Page last updated: 2024-09-02

fingolimod hydrochloride and thermozymocidin

fingolimod hydrochloride has been researched along with thermozymocidin in 11 studies

Compound Research Comparison

Studies
(fingolimod hydrochloride)
Trials
(fingolimod hydrochloride)
Recent Studies (post-2010)
(fingolimod hydrochloride)
Studies
(thermozymocidin)
Trials
(thermozymocidin)
Recent Studies (post-2010) (thermozymocidin)
2,7711572,0622671148

Protein Interaction Comparison

ProteinTaxonomyfingolimod hydrochloride (IC50)thermozymocidin (IC50)
Serine palmitoyltransferase 2Homo sapiens (human)0.0001

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's4 (36.36)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Kawasaki, T; Kozutsumi, Y; Nakamura, S1
Napoli, KL1
Fujita, T; Hirose, R; Kohno, T; Kurio, W; Matsumoto, N; Shimizu, T; Uchida, S; Watabe, K; Yanada, K1
Takeya, H1
Harada, T; Kanekake, H; Nishikido, M1
Ciesek, S; Manns, MP; Pietschmann, T; Steinmann, E; Wedemeyer, H1
Oberlies, NH; Pearce, CJ; Strader, CR1
Yeung, BK1
Hogan, EL; Krotkiewski, H; Podbielska, M1
Adachi, K; Chiba, K1
Chiba, K1

Reviews

8 review(s) available for fingolimod hydrochloride and thermozymocidin

ArticleYear
["Sphingosine pathway": a novel apoptosis inducing pathway].
    Seikagaku. The Journal of Japanese Biochemical Society, 1996, Volume: 68, Issue:6

    Topics: Animals; Apoptosis; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Immunosuppressive Agents; Propylene Glycols; Signal Transduction; Sphingosine

1996
The FTY720 story.
    Therapeutic drug monitoring, 2000, Volume: 22, Issue:1

    Topics: Animals; Clinical Trials as Topic; Drug Combinations; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunity, Cellular; Immunosuppressive Agents; Propylene Glycols; Sphingosine

2000
[Molecular action mechanisms of the therapeutic agents for kidney diseases: Immunosuppressants].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2

    Topics: Antibodies, Monoclonal; Azathioprine; Basiliximab; Cyclophosphamide; Cyclosporine; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid; Propylene Glycols; Recombinant Fusion Proteins; Ribonucleosides; Sphingosine

2006
Fingolimod (FTY720): a recently approved multiple sclerosis drug based on a fungal secondary metabolite.
    Journal of natural products, 2011, Apr-25, Volume: 74, Issue:4

    Topics: Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Hypocreales; Immunosuppressive Agents; Multiple Sclerosis; Propylene Glycols; Sphingosine; Structure-Activity Relationship; United States; United States Food and Drug Administration

2011
Natural product drug discovery: the successful optimization of ISP-1 and halichondrin B.
    Current opinion in chemical biology, 2011, Volume: 15, Issue:4

    Topics: Biological Products; Drug Discovery; Ethers, Cyclic; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Furans; Ketones; Macrolides; Molecular Structure; Propylene Glycols; Sphingosine; Structure-Activity Relationship

2011
Signaling and regulatory functions of bioactive sphingolipids as therapeutic targets in multiple sclerosis.
    Neurochemical research, 2012, Volume: 37, Issue:6

    Topics: Apoptosis; Ceramides; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Humans; Lysophospholipids; Metabolic Networks and Pathways; Multiple Sclerosis; Myelin Sheath; Propylene Glycols; Receptors, G-Protein-Coupled; Serine C-Palmitoyltransferase; Signal Transduction; Sphingolipids; Sphingosine

2012
Discovery of fingolimod, the sphingosine 1-phosphate receptor modulator and its application for the therapy of multiple sclerosis.
    Future medicinal chemistry, 2012, Volume: 4, Issue:6

    Topics: Animals; Drug Discovery; Encephalomyelitis, Autoimmune, Experimental; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Kidney Transplantation; Lymphocytes; Multiple Sclerosis; Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine

2012
Discovery of fingolimod based on the chemical modification of a natural product from the fungus, Isaria sinclairii.
    The Journal of antibiotics, 2020, Volume: 73, Issue:10

    Topics: Animals; Drug Discovery; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Humans; Hypocreales; Lymphocytes; Multiple Sclerosis; Structure-Activity Relationship

2020

Other Studies

3 other study(ies) available for fingolimod hydrochloride and thermozymocidin

ArticleYear
Antibody against a novel, myriocin (ISP-I)-based immunosuppressant, FTY720.
    Bioorganic & medicinal chemistry letters, 2000, Feb-21, Volume: 10, Issue:4

    Topics: Animals; Antibodies; Antibody Formation; Antibody Specificity; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Immunosuppressive Agents; Propanolamines; Propylene Glycols; Rabbits; Sphingosine

2000
['Vegetable wasps and plant worms' and G-protein-coupled receptors].
    Journal of UOEH, 2004, Jun-01, Volume: 26, Issue:2

    Topics: Cordyceps; Depression, Chemical; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Immunosuppressive Agents; Inflammation Mediators; Ligands; Lymphocyte Count; Lymphocytes; Lysophospholipids; Phosphorylation; Propylene Glycols; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; Sphingosine

2004
The suppressive effect that myriocin has on hepatitis C virus RNA replication is independent of inhibition of serine palmitoyl transferase.
    The Journal of infectious diseases, 2008, Oct-01, Volume: 198, Issue:7

    Topics: Antiviral Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Hepacivirus; Propylene Glycols; RNA, Viral; Serine C-Palmitoyltransferase; Sphingosine; Virus Replication

2008