Page last updated: 2024-09-05

firocoxib and dinoprostone

firocoxib has been researched along with dinoprostone in 7 studies

Compound Research Comparison

Studies
(firocoxib)
Trials
(firocoxib)
Recent Studies (post-2010)
(firocoxib)
Studies
(dinoprostone)
Trials
(dinoprostone)
Recent Studies (post-2010) (dinoprostone)
102437129,1051,3466,357

Protein Interaction Comparison

ProteinTaxonomyfirocoxib (IC50)dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtypeHomo sapiens (human)0.0155
Prostaglandin E2 receptor EP4 subtypeHomo sapiens (human)0.0031
Prostaglandin E2 receptor EP4 subtypeRattus norvegicus (Norway rat)0.0021
Prostaglandin E2 receptor EP3 subtypeHomo sapiens (human)0.002
Prostaglandin E2 receptor EP2 subtypeHomo sapiens (human)0.0087
Prostacyclin receptorHomo sapiens (human)0.26
Prostaglandin E2 receptor EP2 subtypeRattus norvegicus (Norway rat)0.0052

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Budsberg, SC; Goodman, LA; Reynolds, LR; Torres, BT1
Barton, MH; Budsberg, S; Giguère, S; King, D; Norton, N; Paske, E1
Chandler, KJ; Sutton, DG1
Barlow, BM; Blikslager, AT; Curling, A; Davis, JL; Fogle, C; Holland, B; Schirmer, J1
Boos, A; Domosławska, A; Fingerhut, J; Gram, A; Hoffmann, B; Ihle, S; Janowski, T; Jurczak, A; Kowalewski, MP; Schuler, G; Siemieniuch, MJ; Zduńczyk, S1
Barton, MH; Clifton, S; Darden, JE; Vandenplas, M1
Beale, B; Jarudecha, T; Kashemsant, N; Kwananocha, I; Lascelles, BDX; Lekcharoensuk, C; Peirone, B; Vijarnsorn, M1

Trials

4 trial(s) available for firocoxib and dinoprostone

ArticleYear
Efficacy of cyclo-oxygenase inhibition by two commercially available firocoxib products in horses.
    Equine veterinary journal, 2014, Volume: 46, Issue:1

    Topics: 4-Butyrolactone; Administration, Oral; Animals; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Dinoprostone; Dosage Forms; Horses; Sulfones

2014
Pharmacokinetics and pharmacodynamics of three formulations of firocoxib in healthy horses.
    Journal of veterinary pharmacology and therapeutics, 2015, Volume: 38, Issue:3

    Topics: 4-Butyrolactone; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Dinoprostone; Horses; Injections, Intravenous; Ointments; Sulfones; Tablets; Thromboxane B2

2015
Formation of the early canine CL and the role of prostaglandin E2 (PGE2) in regulation of its function: an in vivo approach.
    Theriogenology, 2015, Apr-01, Volume: 83, Issue:6

    Topics: 4-Butyrolactone; Animals; Corpus Luteum; Dinoprost; Dinoprostone; Dogs; Female; Gene Expression Regulation; Intramolecular Oxidoreductases; Male; Prostaglandin-E Synthases; Receptors, Prostaglandin; Sulfones

2015
The effectiveness of marine based fatty acid compound (PCSO-524) and firocoxib in the treatment of canine osteoarthritis.
    BMC veterinary research, 2019, Oct-17, Volume: 15, Issue:1

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Dog Diseases; Dogs; Double-Blind Method; Drug Therapy, Combination; Fatty Acids, Unsaturated; Female; Gait; Male; Osteoarthritis; Pain; Pain Measurement; Prospective Studies; Sulfones

2019

Other Studies

3 other study(ies) available for firocoxib and dinoprostone

ArticleYear
Effects of firocoxib, meloxicam, and tepoxalin administration on eicosanoid production in target tissues of healthy cats.
    American journal of veterinary research, 2010, Volume: 71, Issue:9

    Topics: 4-Butyrolactone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cats; Cross-Over Studies; Cyclooxygenase Inhibitors; Dinoprostone; Duodenum; Eicosanoids; Gastric Mucosa; Intestinal Mucosa; Kinetics; Leukotriene B4; Male; Meloxicam; Orchiectomy; Pyrazoles; Reference Values; Sulfones; Thiazines; Thiazoles

2010
The dilemmas of medicine selection for equine veterinarians.
    Equine veterinary journal, 2014, Volume: 46, Issue:1

    Topics: 4-Butyrolactone; Animals; Cyclooxygenase 2 Inhibitors; Dinoprostone; Horses; Sulfones

2014
Effect of firocoxib on cyclooxygenase 2, microsomal prostaglandin E2 synthase 1, and cytosolic phospholipase A2 gene expression in equine mononuclear cells.
    American journal of veterinary research, 2015, Volume: 76, Issue:12

    Topics: 4-Butyrolactone; Animals; Centrifugation, Density Gradient; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytosol; Dinoprostone; Gene Expression Regulation; Horses; Intramolecular Oxidoreductases; Leukocytes, Mononuclear; Lipopolysaccharides; Membrane Proteins; Microsomes; Phospholipases A2; Polymerase Chain Reaction; Prostaglandin-E Synthases; Sulfones

2015