Page last updated: 2024-08-21

flavone and kaempferol

flavone has been researched along with kaempferol in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's4 (14.29)18.2507
2000's8 (28.57)29.6817
2010's13 (46.43)24.3611
2020's2 (7.14)2.80

Authors

AuthorsStudies
Chang, CJ; Geahlen, RL1
Constantinou, A; Mehta, R; Moon, R; Rao, K; Runyan, C; Vaughan, A1
Augereau, JM; Billon, M; Gleye, J; Herbert, JM; Lale, A; Leconte, M1
Ash, K; Grohmann, K; Manthey, CL; Manthey, JA; Montanari, A1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Autino, JC; Bennardi, DO; Castro, EA; Duchowicz, PR; Romanelli, GP; Vitale, MG1
Kirchmair, J; Laggner, C; Langer, T; Nashev, LG; Odermatt, A; Schuster, D; Wolber, G1
Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H1
Bönisch, H; Haenisch, B; Mayer, R; Müller, CE; Müller, H; Pajeva, IK; Pick, A; Weigt, M; Wiese, M1
Kogami, Y; Matsuda, H; Nakamura, S; Sugiyama, T; Ueno, T; Yoshikawa, M1
Cho, SJ; Choi, CH; Gadhe, CG; Kothandan, G; Madhavan, T1
Duerksen-Hughes, PJ; Filippova, M; Krstenansky, JL; Tungteakkhun, SS; Yuan, CH1
Bicknell, KA; Farrimond, JA; Putnam, SE; Swioklo, S; Watson, KA; Williamson, EM1
Alunda, JM; Baptista, C; Behrens, B; Bifeld, E; Borsari, C; Clos, J; Cordeiro-da-Silva, A; Corral, MJ; Costantino, L; Costi, MP; Dello Iacono, L; Di Pisa, F; Eick, J; Ellinger, B; Ferrari, S; Gribbon, P; Gul, S; Henrich, S; Jiménez-Antón, MD; Keminer, O; Kohler, M; Kuzikov, M; Landi, G; Luciani, R; Mangani, S; Pellati, F; Poehner, I; Pozzi, C; Reinshagen, J; Santarem, N; Tait, A; Tejera Nevado, P; Torrado, J; Trande, M; Wade, RC; Witt, G; Wolf, M1
Abramić, M; Agić, D; Bešlo, D; Brkić, H; Karačić, Z; Lisjak, M; Špoljarević, M; Tomić, S1
Akram, M; Atanasov, AG; Ateba, SB; Bachmann, F; Davis, RA; Engeli, RT; Krenn, L; Leugger, S; Njamen, D; Odermatt, A; Schuster, D; Stuppner, H; Temml, V; Vuorinen, A; Waltenberger, B1
Daidone, G; Maggio, B; Plescia, F; Raffa, D; Raimondi, MV1
Guo, CL; Guo, SJ; Jiang, B; Li, N; Li, XQ; Shi, DY; Wang, LJ1
Jin, YS1
Fernandes, E; Fernandes, PA; Freitas, M; Oliveira, A; Proença, C; Ramos, MJ; Ribeiro, D; Silva, AMS; Sousa, JLC1
Fong, J; Korobkova, EA; Maran, U; Oja, M; Rice, M; Samuels, K; Sapse, AM; Williams, AK; Wong, B1
Nose, K1
Chaudhuri, SK; Kinst-Hori, I; Kubo, I; Kubo, Y; Ogura, T; Sánchez, Y1
Czajka, D; Kroll, J; Rawel, HM; Rohn, S1
Chen, YC; Hsu, FL; Juan, SH; Lin, HY; Shen, SC1
Alexandrakis, M; Boucher, W; Christodoulou, S; Huang, M; Kandere-Grzybowska, K; Kempuraj, D; Letourneau, R; Seretakis, D; Theoharides, TC1
Cao, C; Cao, J; Chen, W; Li, Y; Wang, C; Wang, J; Zhang, X; Zhang, Y; Zhao, X1
Gao, JY; Gong, LM; Li, B; Li, SX; Liu, PA; Liu, QR1

Reviews

4 review(s) available for flavone and kaempferol

ArticleYear
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
    Journal of natural products, 1992, Volume: 55, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases

1992
Recent discoveries of anticancer flavonoids.
    European journal of medicinal chemistry, 2017, Dec-15, Volume: 142

    Topics: Animals; Antineoplastic Agents, Phytogenic; Benzopyrans; Drug Discovery; Flavonoids; Humans; Neoplasms; Plants; Structure-Activity Relationship

2017
Recent progress of the development of dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Hypoglycemic Agents; Molecular Docking Simulation; Structure-Activity Relationship

2018
Recent advances in natural antifungal flavonoids and their derivatives.
    Bioorganic & medicinal chemistry letters, 2019, 10-01, Volume: 29, Issue:19

    Topics: Antifungal Agents; Biological Products; Flavonoids; Fungi; Humans; Mycoses

2019

Other Studies

24 other study(ies) available for flavone and kaempferol

ArticleYear
Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships.
    Journal of natural products, 1995, Volume: 58, Issue:2

    Topics: DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Electrophoresis, Agar Gel; Flavonoids; Hydroxylation; Plasmids; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1995
Ability of different flavonoids to inhibit the procoagulant activity of adherent human monocytes.
    Journal of natural products, 1996, Volume: 59, Issue:3

    Topics: Amino Acid Sequence; Blood Coagulation; Cell Adhesion; Endotoxins; Flavonoids; Humans; In Vitro Techniques; Interleukin-1; Molecular Sequence Data; Monocytes

1996
Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes.
    Journal of natural products, 1999, Volume: 62, Issue:3

    Topics: Citrus; Cyclic AMP; Flavonoids; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

1999
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
QSAR modeling of the interaction of flavonoids with GABA(A) receptor.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:8

    Topics: Binding Sites; Flavonoids; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, GABA-A

2008
Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: 17-Hydroxysteroid Dehydrogenases; Catalysis; Cell Line; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavonoids; Humans; Models, Chemical; Small Molecule Libraries

2008
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship

2009
Structure-activity relationships of flavonoids as inhibitors of breast cancer resistance protein (BCRP).
    Bioorganic & medicinal chemistry, 2011, Mar-15, Volume: 19, Issue:6

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Flavonoids; Humans; Hydrogen Bonding; Models, Molecular; Neoplasm Proteins; Quantitative Structure-Activity Relationship

2011
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.
    Bioorganic & medicinal chemistry, 2011, May-01, Volume: 19, Issue:9

    Topics: 3T3-L1 Cells; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; Deoxyglucose; Fatty Acid-Binding Proteins; Flavonoids; Glucose Transporter Type 4; Mice; PPAR gamma; Structure-Activity Relationship

2011
Docking and 3D-QSAR (quantitative structure activity relationship) studies of flavones, the potent inhibitors of p-glycoprotein targeting the nucleotide binding domain.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B; Binding Sites; Flavones; Humans; Models, Molecular; Molecular Sequence Data; Nucleotides; Quantitative Structure-Activity Relationship; Sequence Homology, Amino Acid

2011
Small molecule inhibitors of the HPV16-E6 interaction with caspase 8.
    Bioorganic & medicinal chemistry letters, 2012, Mar-01, Volume: 22, Issue:5

    Topics: Apoptosis; Caspase 8; Caspase Inhibitors; Fas-Associated Death Domain Protein; Female; Flavones; Flavonols; Host-Pathogen Interactions; Human papillomavirus 16; Humans; Oncogene Proteins, Viral; Papillomavirus Infections; Repressor Proteins; Small Molecule Libraries; Uterine Cervical Neoplasms

2012
Defining Key Structural Determinants for the Pro-osteogenic Activity of Flavonoids.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Cell Differentiation; Flavonoids; Humans; Mesenchymal Stem Cells; Molecular Structure; Osteogenesis; Signal Transduction; Structure-Activity Relationship

2015
Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
    Journal of medicinal chemistry, 2016, 08-25, Volume: 59, Issue:16

    Topics: Animals; Biological Products; Cell Line; Dose-Response Relationship, Drug; Flavonols; Humans; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2016
Validation of flavonoids as potential dipeptidyl peptidase III inhibitors: Experimental and computational approach.
    Chemical biology & drug design, 2017, Volume: 89, Issue:4

    Topics: Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Flavonoids; Humans; Hydrophobic and Hydrophilic Interactions; Molecular Dynamics Simulation; Principal Component Analysis; Protease Inhibitors; Quantitative Structure-Activity Relationship

2017
Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
    Journal of natural products, 2017, 04-28, Volume: 80, Issue:4

    Topics: 17-Hydroxysteroid Dehydrogenases; Biological Products; Enzyme Inhibitors; Etiocholanolone; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Testosterone

2017
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.
    Journal of natural products, 2020, 05-22, Volume: 83, Issue:5

    Topics: Drug Design; Enzyme Inhibitors; Flavonoids; Fructose; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Liver; Molecular Structure

2020
A role of flavonoids in cytochrome c-cardiolipin interactions.
    Bioorganic & medicinal chemistry, 2021, 03-01, Volume: 33

    Topics: Cardiolipins; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship

2021
Inhibition by flavonoids of RNA synthesis in permeable WI-38 cells and of transcription by RNA polymerase II.
    Biochemical pharmacology, 1984, Dec-01, Volume: 33, Issue:23

    Topics: Animals; Cell Line; Cell Membrane Permeability; DNA Replication; Flavones; Flavonoids; Flavonols; Humans; Kaempferols; Kinetics; Mice; Quercetin; RNA Polymerase II; Structure-Activity Relationship; Transcription, Genetic

1984
Flavonols from Heterotheca inuloides: tyrosinase inhibitory activity and structural criteria.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:7

    Topics: Arnica; Binding Sites; Catechol Oxidase; Chelating Agents; Copper; Enzyme Inhibitors; Flavanones; Flavones; Flavonoids; Flavonols; Fungal Proteins; Inhibitory Concentration 50; Kaempferols; Kinetics; Levodopa; Monophenol Monooxygenase; Oxidation-Reduction; Plant Extracts; Plants, Medicinal; Quercetin; Spectrophotometry; Structure-Activity Relationship

2000
Interactions of different phenolic acids and flavonoids with soy proteins.
    International journal of biological macromolecules, 2002, Jun-18, Volume: 30, Issue:3-4

    Topics: Anilino Naphthalenesulfonates; Apigenin; Calorimetry, Differential Scanning; Caseins; Chymotrypsin; Circular Dichroism; Flavones; Flavonoids; Fluorescence; Globulins; Hydroxybenzoates; Kaempferols; Pancreatin; Pepsin A; Quercetin; Soybean Proteins; Structure-Activity Relationship; Trypsin; Trypsin Inhibitor, Kunitz Soybean

2002
Inhibition of lipopolysaccharide-induced nitric oxide production by flavonoids in RAW264.7 macrophages involves heme oxygenase-1.
    Biochemical pharmacology, 2003, Nov-01, Volume: 66, Issue:9

    Topics: Animals; Cell Line; Drug Interactions; Enzyme Induction; Flavanones; Flavones; Flavonoids; Gene Expression; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemin; Kaempferols; Lipopolysaccharides; Macrophages; Membrane Proteins; Metalloporphyrins; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protoporphyrins; Quercetin

2003
Flavones inhibit proliferation and increase mediator content in human leukemic mast cells (HMC-1).
    European journal of haematology, 2003, Volume: 71, Issue:6

    Topics: beta-N-Acetylhexosaminidases; Cell Division; Cell Survival; Flavones; Flavonoids; Histamine; Humans; Kaempferols; Leukemia, Mast-Cell; Mast Cells; Microscopy, Electron; Quercetin; Secretory Vesicles; Serine Endopeptidases; Tryptases; Tumor Cells, Cultured

2003
Dietary flavonol and flavone intakes and their major food sources in Chinese adults.
    Nutrition and cancer, 2010, Volume: 62, Issue:8

    Topics: Adolescent; Adult; Aged; China; Databases, Factual; Diet; Female; Flavones; Flavonols; Fruit; Health Surveys; Humans; Kaempferols; Male; Middle Aged; Nutritive Value; Plant Tubers; Quercetin; Reproducibility of Results; Solanum tuberosum; Vegetables; Young Adult

2010
[Chemical Constituents from Fruit Dregs of Rhus chinensis( Ⅱ)].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2016, Volume: 39, Issue:4

    Topics: Chromatography; Flavones; Fruit; Gallic Acid; Glycosides; Kaempferols; Quercetin; Rhus

2016