Page last updated: 2024-09-02

fk 888 and substance p, sar(9)-met(o2)(11)-

fk 888 has been researched along with substance p, sar(9)-met(o2)(11)- in 5 studies

Compound Research Comparison

Studies
(fk 888)
Trials
(fk 888)
Recent Studies (post-2010)
(fk 888)
Studies
(substance p, sar(9)-met(o2)(11)-)
Trials
(substance p, sar(9)-met(o2)(11)-)
Recent Studies (post-2010) (substance p, sar(9)-met(o2)(11)-)
972315106

Protein Interaction Comparison

ProteinTaxonomyfk 888 (IC50)substance p, sar(9)-met(o2)(11)- (IC50)
Substance-P receptorHomo sapiens (human)0.0006

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, PJ; Hirayama, Y; Lei, YH; Rogers, DF1
Amerini, S; Ledda, F; Maggi, CA; Parenti, A; Ziche, M1
Amerini, S; Ledda, F; Maggi, CA; Parenti, A; Zawieja, D; Ziche, M1
Evangelista, S; Giachetti, A; Manzini, S; Paoli, S1
Cirillo, R; Conte, B; Lopez, G; Maggi, CA; Manzini, S; Parlani, M1

Other Studies

5 other study(ies) available for fk 888 and substance p, sar(9)-met(o2)(11)-

ArticleYear
Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo.
    British journal of pharmacology, 1993, Volume: 108, Issue:3

    Topics: Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Dipeptides; Electric Stimulation; Evans Blue; Exudates and Transudates; Guinea Pigs; Hypotension; Indoles; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory Mechanics; Smoking; Substance P; Vagus Nerve

1993
The tachykinin NK1 receptor mediates the migration-promoting effect of substance P on human skin fibroblasts in culture.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:5

    Topics: Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Cell Adhesion; Cell Movement; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Fibroblasts; Humans; Indoles; Male; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Platelet-Derived Growth Factor; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Skin; Substance P

1996
Effect of the non-peptide blocker (+/-) CP 96,345 on the cellular mechanism involved in the response to NK1 receptor stimulation in human skin fibroblasts.
    Neuropeptides, 1996, Volume: 30, Issue:4

    Topics: Biphenyl Compounds; Bradykinin; Calcium; Cells, Cultured; Cyclic AMP; Cytosol; Dipeptides; Fibroblasts; Humans; Hydrolysis; Indoles; Neurokinin-1 Receptor Antagonists; Phosphatidylinositols; Physalaemin; Receptors, Neurokinin-1; Skin; Stimulation, Chemical; Substance P

1996
Involvement of tachykinin NK1 receptors in plasma protein extravasation induced by tachykinins in the guinea pig upper airways.
    Neuropeptides, 1997, Volume: 31, Issue:1

    Topics: Animals; Antigens; Blood Proteins; Capsaicin; Dextrans; Dipeptides; Extravasation of Diagnostic and Therapeutic Materials; Fluorescein-5-isothiocyanate; Glycopeptides; Guinea Pigs; Indoles; Male; Nasal Mucosa; Neurokinin A; Neurokinin-1 Receptor Antagonists; Olfactory Receptor Neurons; Peptide Fragments; Peptides, Cyclic; Protease Inhibitors; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Rhinitis; Substance P

1997
Inflammatory and motor responses by tachykinins in the guinea-pig oesophageal sphincter.
    Journal of autonomic pharmacology, 1998, Volume: 18, Issue:5

    Topics: Animals; Dipeptides; Diphenhydramine; Dose-Response Relationship, Drug; Esophagogastric Junction; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Indoles; Inflammation; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Substance P

1998