Page last updated: 2024-09-02

fingolimod hydrochloride and lapatinib

fingolimod hydrochloride has been researched along with lapatinib in 2 studies

Compound Research Comparison

Studies
(fingolimod hydrochloride)
Trials
(fingolimod hydrochloride)
Recent Studies (post-2010)
(fingolimod hydrochloride)
Studies
(lapatinib)
Trials
(lapatinib)
Recent Studies (post-2010) (lapatinib)
2,7711572,0621,9193051,442

Protein Interaction Comparison

ProteinTaxonomyfingolimod hydrochloride (IC50)lapatinib (IC50)
Bile salt export pumpHomo sapiens (human)7.375
Epidermal growth factor receptorHomo sapiens (human)0.0827
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0537
Platelet-derived growth factor receptor betaHomo sapiens (human)8.5
D(1A) dopamine receptorSus scrofa (pig)0.06
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.1659
Alpha-1A adrenergic receptor Sus scrofa (pig)0.06
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)3.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Hino, H; Hiramoto, M; Kazama, H; Lorenzo, A; Miyazawa, K; Moriya, S; Okuma, T; Ota, K; Takano, N; Yokota, A1
Hiramoto, M; Hirota, A; Kazama, H; Miyazaki, M; Miyazawa, K; Ogawa, M; Ota, K; Suzuki, S; Takano, N1

Other Studies

2 other study(ies) available for fingolimod hydrochloride and lapatinib

ArticleYear
Fingolimod sensitizes EGFR wild‑type non‑small cell lung cancer cells to lapatinib or sorafenib and induces cell cycle arrest.
    Oncology reports, 2019, Volume: 42, Issue:1

    Topics: A549 Cells; Autophagy-Related Proteins; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Drug Repositioning; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Fingolimod Hydrochloride; Humans; Lapatinib; Lung Neoplasms; Protein Kinase Inhibitors; Sorafenib

2019
Lysosome‑targeted drug combination induces multiple organelle dysfunctions and non‑canonical death in pancreatic cancer cells.
    Oncology reports, 2022, Volume: 47, Issue:2

    Topics: Aminopyridines; Antineoplastic Agents; Benzimidazoles; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Drug Synergism; Endoplasmic Reticulum Stress; Fingolimod Hydrochloride; Humans; Hydroxychloroquine; Lapatinib; Lysosomes; Pancreatic Neoplasms; Sphingosine 1 Phosphate Receptor Modulators

2022