Page last updated: 2024-09-02

fingolimod hydrochloride and mocetinostat

fingolimod hydrochloride has been researched along with mocetinostat in 9 studies

Compound Research Comparison

Studies
(fingolimod hydrochloride)
Trials
(fingolimod hydrochloride)
Recent Studies (post-2010)
(fingolimod hydrochloride)
Studies
(mocetinostat)
Trials
(mocetinostat)
Recent Studies (post-2010) (mocetinostat)
2,7711572,06221,7353908,606

Protein Interaction Comparison

ProteinTaxonomyfingolimod hydrochloride (IC50)mocetinostat (IC50)
Histone deacetylase 3Homo sapiens (human)0.7851
Nuclear receptor corepressor 1Homo sapiens (human)0.022
Cytochrome P450 3A4Homo sapiens (human)0.57
Cytochrome P450 2D6Homo sapiens (human)0.102
Cytochrome P450 2C19Homo sapiens (human)0.102
Histone deacetylase 4Homo sapiens (human)0.5717
Histone deacetylase 1Homo sapiens (human)0.3433
Histone deacetylase 7Homo sapiens (human)0.6725
Histone deacetylase 2Homo sapiens (human)0.3537
Histone deacetylase 11 Homo sapiens (human)0.6386
Histone deacetylase 8Homo sapiens (human)0.6725
Histone deacetylase 6Homo sapiens (human)0.5717
Histone deacetylase 5Homo sapiens (human)0.6725
Nuclear receptor corepressor 2Homo sapiens (human)0.045

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's6 (66.67)29.6817
2010's1 (11.11)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Fujimura, A; Hashizume, K; Kanno, T; Kitoh, Y; Kobayashi, E; Miyashita, F; Mizuta, K; Mori, M; Ohmori, M1
Amersi, FF; Anselmo, D; Brinkmann, V; Busuttil, RW; Coito, AJ; Farmer, DG; Gao, F; Katori, M; Ke, B; Kupiec-Weglinski, JW; Lassman, C; Shen, XD1
Burne, MJ; Garcia, JG; Hassoun, PM; McVerry, BJ; Pearse, D; Peng, X; Rabb, H; Sammani, S; Tuder, RM1
Itoh, M; Kataoka, H; Kuno, A; Nakao, H; Ogawa, K; Ohara, H; Okamoto, T; Sano, H; Shirai, T; Tang, M; Yamada, T1
Awad, AS; Foss, FW; Huang, L; Li, L; Lynch, KR; Macdonald, TL; Okusa, MD; Ye, H1
Frink, M; Hildebrand, F; Kaudel, CP; Klempnauer, J; Krettek, C; Pape, HC; van Griensven, M; Winkler, M1
Cui, NQ; Li, DH; Liu, HB; Wang, Q; Xue, XP1
Brown, TS; Davis, TA; Elster, EA; Graybill, JC; Hawksworth, JS; Tadaki, DK; Wallace, SM1
Chen, M; Chen, SF; Li, ZY; Little, MA; Sun, XJ; Wang, C; Wang, LY; Zhao, MH1

Other Studies

9 other study(ies) available for fingolimod hydrochloride and mocetinostat

ArticleYear
Effect of pretreatment with FTY720 and cyclosporin on ischaemia-reperfusion injury of the liver in rats.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:12

    Topics: Animals; Cyclosporine; Fingolimod Hydrochloride; Immunosuppressive Agents; Leukocyte Count; Leukocytes, Mononuclear; Liver; Male; Neutrophil Activation; Peroxidase; Propylene Glycols; Rats; Rats, Wistar; Reperfusion Injury; Sphingosine; Transaminases; Tumor Necrosis Factor-alpha

1999
FTY720: a novel approach to the treatment of hepatic ischemia-reperfusion injury.
    Transplantation proceedings, 2002, Volume: 34, Issue:5

    Topics: Animals; Fingolimod Hydrochloride; Immunosuppressive Agents; Liver; Liver Circulation; Lymphocyte Count; Peroxidase; Propylene Glycols; Rats; Rats, Inbred Lew; Reperfusion Injury; Sphingosine

2002
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury.
    American journal of respiratory and critical care medicine, 2004, Jun-01, Volume: 169, Issue:11

    Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Disease Models, Animal; Endothelial Cells; Endotoxins; Fingolimod Hydrochloride; Immunosuppressive Agents; Kidney; Kidney Diseases; Lipopolysaccharides; Lung; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Neutrophils; Organ Size; Perfusion; Peroxidase; Pneumonia; Propylene Glycols; Respiratory Distress Syndrome; Sphingosine; Time Factors

2004
FTY720, an immunosuppressant, attenuates chronic pancreatitis in rats by suppressing T-cell infiltration.
    Pancreas, 2005, Volume: 30, Issue:3

    Topics: Animals; Body Weight; Fingolimod Hydrochloride; Hydroxyproline; Immunosuppressive Agents; Interferon-gamma; Male; Organ Size; Pancreas; Pancreatitis, Chronic; Peroxidase; Propylene Glycols; Rats; Rats, Wistar; RNA, Messenger; Sphingosine; T-Lymphocytes; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney.
    American journal of physiology. Renal physiology, 2006, Volume: 290, Issue:6

    Topics: Animals; Capillary Permeability; Creatinine; Fingolimod Hydrochloride; Kidney; Leukocytes; Lymphocyte Count; Mice; Mice, Inbred C57BL; Oxadiazoles; Peroxidase; Propylene Glycols; Receptors, Lysosphingolipid; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sphingosine; T-Lymphocytes; Thiophenes

2006
FTY720 improves survival after transient ischemia and reperfusion of the hind limbs.
    The Journal of trauma, 2007, Volume: 63, Issue:2

    Topics: Analysis of Variance; Animals; Biomarkers; Cytokines; Disease Models, Animal; Fingolimod Hydrochloride; Hindlimb; Immunosuppressive Agents; Interleukin-1; Ischemia; Male; Mice; Mice, Inbred C57BL; Peroxidase; Probability; Propylene Glycols; Random Allocation; Reference Values; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Sphingosine; Survival Rate

2007
Sphingosine-1-phosphate and its analogue FTY720 diminish acute pulmonary injury in rats with acute necrotizing pancreatitis.
    Pancreas, 2008, Volume: 36, Issue:3

    Topics: Amylases; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cytokines; Fingolimod Hydrochloride; Lipase; Lung; Lung Injury; Lysophospholipids; Macrophages, Alveolar; Male; NF-kappa B; Pancreatitis, Acute Necrotizing; Peroxidase; Propylene Glycols; Pulmonary Edema; Rats; Rats, Wistar; Sphingosine

2008
Lymphocyte modulation with FTY720 improves hemorrhagic shock survival in swine.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Analysis of Variance; Animals; DNA Primers; Female; Fingolimod Hydrochloride; Gene Expression Regulation; Immunity, Innate; Immunohistochemistry; Immunosuppressive Agents; Liver; Lymph Nodes; Lymphocytes; Male; Neutrophils; Peroxidase; Propylene Glycols; Real-Time Polymerase Chain Reaction; Shock, Hemorrhagic; Sphingosine; Spleen; Swine; Swine Diseases

2012
Sphingosine-1-phosphate receptor modulator FTY720 attenuates experimental myeloperoxidase-ANCA vasculitis in a T cell-dependent manner.
    Clinical science (London, England : 1979), 2020, 06-26, Volume: 134, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antibodies; Apoptosis; Female; Fingolimod Hydrochloride; Hematuria; Humans; Jurkat Cells; Kidney; Lung; Male; Middle Aged; Models, Biological; Peroxidase; Proteinuria; Rats, Inbred WKY; Signal Transduction; Sphingosine-1-Phosphate Receptors; T-Lymphocytes

2020