Compounds > fk 224
Page last updated: 2024-09-03

fk 224 and indomethacin

fk 224 has been researched along with indomethacin in 2 studies

Compound Research Comparison

Studies
(fk 224)		Trials
(fk 224)		Recent Studies (post-2010)
(fk 224)		Studies
(indomethacin)		Trials
(indomethacin)		Recent Studies (post-2010) (indomethacin)
443029,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyfk 224 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirose, T; Kano, S; Kuroiwa, C; Nishima, S; Nogami, H; Umeno, E1
Fujii, T; Matsuda, A; Miyake, H; Morimoto, H; Ohori, M; Yamashita, M1

Other Studies

2 other study(ies) available for fk 224 and indomethacin

ArticleYear
Role of tachykinins in bronchoconstriction induced by intravenous administration of bradykinin in guinea-pigs.
    The European respiratory journal, 1996, Volume: 9, Issue:4

    Topics: Animals; Bradykinin; Bronchoconstriction; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; Indomethacin; Male; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Plethysmography, Whole Body; Receptors, Neurokinin-2; Tachykinins

1996
Characterization of dextran sulfate-induced guinea pig tracheal plasma extravasation.
    Japanese journal of pharmacology, 1996, Volume: 72, Issue:3

    Topics: Analysis of Variance; Animals; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Cyclooxygenase Inhibitors; Dextrans; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Peptides, Cyclic; Trachea

1996