Page last updated: 2024-08-23

flavone acetic acid and xanthenes

flavone acetic acid has been researched along with xanthenes in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's25 (86.21)18.2507
2000's3 (10.34)29.6817
2010's0 (0.00)24.3611
2020's1 (3.45)2.80

Authors

AuthorsStudies
Baguley, BC; Ching, LM; Gavin, JB; Thomsen, LL1
Baguley, BC; Thomsen, LL; Wilson, WR1
Back, TT; Baguley, BC; Eader, L; Futami, H; Gruys, E; Wiltrout, RH; Young, HA1
Baguley, BC; Ching, LM; Gavin, JB; Joseph, WR; Thomsen, LL1
Baguley, BC; Ching, LM; Joseph, WR2
Baguley, BC; Denny, WA; Kestell, P; McKeage, MJ1
Baguley, BC; Ching, LM; Joseph, WR; Kestell, P; McKeage, MJ; Zwi, LJ1
Baguley, BC; Ching, LM; Gavin, JB; Thomsen, LL; Zhuang, L1
Baguley, BC; Ching, LM; Thomsen, LL1
Baguley, BC; Gavin, JB; Wilson, WR; Zwi, LJ3
Baguley, BC; Denny, WA; Kestell, P; Rewcastle, GW1
Atwell, GJ; Baguley, BC; Denny, WA; Rewcastle, GW1
Ellis, AG; Kestell, P; Rewcastle, GW; Webster, LK1
Candeias, LP; Denny, WA; Everett, SA; Wardman, P1
Baguley, BC; Cliffe, S; Hill, RP; Rutland, M; Taylor, ML; Wilson, WR1
Baguley, BC; Cole, G; Li, Z; Thomsen, LL1
Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E1
Arnold, S; Chaplin, DJ; Watts, ME1
Begent, RH; Boden, JA; Boden, R; Boxer, GM; Flynn, AA; Keep, PA; Pedley, RB1
Baguley, BC; Kestell, P; Zhuang, L1
Phillips, RM1
Ching, LM; Eberly, K; Young, HA; Yu, CR1
Ching, LM; Kanwar, JR; Kanwar, RK; Krissansen, GW; Pandey, S1
Baguley, BC1
Horsman, MR; Murata, R1
Belluti, F; Bisi, A; Gobbi, S; Rampa, A1

Reviews

2 review(s) available for flavone acetic acid and xanthenes

ArticleYear
Small-molecule cytokine inducers causing tumor necrosis.
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Antineoplastic Agents; Capillary Permeability; Cytokines; Endothelium, Vascular; Flavonoids; Humans; Interferon-alpha; Mice; Microcirculation; Necrosis; Neoplasms; NF-kappa B; Nitric Oxide; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

2001
Flavonoid-Inspired Vascular Disrupting Agents: Exploring Flavone-8-Acetic Acid and Derivatives in the New Century.
    Molecules (Basel, Switzerland), 2021, Jul-12, Volume: 26, Issue:14

    Topics: Animals; Antineoplastic Agents; Clinical Trials, Phase III as Topic; Flavonoids; Humans; Neoplasms; Xanthenes; Xanthones

2021

Other Studies

27 other study(ies) available for flavone acetic acid and xanthenes

ArticleYear
Modulation of superoxide production from murine macrophages by the antitumour agent flavone acetic acid and xanthenone acetic acid analogues.
    Biochemical pharmacology, 1992, Jan-22, Volume: 43, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Macrophages; Mice; Mice, Inbred C3H; Necrosis; Superoxides; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Xanthenes

1992
Nitric oxide: its production in host-cell-infiltrated EMT6 spheroids and its role in tumour cell killing by flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Flavonoids; Mammary Neoplasms, Experimental; Nitric Oxide; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xanthenes; Xanthones

1992
Cytokine induction and therapeutic synergy with interleukin-2 against murine renal and colon cancers by xanthenone-4-acetic acid derivatives.
    Journal of immunotherapy : official journal of the Society for Biological Therapy, 1992, Volume: 12, Issue:4

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Combined Modality Therapy; Cytokines; DNA; DNA Probes; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Gene Expression Regulation, Neoplastic; Interferon-alpha; Interferon-gamma; Interleukin-2; Kidney Neoplasms; Leukocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Recombinant Proteins; Structure-Activity Relationship; Tumor Necrosis Factor-alpha; Xanthenes

1992
Nitric oxide production in endotoxin-resistant C3H/HeJ mice stimulated with flavone-8-acetic acid and xanthenone-4-acetic acid analogues.
    Biochemical pharmacology, 1992, Jun-09, Volume: 43, Issue:11

    Topics: Animals; Cells, Cultured; Drug Resistance; Endotoxins; Flavonoids; Macrophages; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitrates; Nitric Oxide; Time Factors; Tumor Necrosis Factor-alpha; Xanthenes

1992
Stimulation of macrophage tumouricidal activity by 5,6-dimethyl-xanthenone-4-acetic acid, a potent analogue of the antitumour agent flavone-8-acetic acid.
    Biochemical pharmacology, 1992, Jul-07, Volume: 44, Issue:1

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Dose-Response Relationship, Drug; Flavonoids; Macrophage Activation; Macrophages; Mice; Mice, Inbred C3H; Thioglycolates; Tumor Cells, Cultured; Xanthenes; Xanthones

1992
Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice.
    British journal of cancer, 1992, Volume: 66, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred Strains; Mice, Nude; Necrosis; T-Lymphocytes; Thymectomy; Xanthenes; Xanthones

1992
Plasma pharmacokinetics of the antitumour agents 5,6-dimethylxanthenone-4-acetic acid, xanthenone-4-acetic acid and flavone-8-acetic acid in mice.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:6

    Topics: Animals; Antineoplastic Agents; Blood Proteins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Flavonoids; Male; Mice; Mice, Inbred Strains; Protein Binding; Xanthenes; Xanthones

1991
Haematological effects in mice of the antitumour agents xanthenone-4-acetic acid, 5,6-dimethyl-xanthenone-4-acetic acid [correction of 5,6-methyl-] and flavone acetic acid.
    Cancer chemotherapy and pharmacology, 1991, Volume: 28, Issue:6

    Topics: Animals; Antineoplastic Agents; Blood; Blood Cells; Bone Marrow; Bone Marrow Cells; Colony-Forming Units Assay; Flavonoids; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Xanthenes; Xanthones

1991
Tumor-dependent increased plasma nitrate concentrations as an indication of the antitumor effect of flavone-8-acetic acid and analogues in mice.
    Cancer research, 1991, Jan-01, Volume: 51, Issue:1

    Topics: Adenocarcinoma; Animals; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Methylation; Mice; Mice, Inbred Strains; Nitrates; Nitrites; Xanthenes; Xanthones

1991
Evidence for the production of nitric oxide by activated macrophages treated with the antitumor agents flavone-8-acetic acid and xanthenone-4-acetic acid.
    Cancer research, 1990, Nov-01, Volume: 50, Issue:21

    Topics: Animals; Antineoplastic Agents; Arginine; Cell Survival; Colonic Neoplasms; Dexamethasone; Flavonoids; Macrophages; Mice; Neoplasm Transplantation; Nitrates; Nitric Acid; Nitric Oxide; omega-N-Methylarginine; Xanthenes

1990
Necrosis in non-tumour tissues caused by flavone acetic acid and 5,6-dimethyl xanthenone acetic acid.
    British journal of cancer, 1990, Volume: 62, Issue:6

    Topics: Animals; Antineoplastic Agents; Endometrium; Female; Flavonoids; Lymphoid Tissue; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Thrombosis; Xanthenes; Xanthones

1990
Light-induced breakdown of flavone acetic acid and xanthenone analogues in solution.
    Journal of the National Cancer Institute, 1990, Mar-21, Volume: 82, Issue:6

    Topics: Antineoplastic Agents; Decarboxylation; Flavonoids; Light; Photochemistry; Solutions; Xanthenes

1990
Potential antitumor agents. 60. Relationships between structure and in vivo colon 38 activity for 5-substituted 9-oxoxanthene-4-acetic acids.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:5

    Topics: Acetates; Adenocarcinoma; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Colonic Neoplasms; Flavonoids; Mice; Structure-Activity Relationship; Xanthenes

1990
Metabolism and elimination of 5,6-dimethylxanthenone-4-acetic acid in the isolated perfused rat liver.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:3

    Topics: Animals; Antineoplastic Agents; Bile; Flavonoids; Glucuronates; Glucuronic Acid; In Vitro Techniques; Liver; Male; Perfusion; Protein Binding; Rats; Rats, Sprague-Dawley; Xanthenes; Xanthones

1995
Correlation between immune and vascular activities of xanthenone acetic acid antitumor agents.
    Oncology research, 1994, Volume: 6, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Colonic Neoplasms; Female; Flavonoids; Immunity, Cellular; Male; Mice; Mice, Inbred Strains; Necrosis; Structure-Activity Relationship; Tumor Cells, Cultured; Xanthenes

1994
The morphological effects of the anti-tumor agents flavone acetic acid and 5,6-dimethyl xanthenone acetic acid on the colon 38 mouse tumor.
    Pathology, 1994, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Apoptosis; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron; Necrosis; Phosphocreatine; Xanthenes; Xanthones

1994
Decarboxylation of the antitumour drugs flavone-8-acetic acid and xanthenone-4-acetic acid by nitrogen dioxide.
    Anti-cancer drug design, 1994, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Decarboxylation; Flavonoids; Nitrogen Dioxide; Xanthenes

1994
Combining bioreductive drugs (SR 4233 or SN 23862) with the vasoactive agents flavone acetic acid or 5,6-dimethylxanthenone acetic acid.
    International journal of radiation oncology, biology, physics, 1994, May-15, Volume: 29, Issue:2

    Topics: Aniline Mustard; Animals; Antineoplastic Agents; Drug Synergism; Female; Flavonoids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Regional Blood Flow; Tirapazamine; Triazines; Xanthenes; Xanthones

1994
Serotonin involvement in the antitumour and host effects of flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
    Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:1

    Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyproheptadine; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Nitrates; Nitric Oxide; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

1993
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Xanthenes; Xanthones

1993
Changes in coagulation and permeability properties of human endothelial cells in vitro induced by TNF-alpha or 5,6 MeXAA.
    The British journal of cancer. Supplement, 1996, Volume: 27

    Topics: Antineoplastic Agents; Blood Coagulation; Capillary Permeability; Cells, Cultured; Endothelium, Vascular; Flavonoids; Humans; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

1996
Ablation of colorectal xenografts with combined radioimmunotherapy and tumor blood flow-modifying agents.
    Cancer research, 1996, Jul-15, Volume: 56, Issue:14

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Carcinoembryonic Antigen; Colorectal Neoplasms; Combined Modality Therapy; Flavonoids; Humans; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Radioimmunotherapy; Regional Blood Flow; Serotonin; Tissue Distribution; Transplantation, Heterologous; Xanthenes; Xanthones

1996
Increased plasma serotonin following treatment with flavone-8-acetic acid, 5,6-dimethylxanthenone-4-acetic acid, vinblastine, and colchicine: relation to vascular effects.
    Oncology research, 1997, Volume: 9, Issue:2

    Topics: Animals; Antineoplastic Agents; Colchicine; Colonic Neoplasms; Dose-Response Relationship, Drug; Flavonoids; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Serotonin; Time Factors; Vinblastine; Xanthenes; Xanthones

1997
Inhibition of DT-diaphorase (NAD(P)H:quinone oxidoreductase, EC 1.6.99.2) by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) and flavone-8-acetic acid (FAA): implications for bioreductive drug development.
    Biochemical pharmacology, 1999, Jul-15, Volume: 58, Issue:2

    Topics: Antineoplastic Agents; Aziridines; Cell Survival; Cytochrome Reductases; Cytochrome-B(5) Reductase; Enzyme Inhibitors; Flavonoids; Humans; Indolequinones; Indoles; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Tirapazamine; Triazines; Tumor Cells, Cultured; Vitamin K; Xanthenes; Xanthones

1999
Induction of STAT and NFkappaB activation by the antitumor agents 5,6-dimethylxanthenone-4-acetic acid and flavone acetic acid in a murine macrophage cell line.
    Biochemical pharmacology, 1999, Oct-01, Volume: 58, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cycloheximide; DNA-Binding Proteins; Flavonoids; Interferon-beta; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Protein Synthesis Inhibitors; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Xanthenes; Xanthones

1999
Vascular attack by 5,6-dimethylxanthenone-4-acetic acid combined with B7.1 (CD80)-mediated immunotherapy overcomes immune resistance and leads to the eradication of large tumors and multiple tumor foci.
    Cancer research, 2001, Mar-01, Volume: 61, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; B7-1 Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Female; Flavonoids; Gene Dosage; Genetic Therapy; Genetic Vectors; Immunotherapy; Killer Cells, Natural; Lymphocyte Subsets; Lymphoma; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; T-Lymphocytes, Cytotoxic; Thymus Neoplasms; Xanthenes; Xanthones

2001
Combination of vascular targeting agents with thermal or radiation therapy.
    International journal of radiation oncology, biology, physics, 2002, Dec-01, Volume: 54, Issue:5

    Topics: Adjuvants, Immunologic; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Dose-Response Relationship, Radiation; Flavonoids; Hyperthermia, Induced; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms; Neovascularization, Pathologic; Stilbenes; Temperature; Time Factors; Tumor Cells, Cultured; X-Rays; Xanthenes; Xanthones

2002