fingolimod hydrochloride has been researched along with tacrolimus in 26 studies
| Studies (fingolimod hydrochloride) | Trials (fingolimod hydrochloride) | Recent Studies (post-2010) (fingolimod hydrochloride) | Studies (tacrolimus) | Trials (tacrolimus) | Recent Studies (post-2010) (tacrolimus) |
|---|---|---|---|---|---|
| 2,771 | 157 | 2,062 | 17,757 | 2,319 | 6,661 |
| Protein | Taxonomy | fingolimod hydrochloride (IC50) | tacrolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 7.18 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.58 | |
| Cytochrome P450 3A5 | Homo sapiens (human) | 0.385 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0021 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.2547 | |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Homo sapiens (human) | 0.0148 | |
| Splicing factor 3B subunit 3 | Homo sapiens (human) | 0.0123 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 3.3 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 3.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 15 (57.69) | 29.6817 |
| 2010's | 6 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Afford, SC; Antoniou, EA; D'Silva, M; McMaster, P; Pirenne, J; Suzuki, S; Xu, M | 1 |
| Chiba, K; Hoshino, Y; Kataoka, H; Kawaguchi, T; Masubuchi, Y; Ohtsuki, M; Yanagawa, Y | 1 |
| Afford, SC; Antoniou, EA; D'Silva, M; McMaster, P; Pirenne, J; Xu, M | 1 |
| Antoniou, S; D'Silva, M; Gunson, B; McMaster, P; Pirenne, J; Xu, M | 1 |
| Amemiya, H; Enosawa, S; Funeshima, N; Li, XK; Suzuki, S; Tamura, A | 1 |
| Amemiya, H; Enosawa, S; Funeshima, N; Kitajima, M; Li, XK; Suzuki, S; Tamura, A | 1 |
| Fujita, M; Fukai, M; Furukawa, H; Hayashi, T; Ishikawa, H; Jin, MB; Kishida, A; Magata, S; Masuko, H; Nagashima, K; Ogata, K; Omura, T; Shimamura, T; Suzuki, T; Taniguchi, M; Todo, S; Yamashita, K | 1 |
| Isobe, M; Kitabayashi, H; Sekiguchi, M; Suzuki, J; Watanabe, N; Yazaki, Y | 1 |
| Chiba, K; Imayoshi, T; Matsuura, M; Okumoto, T | 1 |
| Kelly, DA; van Mourik, ID | 1 |
| Diaz-Romero, J; Vogt, G; Weckbecker, G | 1 |
| Dumont, FJ | 1 |
| Braun, WE | 1 |
| McDonald, RA; Nemeth, TL; Smith, JM | 1 |
| Fujita, M; Fukai, M; Furukawa, H; Horiuchi, H; Jin, MB; Magata, S; Nagashima, K; Nomura, M; Shimamura, T; Suzuki, T; Taniguchi, M; Todo, S; Yamashita, K; Yokota, R | 1 |
| Baczkowska, T; Durlik, M | 1 |
| Cai, JQ; Dong, WP; Tan, JM; Wang, JB; Wang, YF | 1 |
| Bueno, V; Burdmann, EA; Franco, M; Gallo, AP; Silva, LB | 1 |
| Bueno, V; Cury, PM; Gallo, AP; Lopes, CT; Palma, PV | 1 |
| Cao, X; Sun, Y; Zhang, A; Zhang, J; Zhang, N | 1 |
| Furuya, T; Ikeda, T; Inoue, M; Kawashima, H; Konuma, N; Koshinaga, T; Masuko, T; Ohashi, K; Sugito, K; Uekusa, S | 1 |
| Lock, JF; Malinowski, M; Martus, P; Neuhaus, P; Stockmann, M | 1 |
| Nishi, S | 1 |
| Abramowicz, D; Hoitsma, AJ; Proot, P; Vanrenterghem, Y; Woodle, ES | 1 |
| Graves, D; Vernino, S | 1 |
| Banno, R; Chikami, T; Fujita, T; Hamazaki, J; Kohno, T; Kuroda, A; Okuno, S; Sakurai, S; Tsuji, T; Yoshida, Y | 1 |
7 review(s) available for fingolimod hydrochloride and tacrolimus
| Article | Year |
|---|---|
Immunosuppressive drugs in paediatric liver transplantation.
Topics: Animals; Child; Child, Preschool; Cyclosporine; Drug Interactions; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Liver Transplantation; Mycophenolic Acid; Propylene Glycols; Sirolimus; Sphingosine; Tacrolimus | 2001 |
Treatment of transplant rejection: are the traditional immunosuppressants good enough?
Topics: Antibodies, Monoclonal; Antimetabolites; Calcineurin Inhibitors; Cyclosporine; Cytokines; Drug Design; Fingolimod Hydrochloride; Graft Rejection; Guanidines; Humans; Immunosuppressive Agents; Lymphocyte Activation; Molecular Structure; Organ Transplantation; Propylene Glycols; Signal Transduction; Sirolimus; Sphingosine; T-Lymphocytes; Tacrolimus; Triterpenes | 2001 |
Renal transplantation: basic concepts and evolution of therapy.
Topics: Antibodies, Monoclonal; Azathioprine; Calcineurin Inhibitors; Cyclosporine; Fingolimod Hydrochloride; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Transplantation; Mycophenolic Acid; Propylene Glycols; Receptors, Interleukin-2; Sirolimus; Sphingosine; Tacrolimus | 2003 |
Current immunosuppressive agents: efficacy, side effects, and utilization.
Topics: Abatacept; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antilymphocyte Serum; Area Under Curve; Basiliximab; Cyclosporine; Daclizumab; Drug Therapy, Combination; Drug Utilization; Everolimus; Fingolimod Hydrochloride; Graft Survival; Humans; Immunoconjugates; Immunoglobulin G; Immunosuppressive Agents; Muromonab-CD3; Mycophenolic Acid; Propylene Glycols; Recombinant Fusion Proteins; Sirolimus; Sphingosine; Tacrolimus | 2003 |
[Immunossupresive drugs in renal transplantation].
Topics: Adrenal Cortex Hormones; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Mycophenolic Acid; Propylene Glycols; Risk Factors; Rituximab; Sirolimus; Sphingosine; Tacrolimus | 2004 |
[Immunosuppressive agents in kidney transplantation].
Topics: Antibodies; Antibodies, Monoclonal, Murine-Derived; Boronic Acids; Bortezomib; Cyclosporine; Everolimus; Fingolimod Hydrochloride; Graft Rejection; Immunosuppressive Agents; Kidney Transplantation; Propylene Glycols; Pyrazines; Rituximab; Sirolimus; Sphingosine; T-Lymphocytes; Tacrolimus; TOR Serine-Threonine Kinases | 2011 |
Immunotherapies in neurologic disorders.
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Cyclophosphamide; Cyclosporine; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Immunosuppressive Agents; Interferon beta-1a; Interferon beta-1b; Interferon-beta; Mitoxantrone; Mycophenolic Acid; Natalizumab; Nervous System Diseases; Peptides; Plasma Exchange; Propylene Glycols; Rituximab; Sphingosine; Tacrolimus | 2012 |
1 trial(s) available for fingolimod hydrochloride and tacrolimus
| Article | Year |
|---|---|
FTY720 combined with tacrolimus in de novo renal transplantation: 1-year, multicenter, open-label randomized study.
Topics: Adolescent; Adult; Aged; Cyclosporine; Drug Therapy, Combination; Female; Fingolimod Hydrochloride; Follow-Up Studies; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Prognosis; Propylene Glycols; Sphingosine; Survival Rate; Tacrolimus; Young Adult | 2011 |
18 other study(ies) available for fingolimod hydrochloride and tacrolimus
| Article | Year |
|---|---|
Effect of peritransplant FTY720 alone or in combination with posttransplant FK 506 in a rat model of cardiac allotransplantation.
Topics: Abdomen; Animals; Drug Administration Schedule; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Intraoperative Period; Kidney Function Tests; Liver Function Tests; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Regression Analysis; Sphingosine; Tacrolimus; Transplantation, Heterotopic; Transplantation, Homologous; Weight Gain | 1997 |
FTY720, a novel immunosuppressant, induces sequestration of circulating mature lymphocytes by acceleration of lymphocyte homing in rats. I. FTY720 selectively decreases the number of circulating mature lymphocytes by acceleration of lymphocyte homing.
Topics: Animals; CD11 Antigens; Cell Line; Cell Movement; Cyclosporine; Fingolimod Hydrochloride; Graft Survival; Immunosuppressive Agents; Interleukin-2; Lymphocyte Count; Lymphocytes; Male; Propylene Glycols; Rats; Rats, Inbred F344; Skin Transplantation; Sphingosine; Tacrolimus | 1998 |
Effect of peritransplant FTY720 alone or in combination with post-transplant tacrolimus in a rat model of cardiac allotransplantation.
Topics: Animals; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Kidney; Leukocyte Count; Liver; Propylene Glycols; Rats; Rats, Inbred Lew; Sphingosine; Tacrolimus; Transplantation, Homologous | 1998 |
FTY720 compares with FK 506 as rescue therapy in rat heterotopic cardiac transplantation.
Topics: Animals; Drug Administration Schedule; Fingolimod Hydrochloride; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Sphingosine; Tacrolimus; Time Factors; Transplantation, Heterotopic | 1998 |
Combination effect of tacrolimus and FTY720 in liver transplantation in rats.
Topics: Animals; Apoptosis; Cytokines; Fingolimod Hydrochloride; Gene Expression Regulation; Graft Rejection; Graft Survival; Immunosuppressive Agents; In Situ Nick-End Labeling; Liver Transplantation; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; RNA, Messenger; Sphingosine; Tacrolimus; Transcription, Genetic; Transplantation, Homologous | 1999 |
Immunosuppressive therapy using FTY720 combined with tacrolimus in rat liver transplantation.
Topics: Animals; Apoptosis; CD2 Antigens; Drug Combinations; Fingolimod Hydrochloride; Graft Survival; Granzymes; Immunosuppressive Agents; In Situ Nick-End Labeling; Interferon-gamma; Interleukin-2; Liver; Liver Transplantation; Lymphocytes; Male; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; RNA, Messenger; Serine Endopeptidases; Sphingosine; Tacrolimus | 2000 |
Prolongation of canine liver allograft survival by a novel immunosuppressant, FTY720: effect of monotherapy and combined treatment with conventional drugs.
Topics: Animals; Bilirubin; Cyclosporine; Dogs; Drug Therapy, Combination; Female; Fingolimod Hydrochloride; Graft Rejection; Graft Survival; Immunosuppressive Agents; Liver Transplantation; Propylene Glycols; Sphingosine; Survival Rate; Tacrolimus; Time Factors | 2000 |
FTY720 prevents development of experimental autoimmune myocarditis through reduction of circulating lymphocytes.
Topics: Analysis of Variance; Animals; Autoimmune Diseases; Body Weight; Fingolimod Hydrochloride; Immunosuppressive Agents; Injections, Intraperitoneal; Lymphocyte Count; Lymphocytes; Male; Myocarditis; Organ Size; Propylene Glycols; Rats; Rats, Inbred Lew; Sphingosine; Tacrolimus | 2000 |
Effect of FTY720, a novel immunosuppressant, on adjuvant-induced arthritis in rats.
Topics: Animals; Arthritis, Experimental; Cyclosporine; Edema; Fingolimod Hydrochloride; Immunosuppressive Agents; Leukocyte Count; Lymphocytes; Male; Monocytes; Mycobacterium tuberculosis; Neutrophils; Osteolysis; Propylene Glycols; Rats; Rats, Inbred Lew; Sphingosine; Tacrolimus | 2000 |
Coexpression of CD4 and CD8alpha on rat T-cells in whole blood: a sensitive marker for monitoring T-cell immunosuppressive drugs.
Topics: Animals; Biomarkers; CD4 Antigens; CD4-Positive T-Lymphocytes; CD8 Antigens; Concanavalin A; Cyclosporine; Everolimus; Fingolimod Hydrochloride; Flow Cytometry; Guanidines; Immunosuppressive Agents; Mitogens; Propylene Glycols; Rats; Rats, Inbred Lew; Sirolimus; Sphingosine; Tacrolimus | 2001 |
A new immunosuppressant, FTY720, in canine kidney transplantation: effect of single-drug, induction and combination treatments.
Topics: Animals; Blood Cell Count; Coronary Vessels; Cyclosporine; Dogs; Drug Therapy, Combination; Female; Fingolimod Hydrochloride; Graft Rejection; Graft Survival; Immunosuppressive Agents; Intestines; Kidney; Liver Transplantation; Lung; Propylene Glycols; Sphingosine; Survival Analysis; Tacrolimus | 2004 |
[Study of the effects of immunosuppressive agents on human islet cells in vitro].
Topics: Cell Separation; Cell Survival; Cells, Cultured; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Islets of Langerhans; Propylene Glycols; Sirolimus; Sphingosine; Tacrolimus | 2005 |
Tacrolimus in combination with FTY720--an analysis of renal and blood parameters.
Topics: Animals; Biomarkers; Blood Glucose; Creatinine; Diabetes Mellitus; Diuresis; Drug Synergism; Fingolimod Hydrochloride; Immunosuppressive Agents; Kidney; Lymphocyte Count; Lymphopenia; Male; Mice; Mice, Inbred C57BL; Potassium; Propylene Glycols; Sodium; Sphingosine; Tacrolimus | 2006 |
Skin allograft survival and analysis of renal parameters after FTY720 + tacrolimus treatment in mice.
Topics: Animals; Fingolimod Hydrochloride; Flow Cytometry; Graft Survival; Immunosuppressive Agents; Kidney; Kidney Function Tests; Mice; Propylene Glycols; Skin Transplantation; Sphingosine; Tacrolimus; Transplantation, Homologous | 2008 |
Treatment with immunosuppressants FTY720 and tacrolimus promotes functional recovery after spinal cord injury in rats.
Topics: Animals; Axons; Evoked Potentials, Somatosensory; Fingolimod Hydrochloride; Immunosuppressive Agents; Male; Myelin Sheath; Propylene Glycols; Rats; Rats, Sprague-Dawley; Recovery of Function; Sphingosine; Spinal Cord Injuries; Tacrolimus | 2009 |
Effect of combined treatment with FK506, FTY720, and ex vivo graft irradiation in rat small bowel transplantation: expression of mucosal addressin cell adhesion molecule-1.
Topics: Animals; Combined Modality Therapy; Fingolimod Hydrochloride; Immunoglobulins; Immunosuppressive Agents; Intestine, Small; Mucoproteins; Propylene Glycols; Rats; Sphingosine; Tacrolimus; Transplants | 2010 |
Systemic influence of immunosuppressive drugs on small and large bowel transport and barrier function.
Topics: Animals; Biological Transport; Cyclosporine; Diarrhea; Everolimus; Fingolimod Hydrochloride; Glucose; Immunosuppressive Agents; Intestinal Absorption; Intestine, Large; Intestine, Small; Male; Mycophenolic Acid; Propylene Glycols; Rats; Rats, Wistar; Sirolimus; Sphingosine; Tacrolimus | 2011 |
Therapeutic approach to mite-induced intractable dermatitis using novel immunomodulator FTY720 ointment (fingolimod) in NC/Nga mice.
Topics: Animals; Dermatitis, Atopic; Dermatophagoides farinae; Disease Models, Animal; Female; Filaggrin Proteins; Fingolimod Hydrochloride; Immunoglobulin E; Immunologic Factors; Immunosuppressive Agents; Intermediate Filament Proteins; Mice; Ointments; Tacrolimus | 2016 |