Page last updated: 2024-09-02

fingolimod hydrochloride and mycophenolic acid

fingolimod hydrochloride has been researched along with mycophenolic acid in 24 studies

Compound Research Comparison

Studies
(fingolimod hydrochloride)
Trials
(fingolimod hydrochloride)
Recent Studies (post-2010)
(fingolimod hydrochloride)
Studies
(mycophenolic acid)
Trials
(mycophenolic acid)
Recent Studies (post-2010) (mycophenolic acid)
2,7711572,0629,0291,5063,772

Protein Interaction Comparison

ProteinTaxonomyfingolimod hydrochloride (IC50)mycophenolic acid (IC50)
Inosine-5'-monophosphate dehydrogenase 2Homo sapiens (human)0.1496
Glutamate receptor 1Rattus norvegicus (Norway rat)0.014
Glutamate receptor 2Rattus norvegicus (Norway rat)0.014
Glutamate receptor 3Rattus norvegicus (Norway rat)0.014
Glutamate receptor 4Rattus norvegicus (Norway rat)0.014
Inosine-5'-monophosphate dehydrogenase 1 Homo sapiens (human)0.0772
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.011
Inosine-5'-monophosphate dehydrogenaseCryptococcus neoformans var. neoformans JEC210.12

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's19 (79.17)29.6817
2010's4 (16.67)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Kelly, DA; van Mourik, ID1
Hof, RP; Matsumoto, Y1
Baumlin, Y; Hof, A; Hof, RP; Matsumoto, Y1
Braun, WE1
McDonald, RA; Nemeth, TL; Smith, JM1
Birnbaum, F; Braunstein, S; Claas, F; Mayer, K; Reinhard, T; Reis, A; Sundmacher, R1
Cerio, J; Gabardi, S1
Baczkowska, T; Durlik, M1
Felipe, CR; Garcia, R; Machado, PG; Medina-Pestana, JO; Park, SI; Schmouder, R; Skerjanec, A; Tedesco-Silva, H1
Boira, JG; Charpentier, B; Kahan, BD; Madsen, S; Mourad, G; Mulgaonkar, S; Nashan, B; Pellet, P; Tedesco-Silva, H; Vanrenterghem, Y; Weimar, W1
Cozzi, E; Schuurman, HJ; Smith, HT1
Harada, T; Kanekake, H; Nishikido, M1
Ijzermans, JN; Mol, WM; Vaessen, LM; van Besouw, NM; Weimar, W1
Aradhye, S; Budde, K; Charpentier, B; Eisenberger, U; Eris, J; Hmissi, A; Klempnauer, J; Nashan, B; Pallardo, LM; Rostaing, L; Salvadori, M; Schena, FP1
Cibrik, D; Esmeraldo, Rde M; Gugliuzza, KK; Kahan, BD; Lord, H; Mulgaonkar, S; Pescovitz, MD; Rajagopalan, PR; Rees, MA; Salvadori, M; Slade, JM; Tedesco-Silva, H1
Cremer, M; Ferguson, R; Grinyó, J; Jardine, A; Juarez, F; Klinger, M; Mulgaonkar, S; Oppenheimer, F; Ostrowski, M; Preiss, R; Torres, A; Walker, R1
Burton, JM; O'Connor, P1
Cremer, M; Hmissi, A; Lang, P; Mayer, H; Schena, FP; Shoker, A; Sommerer, C; Szakaly, P; Tedesco-Silva, H; Yoshimura, N1
Abdollahi, A; Domhan, S; Zeier, M1
Lock, JF; Malinowski, M; Martus, P; Neuhaus, P; Stockmann, M1
Abramowicz, D; Hoitsma, AJ; Proot, P; Vanrenterghem, Y; Woodle, ES1
Lei, T; Liu, G; Peng, J; Sun, C; Wang, R; Wu, T; Xu, K; Zhang, L; Zhao, Y1
Graves, D; Vernino, S1
Altincatal, A; Berdofe, A; Centonze, D; de Moor, C; Jung, E; Kim, M; Nagpal, A; Naylor, ML; Popescu, C; Radhakrishnan, M; Rajbhandari, R; Reder, AT; Sandrock, AW; Smirnakis, K1

Reviews

8 review(s) available for fingolimod hydrochloride and mycophenolic acid

ArticleYear
Immunosuppressive drugs in paediatric liver transplantation.
    Paediatric drugs, 2001, Volume: 3, Issue:1

    Topics: Animals; Child; Child, Preschool; Cyclosporine; Drug Interactions; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Liver Transplantation; Mycophenolic Acid; Propylene Glycols; Sirolimus; Sphingosine; Tacrolimus

2001
Renal transplantation: basic concepts and evolution of therapy.
    Journal of clinical apheresis, 2003, Volume: 18, Issue:3

    Topics: Antibodies, Monoclonal; Azathioprine; Calcineurin Inhibitors; Cyclosporine; Fingolimod Hydrochloride; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Transplantation; Mycophenolic Acid; Propylene Glycols; Receptors, Interleukin-2; Sirolimus; Sphingosine; Tacrolimus

2003
Current immunosuppressive agents: efficacy, side effects, and utilization.
    Pediatric clinics of North America, 2003, Volume: 50, Issue:6

    Topics: Abatacept; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antilymphocyte Serum; Area Under Curve; Basiliximab; Cyclosporine; Daclizumab; Drug Therapy, Combination; Drug Utilization; Everolimus; Fingolimod Hydrochloride; Graft Survival; Humans; Immunoconjugates; Immunoglobulin G; Immunosuppressive Agents; Muromonab-CD3; Mycophenolic Acid; Propylene Glycols; Recombinant Fusion Proteins; Sirolimus; Sphingosine; Tacrolimus

2003
Future immunosuppressive agents in solid-organ transplantation.
    Progress in transplantation (Aliso Viejo, Calif.), 2004, Volume: 14, Issue:2

    Topics: Drug Approval; Drug Interactions; Drug Monitoring; Everolimus; Fingolimod Hydrochloride; Forecasting; Graft Survival; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Mycophenolic Acid; Organ Transplantation; Propylene Glycols; Safety; Sirolimus; Sphingosine; Transplantation Immunology; Treatment Outcome

2004
[Immunossupresive drugs in renal transplantation].
    Polskie Archiwum Medycyny Wewnetrznej, 2004, Volume: 112 Spec No

    Topics: Adrenal Cortex Hormones; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antibodies, Neoplasm; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Mycophenolic Acid; Propylene Glycols; Risk Factors; Rituximab; Sirolimus; Sphingosine; Tacrolimus

2004
[Molecular action mechanisms of the therapeutic agents for kidney diseases: Immunosuppressants].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 2

    Topics: Antibodies, Monoclonal; Azathioprine; Basiliximab; Cyclophosphamide; Cyclosporine; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid; Propylene Glycols; Recombinant Fusion Proteins; Ribonucleosides; Sphingosine

2006
Novel oral agents for multiple sclerosis.
    Current neurology and neuroscience reports, 2007, Volume: 7, Issue:3

    Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cladribine; Clinical Trials as Topic; Dimethyl Fumarate; Fingolimod Hydrochloride; Fumarates; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Interferon beta-1b; Interferon-beta; Isoxazoles; Leflunomide; Minocycline; Multiple Sclerosis; Mycophenolic Acid; Propylene Glycols; Pyridones; Quinolones; Sphingosine

2007
Immunotherapies in neurologic disorders.
    The Medical clinics of North America, 2012, Volume: 96, Issue:3

    Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Cyclophosphamide; Cyclosporine; Fingolimod Hydrochloride; Glatiramer Acetate; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Immunosuppressive Agents; Interferon beta-1a; Interferon beta-1b; Interferon-beta; Mitoxantrone; Mycophenolic Acid; Natalizumab; Nervous System Diseases; Peptides; Plasma Exchange; Propylene Glycols; Rituximab; Sphingosine; Tacrolimus

2012

Trials

7 trial(s) available for fingolimod hydrochloride and mycophenolic acid

ArticleYear
Pharmacokinetic/pharmacodynamic relationships of FTY720 in kidney transplant recipients.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2005, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Aged; Cyclosporine; Dose-Response Relationship, Drug; Female; Fingolimod Hydrochloride; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Lymphocyte Count; Lymphocytes; Lymphopenia; Male; Middle Aged; Mycophenolic Acid; Propylene Glycols; Sphingosine; Time Factors

2005
FTY720, a novel immunomodulator: efficacy and safety results from the first phase 2A study in de novo renal transplantation.
    Transplantation, 2005, Jun-15, Volume: 79, Issue:11

    Topics: Adolescent; Adult; Aged; Biopsy; Dose-Response Relationship, Drug; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Infections; Kidney Transplantation; Middle Aged; Mycophenolic Acid; Postoperative Complications; Propylene Glycols; Safety; Sphingosine; Time Factors; Treatment Outcome

2005
FTY720 treatment of kidney transplant patients: a differential effect on B cells, naïve T cells, memory T cells and NK cells.
    Transplant immunology, 2006, Volume: 15, Issue:4

    Topics: B-Lymphocytes; Fingolimod Hydrochloride; Granulocytes; Humans; Immunosuppressive Agents; Kidney Transplantation; Killer Cells, Natural; Leukocytes, Mononuclear; Monocytes; Mycophenolic Acid; Propylene Glycols; Receptors, CCR5; Receptors, CCR7; Receptors, Chemokine; Receptors, CXCR3; Sphingosine; T-Lymphocyte Subsets; T-Lymphocytes

2006
FTY720 versus MMF with cyclosporine in de novo renal transplantation: a 1-year, randomized controlled trial in Europe and Australasia.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2006, Volume: 6, Issue:12

    Topics: Adult; Australasia; Creatinine; Cyclosporine; Drug Therapy, Combination; Europe; Fingolimod Hydrochloride; Graft Survival; Histocompatibility Testing; Humans; Kidney Transplantation; Liver Function Tests; Mycophenolic Acid; Propylene Glycols; Safety; Sphingosine

2006
Randomized controlled trial of FTY720 versus MMF in de novo renal transplantation.
    Transplantation, 2006, Dec-27, Volume: 82, Issue:12

    Topics: Adult; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Propylene Glycols; Sphingosine

2006
FTY720 versus mycophenolate mofetil in de novo renal transplantation: six-month results of a double-blind study.
    Transplantation, 2007, Oct-15, Volume: 84, Issue:7

    Topics: Adult; Biopsy; Bradycardia; Cohort Studies; Cyclosporine; Double-Blind Method; Female; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Mycophenolic Acid; Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine

2007
FTY720 combined with tacrolimus in de novo renal transplantation: 1-year, multicenter, open-label randomized study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2011, Volume: 26, Issue:11

    Topics: Adolescent; Adult; Aged; Cyclosporine; Drug Therapy, Combination; Female; Fingolimod Hydrochloride; Follow-Up Studies; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Prognosis; Propylene Glycols; Sphingosine; Survival Rate; Tacrolimus; Young Adult

2011

Other Studies

9 other study(ies) available for fingolimod hydrochloride and mycophenolic acid

ArticleYear
Effects of mycophenolate sodium with or without FTY720 in a DA-to-Lewis rat heart transplantation model.
    Transplantation proceedings, 2002, Volume: 34, Issue:7

    Topics: Animals; Disease Models, Animal; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Mycophenolic Acid; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Sphingosine; Time Factors; Transplantation, Homologous

2002
Efficacy of mycophenolate sodium as monotherapy and in combination with FTY720 in a DA-to-Lewis-rat heart-transplantation model.
    Transplantation, 2002, Nov-27, Volume: 74, Issue:10

    Topics: Animals; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Leukocyte Count; Male; Mycophenolic Acid; Myocardium; Propylene Glycols; Rats; Rats, Inbred Lew; Sphingosine; Transplantation, Homologous

2002
FTY720 prolongs clear corneal allograft survival with a differential effect on different lymphocyte populations.
    The British journal of ophthalmology, 2004, Volume: 88, Issue:7

    Topics: Animals; Antigens, CD; Corneal Transplantation; Female; Fingolimod Hydrochloride; Graft Rejection; Immunosuppressive Agents; Lymphocyte Count; Lymphocytes; Mycophenolic Acid; Propylene Glycols; Rats; Rats, Inbred F344; Rats, Inbred Lew; Sphingosine; Weight Loss

2004
Tolerability of cyclosphosphamide and methotrexate induction immunosuppression in nonhuman primates.
    Toxicology, 2005, Sep-15, Volume: 213, Issue:1-2

    Topics: Animals; Cyclophosphamide; Cyclosporine; Drug Synergism; Everolimus; Female; Fingolimod Hydrochloride; Immunosuppressive Agents; Leukocyte Count; Macaca fascicularis; Male; Methotrexate; Mycophenolic Acid; Organ Transplantation; Papio; Propylene Glycols; Sirolimus; Sphingosine

2005
Impact of long-term therapy with FTY720 or mycophenolate mofetil on cardiac conduction and rhythm in stable adult renal transplant patients.
    Transplantation, 2007, Mar-15, Volume: 83, Issue:5

    Topics: Adrenergic Antagonists; Adult; Female; Fingolimod Hydrochloride; Heart Conduction System; Heart Rate; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Propylene Glycols; Sphingosine

2007
Immunosuppressive therapy and post-transplant malignancy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:4

    Topics: Azathioprine; Calcineurin Inhibitors; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Mycophenolic Acid; Neoplasms; Organ Transplantation; Propylene Glycols; Protein Kinases; Sphingosine; TOR Serine-Threonine Kinases

2009
Systemic influence of immunosuppressive drugs on small and large bowel transport and barrier function.
    Transplant international : official journal of the European Society for Organ Transplantation, 2011, Volume: 24, Issue:2

    Topics: Animals; Biological Transport; Cyclosporine; Diarrhea; Everolimus; Fingolimod Hydrochloride; Glucose; Immunosuppressive Agents; Intestinal Absorption; Intestine, Large; Intestine, Small; Male; Mycophenolic Acid; Propylene Glycols; Rats; Rats, Wistar; Sirolimus; Sphingosine; Tacrolimus

2011
Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo.
    Transplant immunology, 2012, Volume: 27, Issue:1

    Topics: Adoptive Transfer; Animals; CD4-Positive T-Lymphocytes; Cell Count; Cyclophosphamide; Cyclosporine; Fingolimod Hydrochloride; Forkhead Transcription Factors; Immune Tolerance; Immunity; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Isoxazoles; Leflunomide; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, Transgenic; Mycophenolic Acid; Ovalbumin; Propylene Glycols; Sirolimus; Sphingosine; Spleen; T-Lymphocytes, Regulatory

2012
COVID-19 in Patients with Multiple Sclerosis: Associations with Disease-Modifying Therapies.
    CNS drugs, 2021, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alemtuzumab; Azathioprine; Black or African American; Cladribine; Comorbidity; COVID-19; Crotonates; Cyclophosphamide; Cyclosporine; Databases, Factual; Dimethyl Fumarate; Female; Fingolimod Hydrochloride; Hospitalization; Humans; Hydroxybutyrates; Immunologic Factors; Immunosuppressive Agents; Incidence; Interferon-beta; Logistic Models; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Mitoxantrone; Multiple Sclerosis; Mycophenolic Acid; Natalizumab; Nitriles; Obesity; Risk Factors; Rituximab; SARS-CoV-2; Toluidines; United States; White People; Young Adult

2021