Page last updated: 2024-09-03

fk 224 and bradykinin

fk 224 has been researched along with bradykinin in 5 studies

Compound Research Comparison

Studies (fk 224)	Trials (fk 224)	Recent Studies (post-2010) (fk 224)	Studies (bradykinin)	Trials (bradykinin)	Recent Studies (post-2010) (bradykinin)
44	3	0	14,195	355	1,520

Protein Interaction Comparison

Protein	Taxonomy	fk 224 (IC50)	bradykinin (IC50)
B2 bradykinin receptor	Homo sapiens (human)		0.0018

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ichinose, M; Inoue, H; Nakajima, N; Takahashi, T; Takishima, T; Yamauchi, H	1
Hirose, T; Kano, S; Kuroiwa, C; Nishima, S; Nogami, H; Umeno, E	1
Jörres, RA; Magnussen, H; Rabe, KF; Schmidt, D	1
Arakawa, M; Goto, F; Katori, M; Majima, M; Nagai, K	1
Fujii, T; Matsuda, A; Miyake, H; Morimoto, H; Ohori, M; Yamashita, M	1

Trials

2 trial(s) available for fk 224 and bradykinin

Article	Year
Protection against bradykinin-induced bronchoconstriction in asthmatic patients by neurokinin receptor antagonist. Lancet (London, England), 1992, Nov-21, Volume: 340, Issue:8830 Topics: Administration, Inhalation; Adult; Asthma; Bradykinin; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Humans; Male; Middle Aged; Peptides, Cyclic; Placebos; Tachykinins	1992
Reproducibility of airway response to inhaled bradykinin and effect of the neurokinin receptor antagonist FK-224 in asthmatic subjects. European journal of clinical pharmacology, 1996, Volume: 50, Issue:4 Topics: Administration, Inhalation; Adult; Analysis of Variance; Asthma; Bradykinin; Bronchoconstriction; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Male; Peptides, Cyclic	1996

Article

Year

Protection against bradykinin-induced bronchoconstriction in asthmatic patients by neurokinin receptor antagonist.

Lancet (London, England), 1992, Nov-21, Volume: 340, Issue:8830

Topics: Administration, Inhalation; Adult; Asthma; Bradykinin; Bronchial Provocation Tests; Bronchoconstriction; Double-Blind Method; Female; Humans; Male; Middle Aged; Peptides, Cyclic; Placebos; Tachykinins

1992

Reproducibility of airway response to inhaled bradykinin and effect of the neurokinin receptor antagonist FK-224 in asthmatic subjects.

European journal of clinical pharmacology, 1996, Volume: 50, Issue:4

Topics: Administration, Inhalation; Adult; Analysis of Variance; Asthma; Bradykinin; Bronchoconstriction; Dose-Response Relationship, Drug; Female; Forced Expiratory Volume; Humans; Male; Peptides, Cyclic

1996

Other Studies

3 other study(ies) available for fk 224 and bradykinin

Article	Year
Role of tachykinins in bronchoconstriction induced by intravenous administration of bradykinin in guinea-pigs. The European respiratory journal, 1996, Volume: 9, Issue:4 Topics: Animals; Bradykinin; Bronchoconstriction; Dose-Response Relationship, Drug; Drug Therapy, Combination; Guinea Pigs; Indomethacin; Male; Neurokinin-1 Receptor Antagonists; Peptides, Cyclic; Plethysmography, Whole Body; Receptors, Neurokinin-2; Tachykinins	1996
Role of tachykinins in enhancement of bradykinin-induced bronchoconstriction by captopril. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Benzamides; Bradykinin; Bronchoconstriction; Capsaicin; Captopril; Dose-Response Relationship, Drug; Drug Synergism; Guinea Pigs; Male; Neurokinin A; Peptides, Cyclic; Piperidines; Substance P	1996
Characterization of dextran sulfate-induced guinea pig tracheal plasma extravasation. Japanese journal of pharmacology, 1996, Volume: 72, Issue:3 Topics: Analysis of Variance; Animals; Bradykinin; Bradykinin Receptor Antagonists; Capillary Permeability; Cyclooxygenase Inhibitors; Dextrans; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Peptides, Cyclic; Trachea	1996