fk 888 has been researched along with neurokinin a in 16 studies
| Studies (fk 888) | Trials (fk 888) | Recent Studies (post-2010) (fk 888) | Studies (neurokinin a) | Trials (neurokinin a) | Recent Studies (post-2010) (neurokinin a) |
|---|---|---|---|---|---|
| 97 | 2 | 3 | 1,765 | 34 | 91 |
| Protein | Taxonomy | fk 888 (IC50) | neurokinin a (IC50) |
|---|---|---|---|
| Substance-K receptor | Homo sapiens (human) | 0.0017 | |
| Neuromedin-K receptor | Homo sapiens (human) | 0.045 | |
| Substance-K receptor | Mesocricetus auratus (golden hamster) | 0.001 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (75.00) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kupryszewski, G; Maggi, CA; Patacchini, R; Quartara, L; Rolka, K; Zboinska, J | 1 |
| Giuliani, S; Holzer, P; Maggi, CA | 1 |
| Giuliani, S; Maggi, CA; Zagorodnyuk, V | 1 |
| Barnes, PJ; Hirayama, Y; Lei, YH; Rogers, DF | 1 |
| Fujii, T; Hagiwara, D; Ikari, N; Maeda, Y; Matsuo, M; Miyake, H; Murai, M | 1 |
| Fujii, T; Hagiwara, D; Maeda, Y; Matsuo, M; Miyake, H; Murai, M; Yamaoka, M | 1 |
| Calixto, JB; Campos, AH; Cechinel Filho, V; Dias, MA; Yunes, RA | 1 |
| Fujimura, M; Matsuda, T; Matsushima, K; Mizuguchi, M; Nomura, M; Tsujiura, M | 1 |
| Calixto, JB; De Lima, TC; Rae, GA; Ribeiro, SJ; Santos, AR; Teixeira, RM | 1 |
| Fujimura, M; Ishiura, Y; Matsuda, T; Myou, S; Tsujiura, M | 1 |
| Barnhart, DC; Kimball, BC; Mulholland, MW; Sarosi, GA; Zhang, W | 1 |
| Evangelista, S; Giachetti, A; Manzini, S; Paoli, S | 1 |
| Behar, J; Biancani, P; Cao, W; Kirber, MT; Pricolo, VE; Zhang, L | 1 |
| Hayashi, I; Kamijo, Y; Majima, M; Ohwada, T; Soma, K | 1 |
| Bringas, A; Choppin, A; Dillon, MP; Groke, G; Stepan, G | 1 |
| Morimoto, K; Mukaiyama, O; Nosaka, E; Takahashi, S; Tsuchida, H; Yamashita, M | 1 |
16 other study(ies) available for fk 888 and neurokinin a
| Article | Year |
|---|---|
Effect of scyliorhinin I and synthetic scyliorhinin I derivatives at mammalian tachykinin NK1, NK2 and NK3 receptors.
Topics: Amino Acid Sequence; Animals; Cricetinae; Dipeptides; Guinea Pigs; In Vitro Techniques; Indoles; Male; Mesocricetus; Molecular Sequence Data; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides, Cyclic; Rabbits; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Tachykinins | 1993 |
Effect of omega-conotoxin on cholinergic and tachykininergic excitatory neurotransmission to the circular muscle of the guinea-pig colon.
Topics: Acetylcholine; Animals; Atropine; Calcium Channel Blockers; Colon; Dipeptides; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indoles; Male; Methacholine Chloride; Motor Neurons; Neurokinin A; Oligopeptides; omega-Conotoxin GVIA; Peptides; Substance P; Tachykinins | 1994 |
Specialization of tachykinin NK1 and NK2 receptors in producing fast and slow atropine-resistant neurotransmission to the circular muscle of the guinea-pig colon.
Topics: Action Potentials; Animals; Atropine; Autonomic Nervous System; Colon; Dipeptides; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neuromuscular Junction; Nifedipine; Oligopeptides; Physalaemin; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Substance P; Synaptic Transmission | 1994 |
Effects of two novel tachykinin antagonists, FK224 and FK888, on neurogenic airway plasma exudation, bronchoconstriction and systemic hypotension in guinea-pigs in vivo.
Topics: Animals; Blood Pressure; Bronchoconstriction; Capsaicin; Dipeptides; Electric Stimulation; Evans Blue; Exudates and Transudates; Guinea Pigs; Hypotension; Indoles; Male; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Platelet Activating Factor; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Respiratory Mechanics; Smoking; Substance P; Vagus Nerve | 1993 |
Effects of an NK1 receptor antagonist, FK888, on constriction and plasma extravasation induced in guinea pig airway by neurokinins and capsaicin.
Topics: Animals; Capillary Permeability; Capsaicin; Dipeptides; Guinea Pigs; In Vitro Techniques; Indoles; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P; Trachea | 1993 |
The pharmacological properties of FK888, a novel dipeptide NK1 antagonist.
Topics: Animals; Bronchoconstriction; Capsaicin; Cell Membrane; Dipeptides; Edema; Guinea Pigs; Histamine; Ileum; In Vitro Techniques; Indoles; Kinetics; Lung; Muscle Contraction; Muscle, Smooth; Neurokinin A; Receptors, Neurokinin-1; Substance P | 1993 |
Analysis of the mechanisms underlying the contractile response induced by the hydroalcoholic extract of Phyllanthus urinaria in the guinea-pig urinary bladder in-vitro.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Benzamides; Dipeptides; Ethanol; Female; Guinea Pigs; In Vitro Techniques; Indoles; Ion Channels; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neurokinin A; Piperidines; Plant Extracts; Plants, Medicinal; Receptors, Tachykinin; Substance P; Urinary Bladder | 1995 |
Sensory neuropeptides are not directly involved in bronchial hyperresponsiveness induced by interleukin-8 in guinea-pigs in vivo.
Topics: Animals; Bronchial Hyperreactivity; Bronchial Provocation Tests; Dipeptides; Guinea Pigs; Histamine; Indoles; Interleukin-8; Male; Neurokinin A; Peptides, Cyclic; Substance P | 1996 |
Effects of central administration of tachykinin receptor agonists and antagonists on plus-maze behavior in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzamides; Dipeptides; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Mice; Motor Activity; Neurokinin A; Neurokinin-1 Receptor Antagonists; Piperidines; Postural Balance; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Tachykinin; Substance P | 1996 |
Role of sensory neuropeptides in post-allergic propranolol-induced bronchoconstriction in guinea pigs in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Asthma; Bronchial Hyperreactivity; Bronchoconstriction; Dipeptides; Guinea Pigs; Indoles; Male; Neurokinin A; Peptides, Cyclic; Propranolol; Substance P | 1996 |
Tachykinin neuropeptide-evoked intracellular calcium transients in cultured guinea pig myenteric neurons.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Diltiazem; Dipeptides; Fluorometry; Guinea Pigs; Indoles; Lanthanum; Myenteric Plexus; Neurokinin A; Nickel; Nifedipine; Peptide Fragments; Peptides, Cyclic; Receptors, Tachykinin; Substance P; Tachykinins; Virulence Factors, Bordetella | 1998 |
Involvement of tachykinin NK1 receptors in plasma protein extravasation induced by tachykinins in the guinea pig upper airways.
Topics: Animals; Antigens; Blood Proteins; Capsaicin; Dextrans; Dipeptides; Extravasation of Diagnostic and Therapeutic Materials; Fluorescein-5-isothiocyanate; Glycopeptides; Guinea Pigs; Indoles; Male; Nasal Mucosa; Neurokinin A; Neurokinin-1 Receptor Antagonists; Olfactory Receptor Neurons; Peptide Fragments; Peptides, Cyclic; Protease Inhibitors; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Rhinitis; Substance P | 1997 |
Gq-linked NK(2) receptors mediate neurally induced contraction of human sigmoid circular smooth muscle.
Topics: Aged; Aged, 80 and over; Calcium; Colon; Dipeptides; Electric Stimulation; Female; Gastrointestinal Motility; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Proteins; Humans; In Vitro Techniques; Indoles; Intracellular Membranes; Male; Middle Aged; Muscle, Smooth; Nervous System Physiological Phenomena; Neurokinin A; Receptors, Neurokinin-2 | 2000 |
Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction.
Topics: Animals; Benzamides; Bradykinin; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Capsaicin; Dipeptides; Dose-Response Relationship, Drug; Drug Antagonism; Drug Interactions; Glycopeptides; Guinea Pigs; Indoles; Lung; Male; Metalloendopeptidases; Neurokinin A; Piperidines; Substance P | 2001 |
Effect of YM-44781, YM-44778 and YM-49598, novel tachykinin antagonists, in a drug-induced bladder contraction model.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Dipeptides; Female; Indoles; Muscle Contraction; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Spiro Compounds; Transfection; Urinary Bladder | 2002 |
Novel triple neurokinin receptor antagonist CS-003 strongly inhibits neurokinin related responses.
Topics: Animals; Bronchi; Capillary Permeability; Capsaicin; Chlorocebus aethiops; Citric Acid; COS Cells; Cough; Cyclic S-Oxides; Dipeptides; Dose-Response Relationship, Drug; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Inositol Phosphates; Male; Molecular Sequence Data; Morpholines; Neurokinin A; Neurokinin B; Neurokinin-1 Receptor Antagonists; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Substance P; Trachea | 2008 |