Page last updated: 2024-09-02

fingolimod hydrochloride and osu-2s

fingolimod hydrochloride has been researched along with osu-2s in 4 studies

Compound Research Comparison

Studies
(fingolimod hydrochloride)
Trials
(fingolimod hydrochloride)
Recent Studies (post-2010)
(fingolimod hydrochloride)
Studies
(osu-2s)
Trials
(osu-2s)
Recent Studies (post-2010) (osu-2s)
2,7711572,062707

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Berman-Booty, LD; Byrd, JC; Chen, CS; Chou, CC; Hung, JH; Kogure, T; Kulp, SK; Ma, Y; Muthusamy, N; Omar, HA; Patel, T; Terracciano, L; Wang, D1
Byrd, JC; Chen, CS; Lee, LJ; Lee, RJ; Li, H; Mao, Y; Muthusamy, N; Phelps, MA; Wang, J; Yan, R; Zhao, Y1
Baiocchi, R; Baskar, S; Byrd, JC; Chen, CS; Chiang, CL; Frissora, FW; Klisovic, R; Lee, LJ; Lee, RJ; Mani, R; Mo, X; Muthusamy, N; Phelps, MA; Rader, C; Yan, R1
Bennett, C; Byrd, JC; Chen, M; Coss, CC; Cui, F; Freed, C; Goswami, S; Jennings, RN; Kisseberth, WC; Kulp, SK; Lewis, S; Malbrue, R; Mani, R; Muthusamy, N; Phelps, MA; Schaaf, LJ; Schober, KK; Wang, D; Xie, Z1

Other Studies

4 other study(ies) available for fingolimod hydrochloride and osu-2s

ArticleYear
Antitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma.
    Hepatology (Baltimore, Md.), 2011, Volume: 53, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Fingolimod Hydrochloride; Hepatocytes; Humans; Liver Neoplasms; Mice; Mice, Nude; Propylene Glycols; Protein Kinase C-delta; Reactive Oxygen Species; Signal Transduction; Sphingosine; Xenograft Model Antitumor Assays

2011
Quantification of OSU-2S, a novel derivative of FTY720, in mouse plasma by liquid chromatography-tandem mass spectrometry.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 98

    Topics: Animals; Chromatography, Liquid; Female; Fingolimod Hydrochloride; Half-Life; Mice; Mice, Inbred ICR; Plasma; Propylene Glycols; Sphingosine; Tandem Mass Spectrometry

2014
ROR1-targeted delivery of OSU-2S, a nonimmunosuppressive FTY720 derivative, exerts potent cytotoxicity in mantle-cell lymphoma in vitro and in vivo.
    Experimental hematology, 2015, Volume: 43, Issue:9

    Topics: Animals; Antibodies, Monoclonal, Humanized; Antigens, Differentiation, B-Lymphocyte; Antigens, Neoplasm; Cytotoxins; Drug Delivery Systems; Fingolimod Hydrochloride; Histocompatibility Antigens Class II; Humans; Lymphoma, Mantle-Cell; Mice; Mice, Inbred NOD; Propylene Glycols; Receptor Tyrosine Kinase-like Orphan Receptors; Sphingosine; Xenograft Model Antitumor Assays

2015
Pharmacokinetics and Tolerability of the Novel Non-immunosuppressive Fingolimod Derivative, OSU-2S, in Dogs and Comparisons with Data in Mice and Rats.
    The AAPS journal, 2020, 07-16, Volume: 22, Issue:4

    Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Data Analysis; Dogs; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Haplorhini; Humans; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Propylene Glycols; Rats; Rats, Sprague-Dawley; Sphingosine

2020