fingolimod hydrochloride has been researched along with leflunomide in 3 studies
| Studies (fingolimod hydrochloride) | Trials (fingolimod hydrochloride) | Recent Studies (post-2010) (fingolimod hydrochloride) | Studies (leflunomide) | Trials (leflunomide) | Recent Studies (post-2010) (leflunomide) |
|---|---|---|---|---|---|
| 2,771 | 157 | 2,062 | 1,725 | 173 | 659 |
| Protein | Taxonomy | fingolimod hydrochloride (IC50) | leflunomide (IC50) |
|---|---|---|---|
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Mus musculus (house mouse) | 0.03 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.5 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 4.63 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 4.63 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 2.884 | |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Homo sapiens (human) | 5.4 | |
| Dihydroorotate dehydrogenase (quinone), mitochondrial | Rattus norvegicus (Norway rat) | 0.009 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Emre, S; Krieger, NR | 1 |
| Burton, JM; O'Connor, P | 1 |
| Lei, T; Liu, G; Peng, J; Sun, C; Wang, R; Wu, T; Xu, K; Zhang, L; Zhao, Y | 1 |
2 review(s) available for fingolimod hydrochloride and leflunomide
| Article | Year |
|---|---|
Novel immunosuppressants.
Topics: Abatacept; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; CD40 Ligand; Child; Fingolimod Hydrochloride; Guanidines; Humans; Immunoconjugates; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lymphocyte Depletion; Propylene Glycols; Sphingosine; T-Lymphocytes | 2004 |
Novel oral agents for multiple sclerosis.
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cladribine; Clinical Trials as Topic; Dimethyl Fumarate; Fingolimod Hydrochloride; Fumarates; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Interferon beta-1b; Interferon-beta; Isoxazoles; Leflunomide; Minocycline; Multiple Sclerosis; Mycophenolic Acid; Propylene Glycols; Pyridones; Quinolones; Sphingosine | 2007 |
1 other study(ies) available for fingolimod hydrochloride and leflunomide
| Article | Year |
|---|---|
Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo.
Topics: Adoptive Transfer; Animals; CD4-Positive T-Lymphocytes; Cell Count; Cyclophosphamide; Cyclosporine; Fingolimod Hydrochloride; Forkhead Transcription Factors; Immune Tolerance; Immunity; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Isoxazoles; Leflunomide; Lymph Nodes; Mice; Mice, Inbred BALB C; Mice, Nude; Mice, Transgenic; Mycophenolic Acid; Ovalbumin; Propylene Glycols; Sirolimus; Sphingosine; Spleen; T-Lymphocytes, Regulatory | 2012 |