flecainide and cifenline

flecainide has been researched along with cifenline in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19904 (12.12)18.7374
1990's17 (51.52)18.2507
2000's11 (33.33)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Arita, M; Kiyosue, T; Sato, T; Wu, B1
Kato, R; Koide, M; Miyahara, T; Sotobata, I; Toyama, J; Ukai, M; Yasui, S; Yokota, M1
Vaughan Williams, EM1
Kühlkamp, V; Risler, T; Schmid, F; Seipel, L1
Aupetit, JF; Faucon, G; Gerentes-Chassagne, I; Larbre, JP; Loufoua-Moundanga, J; Timour, Q1
Aupetit, JF; Faucon, G; Gerentes-Chassagne, I; Kioueh, I; Loufoua-Moundanga, J; Timour, Q1
Bajolet, A; Chabert, JP; Chapoutot, L; Ehrhard, V; Laudinat, JM; Metivet, F; Metz, D; Pollet, E; Taupin, JM1
Somberg, J1
Baudouy, M; Camous, JP; Gibelin, P; Ichai, C; Meyer, P; Morand, P; Varenne, A1
Touboul, P1
Atallah, G; Kirkorian, G; Moleur, P; Touboul, P1
Babuty, D; D'Hautefeuille, B; Mycinsky, C; Peraudeau, P; Pruvost, P; Scheck, F1
Lüderitz, B; Manz, M1
Aupetit, JF; Faucon, G; Kioueh, I; Larbre, JP; Lopez, M; Loufoua-Moundanga, J; Timour, Q1
Aouate, P; Benassar, A; Fontaine, G; Frank, R; Jacquemin, M; Laborde, JP; Tageddine, R; Tonet, J; Turlure, A1
Arita, M; Kiyosue, T; Sato, T; Wang, DW1
Babuty, D; Brembilla-Perrot, B; Breuillac, JC; Fauchier, JP; Funck, F; Garnier, LF; Maison-Blanche, P; Medvedowsky, JL; Peraudeau, P; Rouesnel, P; Scheck, F1
Mahmood, I1
Beurrier, D; Brembilla-Perrot, B; Danchin, N; Houplon, P; Jacquemin, L; Louis, P; Terrier de la Chaise, A1
Adamantidis, M; Cardinal, R; Delfaut, P; Dupuis, B; Kacet, S; Klug, D; Lacroix, D1
Allessie, MA; Dorland, R; Wijffels, MC1
Allessie, MA; Dorland, R; Mast, F; Wijffels, MC1
Caron, J; Defebvre, L; Destée, A; Devos, D1
Imai, H; Matoba, Y; Nakagawa, M; Shiraishi, H; Shirayama, T; Yoshida, S1
Abo el Makarem, Y; Brembilla-Perrot, B; Claudon, O; Courtelour, JM; Houriez, P; Makarem, E; Suty-Selton, C; Vancon, AC; Yassine, M1
Allessie, MA; Ausma, J; Blaauw, Y; Duytschaever, M; Eijsbouts, S; Schotten, U1
Anderson, ME1
Furukawa, T; Hachiya, H; Higuchi, K; Hirao, K; Isobe, M; Kawabata, M; Okada, H; Sasaki, T1
Aoyama, H; Enomoto, M; Hirayama, A; Imai, S; Kushiro, T; Saito, F; Takase, H; Yagi, H; Yamaji, S; Yokoyama, K1

Reviews

6 review(s) available for flecainide and cifenline

ArticleYear
Classifying antiarrhythmic actions: by facts or speculation.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:11

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Encainide; Flecainide; Heart; Humans; Imidazoles

1992
[Comparative study of cibenzoline and flecainide administered via an intravenous route in reducing auricular arrhythmia].
    Annales de cardiologie et d'angeiologie, 1990, Volume: 39, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Flecainide; Humans; Imidazoles; Injections, Intravenous; Injections, Jet; Male; Middle Aged

1990
Antiarrhythmic drug therapy. Recent advances and current status.
    Cardiology, 1985, Volume: 72, Issue:5-6

    Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil

1985
[New antiarrythmic drugs: mexiletine, tocainide, lorcainide, encainide, flecainide, propafenone, cipralan, sotalol].
    Annales de cardiologie et d'angeiologie, 1982, Volume: 31, Issue:7

    Topics: Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Sotalol; Tocainide

1982
Supraventricular tachycardia and pre-excitation syndromes: pharmacological therapy.
    European heart journal, 1993, Volume: 14 Suppl E

    Topics: Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Disopyramide; Flecainide; Humans; Imidazoles; Pre-Excitation Syndromes; Propafenone; Quinidine; Sotalol; Tachycardia, Paroxysmal; Tachycardia, Supraventricular; Verapamil

1993
[Supraventricular tachycardia with wide QRS complexes during Vaughan-Williams class I anti-arrhythmic treatment. Diagnostic and therapeutic implications].
    Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Heart Rate; Humans; Imidazoles; Male; Middle Aged; Propafenone; Tachycardia, Supraventricular

1995

Trials

4 trial(s) available for flecainide and cifenline

ArticleYear
Randomized comparison of flecainide and cibenzoline in the conversion of atrial fibrillation.
    International journal of cardiology, 1991, Volume: 31, Issue:1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chi-Square Distribution; Female; Flecainide; Follow-Up Studies; Humans; Imidazoles; Male; Middle Aged; Random Allocation; Recurrence

1991
Cibenzoline versus flecainide in the prevention of paroxysmal atrial arrhythmias: a double-blind randomized study.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:5

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Double-Blind Method; Drug Tolerance; Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Female; Flecainide; Follow-Up Studies; Humans; Imidazoles; Male; Middle Aged; Physical Examination; Recurrence

1995
[Comparative study of cibenzoline and flecainide by oral route for preventing recurrence of paroxysmal atrial tachyarrhythmias].
    Annales de cardiologie et d'angeiologie, 1997, Volume: 46, Issue:2

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Double-Blind Method; Flecainide; Humans; Imidazoles; Male; Middle Aged; Recurrence

1997
Use of bepridil in combination with Ic antiarrhythmic agent in converting persistent atrial fibrillation to sinus rhythm.
    Circulation journal : official journal of the Japanese Circulation Society, 2008, Volume: 72, Issue:5

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Natriuretic Factor; Bepridil; Drug Therapy, Combination; Electrocardiography; Female; Flecainide; Follow-Up Studies; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Natriuretic Peptide, Brain; Sinoatrial Node; Treatment Outcome

2008

Other Studies

23 other study(ies) available for flecainide and cifenline

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Blockade of 2,4-dinitrophenol induced ATP sensitive potassium current in guinea pig ventricular myocytes by class I antiarrhythmic drugs.
    Cardiovascular research, 1992, Volume: 26, Issue:11

    Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Dinitrophenols; Disopyramide; Flecainide; Glyburide; Guinea Pigs; Heart Ventricles; Imidazoles; Lidocaine; Mexiletine; Myocardium; Piperidines; Potassium; Procainamide; Pyridines

1992
[Pharmacokinetics and pharmacodynamics of class I antiarrhythmic agents after a single oral administration].
    Japanese circulation journal, 1992, Volume: 56 Suppl 5

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Aprindine; Flecainide; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone

1992
[Arrhythmogenic risk of antiarrhythmic drugs: study with class Ic drugs during myocardial ischemia].
    Bulletin de l'Academie nationale de medecine, 1991, Volume: 175, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Coronary Disease; Disease Models, Animal; Flecainide; Imidazoles; Injections, Intravenous; Propafenone; Swine

1991
Class Ic antiarrhythmic drugs and myocardial ischaemia: study in the pig heart in situ.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 343, Issue:6

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Blood Pressure; Coronary Disease; Coronary Vessels; Female; Flecainide; Heart Conduction System; Heart Rate; Imidazoles; Male; Propafenone; Swine; Ventricular Fibrillation

1991
[Treatment of poisoning caused by new anti-arrhythmia agents (cibenzoline, flecainide and propafenone)].
    Presse medicale (Paris, France : 1983), 1987, Dec-05, Volume: 16, Issue:41

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Flecainide; Humans; Imidazoles; Lactates; Lactic Acid; Male; Middle Aged; Propafenone

1987
[New class I anti-arrhythmia agents].
    La Revue du praticien, 1986, Nov-21, Volume: 36, Issue:53

    Topics: Anti-Arrhythmia Agents; Bepridil; Flecainide; Humans; Imidazoles; Kinetics; Propafenone; Pyrrolidines

1986
Arrhythmogenicity of antiarrhythmic drugs and intraventricular conduction disorders: possible aggravation by myocardial ischemia--study in the porcine in situ heart.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Electrocardiography; Female; Flecainide; Heart Conduction System; Heart Rate; Imidazoles; Male; Myocardial Ischemia; Propafenone; Swine

1993
Comparison of the effects of class I anti-arrhythmic drugs, cibenzoline, mexiletine and flecainide, on the delayed rectifier K+ current of guinea-pig ventricular myocytes.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:5

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Flecainide; Guinea Pigs; Imidazoles; Ion Transport; Mexiletine; Patch-Clamp Techniques; Potassium; Ventricular Function

1996
Prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: a critical view.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:6

    Topics: Acebutolol; Administration, Oral; Adult; Aged; Amiloride; Anti-Arrhythmia Agents; Anti-Infective Agents; Area Under Curve; Atenolol; Biological Availability; Diuretics; Enoxacin; Flecainide; Histamine H2 Antagonists; Humans; Imidazoles; Kidney; Middle Aged; Ranitidine; Renal Insufficiency; Tiopronin

1997
[Can 1/1 atrial flutter be foreseen by class I anti-arrhythmics?].
    Archives des maladies du coeur et des vaisseaux, 1997, Volume: 90, Issue:7

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Flutter; Disopyramide; Electrocardiography; Female; Flecainide; Heart Conduction System; Humans; Imidazoles; Male; Middle Aged; Predictive Value of Tests; Propafenone; Quinidine; Risk Factors

1997
Differential effects of quinidine, flecainide, and cibenzoline on anisotropic conduction in the isolated porcine heart.
    Journal of cardiovascular electrophysiology, 1998, Volume: 9, Issue:1

    Topics: Action Potentials; Animals; Anisotropy; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiac Pacing, Artificial; Female; Flecainide; Heart; Heart Conduction System; Imidazoles; In Vitro Techniques; Pericardium; Potassium Channel Blockers; Quinidine; Swine

1998
Pharmacologic cardioversion of chronic atrial fibrillation in the goat by class IA, IC, and III drugs: a comparison between hydroquinidine, cibenzoline, flecainide, and d-sotalol.
    Journal of cardiovascular electrophysiology, 1999, Volume: 10, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Disease Models, Animal; Electrocardiography; Flecainide; Follow-Up Studies; Goats; Heart Conduction System; Imidazoles; Injections, Intravenous; Quinidine; Secondary Prevention; Sotalol; Treatment Outcome

1999
Widening of the excitable gap during pharmacological cardioversion of atrial fibrillation in the goat: effects of cibenzoline, hydroquinidine, flecainide, and d-sotalol.
    Circulation, 2000, Jul-11, Volume: 102, Issue:2

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Flecainide; Goats; Heart Conduction System; Imidazoles; Quinidine; Sotalol

2000
Choreic movements induced by cibenzoline: an Ic class antiarrhythmic effect?
    Movement disorders : official journal of the Movement Disorder Society, 2000, Volume: 15, Issue:5

    Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chorea; Dopamine Antagonists; Dyskinesia, Drug-Induced; Dystonia; Female; Flecainide; Humans; Imidazoles; Ion Channels; Pacemaker, Artificial; Potassium; Remission Induction; Sulpiride

2000
Atrial fibrillation threshold predicted long-term efficacy of pharmacological treatment of patients without structural heart disease.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2002, Volume: 4, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Aprindine; Atrial Fibrillation; Disopyramide; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Treatment Outcome

2002
[Can the supraventricular proarrhythmic effects of class 1C antiarrhythmic drugs be prevented with the association of beta blockers?].
    Annales de cardiologie et d'angeiologie, 2000, Volume: 49, Issue:8

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Flutter; Female; Flecainide; Humans; Imidazoles; Male; Middle Aged

2000
Serial cardioversion by class IC Drugs during 4 months of persistent atrial fibrillation in the goat.
    Journal of cardiovascular electrophysiology, 2006, Volume: 17, Issue:6

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Dose-Response Relationship, Drug; Electrocardiography; Female; Flecainide; Goats; Heart Conduction System; Imidazoles; Time Factors

2006
Too little, too late: chasing atrial fibrillation with sodium channel antagonists.
    Journal of cardiovascular electrophysiology, 2006, Volume: 17, Issue:6

    Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Flecainide; Heart Conduction System; Humans; Imidazoles; Potassium Channel Blockers; Sodium Channel Blockers; Time Factors

2006
Clinical and electrophysiological characteristics of patients having atrial flutter with 1:1 atrioventricular conduction.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2008, Volume: 10, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Case-Control Studies; Catheter Ablation; Electrocardiography; Electrophysiologic Techniques, Cardiac; Female; Flecainide; Heart Atria; Heart Conduction System; Heart Ventricles; Humans; Imidazoles; Lidocaine; Male; Middle Aged; Retrospective Studies; Risk Factors

2008