flavone has been researched along with 7-hydroxyflavone in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (23.33) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 15 (50.00) | 24.3611 |
| 2020's | 1 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, CJ; Geahlen, RL | 1 |
| Constantinou, A; Mehta, R; Moon, R; Rao, K; Runyan, C; Vaughan, A | 1 |
| Ares, JJ; Ems, BL; Kakodkar, SV; Kelm, GR; Kershaw, WC; Murray, PD; O'Brien, LM; Outt, PE; Randall, JL; Weisshaar, PS | 1 |
| Jacobson, KA; Ji, XD; Melman, N | 1 |
| Jacobson, KA; Moro, S; Sanders, LH; van Rhee, AM | 1 |
| Ash, K; Grohmann, K; Manthey, CL; Manthey, JA; Montanari, A | 1 |
| Dekermendjian, K; Kahnberg, P; Liljefors, T; Nielsen, M; Sterner, O; Witt, MR | 1 |
| Komai, K; Morimoto, M; Nakano, A; Nakano, S; Ozaki, T; Tanimoto, K | 1 |
| Chi, YS; Dao, TT; Kim, HP; Kim, J; Kim, S; Park, H | 1 |
| Ernst, B; Lill, MA; Vedani, A; Winiger, F | 1 |
| Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D | 1 |
| Autino, JC; Bennardi, DO; Castro, EA; Duchowicz, PR; Romanelli, GP; Vitale, MG | 1 |
| Kirchmair, J; Laggner, C; Langer, T; Nashev, LG; Odermatt, A; Schuster, D; Wolber, G | 1 |
| Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H | 1 |
| Binnie, M; Estrada-Soto, S; Medina-Franco, JL; Navarrete-Vázquez, G; Ortiz-Andrade, R; Singh, N; Torres-Piedra, M; Villalobos-Molina, R; Webster, SP | 1 |
| Muftuoglu, Y; Mustata, G | 1 |
| Autino, JC; Bennardi, DO; Del Valle Ortiz, E; Duchowicz, PR; Gaddi, AL; Romanelli, GP; Ruiz, DM; Virla, EG | 1 |
| Chan, CB; France, S; He, K; Huang, J; Jang, SW; Jia, Y; Liu, X; Luo, HR; Phun, LH; Pradoldej, S; Xiao, G; Ye, K | 1 |
| Estrada-Soto, S; Figueroa, M; Hernández-Abreu, O; Ibarra-Barajas, M; Navarrete-Vázquez, G; Torres-Piedra, M | 1 |
| Kogami, Y; Matsuda, H; Nakamura, S; Sugiyama, T; Ueno, T; Yoshikawa, M | 1 |
| Cho, SJ; Choi, CH; Gadhe, CG; Kothandan, G; Madhavan, T | 1 |
| Greeff, J; Joubert, J; Malan, SF; van Dyk, S | 1 |
| Balboni, G; Congiu, C; Maietti, A; Maresca, A; Onnis, V; Scozzafava, A; Supuran, CT; Winum, JY | 1 |
| Fernandes, E; Freitas, M; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM | 1 |
| Cabrita, EJ; Fernandes, E; Freitas, M; Marques, MM; Porto, G; Ribeiro, D; Silva, AM; Tomé, SM | 1 |
| Govil, G; Joshi, A; Joshi, UJ; Sinha, R; Srivastava, S | 1 |
| Akram, M; Atanasov, AG; Ateba, SB; Bachmann, F; Davis, RA; Engeli, RT; Krenn, L; Leugger, S; Njamen, D; Odermatt, A; Schuster, D; Stuppner, H; Temml, V; Vuorinen, A; Waltenberger, B | 1 |
| Dutour, R; Poirier, D | 1 |
| Fernandes, E; Fernandes, PA; Freitas, M; Oliveira, A; Proença, C; Ramos, MJ; Ribeiro, D; Silva, AMS; Sousa, JLC | 1 |
| Almandoz, MC; Blanco, SE; Castro, EA; Sancho, MI | 1 |
2 review(s) available for flavone and 7-hydroxyflavone
| Article | Year |
|---|---|
Protein-tyrosine kinase inhibition: mechanism-based discovery of antitumor agents.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Protein-Tyrosine Kinases | 1992 |
Inhibitors of cytochrome P450 (CYP) 1B1.
Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship | 2017 |
28 other study(ies) available for flavone and 7-hydroxyflavone
| Article | Year |
|---|---|
Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships.
Topics: DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Electrophoresis, Agar Gel; Flavonoids; Hydroxylation; Plasmids; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1995 |
Synthesis and biological evaluation of substituted flavones as gastroprotective agents.
Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Flavonoids; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Oxidoreductases; Rats; Rats, Sprague-Dawley; Stomach Diseases; Structure-Activity Relationship | 1995 |
Interactions of flavonoids and other phytochemicals with adenosine receptors.
Topics: Animals; Cell Line; CHO Cells; Cricetinae; Flavonoids; Humans; Magnetic Resonance Spectroscopy; Plants; Protein Binding; Radioligand Assay; Rats; Receptors, Purinergic P1 | 1996 |
Flavonoid derivatives as adenosine receptor antagonists: a comparison of the hypothetical receptor binding site based on a comparative molecular field analysis model.
Topics: Binding Sites; Computer Simulation; Flavonoids; Kinetics; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Molecular Structure; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A3; Receptors, Purinergic P1; Regression Analysis; Reproducibility of Results; Static Electricity; Structure-Activity Relationship | 1998 |
Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes.
Topics: Citrus; Cyclic AMP; Flavonoids; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 1999 |
Structure-activity relationships and molecular modeling analysis of flavonoids binding to the benzodiazepine site of the rat brain GABA(A) receptor complex.
Topics: Animals; Binding Sites; Brain; Flavonoids; In Vitro Techniques; Male; Models, Molecular; Molecular Conformation; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-A; Reproducibility of Results; Structure-Activity Relationship | 1999 |
Insect antifeedant activity of flavones and chromones against Spodoptera litura.
Topics: Animals; Chromones; Eating; Flavonoids; Gnaphalium; Insecticides; Methylation; Spodoptera; Structure-Activity Relationship | 2003 |
Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalysis; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Flavonoids; Isoenzymes; Mice; Prostaglandin Antagonists; Prostaglandin-Endoperoxide Synthases; Prostaglandins | 2004 |
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals.
Topics: Benzhydryl Compounds; Binding Sites; Diethylstilbestrol; Endocrine System; Hydrocarbons, Chlorinated; Ligands; Models, Molecular; Molecular Conformation; Phenols; Phytoestrogens; Quantitative Structure-Activity Relationship; Receptors, Androgen; Testosterone; Thermodynamics; Xenobiotics | 2005 |
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship | 2006 |
QSAR modeling of the interaction of flavonoids with GABA(A) receptor.
Topics: Binding Sites; Flavonoids; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, GABA-A | 2008 |
Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries.
Topics: 17-Hydroxysteroid Dehydrogenases; Catalysis; Cell Line; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavonoids; Humans; Models, Chemical; Small Molecule Libraries | 2008 |
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship | 2009 |
A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Animals; Blood Glucose; Computational Biology; Databases, Factual; Diabetes Mellitus, Experimental; Humans; Hypoglycemic Agents; Lipids; Models, Molecular; Molecular Conformation; Niacinamide; Quercetin; Rats; Software | 2010 |
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19).
Topics: Antineoplastic Agents; Aromatase; Aromatase Inhibitors; Binding Sites; Breast Neoplasms; Computer Simulation; Drug Design; Female; Humans; Models, Chemical; Models, Molecular; Structure-Activity Relationship | 2010 |
Sustainable synthesis of flavonoid derivatives, QSAR study and insecticidal activity against the fall armyworm, Spodoptera frugiperda (Lep.: Noctuidae).
Topics: Animals; Catalysis; Flavonoids; Insecticides; Quantitative Structure-Activity Relationship; Spodoptera | 2010 |
A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect.
Topics: Animals; Antidepressive Agents; Apoptosis; Flavones; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship | 2010 |
Vasorelaxant effect of flavonoids through calmodulin inhibition: Ex vivo, in vitro, and in silico approaches.
Topics: Animals; Aorta; Calmodulin; Dose-Response Relationship, Drug; Flavonoids; In Vitro Techniques; Models, Molecular; Rats; Rats, Wistar; Vasodilator Agents | 2011 |
Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.
Topics: 3T3-L1 Cells; Adipogenesis; Animals; CCAAT-Enhancer-Binding Protein-alpha; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; Deoxyglucose; Fatty Acid-Binding Proteins; Flavonoids; Glucose Transporter Type 4; Mice; PPAR gamma; Structure-Activity Relationship | 2011 |
Docking and 3D-QSAR (quantitative structure activity relationship) studies of flavones, the potent inhibitors of p-glycoprotein targeting the nucleotide binding domain.
Topics: Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B; Binding Sites; Flavones; Humans; Models, Molecular; Molecular Sequence Data; Nucleotides; Quantitative Structure-Activity Relationship; Sequence Homology, Amino Acid | 2011 |
Antioxidant properties of 4-quinolones and structurally related flavones.
Topics: 4-Quinolones; Antioxidants; Flavones; Humans; Hydrogen Peroxide; Hydroxyl Radical; Neurodegenerative Diseases | 2012 |
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins.
Topics: Benzopyrans; Carbonic Anhydrase Inhibitors; Coumarins; Flavones; Humans; Hydroxylation; Protein Isoforms; Structure-Activity Relationship | 2012 |
Modulation of human neutrophils' oxidative burst by flavonoids.
Topics: Flavonoids; Humans; Luminescent Measurements; Molecular Structure; Neutrophils; Oxidation-Reduction | 2013 |
Inhibition of LOX by flavonoids: a structure-activity relationship study.
Topics: Dose-Response Relationship, Drug; Flavonoids; Glycine max; Humans; Leukotriene B4; Lipoxygenase; Molecular Structure; Neutrophils; Structure-Activity Relationship | 2014 |
Localization and interaction of hydroxyflavones with lipid bilayer model membranes: a study using DSC and multinuclear NMR.
Topics: Biphenyl Compounds; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Flavones; Free Radical Scavengers; Humans; Hydroxides; Lipid Bilayers; Magnetic Resonance Spectroscopy; Picrates; Structure-Activity Relationship | 2014 |
Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
Topics: 17-Hydroxysteroid Dehydrogenases; Biological Products; Enzyme Inhibitors; Etiocholanolone; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Testosterone | 2017 |
Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase.
Topics: Drug Design; Enzyme Inhibitors; Flavonoids; Fructose; Fructose-Bisphosphatase; Humans; Hypoglycemic Agents; Liver; Molecular Structure | 2020 |
Spectroscopic study of solvent effects on the electronic absorption spectra of flavone and 7-hydroxyflavone in neat and binary solvent mixtures.
Topics: Absorption, Radiation; Acetonitriles; Cyclohexanes; Ethanol; Flavones; Flavonoids; Solvents; Spectrophotometry, Ultraviolet | 2011 |