fk 888 has been researched along with piperidines in 22 studies
| Studies (fk 888) | Trials (fk 888) | Recent Studies (post-2010) (fk 888) | Studies (piperidines) | Trials (piperidines) | Recent Studies (post-2010) (piperidines) |
|---|---|---|---|---|---|
| 97 | 2 | 3 | 40,235 | 5,221 | 14,545 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (54.55) | 18.2507 |
| 2000's | 9 (40.91) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gether, U; Schwartz, TW; Zoffmann, S | 1 |
| Gerard, NP; Gether, U; Jensen, CJ; Schwartz, TW | 1 |
| Brelière, JC; Emonds-Alt, X; Fujii, T; Garret, C; Gether, U; Hagiwara, D; Johansen, TE; Pradier, L; Schwartz, TW | 1 |
| Calixto, JB; Campos, AH; Cechinel Filho, V; Dias, MA; Yunes, RA | 1 |
| Hirayama, Y; Hiroi, J; Imai, T; Miyayasu, K; Yasumitsu, R | 1 |
| Fujita, H; Kurahashi, K; Nakagiri, R; Sasaki, R; Suganuma, H; Usui, H; Yoshikawa, M | 1 |
| Inoue, H; Koshihara, Y; Nagata, N | 1 |
| Calixto, JB; De Lima, TC; Rae, GA; Ribeiro, SJ; Santos, AR; Teixeira, RM | 1 |
| Ferrell, WR; Karimian, SM; Lockhart, JC | 1 |
| Calixto, JB; Medeiros, YS; Saleh, TS | 1 |
| Dong, F; Hasegawa, S; Iijima, H; Nomura, A; Uchida, Y; Xiang, A; Zhang, MJ | 1 |
| Ngan, MP; Rudd, JA; Wai, MK | 1 |
| Abe, S; Kaneko, S; Tanaka, H; Teramoto, S | 2 |
| Lam, FF; Yip, AL | 1 |
| Hayashi, I; Kamijo, Y; Majima, M; Ohwada, T; Soma, K | 1 |
| Bringas, A; Choppin, A; Dillon, MP; Groke, G; Stepan, G | 1 |
| Beirith, A; Calixto, JB; Santos, AR | 1 |
| Calixto, JB; El Sayah, M | 1 |
| Hamada, K; Hanioka, N; Imazumi, K; Maeda, Y; Manda, T; Matsuo, M; Mutoh, S; Yamamoto, T | 1 |
| De Lima, TC; Duarte, FS; Testolin, R | 1 |
| Abe, T; Fukuda, H; Yoshihara, S | 1 |
22 other study(ies) available for fk 888 and piperidines
| Article | Year |
|---|---|
Conserved HisVI-17 of the NK-1 receptor is involved in binding of non-peptide antagonists but not substance P.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Biphenyl Compounds; Cell Line; Cell Membrane; Conserved Sequence; Dipeptides; Humans; Indoles; Isoindoles; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurokinin-1 Receptor Antagonists; Piperidines; Protein Structure, Secondary; Quinuclidines; Receptors, Neurokinin-1; Recombinant Proteins; Sequence Homology, Amino Acid; Substance P; Transfection | 1993 |
The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors.
Topics: Amino Acid Sequence; Animals; Benzamides; Biphenyl Compounds; Cell Line; Dipeptides; Humans; Indoles; Molecular Sequence Data; Mutation; Neurokinin-1 Receptor Antagonists; Piperidines; Rats; Receptors, Neurokinin-1; Recombinant Proteins; Substance P | 1994 |
Evidence for a common molecular mode of action for chemically distinct nonpeptide antagonists at the neurokinin-1 (substance P) receptor.
Topics: Animals; Binding Sites; CHO Cells; Cricetinae; Dipeptides; Gene Transfer Techniques; Indoles; Inositol Phosphates; Isoindoles; Neurokinin-1 Receptor Antagonists; Piperidines; Quinuclidines; Rats; Receptors, Neurokinin-1; Receptors, Neurokinin-3 | 1994 |
Analysis of the mechanisms underlying the contractile response induced by the hydroalcoholic extract of Phyllanthus urinaria in the guinea-pig urinary bladder in-vitro.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Benzamides; Dipeptides; Ethanol; Female; Guinea Pigs; In Vitro Techniques; Indoles; Ion Channels; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurokinin A; Piperidines; Plant Extracts; Plants, Medicinal; Receptors, Tachykinin; Substance P; Urinary Bladder | 1995 |
Effects of specific tachykinin receptor antagonists on citric acid-induced cough and bronchoconstriction in unanesthetized guinea pigs.
Topics: Animals; Antacids; Benzamides; Bronchoconstriction; Citric Acid; Cough; Dipeptides; Guinea Pigs; Indoles; Male; Piperidines | 1996 |
Vasorelaxation by casomokinin L, a derivative of beta-casomorphin and casoxin D, is mediated by NK1 receptor.
Topics: Amino Acid Sequence; Animals; Antihypertensive Agents; Blood Pressure; Caseins; Dipeptides; Dogs; Endorphins; Endothelium, Vascular; Female; In Vitro Techniques; Indoles; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligopeptides; Piperidines; Rats; Rats, Inbred SHR; Receptors, Neurokinin-1; Sequence Homology, Amino Acid; Vasodilation | 1996 |
Effect of the tachykinin receptor antagonists, SR 140333, FK 888, and SR 142801, on capsaicin-induced mouse ear oedema.
Topics: Animals; Binding Sites; Capsaicin; Dipeptides; Disease Models, Animal; Ear Diseases; Edema; Indoles; Injections, Intravenous; Lethal Dose 50; Male; Mice; Piperidines; Quinuclidines; Receptors, Tachykinin; Skin; Stereoisomerism; Structure-Activity Relationship; Substance P | 1996 |
Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzamides; Dipeptides; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Mice; Motor Activity; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Postural Balance; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P | 1996 |
Tachykinin regulation of basal synovial blood flow.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Benzamides; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Hindlimb; Indoles; Joints; Laser-Doppler Flowmetry; Male; Microscopy, Electron; Nerve Fibers; Peptides, Cyclic; Phenoxybenzamine; Piperidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Receptors, Tachykinin; Regional Blood Flow; Synovial Membrane; Tachykinins; Vasoconstriction | 1997 |
Pro-inflammatory effects induced by bradykinin in a murine model of pleurisy.
Topics: Animals; Benzamides; Bradykinin; Bradykinin Receptor Antagonists; Cell Movement; Dipeptides; Dose-Response Relationship, Drug; Female; Indoles; Inflammation; Leukocyte Count; Male; Mice; Neutrophils; Oligopeptides; Piperidines; Pleura; Pleurisy; Receptor, Bradykinin B2; Time Factors | 1997 |
Effects of airway inflammation on cough response in the guinea pig.
Topics: Animals; Antitussive Agents; Benzamides; Bronchoalveolar Lavage Fluid; Capsaicin; Codeine; Cough; Dipeptides; Female; Guinea Pigs; Indoles; Inflammation; Peptides, Cyclic; Piperidines; Quinuclidines; Receptors, Neurokinin-2; Receptors, Tachykinin; Respiratory Hypersensitivity; Respiratory Tract Diseases | 1998 |
Inhibition of emesis by tachykinin NK1 receptor antagonists in Suncus murinus (house musk shrew).
Topics: Animals; Antiemetics; Copper Sulfate; Dipeptides; Dose-Response Relationship, Drug; Emetics; Female; Ganglionic Stimulants; Indoles; Infusions, Parenteral; Isoindoles; Male; Motion Sickness; Neurokinin-1 Receptor Antagonists; Nicotine; Physalaemin; Piperidines; Shrews; Stereoisomerism; Vomiting | 1999 |
Neurokinin-1 receptor antagonist inhibits short-term sulfuric-acid-induced airway hyperresponsiveness in sensitized guinea pigs.
Topics: Aerosols; Airway Resistance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Dipeptides; Guinea Pigs; Indoles; Male; Methacholine Chloride; Nebulizers and Vaporizers; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Receptors, Neurokinin-2; Sulfuric Acids | 2000 |
Unique gradual and sustained vasodilator response to substance P in the rabbit knee joint.
Topics: Administration, Topical; Animals; Benzamides; Cyclooxygenase Inhibitors; Dipeptides; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Flurbiprofen; Hindlimb; Indoles; Injections, Intra-Articular; Joints; Neurokinin-1 Receptor Antagonists; Piperidines; Rabbits; Receptors, Neurokinin-2; Regional Blood Flow; Substance P; Vasodilation | 2000 |
Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction.
Topics: Animals; Benzamides; Bradykinin; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Glycopeptides; Guinea Pigs; Indoles; Lung; Male; Metalloendopeptidases; Neurokinin A; Piperidines; Substance P | 2001 |
Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Dipeptides; Female; Indoles; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Spiro Compounds; Transfection; Urinary Bladder | 2002 |
Neurokinin-1 and neurokinin-2 antagonism inhibits long-term acid fog-induced airway hyperresponsiveness.
Topics: Airway Resistance; Animals; Benzamides; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoalveolar Lavage Fluid; Dipeptides; Eosinophilia; Guinea Pigs; Indoles; Leukocyte Count; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Sulfuric Acids; Weather | 2003 |
The role of neuropeptides and capsaicin-sensitive fibres in glutamate-induced nociception and paw oedema in mice.
Topics: Animals; Benzamides; Bradykinin Receptor Antagonists; Calcitonin Gene-Related Peptide; Capsaicin; Dipeptides; Edema; Foot; Glutamic Acid; Indoles; Male; Mice; Nerve Fibers; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain; Piperidines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Receptors, Neurokinin-2 | 2003 |
New evidence on the mechanisms underlying bradykinin-mediated contraction of the pig iris sphincter in vitro.
Topics: Animals; Benzamides; Bradykinin; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Calcium; Calcium Channels; Capsaicin; Carbazoles; Conotoxins; Dipeptides; Dose-Response Relationship, Drug; Egtazic Acid; In Vitro Techniques; Indoles; Iris; Maleimides; Muscle Contraction; Nicardipine; omega-Agatoxin IVA; Peptide Fragments; Piperidines; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Receptors, Calcitonin Gene-Related Peptide; Receptors, Drug; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Swine; Tachykinins | 2003 |
Contribution of tachykinin receptor subtypes to micturition reflex in guinea pigs.
Topics: Animals; Brain; Catheterization; CHO Cells; Cricetinae; Dipeptides; Dose-Response Relationship, Drug; Guinea Pigs; Humans; Indoles; Injections, Intravenous; Iodine Radioisotopes; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; Piperidines; Radioligand Assay; Receptors, Neurokinin-1; Spinal Cord; Substance P; Succinimides; Tetrazoles; Tissue Extracts; Transfection; Urinary Bladder; Urination | 2003 |
Further evidence on the anxiogenic-like effect of substance P evaluated in the elevated plus-maze in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Benzamides; Dipeptides; Dose-Response Relationship, Drug; Drug Interactions; Glycopeptides; Indoles; Injections, Intraventricular; Male; Maze Learning; Microinjections; Motor Activity; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Protease Inhibitors; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Neurokinin-2; Substance P; Thiorphan; Time Factors | 2004 |
The cannabinoid receptor agonist WIN 55,212-2 inhibits antigen-induced plasma extravasation in guinea pig airways.
Topics: Animals; Antigens; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Capillary Permeability; Dipeptides; Evans Blue; Extravasation of Diagnostic and Therapeutic Materials; Guinea Pigs; Immunization; Indoles; Inflammation; Male; Morpholines; Naphthalenes; Neurokinin-1 Receptor Antagonists; Ovalbumin; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Respiratory Hypersensitivity; Rimonabant; Trachea | 2010 |