Page last updated: 2024-09-02

fingolimod hydrochloride and gdc 0449

fingolimod hydrochloride has been researched along with gdc 0449 in 2 studies

Compound Research Comparison

Studies
(fingolimod hydrochloride)
Trials
(fingolimod hydrochloride)
Recent Studies (post-2010)
(fingolimod hydrochloride)
Studies
(gdc 0449)
Trials
(gdc 0449)
Recent Studies (post-2010) (gdc 0449)
2,7711572,06266668611

Protein Interaction Comparison

ProteinTaxonomyfingolimod hydrochloride (IC50)gdc 0449 (IC50)
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.02
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.02
Smoothened homologMus musculus (house mouse)0.07
Sonic hedgehog proteinHomo sapiens (human)0.8825
Sonic hedgehog proteinMus musculus (house mouse)0.0077
Smoothened homologHomo sapiens (human)0.0222
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.4

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Garland, SL1
Dintsios, CM; Rasch, A1

Reviews

2 review(s) available for fingolimod hydrochloride and gdc 0449

ArticleYear
Are GPCRs still a source of new targets?
    Journal of biomolecular screening, 2013, Volume: 18, Issue:9

    Topics: Anilides; Antineoplastic Agents; Binding Sites; Crystallography, X-Ray; Databases, Chemical; Drug Design; Fingolimod Hydrochloride; Humans; Immunosuppressive Agents; Ligands; Propylene Glycols; Protein Binding; Pyridines; Receptors, G-Protein-Coupled; Sphingosine

2013
[Subgroups in the early benefit assessment of pharmaceuticals: a methodical review].
    Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen, 2015, Volume: 109, Issue:1

    Topics: Adenosine; Anilides; Axitinib; Drug Approval; Effect Modifier, Epidemiologic; Fingolimod Hydrochloride; Germany; Humans; Imidazoles; Indazoles; National Health Programs; Pyridines; Risk Assessment; Sitagliptin Phosphate; Sofosbuvir; Ticagrelor

2015