Compounds > flavone
Page last updated: 2024-08-21

flavone and luteolin

flavone has been researched along with luteolin in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19903 (8.11)18.7374
1990's3 (8.11)18.2507
2000's5 (13.51)29.6817
2010's21 (56.76)24.3611
2020's5 (13.51)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Chen, K; Cheng, YC; Hu, CQ; Kilkuskie, RE; Lee, KH; Shi, Q1
Augereau, JM; Billon, M; Gleye, J; Herbert, JM; Lale, A; Leconte, M1
Komai, K; Morimoto, M; Nakano, A; Nakano, S; Ozaki, T; Tanimoto, K1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H1
Alcaro, S; Bolasco, A; Chimenti, F; Chimenti, P; Cirilli, R; Ferretti, R; Fioravanti, R; Orallo, F; Ortuso, F; Rossi, F; Sanna, ML; Secci, D; Yáñez, M1
Kogami, Y; Matsuda, H; Nakamura, S; Sugiyama, T; Ueno, T; Yoshikawa, M1
Fallarero, A; Haikarainen, T; Lehtiö, L; Narwal, M; Vuorela, PM1
Fernandes, E; Freitas, M; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Cabrita, EJ; Fernandes, E; Freitas, M; Marques, MM; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM1
Fernandes, E; Freitas, M; Ribeiro, D; Silva, AM; Tomé, SM1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Alunda, JM; Baptista, C; Behrens, B; Bifeld, E; Borsari, C; Clos, J; Cordeiro-da-Silva, A; Corral, MJ; Costantino, L; Costi, MP; Dello Iacono, L; Di Pisa, F; Eick, J; Ellinger, B; Ferrari, S; Gribbon, P; Gul, S; Henrich, S; Jiménez-Antón, MD; Keminer, O; Kohler, M; Kuzikov, M; Landi, G; Luciani, R; Mangani, S; Pellati, F; Poehner, I; Pozzi, C; Reinshagen, J; Santarem, N; Tait, A; Tejera Nevado, P; Torrado, J; Trande, M; Wade, RC; Witt, G; Wolf, M1
Abramić, M; Agić, D; Bešlo, D; Brkić, H; Karačić, Z; Lisjak, M; Špoljarević, M; Tomić, S1
Kang, Y; Kim, BG; Kim, S; Lee, Y; Yoon, Y1
An, JY; Kim, NJ; Kim, SW; Lee, HH; Lee, J; Lee, KT; Park, JS; Shin, JS; Son, SH; Yoo, HS; Yu, J1
Dutour, R; Poirier, D1
Guo, CL; Guo, SJ; Jiang, B; Li, N; Li, XQ; Shi, DY; Wang, LJ1
Jin, YS1
Fernandes, E; Fernandes, PA; Freitas, M; Oliveira, A; Proença, C; Ramos, MJ; Ribeiro, D; Silva, AMS; Sousa, JLC1
Fong, J; Korobkova, EA; Maran, U; Oja, M; Rice, M; Samuels, K; Sapse, AM; Williams, AK; Wong, B1
Boué, SM; Carter-Wientjes, CH; Cleveland, TE; Shih, BY1
GLOGGENGIESSER, F; HORHAMMER, L; WAGNER, H1
DHINGRA, HS; HORHAMMER, L; WAGNER, H1
HOERHAMMER, L; LEEB, W; WAGNER, H1
Chen, ZT; Liang, YF; Liu, LH1
Panagiotidou, S; Patel, AB; Theoharides, TC; Weng, Z1
Chang, CY; Chen, TH; Lee, KR; Lin, CH; Lin, HJ; Wan, L1
Abbadi, J; Abu-Lafi, S; Al-Rimawi, F; Alamarneh, AAA; Odeh, I; Sawahreh, RA1
Dhakal, D; Pandey, RP; Parajuli, P; Shrestha, A; Sohng, JK1
Bao, YR; Fan, JX; Li, TJ; Meng, XS; Wang, S1
McCullagh, M; Pereira, CAM; Yariwake, JH1
Hnitecka, A; Szopa, J; Szperlik, J; Zuk, M1
Ahmed, ME; Chandrasekaran, PN; Govindarajan, R; Iyer, SS; Kempuraj, D; Kempuraj, DD; Raikwar, SP; Selvakumar, GP; Thangavel, R; Zaheer, A; Zaheer, SA1
Huang, DJ; Sun, HJ; Sun, ZQ; Wu, ZY; Xin, Y; Ye, L1
Song, W; Sun, X; Wang, X; Wei, J; Wu, Z; Xue, X; Zhang, C; Zhang, Z; Zhao, J; Zheng, D1

Reviews

5 review(s) available for flavone and luteolin

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992
Inhibitors of cytochrome P450 (CYP) 1B1.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship

2017
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Structure-Activity Relationship

2018
Recent advances in natural antifungal flavonoids and their derivatives.
    Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19

    Topics: Antifungal Agents; Biological Products; Flavonoids; Fungi; Humans; Mycoses

2019
Neuroprotective effects of flavone luteolin in neuroinflammation and neurotrauma.
    BioFactors (Oxford, England), 2021, Volume: 47, Issue:2

    Topics: Brain; Brain Injuries; Brain Injuries, Traumatic; COVID-19; COVID-19 Drug Treatment; Flavones; Humans; Inflammation; Luteolin; Neurons; Neuroprotective Agents; SARS-CoV-2

2021

Other Studies

32 other study(ies) available for flavone and luteolin

ArticleYear
Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids.
    Journal of natural products, 1994, Volume: 57, Issue:1

    Topics: Antiviral Agents; Cells, Cultured; Flavonoids; Galactosides; HIV-1; Humans; Mass Spectrometry; Medicine, Chinese Traditional; Plants, Medicinal; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Virus Replication; Zidovudine

1994
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
    Journal of natural products, 1996, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Blood Coagulation; Cell Adhesion; Endotoxins; Flavonoids; Humans; In Vitro Techniques; Interleukin-1; Molecular Sequence Data; Monocytes

1996
Insect antifeedant activity of flavones and chromones against Spodoptera litura.
    Journal of agricultural and food chemistry, 2003, Jan-15, Volume: 51, Issue:2

    Topics: Animals; Chromones; Eating; Flavonoids; Gnaphalium; Insecticides; Methylation; Spodoptera; Structure-Activity Relationship

2003
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship

2009
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.
    Bioorganic & medicinal chemistry, 2010, Volume: 18, Issue:3

    Topics: Flavanones; Flavones; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Stereoisomerism; Sulfhydryl Compounds

2010
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.
    Bioorganic & medicinal chemistry, 2011, May-01, Volume: 19, Issue:9

    Topics: 3T3-L1 Cells; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; Deoxyglucose; Fatty Acid-Binding Proteins; Flavonoids; Glucose Transporter Type 4; Mice; PPAR gamma; Structure-Activity Relationship

2011
Screening and structural analysis of flavones inhibiting tankyrases.
    Journal of medicinal chemistry, 2013, May-09, Volume: 56, Issue:9

    Topics: Amino Acid Sequence; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavones; Humans; Models, Molecular; Molecular Sequence Data; Protein Conformation; Small Molecule Libraries; Substrate Specificity; Tankyrases

2013
Modulation of human neutrophils' oxidative burst by flavonoids.
    European journal of medicinal chemistry, 2013, Volume: 67

    Topics: Flavonoids; Humans; Luminescent Measurements; Molecular Structure; Neutrophils; Oxidation-Reduction

2013
Inhibition of LOX by flavonoids: a structure-activity relationship study.
    European journal of medicinal chemistry, 2014, Jan-24, Volume: 72

    Topics: Dose-Response Relationship, Drug; Flavonoids; Glycine max; Humans; Leukotriene B4; Lipoxygenase; Molecular Structure; Neutrophils; Structure-Activity Relationship

2014
Synthesis of chlorinated flavonoids with anti-inflammatory and pro-apoptotic activities in human neutrophils.
    European journal of medicinal chemistry, 2014, Oct-30, Volume: 86

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cell Survival; Dose-Response Relationship, Drug; Flavonoids; Humans; Hydrocarbons, Chlorinated; Molecular Structure; Neutrophils; Structure-Activity Relationship

2014
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
    Journal of medicinal chemistry, 2016, 08-25, Volume: 59, Issue:16

    Topics: Animals; Biological Products; Cell Line; Dose-Response Relationship, Drug; Flavonols; Humans; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2016
Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: Experimental and computational approach.
    Chemical biology & drug design, 2017, Volume: 89, Issue:4

    Topics: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Flavonoids; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Principal Component Analysis; Protease Inhibitors; Quantitative Structure-Activity Relationship

2017
Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.
    Bioorganic & medicinal chemistry letters, 2017, 02-01, Volume: 27, Issue:3

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Binding Sites; Flavones; Flavonoids; Flavonols; Liposomes; Molecular Docking Simulation; Phosphatidylinositol Phosphates; Pleckstrin Homology Domains; Protein Binding; Quantitative Structure-Activity Relationship

2017
Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE
    Bioorganic & medicinal chemistry letters, 2017, 06-01, Volume: 27, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Dinoprostone; Flavones; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; RAW 264.7 Cells; Structure-Activity Relationship

2017
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.
    Journal of natural products, 2020, 05-22, Volume: 83, Issue:5

    Topics: Drug Design; Enzyme Inhibitors; Flavonoids; Fructose; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Liver; Molecular Structure

2020
A role of flavonoids in cytochrome c-cardiolipin interactions.
    Bioorganic & medicinal chemistry, 2021, 03-01, Volume: 33

    Topics: Cardiolipins; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship

2021
Identification of flavone aglycones and glycosides in soybean pods by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. A, 2003, Mar-28, Volume: 991, Issue:1

    Topics: Apigenin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Flavones; Flavonoids; Glucosides; Glycine max; Glycosides; Luteolin; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet

2003
[A new glycoside type of flavone series. I. Isolation of luteolin & apigenine glycosides from Polygonum orientale].
    Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1958, Volume: 291/63, Issue:3

    Topics: Cardiac Glycosides; Flavones; Glycosides; Luteolin; Polygonaceae; Polygonum

1958
[A new glycoside-type in the flavone series. 2. Isolation of a second weakly-hydrolyzable luteolin glycoside from the blooms of Spartium junceum L].
    Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1959, Volume: 292/64, Issue:2

    Topics: Cardiac Glycosides; Flavones; Glycosides; Luteolin; Spartium

1959
[On a new type of glycosid of the flavone series. Part 4. Adonivernith, a luteolin-8-hexityl mono-xyloside from Adonis vernalis L].
    Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1960, Volume: 293/65

    Topics: Adonis; Flavones; Glycosides; Luteolin

1960
[Studies on chemical constituents of Ranunculus japonicus].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2008, Volume: 33, Issue:19

    Topics: 1-Butanol; Acetates; Alkanes; Coumarins; Drugs, Chinese Herbal; Ethanol; Flavones; Flavonoids; Furans; Hydroxybenzoates; Luteolin; Ranunculus; Scopoletin; Spectrometry, Mass, Electrospray Ionization

2008
The novel flavone tetramethoxyluteolin is a potent inhibitor of human mast cells.
    The Journal of allergy and clinical immunology, 2015, Volume: 135, Issue:4

    Topics: Antibodies, Anti-Idiotypic; Calcium; Capillary Permeability; Cell Degranulation; Cells, Cultured; Chemokine CCL2; Flavones; Gene Expression Regulation; Hexosaminidases; Humans; Immunoglobulin E; Luteolin; Mast Cells; NF-kappa B; Tumor Necrosis Factors

2015
Flavones inhibit breast cancer proliferation through the Akt/FOXO3a signaling pathway.
    BMC cancer, 2015, Dec-16, Volume: 15

    Topics: Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Female; Flavones; Flow Cytometry; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Luteolin; Proto-Oncogene Proteins c-akt; Real-Time Polymerase Chain Reaction; Signal Transduction

2015
ANALYSIS OF PHENOLIC AND FLAVONOIDS OF WILD
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2017, Volume: 14, Issue:2

    Topics: Antioxidants; Chromatography, High Pressure Liquid; Ephedra; Flavones; Flavonoids; Glycosides; Luteolin; Mass Spectrometry; Oxidation-Reduction; Phenols; Plant Extracts; Polyphenols; Solvents

2017
Biosynthesis of flavone C-glucosides in engineered Escherichia coli.
    Applied microbiology and biotechnology, 2018, Volume: 102, Issue:3

    Topics: Batch Cell Culture Techniques; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Escherichia coli; Fermentation; Flavones; Flavonoids; Gentiana; Glucokinase; Glucosides; Glucosyltransferases; Glycine max; Luteolin; Metabolic Engineering; Phosphoglucomutase; Spectrometry, Mass, Electrospray Ionization; Uridine Diphosphate Glucose

2018
[Study of cancer cell apoptosis induced by Schizonepeta tenuifolia with microfluidic chip technology].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2017, Volume: 52, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apigenin; Apoptosis; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Flavones; Flavonoids; Glucosides; Hesperidin; Lamiaceae; Luteolin; Mass Spectrometry; Microfluidics; Plant Extracts

2017
Use of ion mobility mass spectrometry to enhance cumulative analytical specificity and separation to profile 6-C/8-C-glycosylflavone critical isomer pairs and known-unknowns in medicinal plants.
    Phytochemical analysis : PCA, 2019, Volume: 30, Issue:4

    Topics: Apigenin; Chromatography, High Pressure Liquid; Flavones; Flavonoids; Glucosides; Glycosides; Isomerism; Luteolin; Mass Spectrometry; Passiflora; Phytochemicals; Plant Extracts; Plants, Medicinal

2019
Temporal biosynthesis of flavone constituents in flax growth stages.
    Plant physiology and biochemistry : PPB, 2019, Volume: 142

    Topics: Apigenin; Cellulose; Cytochrome P-450 Enzyme System; Flavones; Flax; Luteolin; Phenols; Real-Time Polymerase Chain Reaction

2019
A Newly Synthesized Flavone from Luteolin Escapes from COMT-Catalyzed Methylation and Inhibits Lipopolysaccharide-Induced Inflammation in RAW264.7 Macrophages via JNK, p38 and NF-κB Signaling Pathways.
    Journal of microbiology and biotechnology, 2022, Jan-28, Volume: 32, Issue:1

    Topics: Amidines; Animals; Anti-Inflammatory Agents; Catalysis; Catechol O-Methyltransferase; Cell Survival; Cytokines; Flavones; Inflammation; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Luteolin; Macrophages; Methylation; Mice; NF-kappa B; Nitric Oxide Synthase Type II; RAW 264.7 Cells; Signal Transduction

2022
Natural variation of ZmCGT1 is responsible for isoorientin accumulation in maize silk.
    The Plant journal : for cell and molecular biology, 2022, Volume: 109, Issue:1

    Topics: Flavones; Genetic Variation; Genome-Wide Association Study; Glycosyltransferases; Luteolin; Metabolome; Plant Leaves; Plant Proteins; Plant Roots; Plant Stems; Zea mays

2022