flecainide and encainide

flecainide has been researched along with encainide in 132 studies

Research

Studies (132)

Timeframe	Studies, this research(%)	All Research%
pre-1990	57 (43.18)	18.7374
1990's	67 (50.76)	18.2507
2000's	5 (3.79)	29.6817
2010's	3 (2.27)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baizman, ER; Becker, C; Bell, RH; Birsner, NC; Bohnet, EA; Busacca, CA; Carabateas, PM; Chadwick, CC; Gruett, MD; Johnson, RE	1
Topliss, JG; Yoshida, F	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Dalvie, D; Loi, CM; Smith, DA	1
Jung, W; Lüderitz, B; Manz, M	1
Colatsky, TJ; Cullinan, CA; Follmer, CH	1
Huang, W	1
Tao, P; Tao, SQ	1
Tonkin, AM	1
Vaughan Williams, EM	2
Rabkin, SW	1
Greene, HL; Henthorn, RW; Katz, RJ; Roden, DM; Salerno, DM; Woosley, RL	1
Akiyama, T; Barker, AH; Campbell, WB; Friedman, L; Josephson, RA; Keller, M; Papa, L; Pawitan, Y; Rubbert, P	1
Pratt, CM	1
Akhtar, M; Breithardt, G; Camm, AJ; Coumel, P; Janse, MJ; Lazzara, R; Myerburg, RJ; Schwartz, PJ; Waldo, AL; Wellens, HJ	1
Katz, A; Knilans, TK; Prystowsky, EN	1
Lee, JH; Rosen, MR	1
Denes, P; Gillis, AM; Kammerling, JM; Pawitan, Y; Salerno, DM; Wilhelmsen, L	1
Gloor, HO	1
Akiyama, T; Greenberg, H; Kuo, CS; Pawitan, Y; Reynolds-Haertle, RA	1
Somberg, J	2
Kerin, NZ	1
Arensberg, D; Baker, A; Barker, AH; Echt, DS; Friedman, L; Greene, HL; Liebson, PR; Mitchell, LB; Obias-Manno, D; Peters, RW	1
Somberg, JC	2
Pritchett, EL; Wilkinson, WE	1
Bigger, JT; Epstein, AE; Hallstrom, AP; Reynolds-Haertle, RA; Romhilt, DW; Wyse, DG	1
Cohen, JD; Hallstrom, A; Mahmarian, J; McBride, R; Steinberg, JS; Wyse, DG	1
Benson, DW; Fish, FA; Gillette, PC	1
Garson, A; Perry, JC	1
Galløe, AM; Graudal, N	1
Antonaccio, MJ; Buchanan, JO; Fleming, JS; Iben, LG; Yocca, FD	1
Capone, RJ; el-Sherif, N; Geraci, TS; Handshaw, K; Morganroth, J; Pawitan, Y; Schlant, RC; Waldo, AL	1
Bigger, JT	3
Moye, LA; Pratt, CM	1
Anderson, JL	3
Marcus, FI	1
Chen, PS; Feld, GK; Fleck, RP; Meyer, D; Nicod, P	1
Kennedy, HL	1
Eldar, M; Franz, MR; Griffin, JC; Herre, JM; Oeff, M; Scheinman, MM; Titus, C	1
Cook, JR; Reiffel, JA	1
Case, CL; Gillette, PC	1
Moye, L; Pratt, CM	1
Turakhia, DP	1
Coumel, P	1
Bayés de Luna, A; Borja, J; Guindo, J; Madoery, C; Roman, M	1
Fifield, J; Pentel, PR; Salerno, DM	1
Barker, AH; Capone, RJ; Echt, DS; Greene, HL; Hallstrom, AP; McBride, R; Richardson, DW; Roden, DM	1
Anderson, JL; Barker, AH; Fowles, RE; Griffith, LS; Hallstrom, AP; Ledingham, RB; Reiffel, JA; Young, JB; Yusuf, S	1
Castellanos, A; Cox, MM; Fernandez, P; Huikuri, H; Interian, A; Kessler, KM; Myerburg, RJ; Terracall, E	1
Estes, NA; Manolis, AS; Salem, DN	1
Kates, RE; Liem, LB	1
Nightingale, SL	1
Lown, B; Podrid, PJ; Saini, V; Slater, W	1
Abi Samra, F	1
Coyle, JD; Schaal, SF	1
Ruskin, JN	1
Case, CL; Gillette, PC; Trippel, DL	1
Maloney, JD	1
Gottlieb, SS	1
Marcus, FI; Podrid, PJ	1
Camm, AJ; Garratt, C; Ward, DE	1
Bleske, BE; Chow, MS; Fisher, J; Kluger, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Roy, D	1
Engel, T; Kelliher, GJ; Kowey, P; Wetstein, L	1
Roden, DM	1
Echt, DS; Roden, DM; Woosley, RL	1
Bleifeld, W; Kuck, KH; Kunze, KP; Schlüter, M	1
Morganroth, J; Nestico, PF	2
Kates, RE	1
Horowitz, LN; Morganroth, J	1
Morganroth, J	1
Bettini, R; Disertori, M; Furlanello, F; Gramegna, L; Mosna, G; Vergara, G	1
Hammill, SC; Kreeger, RW	1
Gomoll, AW	1
Chase, SL; Sloskey, GE	1
Berns, E; Dougherty, AH; Naccarelli, GV; Rinkenberger, RL	1
Duckeck, W; Kuck, KH; Kunze, KP; Schlüter, M	1
Garson, A; Gothing, C; Moak, JP; Smith, RT; Strasburger, JF	1
Podrid, PJ	2
Atarashi, H; Hayakawa, H	1
Sanna, GP	1
Duff, HJ; Oates, JA; Roden, DM; Woosley, RL	1
Block, PJ; Winkle, RA	1
Pottage, A	1
Harrison, DC; Mead, RH	1
McDevitt, DG	1
Hugenholtz, PG; Serruys, PW; Vanhaleweyk, G	1
Camm, AJ	1
Orning, OM	1
Hellestrand, KJ	1
Luck, JC; Mann, DE; Pratt, CM; Wyndham, CR	1
Atallah, G; Kirkorian, G; Moleur, P; Touboul, P	1
Grey, E; Silverman, DI	1
Bigger, JT; Fleiss, JL; Rolnitzky, LM; Steinman, RC	1
Anderson, JL; Carlson, M; Davies, R; Duff, HJ; Greene, HL; Hallstrom, AP; Huther, M; Kammerling, JM; Romhilt, DW	1
Jung, W; Lüderitz, B; Manz, M; Mletzko, R; Nitsch, J	1
DeMaria, A; Gottlieb, S; Greene, HL; Hallstrom, A; Huther, M; Pratt, CM; Young, JB	1
Bigger, JT; Brooks, MM; Epstein, AE; Goldstein, S; Kennedy, HL; Ledingham, R; Pawitan, Y	1
Anderson, JL; Buckingham, TA; Carlson, MD; Carson, PE; Hallstrom, A; Henthorn, RW; Platia, EV	1
Anderson, JL; Capone, RJ; Cohen, JD; Epstein, AE; Hallstrom, AP; Liebson, PR; Rogers, WJ; Seals, AA; Wyse, DG	1
Barker, AH; Brooks, MM; Capone, R; Echt, DS; Greene, HL; Liebson, PR; Mitchell, LB; Peters, RW	1
Chow, MS; Fisher, JR; Kluger, J; Tisdale, JE	1
Brooks, MM; Gorkin, L; Kellen, J; Morris, M; Pawitan, Y; Schoenberger, JA; Schron, EB; Shumaker, S; Verter, J; Wiklund, I	1
Dwyer, EM; Echt, DS; Greenberg, HM; Hochman, JS; Peters, RW; Steinberg, JS	1
Brezsnyak, ML; Campion, J; Corum, J; Ettinger, A; Kellen, JC; McBride, R; Schron, E; Thomas, S; Todd, L	1
Brooks, MM; Friedmann, E; Goldner, F; Haakenson, C; Morris, M; Obias-Manno, D; Somelofski, C; Thomas, SA; Wimbush, F	1
Gill, RM; Reid, PR; Steinberg, MI; Sweeney, RJ	1
Anderson, JL; Karagounis, LA; Pratt, CM; Waldo, AL	1
Josephson, ME; Krishnan, SC	1
Dougherty, AH; Naccarelli, GV; Wiggins, S; Wolbrette, D	1

Reviews

33 review(s) available for flecainide and encainide

Article	Year
Treatment of ventricular arrhythmias after CAST. The Medical journal of Australia, 1992, Apr-06, Volume: 156, Issue:7 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Death, Sudden, Cardiac; Electrocardiography, Ambulatory; Encainide; Flecainide; Heart Ventricles; Humans; Moricizine; Myocardial Infarction; Ventricular Function, Left	1992
Classifying antiarrhythmic actions: by facts or speculation. Journal of clinical pharmacology, 1992, Volume: 32, Issue:11 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Encainide; Flecainide; Heart; Humans; Imidazoles	1992
CAST and beyond. Implications of the Cardiac Arrhythmia Suppression Trial. Task Force of the Working Group on Arrhythmias of the European Society of Cardiology. Circulation, 1990, Volume: 81, Issue:3 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Double-Blind Method; Encainide; Flecainide; Humans; Moricizine; Multicenter Studies as Topic; Phenothiazines; Randomized Controlled Trials as Topic	1990
Ventricular arrhythmias: risk stratification and approach to therapy after the Cardiac Arrhythmia Suppression Trial (CAST). Pacing and clinical electrophysiology : PACE, 1990, Volume: 13, Issue:11 Pt 2 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Heart Ventricles; Humans; Pilot Projects; Risk Factors	1990
[What is the latest in anti-arrhythmia therapy?]. Schweizerische medizinische Wochenschrift, 1991, Nov-23, Volume: 121, Issue:47 Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Death, Sudden, Cardiac; Encainide; Flecainide; Humans	1991
Significance of classifying antiarrhythmic actions since the cardiac arrhythmia suppression trial. Journal of clinical pharmacology, 1991, Volume: 31, Issue:2 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Electrocardiography; Encainide; Flecainide; Humans; Propafenone	1991
The Cardiac Arrhythmia Suppression Trial: background, interim results and implications. The American journal of cardiology, 1990, Jan-16, Volume: 65, Issue:4 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Research Design; Survival Analysis	1990
Clinical implications of new studies in the treatment of benign, potentially malignant and malignant ventricular arrhythmias. The American journal of cardiology, 1990, Jan-16, Volume: 65, Issue:4 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Heart Ventricles; Humans; Risk Factors; Sotalol; Ventricular Fibrillation	1990
Comparisons of efficacy and tolerance of moricizine with other antiarrhythmic agents in the treatment of chronic ventricular arrhythmias. The American journal of cardiology, 1990, Feb-20, Volume: 65, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Double-Blind Method; Encainide; Female; Flecainide; Humans; Male; Moricizine; Phenothiazines; Propranolol; Quinidine; Randomized Controlled Trials as Topic	1990
Reassessment of benefit-risk ratio and treatment algorithms for antiarrhythmic drug therapy after the cardiac arrhythmia suppression trial. Journal of clinical pharmacology, 1990, Volume: 30, Issue:11 Topics: Algorithms; Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Drug Evaluation; Encainide; Flecainide; Humans; Odds Ratio; Time Factors; Ventricular Fibrillation	1990
Update: cardiac antiarrhythmic drugs. Comprehensive therapy, 1989, Volume: 15, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Propafenone; Propanolamines	1989
The clinical use of class IC antiarrhythmic drugs. The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1989, Volume: 141, Issue:5 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Humans; Propafenone	1989
New antiarrhythmic agents in pediatrics. Pediatric clinics of North America, 1989, Volume: 36, Issue:5 Topics: Action Potentials; Amiodarone; Anilides; Anti-Arrhythmia Agents; Atenolol; Child; Child, Preschool; Encainide; Flecainide; Heart Conduction System; Humans; Infant; Pediatrics	1989
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Antiarrhythmic drugs. Canadian Anaesthetists' Society journal, 1986, Volume: 33, Issue:3 Pt 2 Topics: Action Potentials; Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium Channel Blockers; Cell Membrane; Disopyramide; Electrophysiology; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide	1986
Clinical pharmacology of antiarrhythmic agents. Cardiovascular clinics, 1985, Volume: 16, Issue:1 Topics: Adrenergic beta-Antagonists; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Calcium Channel Blockers; Electrophysiology; Encainide; Flecainide; Heart Conduction System; Humans; Lidocaine; Moricizine; Phenothiazines; Piperidines; Quaternary Ammonium Compounds; Sotalol; Tocainide	1985
Pharmacologic information required for design of programmed electrical stimulation protocols. Circulation, 1986, Volume: 73, Issue:2 Pt 2 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Dogs; Drug Evaluation; Electric Stimulation; Encainide; Flecainide; Heart Conduction System; Humans; Piperidines	1986
Effects of congestive heart failure on the pharmacokinetics and pharmacodynamics of antiarrhythmic agents. The American journal of cardiology, 1986, Jan-31, Volume: 57, Issue:3 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Digitalis; Disopyramide; Drug Interactions; Encainide; Flecainide; Half-Life; Heart Failure; Hemodynamics; Humans; Kidney; Kinetics; Lidocaine; Liver; Piperidines; Plants, Medicinal; Plants, Toxic; Potassium; Procainamide; Quinidine; Regional Blood Flow; Tocainide	1986
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment. Cardiology clinics, 1986, Volume: 4, Issue:2 Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil	1986
Antiarrhythmic agents for chronic ventricular arrhythmias. Comprehensive therapy, 1987, Volume: 13, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Procainamide; Propranolol; Quinidine; Tocainide	1987
Flecainide and encainide. European heart journal, 1987, Volume: 8 Suppl A Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Humans	1987
New antiarrhythmic drugs: tocainide, mexiletine, flecainide, encainide, and amiodarone. Mayo Clinic proceedings, 1987, Volume: 62, Issue:11 Topics: Administration, Oral; Amiodarone; Anilides; Anti-Arrhythmia Agents; Drug Interactions; Encainide; Flecainide; Heart Conduction System; Humans; Lidocaine; Mexiletine; Tachycardia; Tocainide	1987
Encainide hydrochloride and flecainide acetate: two class 1c antiarrhythmic agents. Clinical pharmacy, 1987, Volume: 6, Issue:11 Topics: Anilides; Arrhythmias, Cardiac; Drug Interactions; Encainide; Flecainide; Humans	1987
Antiarrhythmic drug therapy (Part 2). Benefits and hazards. Chest, 1985, Volume: 88, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1985
Hemodynamic effects of antiarrhythmic drugs. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide	1983
Clinical profiles of newer class I antiarrhythmic agents--tocainide, mexiletine, encainide, flecainide and lorcainide. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Administration, Oral; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Injections, Intravenous; Kinetics; Lidocaine; Mexiletine; Piperidines; Tocainide	1983
Therapy with investigational antiarrhythmic drugs. The Medical clinics of North America, 1984, Volume: 68, Issue:5 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Tocainide	1984
Haemodynamic effects of encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Piperidines; Tocainide	1984
Cardiac electrophysiology of four new antiarrhythmic drugs--encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Action Potentials; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrocardiography; Electrophysiology; Encainide; Flecainide; Heart; Heart Conduction System; Humans; Lidocaine; Piperidines; Sinoatrial Node; Tocainide	1984
Comparison of the efficacy of newly developed antiarrhythmic drugs in the treatment of ventricular tachyarrhythmias. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Coronary Disease; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Piperidines; Tachycardia; Tocainide; Ventricular Fibrillation	1984
Investigational antiarrhythmic drugs for the treatment of ventricular rhythm disturbances. Cardiology clinics, 1984, Volume: 2, Issue:1 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Tocainide	1984
[New antiarrythmic drugs: mexiletine, tocainide, lorcainide, encainide, flecainide, propafenone, cipralan, sotalol]. Annales de cardiologie et d'angeiologie, 1982, Volume: 31, Issue:7 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Sotalol; Tocainide	1982

Trials

44 trial(s) available for flecainide and encainide

Article	Year
The Cardiac Arrhythmia Suppression Trial: first CAST ... then CAST-II. Journal of the American College of Cardiology, 1992, Volume: 19, Issue:5 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; Encainide; Flecainide; Humans; Moricizine; Myocardial Infarction; Survival Rate	1992
Effects of advancing age on the efficacy and side effects of antiarrhythmic drugs in post-myocardial infarction patients with ventricular arrhythmias. The CAST Investigators. Journal of the American Geriatrics Society, 1992, Volume: 40, Issue:7 Topics: Adult; Age Factors; Aged; Aging; Arrhythmias, Cardiac; Drug Therapy, Combination; Encainide; Flecainide; Follow-Up Studies; Humans; Logistic Models; Middle Aged; Moricizine; Myocardial Infarction; Prognosis; Stroke Volume	1992
Proarrhythmic potential of moricizine: strengths and limitations of a data base analysis. The American journal of cardiology, 1990, Feb-20, Volume: 65, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Encainide; Flecainide; Humans; Information Systems; Moricizine; Phenothiazines; Tachycardia	1990
CAST and beyond. Implications of the Cardiac Arrhythmia Suppression Trial. Task Force of the Working Group on Arrhythmias of the European Society of Cardiology. Circulation, 1990, Volume: 81, Issue:3 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Double-Blind Method; Encainide; Flecainide; Humans; Moricizine; Multicenter Studies as Topic; Phenothiazines; Randomized Controlled Trials as Topic	1990
Prevalence, characteristics and significance of ventricular premature complexes and ventricular tachycardia detected by 24-hour continuous electrocardiographic recording in the Cardiac Arrhythmia Suppression Trial. CAST Investigators. The American journal of cardiology, 1991, Oct-01, Volume: 68, Issue:9 Topics: Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cross-Sectional Studies; Electric Countershock; Electrocardiography, Ambulatory; Encainide; Flecainide; Heart Arrest; Humans; Pre-Excitation Syndromes; Tachycardia	1991
Increased risk of death and cardiac arrest from encainide and flecainide in patients after non-Q-wave acute myocardial infarction in the Cardiac Arrhythmia Suppression Trial. CAST Investigators. The American journal of cardiology, 1991, Dec-15, Volume: 68, Issue:17 Topics: Cardiac Complexes, Premature; Cause of Death; Drug Combinations; Electrocardiography; Encainide; Female; Flecainide; Follow-Up Studies; Heart Arrest; Humans; Male; Middle Aged; Moricizine; Myocardial Infarction; Placebos; Risk Factors; United States	1991
Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial. The New England journal of medicine, 1991, Mar-21, Volume: 324, Issue:12 Topics: Actuarial Analysis; Anilides; Arrhythmias, Cardiac; Electrocardiography; Encainide; Flecainide; Follow-Up Studies; Heart Arrest; Heart Failure; Humans; Morbidity; Myocardial Infarction; Patient Compliance	1991
Events in the Cardiac Arrhythmia Suppression Trial (CAST): mortality in the entire population enrolled. Journal of the American College of Cardiology, 1991, Volume: 18, Issue:1 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Moricizine; Myocardial Infarction	1991
Events in the Cardiac Arrhythmia Suppression Trial (CAST): mortality in patients surviving open label titration but not randomized to double-blind therapy. Journal of the American College of Cardiology, 1991, Volume: 18, Issue:1 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Moricizine; Myocardial Infarction; Regression Analysis	1991
Events in the cardiac arrhythmia suppression trial: baseline predictors of mortality in placebo-treated patients. Journal of the American College of Cardiology, 1991, Nov-15, Volume: 18, Issue:6 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chi-Square Distribution; Double-Blind Method; Encainide; Female; Flecainide; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Placebos; Proportional Hazards Models; Prospective Studies; Reference Values; Risk Factors	1991
The events surrounding the removal of encainide and flecainide from the Cardiac Arrhythmia Suppression Trial (CAST) and why CAST is continuing with moricizine. Journal of the American College of Cardiology, 1990, Volume: 15, Issue:1 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Humans; Mass Media; Moricizine; National Institutes of Health (U.S.); Phenothiazines; Randomized Controlled Trials as Topic; United States; United States Food and Drug Administration	1990
The Cardiac Arrhythmia Suppression Trial: background, interim results and implications. The American journal of cardiology, 1990, Jan-16, Volume: 65, Issue:4 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Humans; Myocardial Infarction; Randomized Controlled Trials as Topic; Research Design; Survival Analysis	1990
Implications of the Cardiac Arrhythmia Suppression Trial for antiarrhythmic drug treatment. The American journal of cardiology, 1990, Feb-20, Volume: 65, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; Encainide; Europe; Flecainide; Humans; Moricizine; Multicenter Studies as Topic; Phenothiazines; Randomized Controlled Trials as Topic; Research Design; United States; United States Food and Drug Administration	1990
Comparisons of efficacy and tolerance of moricizine with other antiarrhythmic agents in the treatment of chronic ventricular arrhythmias. The American journal of cardiology, 1990, Feb-20, Volume: 65, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Double-Blind Method; Encainide; Female; Flecainide; Humans; Male; Moricizine; Phenothiazines; Propranolol; Quinidine; Randomized Controlled Trials as Topic	1990
CAST and beyond. Implications of the cardiac arrhythmia suppression trials. By the Task Force of the Working Group on Arrhythmias of the European Society of Cardiology. European heart journal, 1990, Volume: 11, Issue:3 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; Encainide; Flecainide; Humans; Moricizine; Multicenter Studies as Topic; Phenothiazines; Randomized Controlled Trials as Topic	1990
Encainide versus flecainide in the treatment of chronic resistant paroxysmal atrial tachyarrhythmias. Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 3 Topics: Adult; Anilides; Anti-Arrhythmia Agents; Atrial Fibrillation; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Tachycardia, Paroxysmal	1990
Recasting the approach to the treatment of potentially malignant ventricular arrhythmias after the CAST study. Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:3 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cricetinae; Encainide; Flecainide; Humans; Ventricular Function, Left	1990
Clinical aspects of trial design: what can we expect from the cardiac arrhythmia suppression trial? Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:3 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Electric Stimulation; Electrocardiography; Encainide; Flecainide; Heart; Humans; Randomized Controlled Trials as Topic; Research Design; Ventricular Function	1990
Lack of effect of hypertonic sodium bicarbonate on QRS duration in patients taking therapeutic doses of class IC antiarrhythmic drugs. Journal of clinical pharmacology, 1990, Volume: 30, Issue:9 Topics: Aged; Aged, 80 and over; Anilides; Anti-Arrhythmia Agents; Bicarbonates; Double-Blind Method; Electrocardiography; Encainide; Female; Flecainide; Humans; Hypertonic Solutions; Male; Middle Aged; Pilot Projects; Risk Factors; Sodium; Sodium Bicarbonate; Time Factors	1990
Recruitment and baseline description of patients in the Cardiac Arrhythmia Pilot Study. The Cardiac Arrhythmia Pilot Study (CAPS) investigators. The American journal of cardiology, 1988, Apr-01, Volume: 61, Issue:10 Topics: Anilides; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrocardiography; Encainide; Feasibility Studies; Female; Flecainide; Humans; Imipramine; Male; Middle Aged; Moricizine; Myocardial Infarction; Phenothiazines; Pilot Projects; Random Allocation; Stroke Volume; United States	1988
Congestive heart failure after acute myocardial infarction in patients receiving antiarrhythmic agents for ventricular premature complexes (Cardiac Arrhythmia Pilot Study). The American journal of cardiology, 1989, Feb-15, Volume: 63, Issue:7 Topics: Anilides; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Double-Blind Method; Encainide; Female; Flecainide; Heart Failure; Humans; Imipramine; Male; Middle Aged; Moricizine; Myocardial Infarction; Phenothiazines; Random Allocation; Stroke Volume	1989
Relation of baseline characteristics to suppression of ventricular arrhythmias during placebo and active antiarrhythmic therapy in patients after myocardial infarction. Circulation, 1989, Volume: 79, Issue:3 Topics: Anilides; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Encainide; Flecainide; Humans; Imipramine; Moricizine; Multicenter Studies as Topic; Myocardial Infarction; Phenothiazines; Pilot Projects; Random Allocation; Statistics as Topic; Stroke Volume	1989
Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction. The New England journal of medicine, 1989, 08-10, Volume: 321, Issue:6 Topics: Aged; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; Death, Sudden; Encainide; Female; Flecainide; Follow-Up Studies; Humans; Male; Middle Aged; Moricizine; Myocardial Infarction; Phenothiazines; Random Allocation	1989
Encainide and flecainide: are they interchangeable? American heart journal, 1989, Volume: 117, Issue:6 Topics: Adolescent; Adult; Aged; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Encainide; Exercise Test; Female; Flecainide; Heart Rate; Humans; Male; Middle Aged; Monitoring, Physiologic	1989
An interim perspective on the removal of encainide and flecainide from the cardiac arrhythmia suppression trial. DICP : the annals of pharmacotherapy, 1989, Volume: 23, Issue:6 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Encainide; Ethics, Medical; Flecainide; Humans; Myocardial Infarction; United States; United States Food and Drug Administration	1989
Consequences of the Cardiac Arrhythmia Suppression Trial: calamity or clarity? Cleveland Clinic journal of medicine, 1989, Volume: 56, Issue:6 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Consumer Product Safety; Double-Blind Method; Encainide; Flecainide; Humans; Information Services; National Institutes of Health (U.S.); Random Allocation; United States; United States Food and Drug Administration	1989
The use of antiarrhythmic agents in heart failure: implications of CAST. American heart journal, 1989, Volume: 118, Issue:5 Pt 1 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Encainide; Flecainide; Heart Failure; Hemodynamics; Humans; Risk Factors	1989
Lessons to be learned from the cardiac arrhythmia suppression trial. The American journal of cardiology, 1989, Nov-15, Volume: 64, Issue:18 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Encainide; Flecainide; Humans; Prognosis; Risk Factors	1989
Lessons from the cardiac arrhythmia suppression trial. BMJ (Clinical research ed.), 1989, Sep-30, Volume: 299, Issue:6703 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Encainide; Flecainide; Humans; Moricizine; Myocardial Infarction; Phenothiazines; United States	1989
Flecainide and CAST. Lancet (London, England), 1989, Aug-26, Volume: 2, Issue:8661 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Evaluation; Encainide; Flecainide; Humans; Multicenter Studies as Topic; Myocardial Infarction; Product Surveillance, Postmarketing; Random Allocation	1989
Effects of encainide, flecainide, imipramine and moricizine on ventricular arrhythmias during the year after acute myocardial infarction: the CAPS. The American journal of cardiology, 1988, Mar-01, Volume: 61, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Encainide; Female; Flecainide; Heart Failure; Humans; Imipramine; Male; Middle Aged; Moricizine; Myocardial Infarction; Phenothiazines; Random Allocation; Stroke Volume	1988
Efficacy and safety of class IC antiarrhythmic agents for the treatment of coexisting supraventricular and ventricular tachycardia. The American journal of cardiology, 1988, Aug-25, Volume: 62, Issue:6 Topics: Anilides; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Clinical Trials as Topic; Electrocardiography; Encainide; Female; Flecainide; Follow-Up Studies; Humans; Male; Middle Aged; Monitoring, Physiologic; Tachycardia; Tachycardia, Supraventricular; Time Factors	1988
Selection of an antiarrhythmic drug for a sudden-death-prevention trial. American heart journal, 1982, Volume: 103, Issue:4 Pt 2 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Encainide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Moricizine; Morpholines; Phenothiazines; Piperidines; Tocainide; Verapamil	1982
Predicting mortality after myocardial infarction from the response of RR variability to antiarrhythmic drug therapy. Journal of the American College of Cardiology, 1994, Mar-01, Volume: 23, Issue:3 Topics: Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Electrocardiography, Ambulatory; Encainide; Female; Flecainide; Follow-Up Studies; Heart Conduction System; Humans; Male; Middle Aged; Moricizine; Myocardial Infarction; Risk Factors; Signal Processing, Computer-Assisted	1994
Time to arrhythmic, ischemic, and heart failure events: exploratory analyses to elucidate mechanisms of adverse drug effects in the Cardiac Arrhythmia Suppression Trial. American heart journal, 1995, Volume: 130, Issue:1 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Double-Blind Method; Encainide; Flecainide; Heart Failure; Humans; Moricizine; Myocardial Infarction; Myocardial Ischemia; Risk Factors; Survival Analysis; Time Factors	1995
Relations between heart failure, ejection fraction, arrhythmia suppression and mortality: analysis of the Cardiac Arrhythmia Suppression Trial. Journal of the American College of Cardiology, 1995, Volume: 25, Issue:6 Topics: Arrhythmias, Cardiac; Electrocardiography; Encainide; Female; Flecainide; Heart Failure; Humans; Male; Middle Aged; Moricizine; Multivariate Analysis; Myocardial Infarction; Predictive Value of Tests; Prognosis; Prospective Studies; Regression Analysis; Stroke Volume; Survival Analysis	1995
Association between ease of suppression of ventricular arrhythmia and survival. Circulation, 1995, Jan-01, Volume: 91, Issue:1 Topics: Aged; Cross-Over Studies; Encainide; Flecainide; Follow-Up Studies; Humans; Middle Aged; Moricizine; Risk Factors; Ventricular Fibrillation	1995
Interaction of baseline characteristics with the hazard of encainide, flecainide, and moricizine therapy in patients with myocardial infarction. A possible explanation for increased mortality in the Cardiac Arrhythmia Suppression Trial (CAST). Circulation, 1994, Volume: 90, Issue:6 Topics: Arrhythmias, Cardiac; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Moricizine; Myocardial Infarction; Statistics as Topic; Survival Analysis	1994
Mortality following ventricular arrhythmia suppression by encainide, flecainide, and moricizine after myocardial infarction. The original design concept of the Cardiac Arrhythmia Suppression Trial (CAST). JAMA, 1993, Nov-24, Volume: 270, Issue:20 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Moricizine; Myocardial Infarction; Survival Analysis; Ventricular Function, Left	1993
Circadian pattern of arrhythmic death in patients receiving encainide, flecainide or moricizine in the Cardiac Arrhythmia Suppression Trial (CAST). Journal of the American College of Cardiology, 1994, Volume: 23, Issue:2 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Aspirin; Circadian Rhythm; Death, Sudden, Cardiac; Double-Blind Method; Encainide; Flecainide; Heart Arrest; Humans; Moricizine; Sympathetic Nervous System	1994
Psychosocial predictors of mortality in the Cardiac Arrhythmia Suppression Trial-1 (CAST-1). The American journal of cardiology, 1993, Feb-01, Volume: 71, Issue:4 Topics: Arrhythmias, Cardiac; Chi-Square Distribution; Encainide; Flecainide; Humans; Moricizine; Myocardial Infarction; Prognosis; Psychological Tests; Psychology, Social; Regression Analysis; Social Support	1993
Interaction of ischaemia and encainide/flecainide treatment: a proposed mechanism for the increased mortality in CAST I. British heart journal, 1995, Volume: 74, Issue:6 Topics: Angina Pectoris; Anti-Arrhythmia Agents; Databases, Factual; Death, Sudden, Cardiac; Drug Interactions; Encainide; Flecainide; Heart Failure; Humans; Myocardial Infarction; Myocardial Ischemia; Retrospective Studies; Syncope; United States	1995
The Cardiac Arrhythmia Suppression Trial: Implications for nursing practice. American journal of critical care : an official publication, American Association of Critical-Care Nurses, 1996, Volume: 5, Issue:1 Topics: Aged; Anti-Arrhythmia Agents; Critical Care; Death, Sudden, Cardiac; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Monitoring, Physiologic; Moricizine; Myocardial Infarction; Nursing Assessment; Survival Rate; Ventricular Premature Complexes	1996
Adherence and arrhythmic mortality in the cardiac arrhythmia suppression trial (CAST). Annals of epidemiology, 1996, Volume: 6, Issue:2 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Female; Flecainide; Health Behavior; Humans; Male; Middle Aged; Patient Compliance	1996

Other Studies

58 other study(ies) available for flecainide and encainide

Article	Year
4,5-Dihydro-1-phenyl-1H-2,4-benzodiazepines: novel antiarrhythmic agents. Journal of medicinal chemistry, 1993, Oct-29, Volume: 36, Issue:22 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzodiazepines; Cats; Disease Models, Animal; Dogs; Guinea Pigs; Heart Ventricles; Male; Myocardial Contraction; Myocardial Infarction; Potassium Channels; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Sodium Channels; Structure-Activity Relationship	1993
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
[Combination anti-arrhythmic drug therapy]. Zeitschrift fur Kardiologie, 1992, Volume: 81 Suppl 4 Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Drug Therapy, Combination; Electrocardiography, Ambulatory; Encainide; Flecainide; Humans; Mexiletine; Sotalol; Tachycardia; Tocainide	1992
Differential block of cardiac delayed rectifier current by class Ic antiarrhythmic drugs: evidence for open channel block and unblock. Cardiovascular research, 1992, Volume: 26, Issue:11 Topics: Animals; Anti-Arrhythmia Agents; Cats; Electromyography; Encainide; Flecainide; Membrane Potentials; Muscles; Phenylurea Compounds; Potassium; Potassium Channels; Reaction Time; Sodium	1992
[A critical evaluation of the cardiac arrhythmia suppression trial study]. Zhonghua xin xue guan bing za zhi, 1992, Volume: 20, Issue:4 Topics: Anti-Arrhythmia Agents; Clinical Trials, Phase IV as Topic; Encainide; Flecainide; Humans	1992
[Cardiac arrhythmia suppression trial]. Zhonghua xin xue guan bing za zhi, 1992, Volume: 20, Issue:4 Topics: Anti-Arrhythmia Agents; Clinical Trials, Phase IV as Topic; Encainide; Flecainide; Humans	1992
Effect of antiarrhythmic drugs on choline uptake in cardiac cells in culture. Cardiovascular research, 1992, Volume: 26, Issue:1 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Chick Embryo; Choline; Dose-Response Relationship, Drug; Encainide; Flecainide; Heart; Lidocaine; Myocardium; Propafenone; Tocainide	1992
Use-dependent actions and effects on transmembrane action potentials of flecainide, encainide, and ethmozine in canine Purkinje fibers. Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:2 Topics: Action Potentials; Animals; Cell Membrane; Culture Techniques; Dogs; Encainide; Flecainide; Kinetics; Moricizine; Purkinje Fibers	1991
The spectrum of CAST I and II. Journal of clinical pharmacology, 1991, Volume: 31, Issue:11 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Death, Sudden, Cardiac; Encainide; Flecainide; Humans; Moricizine; Randomized Controlled Trials as Topic	1991
Crime, misdemeanor, and arrhythmia decoding CAST. Journal of clinical pharmacology, 1991, Volume: 31, Issue:11 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Encainide; Flecainide; Heart Ventricles; Humans; Moricizine; Myocardial Infarction; Randomized Controlled Trials as Topic; Research Design; Risk Factors	1991
Drug classification and actions. Journal of clinical pharmacology, 1991, Volume: 31, Issue:2 Topics: Anilides; Anti-Arrhythmia Agents; Encainide; Flecainide; Humans; Moricizine	1991
Mortality in patients treated with flecainide and encainide for supraventricular arrhythmias. The American journal of cardiology, 1991, May-01, Volume: 67, Issue:11 Topics: Adult; Aged; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Female; Flecainide; Follow-Up Studies; Humans; Male; Middle Aged; North Carolina; Survival Rate; Tachycardia, Supraventricular; United States	1991
Proarrhythmia, cardiac arrest and death in young patients receiving encainide and flecainide. The Pediatric Electrophysiology Group. Journal of the American College of Cardiology, 1991, Volume: 18, Issue:2 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Death, Sudden; Encainide; Flecainide; Heart Arrest; Humans; Incidence; Retrospective Studies; Risk Factors; Tachycardia; Tachycardia, Supraventricular	1991
Encainide and flecainide in children: separating the wheat from the chaff. Journal of the American College of Cardiology, 1991, Volume: 18, Issue:2 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Encainide; Flecainide; Humans; Risk Factors	1991
Cardiac arrhythmia suppression trial. The New England journal of medicine, 1991, Aug-22, Volume: 325, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Biological Availability; Encainide; Flecainide; Humans	1991
Effect of encainide, ODE, MODE, and flecainide on ADP/5-HT induced platelet aggregation and in the anesthetized dog coronary artery stenosis-occlusion model of intravascular thrombosis. Cardiovascular drugs and therapy, 1991, Volume: 5, Issue:4 Topics: Adenosine Diphosphate; Anilides; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Coronary Thrombosis; Disease Models, Animal; Dogs; Encainide; Flecainide; Heart Rate; Platelet Aggregation; Platelet Aggregation Inhibitors; Serotonin; Ventricular Function, Left	1991
The hazards of using type 1C antiarrhythmic drugs for the treatment of paroxysmal atrial fibrillation. The American journal of cardiology, 1990, Aug-01, Volume: 66, Issue:3 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Encainide; Flecainide; Hemodynamics; Humans; Propafenone	1990
Possible atrial proarrhythmic effects of class 1C antiarrhythmic drugs. The American journal of cardiology, 1990, Aug-01, Volume: 66, Issue:3 Topics: Aged; Anilides; Anti-Arrhythmia Agents; Atrial Flutter; Electrocardiography; Encainide; Female; Flecainide; Humans; Male; Tachycardia, Supraventricular	1990
Late proarrhythmia and understanding the time of occurrence of proarrhythmia. The American journal of cardiology, 1990, Nov-01, Volume: 66, Issue:15 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Humans	1990
Inefficacy and proarrhythmic effects of flecainide and encainide for sustained ventricular tachycardia and ventricular fibrillation. Annals of internal medicine, 1990, Nov-01, Volume: 113, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiology; Encainide; Flecainide; Follow-Up Studies; Humans; Middle Aged; Tachycardia; Time Factors; Ventricular Fibrillation	1990
Physician attitudes toward the use of type IC antiarrhythmics after the Cardiac Arrhythmia Suppression Trial (CAST). The American journal of cardiology, 1990, Nov-15, Volume: 66, Issue:17 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Attitude of Health Personnel; Drug Utilization; Encainide; Flecainide; Humans; Physicians; Practice Patterns, Physicians'; Randomized Controlled Trials as Topic; Surveys and Questionnaires; United States; United States Food and Drug Administration	1990
Treatment of ventricular arrhythmias in children without structural heart disease with class IC agents as guided by invasive electrophysiology. The American journal of cardiology, 1990, Nov-15, Volume: 66, Issue:17 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Child; Electrophysiology; Encainide; Female; Flecainide; Humans; Male; Tachycardia	1990
The cardiac arrhythmia suppression trial: implications for antiarrhythmic drug development. Journal of clinical pharmacology, 1990, Volume: 30, Issue:11 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Drug Evaluation; Encainide; Flecainide; Humans; Pilot Projects; Time Factors	1990
Antiarrhythmic therapy--conventional wisdom challenged. The Journal of the Association of Physicians of India, 1990, Volume: 38, Issue:8 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Humans	1990
Reversal of proarrhythmic effects of flecainide acetate and encainide hydrochloride by propranolol. Circulation, 1989, Volume: 80, Issue:6 Topics: Aged; Anilides; Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Encainide; Flecainide; Humans; Male; Middle Aged; Propranolol; Tachycardia	1989
Electrophysiologic effects, efficacy and tolerance of class Ic antiarrhythmic agents in Wolff-Parkinson-White syndrome. The American journal of cardiology, 1989, Mar-15, Volume: 63, Issue:11 Topics: Adult; Aged; Anilides; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Drug Tolerance; Electrocardiography; Electrophysiology; Encainide; Female; Flecainide; Follow-Up Studies; Heart Conduction System; Humans; Male; Middle Aged; Prospective Studies; Time Factors; Wolff-Parkinson-White Syndrome	1989
Drugs for cardiac arrhythmias: new warning. The Medical letter on drugs and therapeutics, 1989, May-19, Volume: 31, Issue:792 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Humans	1989
From the Food and Drug Administration. JAMA, 1989, Jun-16, Volume: 261, Issue:23 Topics: Allergens; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Child; Drug Prescriptions; Encainide; Flecainide; Humans; Mortality; Patient Compliance	1989
The cardiac arrhythmia suppression trial (CAST). The New England journal of medicine, 1989, Aug-10, Volume: 321, Issue:6 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Death, Sudden; Encainide; Flecainide; Humans; Myocardial Infarction; Pilot Projects	1989
Acute effects of combination of IB and IC antiarrhythmics for the treatment of ventricular tachycardia. Journal of clinical pharmacology, 1989, Volume: 29, Issue:11 Topics: Anilides; Anti-Arrhythmia Agents; Blood Pressure; Drug Therapy, Combination; Electric Stimulation; Electrocardiography; Encainide; Flecainide; Heart Rate; Hemodynamics; Humans; Lidocaine; Male; Middle Aged; Refractory Period, Electrophysiological; Tachycardia	1989
The cardiac arrhythmia suppression trial. The New England journal of medicine, 1989, Dec-21, Volume: 321, Issue:25 Topics: Aged; Anilides; Arrhythmias, Cardiac; Encainide; Flecainide; Humans; Male	1989
Effect of encainide and flecainide on chronic ectopic atrial tachycardia. Journal of the American College of Cardiology, 1986, Volume: 7, Issue:5 Topics: Adult; Anilides; Chronic Disease; Electrophysiology; Encainide; Female; Flecainide; Heart Atria; Humans; Male; Middle Aged; Piperidines; Tachycardia	1986
Metabolites of antiarrhythmic drugs: are they clinically important? Rational drug therapy, 1986, Volume: 20, Issue:5 Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Procainamide; Quinidine	1986
Second generation antiarrhythmic agents: have we reached antiarrhythmic Nirvana? Journal of the American College of Cardiology, 1987, Volume: 9, Issue:2 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Tocainide	1987
Risk factors for the development of proarrhythmic events. The American journal of cardiology, 1987, Apr-30, Volume: 59, Issue:11 Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Encainide; Flecainide; Hospitalization; Humans; Information Systems; Risk; Tachycardia	1987
Assessment of drug effects on spontaneous and induced ventricular arrhythmias in a 24-h canine infarction model. Arzneimittel-Forschung, 1987, Volume: 37, Issue:7 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disopyramide; Dogs; Electrocardiography; Encainide; Female; Flecainide; Male; Myocardial Infarction; Sotalol	1987
Encainide versus flecainide for chronic atrial and junctional ectopic tachycardia. The American journal of cardiology, 1988, Dec-20, Volume: 62, Issue:19 Topics: Administration, Oral; Adolescent; Adult; Aged; Anilides; Anti-Arrhythmia Agents; Chronic Disease; Electrocardiography; Electrophysiology; Encainide; Exercise Test; Female; Flecainide; Heart Conduction System; Humans; Infusions, Intravenous; Male; Middle Aged; Tachycardia, Ectopic Atrial; Tachycardia, Ectopic Junctional; Tachycardia, Supraventricular	1988
Encainide for resistant supraventricular tachycardia in children: follow-up report. The American journal of cardiology, 1988, Dec-20, Volume: 62, Issue:19 Topics: Administration, Oral; Adolescent; Anilides; Anti-Arrhythmia Agents; Child; Child, Preschool; Drug Therapy, Combination; Encainide; Female; Fetal Diseases; Flecainide; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Pregnancy; Tachycardia, Supraventricular	1988
Aggravation of ventricular arrhythmia. A drug-induced complication. Drugs, 1985, Volume: 29 Suppl 4 Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disopyramide; Drug Evaluation; Electrocardiography; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
[Anti-arrhythmia agents (I): Quinidine, procainamide, disopyramide, encainide, propafenone and flecainide]. Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:11 Topics: Anilides; Anti-Arrhythmia Agents; Disopyramide; Encainide; Flecainide; Humans; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine	1985
New drugs in the management of ventricular arrhythmias. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Drug Interactions; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1984
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
The clinical pharmacology of lidocaine congeners--review of encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Benzeneacetamides; Encainide; Flecainide; Humans; Kinetics; Lidocaine; Piperidines; Tocainide	1984
The use of tocainide, encainide, lorcainide and flecainide for supraventricular arrhythmias. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Benzeneacetamides; Encainide; Flecainide; Heart Atria; Humans; Lidocaine; Piperidines; Tachycardia; Tocainide; Wolff-Parkinson-White Syndrome	1984
Efficacy of type 1C antiarrhythmic agents for treatment of resistant atrial fibrillation. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:12 Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Encainide; Female; Flecainide; Heart Rate; Humans; Male; Middle Aged; Procainamide; Propafenone; Quinidine; Recurrence; Retrospective Studies	1993
Efficacy and safety of combination therapy with amiodarone and type I agents for treatment of inducible ventricular tachycardia. Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:4 Pt 1 Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Drug Therapy, Combination; Electrocardiography; Encainide; Female; Flecainide; Humans; Male; Mexiletine; Middle Aged; Prospective Studies; Stroke Volume; Tachycardia, Ventricular	1993
Efficacy of class 1C antiarrhythmic agents in patients with inducible ventricular tachycardia refractory to therapy with class 1A antiarrhythmic drugs. Journal of clinical pharmacology, 1993, Volume: 33, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Benzeneacetamides; Electric Stimulation; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Piperidines; Quinidine; Retrospective Studies; Stroke Volume; Tachycardia, Ventricular	1993
Effects of flecainide, encainide, and clofilium on ventricular refractory period extension by transcardiac shocks. Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Dogs; Electric Countershock; Encainide; Flecainide; Heart Conduction System; Quaternary Ammonium Compounds; Refractory Period, Electrophysiological; Time Factors; Ventricular Fibrillation; Ventricular Function	1996
Impact of the Food and Drug Administration approval of flecainide and encainide on coronary artery disease mortality: putting "Deadly Medicine" to the test. The American journal of cardiology, 1997, Jan-01, Volume: 79, Issue:1 Topics: Anti-Arrhythmia Agents; Coronary Disease; Drug Approval; Drug Utilization; Encainide; Evaluation Studies as Topic; Flecainide; Humans; Linear Models; Practice Patterns, Physicians'; Survival Analysis; United States; United States Food and Drug Administration; Ventricular Premature Complexes	1997
ST segment elevation induced by class IC antiarrhythmic agents: underlying electrophysiologic mechanisms and insights into drug-induced proarrhythmia. Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:11 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiomyopathy, Dilated; Electrocardiography; Electrophysiology; Encainide; Flecainide; Humans; Male; Middle Aged; Sodium Channel Blockers; Ventricular Fibrillation	1998
A critical appraisal of the cardiac arrhythmia suppression trial (CAST). Applied cardiopulmonary pathophysiology : ACP, 1991, Volume: 4, Issue:1 Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Encainide; Flecainide; Humans; Imipramine; Moricizine; Multicenter Studies as Topic; Pilot Projects; Randomized Controlled Trials as Topic; Risk Factors	1991
[Caution in therapy of ventricular extrasystole. Staying safe with electrolytes]. MMW Fortschritte der Medizin, 2002, Aug-22, Volume: 144, Issue:33-34 Topics: Anti-Arrhythmia Agents; Aspartic Acid; Cardiac Complexes, Premature; Cause of Death; Drug Combinations; Encainide; Flecainide; Humans; Myocardial Infarction; Potassium; Randomized Controlled Trials as Topic; Survival Rate; Treatment Outcome	2002