fk 224 has been researched along with cp 96345 in 3 studies
| Studies (fk 224) | Trials (fk 224) | Recent Studies (post-2010) (fk 224) | Studies (cp 96345) | Trials (cp 96345) | Recent Studies (post-2010) (cp 96345) |
|---|---|---|---|---|---|
| 44 | 3 | 0 | 403 | 1 | 16 |
| Protein | Taxonomy | fk 224 (IC50) | cp 96345 (IC50) |
|---|---|---|---|
| Substance-P receptor | Homo sapiens (human) | 0.0028 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujii, T; Kiyotoh, S; Maeda, Y; Morimoto, H; Murai, M; Nishikawa, M; Yamaoka, M | 1 |
| Gomi, Y; Mizuno, K; Suzuki, N | 1 |
| Mizuguchi, T; Shimoyama, N; Yamamoto, T | 1 |
3 other study(ies) available for fk 224 and cp 96345
| Article | Year |
|---|---|
FK 224, a novel cyclopeptide substance P antagonist with NK1 and NK2 receptor selectivity.
Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Cerebral Cortex; Guinea Pigs; Lung; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptides, Cyclic; Rats; Rats, Inbred Strains; Receptors, Neurokinin-2; Receptors, Neurotransmitter; Substance P | 1992 |
Tachykinin-induced contractions in the circular muscle of guinea pig ileum.
Topics: Animals; Atropine; Biphenyl Compounds; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Hypnotics and Sedatives; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin A; Neurokinin B; Peptides, Cyclic; Rats; Structure-Activity Relationship; Substance P; Tachykinins; Tetrodotoxin | 1994 |
Effects of FK224, a novel cyclopeptide NK1 and NK2 antagonist, and CP-96,345, a nonpeptide NK1 antagonist, on development and maintenance of thermal hyperesthesia evoked by carrageenan injection in the rat paw.
Topics: Animals; Biphenyl Compounds; Carrageenan; Extremities; Hot Temperature; Hyperesthesia; Male; Neurokinin A; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Substance P | 1993 |