flavin-adenine-dinucleotide and dihydrouracil

flavin-adenine-dinucleotide has been researched along with dihydrouracil* in 1 studies

Other Studies

1 other study(ies) available for flavin-adenine-dinucleotide and dihydrouracil

Article	Year
A mild phenotype of dihydropyrimidine dehydrogenase deficiency and developmental retardation associated with a missense mutation affecting cofactor binding. Clinical biochemistry, 2011, Volume: 44, Issue:8-9 Evaluation of a non-synonymous mutation associated with dihydropyrimidine dehydrogenase (DPD) deficiency.. DPD enzyme analysis, mutation analysis and molecular dynamics simulations based on the 3D-model of DPD.. The substitution Lys63Glu is likely to affect the FAD binding pocket within the DPD protein and contributes to a near-complete DPD deficiency in a patient with developmental retardation.. Like other DPD variants attenuating FAD binding, Lys63Glu should be included in screening for DPD deficiency. Topics: Amino Acid Sequence; Child; Creatinine; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Flavin-Adenine Dinucleotide; Genotype; Humans; Male; Molecular Sequence Data; Mutation, Missense; Protein Binding; Sequence Homology, Amino Acid; Thymine; Uracil	2011

Article

Year

A mild phenotype of dihydropyrimidine dehydrogenase deficiency and developmental retardation associated with a missense mutation affecting cofactor binding.

Clinical biochemistry, 2011, Volume: 44, Issue:8-9

Evaluation of a non-synonymous mutation associated with dihydropyrimidine dehydrogenase (DPD) deficiency.. DPD enzyme analysis, mutation analysis and molecular dynamics simulations based on the 3D-model of DPD.. The substitution Lys63Glu is likely to affect the FAD binding pocket within the DPD protein and contributes to a near-complete DPD deficiency in a patient with developmental retardation.. Like other DPD variants attenuating FAD binding, Lys63Glu should be included in screening for DPD deficiency.

Topics: Amino Acid Sequence; Child; Creatinine; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Flavin-Adenine Dinucleotide; Genotype; Humans; Male; Molecular Sequence Data; Mutation, Missense; Protein Binding; Sequence Homology, Amino Acid; Thymine; Uracil

2011