Page last updated: 2024-08-21

flavone and naringenin

flavone has been researched along with naringenin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's3 (12.00)18.2507
2000's6 (24.00)29.6817
2010's13 (52.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Fernandes, E; Freitas, M; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Cabrita, EJ; Fernandes, E; Freitas, M; Marques, MM; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Alunda, JM; Baptista, C; Behrens, B; Bifeld, E; Borsari, C; Clos, J; Cordeiro-da-Silva, A; Corral, MJ; Costantino, L; Costi, MP; Dello Iacono, L; Di Pisa, F; Eick, J; Ellinger, B; Ferrari, S; Gribbon, P; Gul, S; Henrich, S; Jiménez-Antón, MD; Keminer, O; Kohler, M; Kuzikov, M; Landi, G; Luciani, R; Mangani, S; Pellati, F; Poehner, I; Pozzi, C; Reinshagen, J; Santarem, N; Tait, A; Tejera Nevado, P; Torrado, J; Trande, M; Wade, RC; Witt, G; Wolf, M1
Kang, Y; Kim, BG; Kim, S; Lee, Y; Yoon, Y1
Guo, CL; Guo, SJ; Jiang, B; Li, N; Li, XQ; Shi, DY; Wang, LJ1
Chang, CJ; Geahlen, RL1
Chen, K; Cheng, YC; Hu, CQ; Kilkuskie, RE; Lee, KH; Shi, Q1
Augereau, JM; Billon, M; Gleye, J; Herbert, JM; Lale, A; Leconte, M1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Kirchmair, J; Laggner, C; Langer, T; Nashev, LG; Odermatt, A; Schuster, D; Wolber, G1
Carpinella, MC; Diaz Napal, GN; Palacios, SM1
Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H1
Muftuoglu, Y; Mustata, G1
Estrada-Soto, S; Figueroa, M; Hernández-Abreu, O; Ibarra-Barajas, M; Navarrete-Vázquez, G; Torres-Piedra, M1
Hyun, J; Koh, D; Lee, YH; Lim, Y; Shin, SY; Woo, Y; Yong, Y1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Akram, M; Atanasov, AG; Ateba, SB; Bachmann, F; Davis, RA; Engeli, RT; Krenn, L; Leugger, S; Njamen, D; Odermatt, A; Schuster, D; Stuppner, H; Temml, V; Vuorinen, A; Waltenberger, B1
Fernandes, E; Fernandes, PA; Freitas, M; Oliveira, A; Proença, C; Ramos, MJ; Ribeiro, D; Silva, AMS; Sousa, JLC1
Fong, J; Korobkova, EA; Maran, U; Oja, M; Rice, M; Samuels, K; Sapse, AM; Williams, AK; Wong, B1
Hii, CS; Howell, SL1
Akiya, T; Nishizawa, H; Sato, S; Suzuki, T1
Nozawa, A; Tozawa, Y; Yamamoto, T; Yun, CS1
Mahalakshmi, P; Sabarinathan, D; Vanisree, AJ1
Bredebach, M; Martens, S; Matern, U1
Modelli, A; Pshenichnyuk, SA1

Reviews

2 review(s) available for flavone and naringenin

ArticleYear
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Structure-Activity Relationship

2018
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992

Other Studies

23 other study(ies) available for flavone and naringenin

ArticleYear
Modulation of human neutrophils' oxidative burst by flavonoids.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Flavonoids; Humans; Luminescent Measurements; Molecular Structure; Neutrophils; Oxidation-Reduction

2013
Inhibition of LOX by flavonoids: a structure-activity relationship study.
    European journal of medicinal chemistry, 2014, Jan-24, Volume: 72

    Topics: Dose-Response Relationship, Drug; Flavonoids; Glycine max; Humans; Leukotriene B4; Lipoxygenase; Molecular Structure; Neutrophils; Structure-Activity Relationship

2014
Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
    Journal of medicinal chemistry, 2016, 08-25, Volume: 59, Issue:16

    Topics: Animals; Biological Products; Cell Line; Dose-Response Relationship, Drug; Flavonols; Humans; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2016
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Binding Sites; Flavones; Flavonoids; Flavonols; Liposomes; Molecular Docking Simulation; Phosphatidylinositol Phosphates; Pleckstrin Homology Domains; Protein Binding; Quantitative Structure-Activity Relationship

2017
Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids.
    Journal of natural products, 1994, Volume: 57, Issue:1

    Topics: Antiviral Agents; Cells, Cultured; Flavonoids; Galactosides; HIV-1; Humans; Mass Spectrometry; Medicine, Chinese Traditional; Plants, Medicinal; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Virus Replication; Zidovudine

1994
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
    Journal of natural products, 1996, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Blood Coagulation; Cell Adhesion; Endotoxins; Flavonoids; Humans; In Vitro Techniques; Interleukin-1; Molecular Sequence Data; Monocytes

1996
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: 17-Hydroxysteroid Dehydrogenases; Catalysis; Cell Line; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavonoids; Humans; Models, Chemical; Small Molecule Libraries

2008
Antifeedant activity of ethanolic extract from Flourensia oolepis and isolation of pinocembrin as its active principle compound.
    Bioresource technology, 2009, Volume: 100, Issue:14

    Topics: Animals; Asteraceae; Biological Assay; Biotechnology; Ethanol; Flavanones; Host-Parasite Interactions; Insecticides; Models, Chemical; Pest Control, Biological; Plant Extracts; Plant Leaves; Plant Oils; Quercetin; Spodoptera

2009
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship

2009
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
    Bioorganic & medicinal chemistry letters, 2010, May-15, Volume: 20, Issue:10

    Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship

2010
Vasorelaxant effect of flavonoids through calmodulin inhibition: Ex vivo, in vitro, and in silico approaches.
    Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1

    Topics: Animals; Aorta; Calmodulin; Dose-Response Relationship, Drug; Flavonoids; In Vitro Techniques; Models, Molecular; Rats; Rats, Wistar; Vasodilator Agents

2011
Relationship between the structures of flavonoids and their NF-κB-dependent transcriptional activities.
    Bioorganic & medicinal chemistry letters, 2011, Oct-15, Volume: 21, Issue:20

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Flavonoids; Humans; Models, Molecular; NF-kappa B; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2011
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: 17-Hydroxysteroid Dehydrogenases; Biological Products; Enzyme Inhibitors; Etiocholanolone; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Testosterone

2017
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.
    Journal of natural products, 2020, 05-22, Volume: 83, Issue:5

    Topics: Drug Design; Enzyme Inhibitors; Flavonoids; Fructose; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Liver; Molecular Structure

2020
A role of flavonoids in cytochrome c-cardiolipin interactions.
    Bioorganic & medicinal chemistry, 2021, 03-01, Volume: 33

    Topics: Cardiolipins; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship

2021
Effects of flavonoids on insulin secretion and 45Ca2+ handling in rat islets of Langerhans.
    The Journal of endocrinology, 1985, Volume: 107, Issue:1

    Topics: Animals; Calcium; Catechin; Flavanones; Flavones; Flavonoids; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Quercetin; Rats; Rats, Inbred Strains

1985
Total synthesis of three naturally occurring 6,8-di-C-glycosylflavonoids: phloretin, naringenin, and apigenin bis-C-beta-D-glucosides.
    Carbohydrate research, 2006, Jun-12, Volume: 341, Issue:8

    Topics: Flavanones; Flavones; Flavonoids; Glucosides; Hydrolysis; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phloretin

2006
Expression of parsley flavone synthase I establishes the flavone biosynthetic pathway in Arabidopsis thaliana.
    Bioscience, biotechnology, and biochemistry, 2008, Volume: 72, Issue:4

    Topics: Apigenin; Arabidopsis; Cloning, Molecular; Flavanones; Flavones; Flavonoids; Gene Expression Regulation, Plant; Mixed Function Oxygenases; Petroselinum; Plants, Genetically Modified

2008
Naringenin promote apoptosis in cerebrally implanted C6 glioma cells.
    Molecular and cellular biochemistry, 2010, Volume: 345, Issue:1-2

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Cerebrum; Estrogen Antagonists; Flavanones; Flavones; Gene Expression Regulation, Neoplastic; Glioma; Microscopy, Electron, Transmission; Neoplasms, Experimental; Rats

2010
Three 2-oxoglutarate-dependent dioxygenase activities of Equisetum arvense L. forming flavone and flavonol from (2S)-naringenin.
    Phytochemistry, 2011, Volume: 72, Issue:7

    Topics: Dioxygenases; Equisetum; Flavanones; Flavones; Flavonols; Gene Expression Regulation, Plant; Hydrogen-Ion Concentration; Ketoglutaric Acids; Mixed Function Oxygenases; Substrate Specificity; Temperature

2011
Gas-phase dissociative electron attachment to flavonoids and possible similarities to their metabolic pathways.
    Physical chemistry chemical physics : PCCP, 2013, Feb-07, Volume: 15, Issue:5

    Topics: Chromones; Electrons; Flavanones; Flavones; Flavonoids; Gases; Hydrogen; Quercetin; Thermodynamics

2013