue:4 Topics: Anesthesia, Intravenous; Animals; Anti-Arrhythmia Agents; Depression, Chemical; Dogs; Female; Flecainide; Heart; Hemodynamics; Lidocaine; Male; Myocardial Contraction; Propafenone	1993
Comparative efficacy of antiarrhythmic agents in preventing halothane-epinephrine arrhythmias in rats. Anesthesiology, 1993, Volume: 79, Issue:3 Topics: Amiodarone; Anesthesia, Inhalation; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Epinephrine; Flecainide; Halothane; Isoflurane; Lidocaine; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Verapamil	1993
Improvement of ischemia/reperfusion-induced contractile dysfunction of perfused hearts by class Ic antiarrhythmic agents. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 266, Issue:3 Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Creatine Kinase; Flecainide; Heart; Lidocaine; Male; Metals; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Perfusion; Rats; Rats, Wistar; Ventricular Function, Left	1993
Effects of pilsicainide on the atrial fibrillation threshold in guinea pig atria. A comparative study with disopyramide, lidocaine and flecainide. Japanese heart journal, 1993, Volume: 34, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Electrophysiology; Female; Flecainide; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Male	1993
Use-dependent prolongation of ventricular tachycardia cycle length by type I antiarrhythmic drugs in humans. Circulation, 1993, Volume: 87, Issue:1 Topics: Adult; Aged; Anti-Arrhythmia Agents; Electrocardiography; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged; Procainamide; Tachycardia, Ventricular; Time Factors	1993
Antiarrhythmic agents act differently on the activation phase of the ACh-response in guinea-pig atrial myocytes. British journal of pharmacology, 1993, Volume: 108, Issue:1 Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Disopyramide; Electric Conductivity; Flecainide; Guinea Pigs; Lidocaine; Male; Myocardium; Potassium; Potassium Channels; Propafenone	1993
Lack of selectivity for ventricular and ischaemic tissue limits the antiarrhythmic actions of lidocaine, quinidine and flecainide against ischaemia-induced arrhythmias. European journal of pharmacology, 1995, Oct-24, Volume: 285, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Flecainide; Heart; Heart Rate; Heart Ventricles; In Vitro Techniques; Lidocaine; Male; Myocardial Ischemia; Quinidine; Rats; Rats, Sprague-Dawley	1995
Mechanisms of negative inotropic effects of class Ic antiarrhythmic agents: comparative study of the effects of flecainide and pilsicainide on intracellular calcium handling in dog ventricular myocardium. Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channels; Depression, Chemical; Dogs; Dose-Response Relationship, Drug; Flecainide; Heart Ventricles; Lidocaine; Myocardial Contraction; Myocardium; Sarcolemma	1996
Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels. Proceedings of the National Academy of Sciences of the United States of America, 1996, Aug-20, Volume: 93, Issue:17 Topics: Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Binding Sites; Dose-Response Relationship, Drug; Flecainide; Ion Channel Gating; Lidocaine; Mutagenesis, Site-Directed; Mutation; Phenytoin; Quinidine; Rats; Recombinant Proteins; Sodium Channels; Structure-Activity Relationship	1996
Possible involvement of altered Na+ -Ca2+ exchange in negative inotropic effects of class I antiarrhythmic drugs on rabbit and rat ventricles. Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channels; Carbazoles; Depression, Chemical; Dose-Response Relationship, Drug; Flecainide; In Vitro Techniques; Isoquinolines; Lidocaine; Male; Myocardial Contraction; Rabbits; Rats; Rats, Wistar; Ryanodine; Sodium; Sodium Channels	1996
Effects of blockade of fast and slow inward current channels on ventricular fibrillation in the pig heart. Heart (British Cardiac Society), 1996, Volume: 76, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Disopyramide; Electrocardiography; Flecainide; Lidocaine; Mexiletine; Models, Biological; Sodium-Potassium-Exchanging ATPase; Swine; Ventricular Fibrillation; Verapamil	1996
Ischaemia-induced loss or reversal of the effects of the class I antiarrhythmic drugs on vulnerability to fibrillation. British journal of pharmacology, 1997, Volume: 120, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Vessels; Disopyramide; Electric Stimulation; Electrophysiology; Female; Flecainide; Heart Conduction System; In Vitro Techniques; Injections, Intravenous; Lidocaine; Male; Myocardial Ischemia; Swine; Ventricular Fibrillation	1997
Effects of verapamil in ventricular tachycardias. An experimental and clinical study. Acta cardiologica, 1997, Volume: 52, Issue:1 Topics: Aconitine; Adult; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Electrocardiography; Flecainide; Humans; Lidocaine; Tachycardia, Ventricular; Verapamil	1997
Electrophysiologic effects of sodium channel blockade on anisotropic conduction and conduction block in canine myocardium: preferential slowing of longitudinal conduction by flecainide versus disopyramide or lidocaine. Journal of the American College of Cardiology, 1997, Volume: 29, Issue:7 Topics: Animals; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Disopyramide; Dogs; Electric Conductivity; Electrophysiology; Flecainide; Heart Conduction System; Heart Ventricles; Lidocaine; Sodium Channels; Ventricular Fibrillation	1997
Effects of several class I antiarrhythmic drugs on isolated rat aortic vascular smooth muscle. General pharmacology, 1997, Volume: 29, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Aorta; Desipramine; Disopyramide; Flecainide; Imipramine; In Vitro Techniques; Lidocaine; Male; Mexiletine; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Quinidine; Rats; Rats, Sprague-Dawley	1997
Effects of lidocaine and mexiletine on defibrillation energy requirements in animals treated with flecainide. Resuscitation, 1998, Volume: 36, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Dogs; Electric Countershock; Flecainide; Lidocaine; Mexiletine; Ventricular Fibrillation	1998
Class IC antiarrhythmic drugs, flecainide and pilsicainide, produce ST segment elevation simulating inferior myocardial ischemia. Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:8 Topics: Anti-Arrhythmia Agents; Diagnosis, Differential; Drug Therapy, Combination; Electrocardiography; Flecainide; Heart; Humans; Lidocaine; Male; Middle Aged; Myocardial Ischemia; Tachycardia, Ventricular	1998
Decrease in the high frequency QRS components depending on the local conduction delay. Japanese circulation journal, 1998, Volume: 62, Issue:11 Topics: Animals; Disopyramide; Dogs; Electrocardiography; Flecainide; Fourier Analysis; Heart Conduction System; Lidocaine; Sodium Channel Blockers; Time	1998
ST segment elevation in the right precordial leads induced with class IC antiarrhythmic drugs: insight into the mechanism of Brugada syndrome. Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:2 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Flecainide; Follow-Up Studies; Heart Rate; Humans; Lidocaine; Male; Middle Aged; Procainamide; Recurrence; Tachycardia, Paroxysmal; Tachycardia, Ventricular; Wolff-Parkinson-White Syndrome	1999
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current. Circulation, 1999, Mar-30, Volume: 99, Issue:12 Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyramide; Dogs; Electrocardiography; Flecainide; Injections; Lidocaine; Piperidines; Pyridines; Sodium Channels; Ventricular Fibrillation; Verapamil	1999
Comparison of cocaine and Na+ channel blockers on cardio-respiratory function in the rabbit. European journal of pharmacology, 1999, Jul-14, Volume: 377, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cocaine; Dopamine Uptake Inhibitors; Electrocardiography; Female; Flecainide; Heart; Heart Rate; Lidocaine; Male; Procainamide; Quinidine; Rabbits; Respiration; Sodium Channel Blockers	1999
Effects of flecainide in patients with new SCN5A mutation: mutation-specific therapy for long-QT syndrome? Circulation, 2000, Apr-11, Volume: 101, Issue:14 Topics: Anti-Arrhythmia Agents; Case-Control Studies; Electrocardiography; Female; Flecainide; Heart; Heterozygote; Humans; Injections, Intravenous; Lidocaine; Long QT Syndrome; Male; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Pedigree; Sodium Channels	2000
Direct effects of class I antiarrhythmic drugs on epicardial electrograms in dogs. Japanese heart journal, 1999, Volume: 40, Issue:5 Topics: Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Electrocardiography; Flecainide; Lidocaine; Pericardium	1999
Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome. Circulation, 2000, Aug-22, Volume: 102, Issue:8 Topics: Anti-Arrhythmia Agents; Cell Line; Dose-Response Relationship, Drug; Flecainide; Genetic Linkage; Humans; Kinetics; Lidocaine; Long QT Syndrome; Membrane Potentials; NAV1.5 Voltage-Gated Sodium Channel; Point Mutation; Sodium Channel Blockers; Sodium Channels; Substrate Specificity	2000
Anisotropic effects of sodium channel blockers on the wavelength for ventricular excitation in dogs. Japanese circulation journal, 2000, Volume: 64, Issue:9 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Dogs; Electrocardiography; Electrophysiology; Flecainide; Heart Conduction System; Heart Ventricles; Lidocaine; Sodium Channel Blockers; Sodium Channels; Tachycardia, Ventricular; Ventricular Fibrillation; Ventricular Function	2000
Block of wild-type and inactivation-deficient cardiac sodium channels IFM/QQQ stably expressed in mammalian cells. Biophysical journal, 2000, Volume: 79, Issue:6 Topics: Amino Acid Substitution; Anti-Arrhythmia Agents; Cell Line; Cloning, Molecular; Disopyramide; Flecainide; Heart; Humans; Lidocaine; Membrane Potentials; Models, Biological; Myocardium; Recombinant Proteins; Sodium Channel Blockers; Sodium Channels; Transfection	2000
ST segment elevation in the right precordial leads following administration of class Ic antiarrhythmic drugs. Heart (British Cardiac Society), 2001, Volume: 85, Issue:1 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Electrocardiography; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged; Retrospective Studies	2001
Syncope in patients with atrial flutter during treatment with class Ic antiarrhythmic drugs. Journal of electrocardiology, 2001, Volume: 34, Issue:1 Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Catheter Ablation; Electrocardiography; Electrophysiologic Techniques, Cardiac; Exercise; Flecainide; Humans; Lidocaine; Male; Middle Aged; Syncope; Tachycardia	2001
Limited antifibrillatory effectiveness of clinically relevant concentrations of class I antiarrhythmics in isolated perfused rat hearts. Journal of cardiovascular pharmacology, 2002, Volume: 39, Issue:3 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circulation; Electrocardiography; Flecainide; Heart; Heart Rate; In Vitro Techniques; Lidocaine; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium Chloride; Quinidine; Rats; Rats, Wistar; Ventricular Fibrillation	2002
Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine. British journal of pharmacology, 2002, Volume: 136, Issue:5 Topics: Cation Transport Proteins; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flecainide; Humans; Lidocaine; Neural Inhibition; Potassium Channels; Potassium Channels, Voltage-Gated; Propafenone; Quinidine; Trans-Activators; Transcriptional Regulator ERG	2002
Atrial fibrillation threshold predicted long-term efficacy of pharmacological treatment of patients without structural heart disease. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2002, Volume: 4, Issue:4 Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Disopyramide; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Treatment Outcome	2002
Evaluation of the effect of bepridil on paroxysmal atrial fibrillation: relationship between efficacy and the f-f interval in surface ECG recordings. Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:1 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Bepridil; Calcium Channel Blockers; Electrocardiography; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged; Sodium Channel Blockers; Treatment Outcome	2003
Blockers of sodium and calcium entry protect axons from nitric oxide-mediated degeneration. Annals of neurology, 2003, Volume: 53, Issue:2 Topics: Anesthetics, Local; Animals; Axons; Bepridil; Calcium; Calcium Channel Blockers; Electrophysiology; Flecainide; Lidocaine; Male; Nerve Degeneration; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Rats; Rats, Sprague-Dawley; Sodium; Sodium Channel Blockers; Sodium-Calcium Exchanger; Spinal Nerve Roots	2003
Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues. The Journal of general physiology, 2003, Volume: 121, Issue:3 Topics: Anti-Arrhythmia Agents; Binding, Competitive; Cell Line; Flecainide; Humans; Intracellular Membranes; Lidocaine; Myocardium; Patch-Clamp Techniques; Sodium Channel Blockers; Sodium Channels	2003
Therapeutic monitoring of class I antiarrhythmic agents using high-resolution electrocardiography instead of blood samples. Circulation journal : official journal of the Japanese Circulation Society, 2003, Volume: 67, Issue:3 Topics: Aged; Anti-Arrhythmia Agents; Drug Monitoring; Electrocardiography; Female; Flecainide; Humans; Lidocaine; Male; Middle Aged; Piperidines	2003
The effects of class Ic antiarrhythmics on tetrodotoxin-resistant Na+ currents in rat sensory neurons. Anesthesia and analgesia, 2004, Volume: 99, Issue:2 Topics: Algorithms; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Drug Interactions; Drug Resistance; Flecainide; Ganglia, Spinal; Lidocaine; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels; Tetrodotoxin	2004
Differentiation of the electrophysiological effects on the atrial myocardium between the pure Na channel blocker, pilsicainide, and flecainide. Cardiovascular drugs and therapy, 2004, Volume: 18, Issue:4 Topics: Adult; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Heart Atria; Heart Conduction System; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Myocardium; Prospective Studies; Refractory Period, Electrophysiological; Research Design; Sodium Channel Blockers; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Ventricular; Treatment Outcome; Wolff-Parkinson-White Syndrome	2004
The cutaneous analgesic effect of class I antiarrhythmic drugs. Anesthesia and analgesia, 2007, Volume: 104, Issue:4 Topics: Analgesics; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Bupivacaine; Dose-Response Relationship, Drug; Flecainide; Injections, Subcutaneous; Lidocaine; Male; Mexiletine; Pain Measurement; Pain Threshold; Quinidine; Rats; Rats, Sprague-Dawley; Reflex; Skin; Sodium Channel Blockers; Time Factors	2007
Clinical and electrophysiological characteristics of patients having atrial flutter with 1:1 atrioventricular conduction. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2008, Volume: 10, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Case-Control Studies; Catheter Ablation; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Heart Atria; Heart Conduction System; Heart Ventricles; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Retrospective Studies; Risk Factors	2008
Predicting drug-induced slowing of conduction and pro-arrhythmia: identifying the 'bad' sodium current blockers. British journal of pharmacology, 2010, Volume: 160, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; CHO Cells; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Electric Conductivity; Ether-A-Go-Go Potassium Channels; Flecainide; Heart Conduction System; In Vitro Techniques; Lidocaine; Myocardial Reperfusion Injury; Patch-Clamp Techniques; Purkinje Fibers; Rabbits; Sodium Channel Blockers; Sodium Channels; Tachycardia, Ventricular; Ventricular Fibrillation	2010
Molecular determinants of state-dependent block of voltage-gated sodium channels by pilsicainide. British journal of pharmacology, 2010, Volume: 160, Issue:6 Topics: Brain; Cell Line; Flecainide; Heart; Humans; Lidocaine; Mexiletine; Muscle Proteins; Muscle, Skeletal; NAV1.1 Voltage-Gated Sodium Channel; NAV1.4 Voltage-Gated Sodium Channel; NAV1.5 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Patch-Clamp Techniques; Sodium Channel Blockers; Sodium Channels	2010
Inhibition of cardiac Ca2+ release channels (RyR2) determines efficacy of class I antiarrhythmic drugs in catecholaminergic polymorphic ventricular tachycardia. Circulation. Arrhythmia and electrophysiology, 2011, Volume: 4, Issue:2 Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Calsequestrin; Defibrillators, Implantable; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Countershock; Electrocardiography; Flecainide; Humans; Ion Channel Gating; Lidocaine; Male; Mice; Mice, Knockout; Mutation, Missense; Myocytes, Cardiac; Procainamide; Propafenone; Ryanodine Receptor Calcium Release Channel; Sodium Channel Blockers; Tachycardia, Ventricular; Time Factors; Young Adult	2011
A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms. Science translational medicine, 2011, Aug-31, Volume: 3, Issue:98 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Computer Simulation; Flecainide; Heart Conduction System; Heart Failure; Heart Ventricles; Humans; Kinetics; Lidocaine; Models, Cardiovascular; Rabbits; Reproducibility of Results; Sodium Channels	2011
Convulsions after normal dose of lidocaine: a probable drug interaction. British journal of anaesthesia, 2012, Volume: 108, Issue:4 Topics: Adrenergic alpha-Agonists; Aged; Anesthetics, Local; Anti-Arrhythmia Agents; Atrial Fibrillation; Brachial Plexus; Drug Interactions; Epinephrine; Female; Flecainide; Fractures, Bone; Humans; Lidocaine; Radial Nerve; Radius; Seizures	2012
Effects of Na+ channel blockers on extrasystolic stimulation-evoked changes in ventricular conduction and repolarization. Journal of cardiovascular pharmacology, 2014, Volume: 63, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiological Phenomena; Female; Flecainide; Guinea Pigs; Heart Ventricles; Lidocaine; Mexiletine; Quinidine; Sodium Channel Blockers; Tachycardia, Ventricular	2014
Significance of electrocardiogram recording in high intercostal spaces in patients with early repolarization syndrome. European heart journal, 2016, Feb-14, Volume: 37, Issue:7 Topics: Adult; Anti-Arrhythmia Agents; Brugada Syndrome; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Humans; Lidocaine; Male; Prognosis; Recurrence; Risk Assessment; Ventricular Fibrillation	2016
Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes. PloS one, 2016, Volume: 11, Issue:11 Topics: Ajmaline; Flecainide; Hot Temperature; Humans; Lidocaine; Myocytes, Cardiac; Patch-Clamp Techniques; Pluripotent Stem Cells; Polymerase Chain Reaction; Ranolazine; Sodium Channel Blockers; Sodium Channels	2016
Dynamic all-optical drug screening on cardiac voltage-gated ion channels. Scientific reports, 2018, 01-18, Volume: 8, Issue:1 Topics: Astemizole; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Flecainide; Gene Expression; HEK293 Cells; High-Throughput Screening Assays; Humans; Lidocaine; Membrane Potentials; NAV1.5 Voltage-Gated Sodium Channel; Optogenetics; Patch-Clamp Techniques; Phosphines; Plasmids; Potassium Channel Blockers; Quinidine; Voltage-Gated Sodium Channel Blockers	2018
Structural basis for antiarrhythmic drug interactions with the human cardiac sodium channel. Proceedings of the National Academy of Sciences of the United States of America, 2019, 02-19, Volume: 116, Issue:8 Topics: Amino Acid Sequence; Anti-Arrhythmia Agents; Binding Sites; Drug Interactions; Flecainide; Humans; Lidocaine; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; NAV1.5 Voltage-Gated Sodium Channel; Protein Binding; Protein Conformation; Sodium; Sodium Channels	2019
High-throughput quantification of ten antiarrhythmic drugs in human plasma using UPLC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Oct-15, Volume: 1129 Topics: Anti-Arrhythmia Agents; Atenolol; Bisoprolol; Carvedilol; Chromatography, High Pressure Liquid; Diltiazem; Flecainide; High-Throughput Screening Assays; Humans; Lidocaine; Metoprolol; Propranolol; Reproducibility of Results; Sotalol; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Verapamil	2019
Mixture effects of tetrodotoxin (TTX) and drugs targeting voltage-gated sodium channels on spontaneous neuronal activity in vitro. Toxicology letters, 2023, Jan-15, Volume: 373 Topics: Animals; Carbamazepine; Flecainide; Humans; Lidocaine; Rats; Riluzole; Tetrodotoxin; Voltage-Gated Sodium Channels	2023