flecainide has been researched along with e 4031 in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (64.71) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keserü, GM | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Jia, L; Sun, H | 1 |
| Sen, S; Sinha, N | 1 |
| Arita, M; Kiyosue, T; Sato, T; Wu, B | 1 |
| Sugimoto, T; Yamashita, T | 1 |
| Inoue, H; Nozaki, A; Sugimoto, T; Usui, M; Yamashita, T | 1 |
| Inoue, H; Nozaki, A; Sugimoto, T; Yamashita, T | 1 |
| Colatsky, TJ; Follmer, CH | 1 |
| Ajiki, K; Inoue, H; Iwasawa, K; Murakawa, Y; Oikawa, N; Omata, M; Sezaki, K; Usui, M; Yamashita, T | 1 |
| Asayama, J; Inoue, D; Inoue, M; Ishibashi, K; Nakagawa, M; Sakai, R; Shirayama, T | 1 |
| Inoue, H; Saihara, S; Sugimoto, T; Usui, M | 1 |
| Katoh, H; Mitamura, H; Ogawa, S | 1 |
| Hayashi, Y; Kamibayashi, T; Kawabata, K; Sumikawa, K; Takada, K; Yamatodani, A; Yoshiya, I | 1 |
| Kubota, I; Tachibana, H; Tomoike, H; Watanabe, T; Yamaki, M; Yamauchi, S | 1 |
| Hayashi, Y; Ito, I; Iwasaki, M; Kamibayashi, T; Kawai, Y; Mashimo, T; Takada, K; Yamatodani, A | 1 |
| Grunnet, M; Larsen, AP; Olesen, SP; Poelzing, S | 1 |
17 other study(ies) available for flecainide and e 4031
| Article | Year |
|---|---|
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs.
Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Dinitrophenols; Disopyramide; Flecainide; Glyburide; Guinea Pigs; Heart Ventricles; Imidazoles; Lidocaine; Mexiletine; Myocardium; Piperidines; Potassium; Procainamide; Pyridines | 1992 |
[Medical management of arrhythmias; newer antiarrhythmic drugs].
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Chlorobenzenes; Flecainide; Humans; Membrane Potentials; Moricizine; Piperidines; Propylamines; Pyridines; Sodium Channels | 1991 |
Antiarrhythmic drugs preferentially produce conduction block at the area of slow conduction in the re-entrant circuit of canine atrial flutter: comparative study of disopyramide, flecainide, and E-4031.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Disopyramide; Dogs; Flecainide; Heart Conduction System; Piperidines; Pyridines | 1991 |
Effects of antiarrhythmic drugs on canine atrial flutter due to reentry: role of prolongation of refractory period and depression of conduction to excitable gap.
Topics: Animals; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artificial; Disopyramide; Dogs; Electrocardiography; Flecainide; Heart Conduction System; Piperidines; Propafenone; Pyridines; Refractory Period, Electrophysiological | 1991 |
Block of delayed rectifier potassium current, IK, by flecainide and E-4031 in cat ventricular myocytes.
Topics: Animals; Cats; Electric Conductivity; Flecainide; Heart; Heart Ventricles; Myocardium; Osmolar Concentration; Piperidines; Potassium; Pyridines | 1990 |
Shock-induced refractory period extension and pharmacologic modulation of defibrillation threshold.
Topics: Animals; Anti-Arrhythmia Agents; Disopyramide; Dogs; Electric Countershock; Electric Stimulation; Flecainide; Heart; Infusions, Intravenous; Piperidines; Pyridines; Reproducibility of Results | 1994 |
Effects of E-4031 on atrial fibrillation threshold in guinea pig atria: comparative study with class I antiarrhythmic drugs.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Disopyramide; Electric Stimulation; Female; Flecainide; Guinea Pigs; Heart Atria; Heart Conduction System; In Vitro Techniques; Lidocaine; Male; Piperidines; Procainamide; Pyridines; Refractory Period, Electrophysiological | 1994 |
Antifibrillatory effects of class III antiarrhythmic drugs: comparative study with flecainide.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Bretylium Compounds; Dogs; Electric Stimulation; Flecainide; Heart Conduction System; Piperidines; Pyridines; Sotalol; Ventricular Fibrillation | 1993 |
Effect of E-4031, a new class III antiarrhythmic drug, on reentrant ventricular arrhythmias: comparison with conventional class I drugs.
Topics: Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Disease Models, Animal; Disopyramide; Dogs; Electrophysiology; Flecainide; Myocardial Infarction; Piperidines; Potassium Channel Blockers; Pyridines; Tachycardia, Ventricular | 1993 |
Comparative efficacy of antiarrhythmic agents in preventing halothane-epinephrine arrhythmias in rats.
Topics: Amiodarone; Anesthesia, Inhalation; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Epinephrine; Flecainide; Halothane; Isoflurane; Lidocaine; Male; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Verapamil | 1993 |
Intracoronary flecainide induces ST alternans and reentrant arrhythmia on intact canine heart: A role of 4-aminopyridine-sensitive current.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Disopyramide; Dogs; Electrocardiography; Flecainide; Injections; Lidocaine; Piperidines; Pyridines; Sodium Channels; Ventricular Fibrillation; Verapamil | 1999 |
Diabetes mellitus reduces the antiarrhythmic effect of ion channel blockers.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Diabetes Mellitus; Diabetes Mellitus, Experimental; Epinephrine; Flecainide; Halothane; Ion Channels; Male; Piperidines; Potassium Channel Blockers; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Verapamil | 2006 |
Pharmacological activation of IKr impairs conduction in guinea pig hearts.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Ether-A-Go-Go Potassium Channels; Flecainide; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Male; Perfusion; Phenylurea Compounds; Piperidines; Potassium; Potassium Channel Blockers; Pyridines; Sodium Channel Blockers; Tetrazoles; Time Factors; Voltage-Sensitive Dye Imaging | 2010 |