fingolimod hydrochloride has been researched along with isoproterenol in 1 studies
| Studies (fingolimod hydrochloride) | Trials (fingolimod hydrochloride) | Recent Studies (post-2010) (fingolimod hydrochloride) | Studies (isoproterenol) | Trials (isoproterenol) | Recent Studies (post-2010) (isoproterenol) |
|---|---|---|---|---|---|
| 2,771 | 157 | 2,062 | 30,780 | 803 | 2,640 |
| Protein | Taxonomy | fingolimod hydrochloride (IC50) | isoproterenol (IC50) |
|---|---|---|---|
| Beta-2 adrenergic receptor | Homo sapiens (human) | 0.246 | |
| Beta-1 adrenergic receptor | Homo sapiens (human) | 0.333 | |
| Beta-2 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 1.77 | |
| Beta-1 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-3 adrenergic receptor | Rattus norvegicus (Norway rat) | 0.2125 | |
| Beta-2 adrenergic receptor | Canis lupus familiaris (dog) | 0.6667 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hunt, TL; Kovarik, JM; Maton, S; Neddermann, D; Riviere, GJ; Schmouder, RL | 1 |
1 trial(s) available for fingolimod hydrochloride and isoproterenol
| Article | Year |
|---|---|
A mechanistic study to assess whether isoproterenol can reverse the negative chronotropic effect of fingolimod.
Topics: Administration, Oral; Adrenergic beta-Agonists; Adult; Area Under Curve; Atrial Fibrillation; Bradycardia; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Fingolimod Hydrochloride; Heart Rate; Humans; Infusions, Intravenous; Isoproterenol; Male; Patient Dropouts; Propylene Glycols; Receptors, Lysosphingolipid; Sphingosine; Tachycardia; Time Factors | 2008 |