Page last updated: 2024-09-05

firocoxib and uric acid

firocoxib has been researched along with uric acid in 4 studies

*Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN. [MeSH]

*Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN. [MeSH]

Compound Research Comparison

Studies
(firocoxib)
Trials
(firocoxib)
Recent Studies (post-2010)
(firocoxib)
Studies
(uric acid)
Trials
(uric acid)
Recent Studies (post-2010) (uric acid)
102437127,9801,7179,982

Protein Interaction Comparison

ProteinTaxonomyfirocoxib (IC50)uric acid (IC50)
Solute carrier family 2, facilitated glucose transporter member 9Homo sapiens (human)300

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hanson, PD; Hazewinkel, HA; Pollmeier, M; Theyse, LF; van den Brom, WE1
Drag, M; Hanson, PD; Kunkle, BN; Romano, D1
Al-Nadaf, S; Budsberg, SC; Cathcart, CJ; Johnston, SA; Reynolds, LR1
Beugnet, F; de Salazar Alcalá, AG; Dehman, A; Gioda, L1

Trials

4 trial(s) available for firocoxib and uric acid

ArticleYear
Comparison of the effects of firocoxib, carprofen and vedaprofen in a sodium urate crystal induced synovitis model of arthritis in dogs.
    Research in veterinary science, 2008, Volume: 84, Issue:1

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Carbazoles; Cross-Over Studies; Dog Diseases; Dogs; Female; Lameness, Animal; Male; Naphthalenes; Propionates; Sulfones; Synovitis; Time Factors; Uric Acid

2008
Firocoxib efficacy preventing urate-induced synovitis, pain, and inflammation in dogs.
    Veterinary therapeutics : research in applied veterinary medicine, 2007,Spring, Volume: 8, Issue:1

    Topics: 4-Butyrolactone; Animals; Carbazoles; Cyclooxygenase 2 Inhibitors; Dog Diseases; Dogs; Female; Lameness, Animal; Male; Meloxicam; Severity of Illness Index; Sulfonamides; Sulfones; Synovitis; Thiazines; Thiazoles; Treatment Outcome; Uric Acid

2007
Efficacy of ABT-116, an antagonist of transient receptor potential vanilloid type 1, in providing analgesia for dogs with chemically induced synovitis.
    American journal of veterinary research, 2012, Volume: 73, Issue:1

    Topics: 4-Butyrolactone; Analgesia; Animals; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Indazoles; Injections, Intra-Articular; Lameness, Animal; Male; Phenylurea Compounds; Stifle; Sulfones; Synovitis; TRPV Cation Channels; Uric Acid

2012
Assessment of the efficacy of firocoxib (Previcox®) and grapiprant (Galliprant®) in an induced model of acute arthritis in dogs.
    BMC veterinary research, 2019, Aug-29, Volume: 15, Issue:1

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Dog Diseases; Dogs; Lameness, Animal; Random Allocation; Sulfones; Sulfonylurea Compounds; Uric Acid

2019