fk 888 has been researched along with substance p, sar(9)-met(o2)(11)- in 5 studies
| Studies (fk 888) | Trials (fk 888) | Recent Studies (post-2010) (fk 888) | Studies (substance p, sar(9)-met(o2)(11)-) | Trials (substance p, sar(9)-met(o2)(11)-) | Recent Studies (post-2010) (substance p, sar(9)-met(o2)(11)-) |
|---|---|---|---|---|---|
| 97 | 2 | 3 | 151 | 0 | 6 |
| Protein | Taxonomy | fk 888 (IC50) | substance p, sar(9)-met(o2)(11)- (IC50) |
|---|---|---|---|
| Substance-P receptor | Homo sapiens (human) | 0.0006 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, PJ; Hirayama, Y; Lei, YH; Rogers, DF | 1 |
| Amerini, S; Ledda, F; Maggi, CA; Parenti, A; Ziche, M | 1 |
| Amerini, S; Ledda, F; Maggi, CA; Parenti, A; Zawieja, D; Ziche, M | 1 |
| Evangelista, S; Giachetti, A; Manzini, S; Paoli, S | 1 |
| Cirillo, R; Conte, B; Lopez, G; Maggi, CA; Manzini, S; Parlani, M | 1 |
5 other study(ies) available for fk 888 and substance p, sar(9)-met(o2)(11)-
| Article | Year |
|---|---|
Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo.
Topics: Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Dipeptides; Electric Stimulation; Evans Blue; Exudates and Transudates; Guinea Pigs; Hypotension; Indoles; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory Mechanics; Smoking; Substance P; Vagus Nerve | 1993 |
The tachykinin NK1 receptor mediates the migration-promoting effect of substance P on human skin fibroblasts in culture.
Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Cell Adhesion; Cell Movement; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Fibroblasts; Humans; Indoles; Male; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Platelet-Derived Growth Factor; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Skin; Substance P | 1996 |
Effect of the non-peptide blocker (+/-) CP 96,345 on the cellular mechanism involved in the response to NK1 receptor stimulation in human skin fibroblasts.
Topics: Biphenyl Compounds; Bradykinin; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Dipeptides; Fibroblasts; Humans; Hydrolysis; Indoles; Neurokinin-1 Receptor Antagonists; Phosphatidylinositols; Physalaemin; Receptors, Neurokinin-1; Skin; Stimulation, Chemical; Substance P | 1996 |
Involvement of tachykinin NK1 receptors in plasma protein extravasation induced by tachykinins in the guinea pig upper airways.
Topics: Animals; Antigens; Blood Proteins; Capsaicin; Dextrans; Dipeptides; Extravasation of Diagnostic and Therapeutic Materials; Fluorescein-5-isothiocyanate; Glycopeptides; Guinea Pigs; Indoles; Male; Nasal Mucosa; Neurokinin A; Neurokinin-1 Receptor Antagonists; Olfactory Receptor Neurons; Peptide Fragments; Peptides, Cyclic; Protease Inhibitors; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Rhinitis; Substance P | 1997 |
Inflammatory and motor responses by tachykinins in the guinea-pig oesophageal sphincter.
Topics: Animals; Dipeptides; Diphenhydramine; Dose-Response Relationship, Drug; Esophagogastric Junction; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Indoles; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P | 1998 |